FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0604, 359 aa 1>>>pF1KE0604 359 - 359 aa - 359 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6895+/-0.000407; mu= 6.4304+/- 0.025 mean_var=249.3106+/-53.719, 0's: 0 Z-trim(118.4): 60 B-trim: 0 in 0/57 Lambda= 0.081228 statistics sampled from 31343 (31404) to 31343 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.368), width: 16 Scan time: 7.750 The best scores are: opt bits E(85289) NP_003921 (OMIM: 605215) src kinase-associated pho ( 359) 2452 300.5 3.7e-81 XP_016868260 (OMIM: 605215) PREDICTED: src kinase- ( 359) 2452 300.5 3.7e-81 NP_001290397 (OMIM: 605215) src kinase-associated ( 187) 1291 164.1 2.2e-40 NP_003717 (OMIM: 604969) src kinase-associated pho ( 359) 995 129.8 9.3e-30 NP_001068567 (OMIM: 604969) src kinase-associated ( 358) 992 129.4 1.2e-29 XP_016880746 (OMIM: 604969) PREDICTED: src kinase- ( 335) 851 112.9 1.1e-24 XP_016880749 (OMIM: 604969) PREDICTED: src kinase- ( 265) 839 111.4 2.5e-24 XP_016880748 (OMIM: 604969) PREDICTED: src kinase- ( 265) 839 111.4 2.5e-24 XP_016880747 (OMIM: 604969) PREDICTED: src kinase- ( 270) 839 111.4 2.5e-24 XP_005257812 (OMIM: 604969) PREDICTED: src kinase- ( 341) 691 94.1 4.8e-19 >>NP_003921 (OMIM: 605215) src kinase-associated phospho (359 aa) initn: 2452 init1: 2452 opt: 2452 Z-score: 1578.0 bits: 300.5 E(85289): 3.7e-81 Smith-Waterman score: 2452; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KE0 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QEFQDKGDAEDGEEYDDPFAGPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QEFQDKGDAEDGEEYDDPFAGPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIPEDYDERGELYDDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIPEDYDERGELYDDV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 DHPLPISNPLTSSQPIDDEIYEELPEEEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DHPLPISNPLTSSQPIDDEIYEELPEEEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYAN 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 FYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI 310 320 330 340 350 >>XP_016868260 (OMIM: 605215) PREDICTED: src kinase-asso (359 aa) initn: 2452 init1: 2452 opt: 2452 Z-score: 1578.0 bits: 300.5 E(85289): 3.7e-81 Smith-Waterman score: 2452; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KE0 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QEFQDKGDAEDGEEYDDPFAGPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEFQDKGDAEDGEEYDDPFAGPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIPEDYDERGELYDDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIPEDYDERGELYDDV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 DHPLPISNPLTSSQPIDDEIYEELPEEEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHPLPISNPLTSSQPIDDEIYEELPEEEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYAN 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 FYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI 310 320 330 340 350 >>NP_001290397 (OMIM: 605215) src kinase-associated phos (187 aa) initn: 1291 init1: 1291 opt: 1291 Z-score: 845.9 bits: 164.1 E(85289): 2.2e-40 Smith-Waterman score: 1291; 100.0% identity (100.0% similar) in 187 aa overlap (173-359:1-187) 150 160 170 180 190 200 pF1KE0 ALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEISAPDKRIYQFTAA :::::::::::::::::::::::::::::: NP_001 MNNTLRKDGKKDCCFEISAPDKRIYQFTAA 10 20 30 210 220 230 240 250 260 pF1KE0 SPKDAEEWVQQLKFVLQDMESDIIPEDYDERGELYDDVDHPLPISNPLTSSQPIDDEIYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPKDAEEWVQQLKFVLQDMESDIIPEDYDERGELYDDVDHPLPISNPLTSSQPIDDEIYE 40 50 60 70 80 90 270 280 290 300 310 320 pF1KE0 ELPEEEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYANFYQGLWDCTGAFSDELSFKRGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELPEEEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYANFYQGLWDCTGAFSDELSFKRGD 100 110 120 130 140 150 330 340 350 pF1KE0 VIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI ::::::::::::::::::::::::::::::::::::: NP_001 VIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI 160 170 180 >>NP_003717 (OMIM: 604969) src kinase-associated phospho (359 aa) initn: 1001 init1: 505 opt: 995 Z-score: 655.2 bits: 129.8 E(85289): 9.3e-30 Smith-Waterman score: 995; 44.6% identity (69.8% similar) in 361 aa overlap (13-359:6-356) 10 20 30 40 50 60 pF1KE0 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYL :::::: :: :.: :.:. :..:::: :...:. ... ....:. : NP_003 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYY 10 20 30 40 50 70 80 90 100 110 pF1KE0 QEFQDKGDAEDGEEYDDPFAGPPDTISLASER---YDKDDEAPSDGAQFPPIAAQDLPFV .:: .: . :: .: .::.:. : .::. : .. .::.: : NP_003 WDFQPQGGDIGQDSSDDNHSGTLG-LSLTSDAPFLSDYQDEGMEDIVK----GAQELDNV 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 LKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTL .: :::::. :::::.: :::::::..:. .::::...:.:: :: : : ::.::: : NP_003 IKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 RKDGKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIP----EDYDER :.:.::. :::... :.: :.:::.:: .:..::.:..:.:.:. : :: :. .:. NP_003 RRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEK 170 180 190 200 210 220 240 250 260 270 280 pF1KE0 GELYDDVDHPLPISNPLTSSQ------PIDDEIYEELPE-EEEDSAPVKVEEQRKMSQDS : :::.: ...: .:: : . : : : :::: : .:.. . .: NP_003 EETYDDID---GFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEED- 230 240 250 260 270 280 290 300 310 320 330 340 pF1KE0 VHHTSGDKSTDYANFYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIG . . :..:::..::::::: : :::::.:::.: ::::::: :::::::... .: NP_003 -ESGTRRKGVDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVG 290 300 310 320 330 340 350 pF1KE0 LVPKAYIMEMYDI .::: :. ... NP_003 IVPKEYLTTAFEVEER 350 >>NP_001068567 (OMIM: 604969) src kinase-associated phos (358 aa) initn: 1022 init1: 505 opt: 992 Z-score: 653.3 bits: 129.4 E(85289): 1.2e-29 Smith-Waterman score: 992; 44.3% identity (69.8% similar) in 361 aa overlap (13-359:6-355) 10 20 30 40 50 60 pF1KE0 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYL :::::: :: :.: :.:. :..:::: :...:. ... ....:. : NP_001 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYY 10 20 30 40 50 70 80 90 100 110 pF1KE0 QEFQDKGDAEDGEEYDDPFAGPPDTISLASER---YDKDDEAPSDGAQFPPIAAQDLPFV .:: .: . :: .: .::.:. : .::. : .. .::.: : NP_001 WDFQPQGGDIGQDSSDDNHSGTLG-LSLTSDAPFLSDYQDEGMEDIVK----GAQELDNV 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 LKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTL .: :::::. :::::.: :::::::..:. .::::...:.:: :: : : ::.::: : NP_001 IKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 RKDGKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIP----EDYDER :.:.::. :::... :.: :.:::.:: .:..::.:..:.:.:. : :: :. .:. NP_001 RRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEK 170 180 190 200 210 220 240 250 260 270 280 pF1KE0 GELYDDVDHPLPISNPLTSSQ------PIDDEIYEELPE-EEEDSAPVKVEEQRKMSQDS : :::.: ...: .:: : . : : : :::: : .:.. . .: NP_001 EETYDDID---GFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEED- 230 240 250 260 270 280 290 300 310 320 330 340 pF1KE0 VHHTSGDKSTDYANFYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIG ... .. :::..::::::: : :::::.:::.: ::::::: :::::::... .: NP_001 --ESGTRRKGDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVG 290 300 310 320 330 340 350 pF1KE0 LVPKAYIMEMYDI .::: :. ... NP_001 IVPKEYLTTAFEVEER 350 >>XP_016880746 (OMIM: 604969) PREDICTED: src kinase-asso (335 aa) initn: 844 init1: 505 opt: 851 Z-score: 564.4 bits: 112.9 E(85289): 1.1e-24 Smith-Waterman score: 851; 43.6% identity (69.0% similar) in 319 aa overlap (56-359:23-332) 30 40 50 60 70 80 pF1KE0 TFVADILKGENLSKKAKEKRESLIKKIKDVKSIYLQEF-QDKGDAEDGEEYDDPFAGPPD ..:. : ..: .. :.. .: . XP_016 MLKSFWQKVCGMRTSALLQGITETIFYGAFSKSKPGGDIGQDSSDDNHSGTL 10 20 30 40 50 90 100 110 120 130 140 pF1KE0 TISLASER---YDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDHSFLGFEWQKRW .::.:. : .::. : .. .::.: :.: :::::. :::::.: :::::: XP_016 GLSLTSDAPFLSDYQDEGMEDIVK----GAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW 60 70 80 90 100 150 160 170 180 190 200 pF1KE0 CALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEISAPDKRIYQFTA :..:. .::::...:.:: :: : : ::.::: ::.:.::. :::... :.: :.::: XP_016 CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTA 110 120 130 140 150 160 210 220 230 240 250 pF1KE0 ASPKDAEEWVQQLKFVLQDMESDIIP----EDYDERGELYDDVDHPLPISNPLTSSQ--- .:: .:..::.:..:.:.:. : :: :. .:. : :::.: ...: .:: XP_016 TSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDG---FDSPSCGSQCRP 170 180 190 200 210 220 260 270 280 290 300 310 pF1KE0 ---PIDDEIYEELPE-EEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYANFYQGLWDCTG : . : : : :::: : .:.. . .: . . :..:::..::::::: : XP_016 TILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEED--ESGTRRKGVDYASYYQGLWDCHG 230 240 250 260 270 280 320 330 340 350 pF1KE0 AFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI :::::.:::.: ::::::: :::::::... .:.::: :. ... XP_016 DQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 290 300 310 320 330 >>XP_016880749 (OMIM: 604969) PREDICTED: src kinase-asso (265 aa) initn: 844 init1: 505 opt: 839 Z-score: 557.9 bits: 111.4 E(85289): 2.5e-24 Smith-Waterman score: 839; 48.8% identity (72.7% similar) in 260 aa overlap (111-359:8-262) 90 100 110 120 130 140 pF1KE0 GPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDHSFLGFEWQKR ::.: :.: :::::. :::::.: ::::: XP_016 MEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKR 10 20 30 150 160 170 180 190 200 pF1KE0 WCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEISAPDKRIYQFT ::..:. .::::...:.:: :: : : ::.::: ::.:.::. :::... :.: :.:: XP_016 WCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFT 40 50 60 70 80 90 210 220 230 240 250 pF1KE0 AASPKDAEEWVQQLKFVLQDMESDIIP----EDYDERGELYDDVDHPLPISNPLTSSQ-- :.:: .:..::.:..:.:.:. : :: :. .:. : :::.: ...: .:: XP_016 ATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDG---FDSPSCGSQCR 100 110 120 130 140 150 260 270 280 290 300 pF1KE0 ----PIDDEIYEELPE-EEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYANFYQGLWDCT : . : : : :::: : .:.. . .: . . :..:::..::::::: XP_016 PTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEED--ESGTRRKGVDYASYYQGLWDCH 160 170 180 190 200 210 310 320 330 340 350 pF1KE0 GAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI : :::::.:::.: ::::::: :::::::... .:.::: :. ... XP_016 GDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 220 230 240 250 260 >>XP_016880748 (OMIM: 604969) PREDICTED: src kinase-asso (265 aa) initn: 844 init1: 505 opt: 839 Z-score: 557.9 bits: 111.4 E(85289): 2.5e-24 Smith-Waterman score: 839; 48.8% identity (72.7% similar) in 260 aa overlap (111-359:8-262) 90 100 110 120 130 140 pF1KE0 GPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDHSFLGFEWQKR ::.: :.: :::::. :::::.: ::::: XP_016 MEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKR 10 20 30 150 160 170 180 190 200 pF1KE0 WCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEISAPDKRIYQFT ::..:. .::::...:.:: :: : : ::.::: ::.:.::. :::... :.: :.:: XP_016 WCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFT 40 50 60 70 80 90 210 220 230 240 250 pF1KE0 AASPKDAEEWVQQLKFVLQDMESDIIP----EDYDERGELYDDVDHPLPISNPLTSSQ-- :.:: .:..::.:..:.:.:. : :: :. .:. : :::.: ...: .:: XP_016 ATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDG---FDSPSCGSQCR 100 110 120 130 140 150 260 270 280 290 300 pF1KE0 ----PIDDEIYEELPE-EEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYANFYQGLWDCT : . : : : :::: : .:.. . .: . . :..:::..::::::: XP_016 PTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEED--ESGTRRKGVDYASYYQGLWDCH 160 170 180 190 200 210 310 320 330 340 350 pF1KE0 GAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI : :::::.:::.: ::::::: :::::::... .:.::: :. ... XP_016 GDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 220 230 240 250 260 >>XP_016880747 (OMIM: 604969) PREDICTED: src kinase-asso (270 aa) initn: 844 init1: 505 opt: 839 Z-score: 557.8 bits: 111.4 E(85289): 2.5e-24 Smith-Waterman score: 839; 48.8% identity (72.7% similar) in 260 aa overlap (111-359:13-267) 90 100 110 120 130 140 pF1KE0 GPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDHSFLGFEWQKR ::.: :.: :::::. :::::.: ::::: XP_016 MKLEGMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKR 10 20 30 40 150 160 170 180 190 200 pF1KE0 WCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEISAPDKRIYQFT ::..:. .::::...:.:: :: : : ::.::: ::.:.::. :::... :.: :.:: XP_016 WCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFT 50 60 70 80 90 100 210 220 230 240 250 pF1KE0 AASPKDAEEWVQQLKFVLQDMESDIIP----EDYDERGELYDDVDHPLPISNPLTSSQ-- :.:: .:..::.:..:.:.:. : :: :. .:. : :::.: ...: .:: XP_016 ATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDG---FDSPSCGSQCR 110 120 130 140 150 260 270 280 290 300 pF1KE0 ----PIDDEIYEELPE-EEEDSAPVKVEEQRKMSQDSVHHTSGDKSTDYANFYQGLWDCT : . : : : :::: : .:.. . .: . . :..:::..::::::: XP_016 PTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEED--ESGTRRKGVDYASYYQGLWDCH 160 170 180 190 200 210 310 320 330 340 350 pF1KE0 GAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI : :::::.:::.: ::::::: :::::::... .:.::: :. ... XP_016 GDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 220 230 240 250 260 270 >>XP_005257812 (OMIM: 604969) PREDICTED: src kinase-asso (341 aa) initn: 956 init1: 505 opt: 691 Z-score: 462.9 bits: 94.1 E(85289): 4.8e-19 Smith-Waterman score: 955; 43.5% identity (68.9% similar) in 354 aa overlap (13-359:6-338) 10 20 30 40 50 60 pF1KE0 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYL :::::: :: :.: :.:. :..:::: :...:. ... ....:. : XP_005 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYY 10 20 30 40 50 70 80 90 100 110 pF1KE0 QEFQDKGDAEDGEEYDDPFAGPPDTISLASER---YDKDDEAPSDGAQFPPIAAQDLPFV .:: .: . :: .: .::.:. : .::. : .. .::.: : XP_005 WDFQPQGGDIGQDSSDDNHSGTLG-LSLTSDAPFLSDYQDEGMEDIVK----GAQELDNV 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 LKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTL .: :::::. :::::.: :::::::..:. .::::...:.:: :: : : ::.::: : XP_005 IKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 RKDGKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIP----EDYDER :.:.::. :::... :.: :.:::.:: .:..::.:..:.:.:. : :: :. .:. XP_005 RRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEK 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 GELYDDVDHPLPISNPLTSSQPIDDEIYEELPEEEEDSAPVKVEEQRKMSQDSVHHTSGD : :::.: ...: .:: : :. .: ..: .: .... XP_005 EETYDDID---GFDSPSCGSQ--------CRPTILPGSVGIKEPTEEKEEED-IYEVL-- 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 KSTDYANFYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYI :::..::::::: : :::::.:::.: ::::::: :::::::... .:.::: :. XP_005 --PDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 280 290 300 310 320 330 pF1KE0 MEMYDI ... XP_005 TTAFEVEER 340 359 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:17:29 2016 done: Sat Nov 5 04:17:30 2016 Total Scan time: 7.750 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]