FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0603, 156 aa 1>>>pF1KE0603 156 - 156 aa - 156 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0581+/-0.000391; mu= 15.0855+/- 0.025 mean_var=144.4050+/-34.884, 0's: 0 Z-trim(114.7): 208 B-trim: 1313 in 1/51 Lambda= 0.106729 statistics sampled from 24382 (24653) to 24382 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.289), width: 16 Scan time: 5.010 The best scores are: opt bits E(85289) NP_031388 (OMIM: 605133) nuclear cap-binding prote ( 156) 1053 173.1 1.6e-43 NP_001294965 (OMIM: 605133) nuclear cap-binding pr ( 138) 885 147.1 9.4e-36 XP_011510860 (OMIM: 605133) PREDICTED: nuclear cap ( 86) 605 103.7 6.9e-23 XP_011510858 (OMIM: 605133) PREDICTED: nuclear cap ( 86) 605 103.7 6.9e-23 XP_011510859 (OMIM: 605133) PREDICTED: nuclear cap ( 86) 605 103.7 6.9e-23 NP_001036005 (OMIM: 605133) nuclear cap-binding pr ( 103) 441 78.6 3.1e-15 NP_001287744 (OMIM: 602649) cold-inducible RNA-bin ( 168) 222 45.2 5.6e-05 XP_016881726 (OMIM: 602649) PREDICTED: cold-induci ( 168) 222 45.2 5.6e-05 XP_006722700 (OMIM: 602649) PREDICTED: cold-induci ( 172) 222 45.2 5.7e-05 NP_001271 (OMIM: 602649) cold-inducible RNA-bindin ( 172) 222 45.2 5.7e-05 XP_011525970 (OMIM: 602649) PREDICTED: cold-induci ( 202) 222 45.3 6.2e-05 NP_001287758 (OMIM: 602649) cold-inducible RNA-bin ( 297) 222 45.5 7.7e-05 XP_005247760 (OMIM: 602719) PREDICTED: transformer ( 188) 205 42.6 0.00037 NP_001230808 (OMIM: 602719) transformer-2 protein ( 188) 205 42.6 0.00037 XP_011511374 (OMIM: 602719) PREDICTED: transformer ( 188) 205 42.6 0.00037 XP_016862522 (OMIM: 602719) PREDICTED: transformer ( 188) 205 42.6 0.00037 NP_004584 (OMIM: 602719) transformer-2 protein hom ( 288) 206 43.1 0.00042 NP_114381 (OMIM: 603431) eukaryotic translation in ( 228) 193 40.9 0.0015 XP_011514859 (OMIM: 603431) PREDICTED: eukaryotic ( 230) 193 40.9 0.0015 NP_006734 (OMIM: 300027) RNA-binding protein 3 [Ho ( 157) 189 40.0 0.0018 NP_002130 (OMIM: 300199,300238) RNA-binding motif ( 391) 179 39.1 0.0088 >>NP_031388 (OMIM: 605133) nuclear cap-binding protein s (156 aa) initn: 1053 init1: 1053 opt: 1053 Z-score: 902.1 bits: 173.1 E(85289): 1.6e-43 Smith-Waterman score: 1053; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156) 10 20 30 40 50 60 pF1KE0 MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK 70 80 90 100 110 120 130 140 150 pF1KE0 EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ :::::::::::::::::::::::::::::::::::: NP_031 EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 130 140 150 >>NP_001294965 (OMIM: 605133) nuclear cap-binding protei (138 aa) initn: 885 init1: 885 opt: 885 Z-score: 762.8 bits: 147.1 E(85289): 9.4e-36 Smith-Waterman score: 885; 98.5% identity (99.2% similar) in 132 aa overlap (25-156:7-138) 10 20 30 40 50 60 pF1KE0 MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF . :::::::::::::::::::::::::::::::::: NP_001 MVLRKLYAGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF 10 20 30 40 70 80 90 100 110 120 pF1KE0 SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK 50 60 70 80 90 100 130 140 150 pF1KE0 EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ :::::::::::::::::::::::::::::::::::: NP_001 EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 110 120 130 >>XP_011510860 (OMIM: 605133) PREDICTED: nuclear cap-bin (86 aa) initn: 605 init1: 605 opt: 605 Z-score: 531.8 bits: 103.7 E(85289): 6.9e-23 Smith-Waterman score: 605; 100.0% identity (100.0% similar) in 86 aa overlap (71-156:1-86) 50 60 70 80 90 100 pF1KE0 TLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRY :::::::::::::::::::::::::::::: XP_011 MGLDKMKKTACGFCFVEYYSRADAENAMRY 10 20 30 110 120 130 140 150 pF1KE0 INGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 40 50 60 70 80 >>XP_011510858 (OMIM: 605133) PREDICTED: nuclear cap-bin (86 aa) initn: 605 init1: 605 opt: 605 Z-score: 531.8 bits: 103.7 E(85289): 6.9e-23 Smith-Waterman score: 605; 100.0% identity (100.0% similar) in 86 aa overlap (71-156:1-86) 50 60 70 80 90 100 pF1KE0 TLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRY :::::::::::::::::::::::::::::: XP_011 MGLDKMKKTACGFCFVEYYSRADAENAMRY 10 20 30 110 120 130 140 150 pF1KE0 INGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 40 50 60 70 80 >>XP_011510859 (OMIM: 605133) PREDICTED: nuclear cap-bin (86 aa) initn: 605 init1: 605 opt: 605 Z-score: 531.8 bits: 103.7 E(85289): 6.9e-23 Smith-Waterman score: 605; 100.0% identity (100.0% similar) in 86 aa overlap (71-156:1-86) 50 60 70 80 90 100 pF1KE0 TLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRY :::::::::::::::::::::::::::::: XP_011 MGLDKMKKTACGFCFVEYYSRADAENAMRY 10 20 30 110 120 130 140 150 pF1KE0 INGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 40 50 60 70 80 >>NP_001036005 (OMIM: 605133) nuclear cap-binding protei (103 aa) initn: 441 init1: 441 opt: 441 Z-score: 394.6 bits: 78.6 E(85289): 3.1e-15 Smith-Waterman score: 573; 66.0% identity (66.0% similar) in 156 aa overlap (1-156:1-103) 10 20 30 40 50 60 pF1KE0 MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF ::::::::::::::::::::::::::::::::::::::: : NP_001 MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKS-----------------Y--- 10 20 30 40 70 80 90 100 110 120 pF1KE0 SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK ::::::::::::::::::::::::::: NP_001 ---------------------------------AENAMRYINGTRLDDRIIRTDWDAGFK 50 60 130 140 150 pF1KE0 EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ :::::::::::::::::::::::::::::::::::: NP_001 EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 70 80 90 100 >>NP_001287744 (OMIM: 602649) cold-inducible RNA-binding (168 aa) initn: 210 init1: 210 opt: 222 Z-score: 210.3 bits: 45.2 E(85289): 5.6e-05 Smith-Waterman score: 222; 37.4% identity (66.4% similar) in 107 aa overlap (42-147:8-113) 20 30 40 50 60 70 pF1KE0 DSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIM :.::.::: :.:... ..::: :.:..... NP_001 MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVV 10 20 30 80 90 100 110 120 130 pF1KE0 GLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYG-RGRS :. . . :: :: . . ::..:: .:: .: : ::.: . ...:. : :: : NP_001 VKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGS 40 50 60 70 80 90 140 150 pF1KE0 GGQVRDEYRQDYDAGRGGYGKLAQNQ .: : .: ::: NP_001 AGG-RGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSS 100 110 120 130 140 150 >>XP_016881726 (OMIM: 602649) PREDICTED: cold-inducible (168 aa) initn: 210 init1: 210 opt: 222 Z-score: 210.3 bits: 45.2 E(85289): 5.6e-05 Smith-Waterman score: 222; 37.4% identity (66.4% similar) in 107 aa overlap (42-147:8-113) 20 30 40 50 60 70 pF1KE0 DSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIM :.::.::: :.:... ..::: :.:..... XP_016 MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVV 10 20 30 80 90 100 110 120 130 pF1KE0 GLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYG-RGRS :. . . :: :: . . ::..:: .:: .: : ::.: . ...:. : :: : XP_016 VKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGS 40 50 60 70 80 90 140 150 pF1KE0 GGQVRDEYRQDYDAGRGGYGKLAQNQ .: : .: ::: XP_016 AGG-RGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSS 100 110 120 130 140 150 >>XP_006722700 (OMIM: 602649) PREDICTED: cold-inducible (172 aa) initn: 210 init1: 210 opt: 222 Z-score: 210.2 bits: 45.2 E(85289): 5.7e-05 Smith-Waterman score: 222; 37.4% identity (66.4% similar) in 107 aa overlap (42-147:8-113) 20 30 40 50 60 70 pF1KE0 DSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIM :.::.::: :.:... ..::: :.:..... XP_006 MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVV 10 20 30 80 90 100 110 120 130 pF1KE0 GLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYG-RGRS :. . . :: :: . . ::..:: .:: .: : ::.: . ...:. : :: : XP_006 VKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGS 40 50 60 70 80 90 140 150 pF1KE0 GGQVRDEYRQDYDAGRGGYGKLAQNQ .: : .: ::: XP_006 AGG-RGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSS 100 110 120 130 140 150 >>NP_001271 (OMIM: 602649) cold-inducible RNA-binding pr (172 aa) initn: 210 init1: 210 opt: 222 Z-score: 210.2 bits: 45.2 E(85289): 5.7e-05 Smith-Waterman score: 222; 37.4% identity (66.4% similar) in 107 aa overlap (42-147:8-113) 20 30 40 50 60 70 pF1KE0 DSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIM :.::.::: :.:... ..::: :.:..... NP_001 MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVV 10 20 30 80 90 100 110 120 130 pF1KE0 GLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYG-RGRS :. . . :: :: . . ::..:: .:: .: : ::.: . ...:. : :: : NP_001 VKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGS 40 50 60 70 80 90 140 150 pF1KE0 GGQVRDEYRQDYDAGRGGYGKLAQNQ .: : .: ::: NP_001 AGG-RGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSS 100 110 120 130 140 150 156 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:32:26 2016 done: Wed Nov 2 20:32:27 2016 Total Scan time: 5.010 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]