Result of FASTA (omim) for
pF1KE0606
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0606, 453 aa
1>>>pF1KE0606 453 - 453 aa - 453 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7413+/-0.000453; mu= 21.2598+/- 0.029
mean_var=141.4374+/-40.802, 0's: 0 Z-trim(110.8): 426 B-trim: 1095 in 1/49
Lambda= 0.107843
statistics sampled from 18615 (19265) to 18615 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.226), width: 16
Scan time: 8.290
The best scores are: opt bits E(85289)
NP_001499 (OMIM: 602886) G-protein coupled recepto ( 453) 2983 476.9 4.8e-134
XP_011509323 (OMIM: 602886) PREDICTED: G-protein c ( 293) 1892 306.9 4.8e-83
XP_011527129 (OMIM: 162651) PREDICTED: neurotensin ( 336) 408 76.1 1.6e-13
NP_002522 (OMIM: 162651) neurotensin receptor type ( 418) 408 76.2 1.8e-13
NP_036476 (OMIM: 605538) neurotensin receptor type ( 410) 336 65.0 4.3e-10
XP_005246213 (OMIM: 605538) PREDICTED: neurotensin ( 250) 331 63.9 5.7e-10
XP_006711940 (OMIM: 605538) PREDICTED: neurotensin ( 319) 331 64.1 6.4e-10
XP_006711939 (OMIM: 605538) PREDICTED: neurotensin ( 322) 331 64.1 6.4e-10
XP_016859227 (OMIM: 605538) PREDICTED: neurotensin ( 339) 331 64.1 6.6e-10
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 317 62.1 3.5e-09
NP_001498 (OMIM: 602885) motilin receptor [Homo sa ( 412) 314 61.6 4.6e-09
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 311 61.2 6.6e-09
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 299 59.1 2e-08
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 299 59.3 2.3e-08
XP_011508790 (OMIM: 604153) PREDICTED: neuromedin- ( 376) 292 58.1 4.7e-08
XP_011508791 (OMIM: 604153) PREDICTED: neuromedin- ( 313) 285 56.9 9.1e-08
XP_006712259 (OMIM: 604153) PREDICTED: neuromedin- ( 333) 285 56.9 9.4e-08
XP_006712258 (OMIM: 604153) PREDICTED: neuromedin- ( 370) 285 57.0 9.9e-08
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 285 57.1 1e-07
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 285 57.1 1.1e-07
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 281 56.2 1.3e-07
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 281 56.4 1.5e-07
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 260 53.2 1.6e-06
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 260 53.2 1.6e-06
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 260 53.2 1.6e-06
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446) 248 51.4 5.9e-06
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 229 48.3 4.3e-05
NP_003292 (OMIM: 188545) thyrotropin-releasing hor ( 398) 228 48.2 4.8e-05
XP_011515565 (OMIM: 188545) PREDICTED: thyrotropin ( 398) 228 48.2 4.8e-05
NP_000612 (OMIM: 103780,164230,181500,182135,60678 ( 471) 222 47.4 0.0001
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 214 46.0 0.00022
NP_000789 (OMIM: 126453,143465,606798) D(1B) dopam ( 477) 213 46.0 0.00027
NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 210 45.3 0.00031
NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 210 45.3 0.00031
NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 210 45.3 0.00031
NP_001307846 (OMIM: 118496) muscarinic acetylcholi ( 532) 209 45.4 0.00043
NP_036257 (OMIM: 118496) muscarinic acetylcholine ( 532) 209 45.4 0.00043
XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 203 44.2 0.00068
NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 203 44.2 0.00068
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572) 205 44.9 0.00069
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 203 44.3 0.0007
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 203 44.4 0.00078
NP_000698 (OMIM: 600264) vasopressin V1b receptor ( 424) 202 44.2 0.00082
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 201 43.9 0.00085
NP_057652 (OMIM: 609445) relaxin-3 receptor 1 [Hom ( 469) 201 44.1 0.00096
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 200 43.9 0.001
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 200 43.9 0.001
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 200 43.9 0.001
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 200 43.9 0.001
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 200 43.9 0.001
>>NP_001499 (OMIM: 602886) G-protein coupled receptor 39 (453 aa)
initn: 2983 init1: 2983 opt: 2983 Z-score: 2527.6 bits: 476.9 E(85289): 4.8e-134
Smith-Waterman score: 2983; 100.0% identity (100.0% similar) in 453 aa overlap (1-453:1-453)
10 20 30 40 50 60
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ
370 380 390 400 410 420
430 440 450
pF1KE0 SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
:::::::::::::::::::::::::::::::::
NP_001 SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
430 440 450
>>XP_011509323 (OMIM: 602886) PREDICTED: G-protein coupl (293 aa)
initn: 1892 init1: 1892 opt: 1892 Z-score: 1612.0 bits: 306.9 E(85289): 4.8e-83
Smith-Waterman score: 1892; 99.7% identity (100.0% similar) in 287 aa overlap (1-287:1-287)
10 20 30 40 50 60
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ
:::::::::::::::::::::::::::::::::::::::::::::.:
XP_011 MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLKLPEVIKH
250 260 270 280 290
310 320 330 340 350 360
pF1KE0 IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC
>>XP_011527129 (OMIM: 162651) PREDICTED: neurotensin rec (336 aa)
initn: 486 init1: 395 opt: 408 Z-score: 363.6 bits: 76.1 E(85289): 1.6e-13
Smith-Waterman score: 506; 32.6% identity (63.5% similar) in 301 aa overlap (22-315:53-335)
10 20 30 40
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWI--KITLILVYLIIFVMGLLGNS
:..: : : :. . ::: .::.: .::.
XP_011 QAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNT
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE0 ATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCK
.: . .. ::. : :. ::: ::.:..:..::.:.:..:: . .:.
XP_011 VTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCR
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE0 LHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALP
. :: .::.::: :.: .:: :::.::::::. :.. . ..: .:. .:..:::.:.:
XP_011 GYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVP
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE0 LLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFV
.::.:: . .. ::.: . : : :..... :.: . : .:.
XP_011 MLFTMGEQNRSADGQHAGGLVC--TPTIH-----TATVKV---------VIQVNTFMSFI
210 220 230 240
230 240 250 260 270 280
pF1KE0 VYLVVLLSVAFMCWNMMQVLMK--SQKGSL--AGGTRPPQLRKSESEESRT-ARRQTIIF
.::. . . : . :... ...:.. .:: . . . : .:. : :. .
XP_011 FPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEH--STFSMAIEPGRVQALRHGVRV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 LRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLY
:: .:....:::.: ..::.: ..::
XP_011 LRAVVIAFVVCWLPYHVRRLMFCYISDEQWTP
310 320 330
350 360 370 380 390 400
pF1KE0 TVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARR
>>NP_002522 (OMIM: 162651) neurotensin receptor type 1 [ (418 aa)
initn: 594 init1: 395 opt: 408 Z-score: 362.7 bits: 76.2 E(85289): 1.8e-13
Smith-Waterman score: 614; 32.9% identity (64.3% similar) in 347 aa overlap (22-361:53-381)
10 20 30 40
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWI--KITLILVYLIIFVMGLLGNS
:..: : : :. . ::: .::.: .::.
NP_002 QAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNT
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE0 ATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCK
.: . .. ::. : :. ::: ::.:..:..::.:.:..:: . .:.
NP_002 VTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCR
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE0 LHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALP
. :: .::.::: :.: .:: :::.::::::. :.. . ..: .:. .:..:::.:.:
NP_002 GYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVP
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE0 LLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFV
.::.:: . .. ::.: . : : :..... :.: . : .:.
NP_002 MLFTMGEQNRSADGQHAGGLVC--TPTIH-----TATVKV---------VIQVNTFMSFI
210 220 230 240
230 240 250 260 270 280
pF1KE0 VYLVVLLSVAFMCWNMMQVLMK--SQKGSL--AGGTRPPQLRKSESEESRT-ARRQTIIF
.::. . . : . :... ...:.. .:: . . . : .:. : :. .
NP_002 FPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEH--STFSMAIEPGRVQALRHGVRV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 LRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLY
:: .:....:::.: ..::.: ..:: . : . ....::.::.:::.::
NP_002 LRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILY
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 TVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARR
.. : .::..:. .: :
NP_002 NLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
370 380 390 400 410
>>NP_036476 (OMIM: 605538) neurotensin receptor type 2 [ (410 aa)
initn: 474 init1: 282 opt: 336 Z-score: 302.3 bits: 65.0 E(85289): 4.3e-10
Smith-Waterman score: 513; 28.2% identity (58.7% similar) in 380 aa overlap (28-385:30-399)
10 20 30 40 50
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVL
: :. . .: .:...: ::. ...: ::
NP_036 METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSVHV--VL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 QKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEAC
. .. .. :..::: . .:..:.:.:.:.::..: :.:. . :. : :
NP_036 KARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEY
.:::.: : :: :: .:.:.:.: ... : ... :... :..: .:::. :: ..
NP_036 AYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PLVNV---PSHRGLTCNRSSTRHHEQPETS-NMSICTNLSSRWTVFQSSIFGAFVVYLVV
: .. : . .:. .: : . :. . : :.: . :. : .:..
NP_036 ELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLN---GVTVSHLLA
180 190 200 210 220 230
240 250 260 270
pF1KE0 LLS---------------VAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARR
: : . .. . . .. .: . :: . .:... .. :. .:
NP_036 LCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGG-QVSLVRHKDVRRIRSLQR
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 QTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVI
.. :: ::: ..::.: . ::.: : :: . : . ..:.::.::..
NP_036 -SVQVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAV
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE0 NPLLYTVSSQQFRRVFVQVLCCRLSLQHANHE-KRLRVHAHSTT--DSARFVQRPLLFAS
.::::.. :..::..:.... :: .: ::: . .: : :.:
NP_036 TPLLYNAVSSSFRKLFLEAVS---SLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE0 RRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
>>XP_005246213 (OMIM: 605538) PREDICTED: neurotensin rec (250 aa)
initn: 302 init1: 282 opt: 331 Z-score: 300.0 bits: 63.9 E(85289): 5.7e-10
Smith-Waterman score: 331; 32.7% identity (66.7% similar) in 153 aa overlap (28-180:30-180)
10 20 30 40 50
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVL
: :. . .: .:...: ::. . .: ::
XP_005 METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHV--VL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 QKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEAC
. .. .. :..::: . .:..:.:.:.:.::..: :.:. . :. : :
XP_005 KARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEY
.:::.: : :: :: .:.:.:.: ... : ... :... :..: .:::. :: ..
XP_005 AYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSV
:
XP_005 ELETADGEPEPASRVCTVLVSRTALQVFIQEPSWSCMSSAGCRTMPAGSCTATYLMTRGL
180 190 200 210 220 230
>>XP_006711940 (OMIM: 605538) PREDICTED: neurotensin rec (319 aa)
initn: 282 init1: 282 opt: 331 Z-score: 299.1 bits: 64.1 E(85289): 6.4e-10
Smith-Waterman score: 344; 27.7% identity (59.8% similar) in 249 aa overlap (28-273:30-260)
10 20 30 40 50
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVL
: :. . .: .:...: ::. . .: ::
XP_006 METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHV--VL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 QKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEAC
. .. .. :..::: . .:..:.:.:.:.::..: :.:. . :. : :
XP_006 KARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEY
.:::.: : :: :: .:.:.:.: ... : ... :... :..: .:::. :: ..
XP_006 AYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWT--VF-QSSIFGAFVVYLVVL
: .. . .:: .. .:: : :: . :: : ... .::. :..
XP_006 ELETADG---------------EPEPAS-RVCTVLVSRTALQVFIQVNVLVSFVLPLALT
180 190 200 210 220
240 250 260 270 280 290
pF1KE0 LSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVC
. . . . .: .. .. . :. :. . :::
XP_006 AFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQEPSWS
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 WMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVF
XP_006 CMSSAGCRTMPAGSCTATYLMTRGLTHCTISTTTSTW
290 300 310
>>XP_006711939 (OMIM: 605538) PREDICTED: neurotensin rec (322 aa)
initn: 282 init1: 282 opt: 331 Z-score: 299.0 bits: 64.1 E(85289): 6.4e-10
Smith-Waterman score: 345; 27.4% identity (57.6% similar) in 288 aa overlap (28-307:30-297)
10 20 30 40 50
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVL
: :. . .: .:...: ::. . .: ::
XP_006 METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHV--VL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 QKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEAC
. .. .. :..::: . .:..:.:.:.:.::..: :.:. . :. : :
XP_006 KARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEY
.:::.: : :: :: .:.:.:.: ... : ... :... :..: .:::. :: ..
XP_006 AYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWT--VF-QSSIFGAFVVYLVVL
: .. . .:: .. .:: : :: . :: : ... .::. :..
XP_006 ELETADG---------------EPEPAS-RVCTVLVSRTALQVFIQVNVLVSFVLPLALT
180 190 200 210 220
240 250 260 270 280 290
pF1KE0 LSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEE---SRTARRQTIIFLRLIVVTL
. . . . .: .. .. . :. :. . ::: : . ..: :.. :.:
XP_006 AFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKT--FIQGGQVSL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 AVCW--MPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQ
: : . : : :
XP_006 EPSWSCMSSAGCRTMPAGSCTATYLMTRGLTHCTISTTTSTW
290 300 310 320
>>XP_016859227 (OMIM: 605538) PREDICTED: neurotensin rec (339 aa)
initn: 282 init1: 282 opt: 331 Z-score: 298.8 bits: 64.1 E(85289): 6.6e-10
Smith-Waterman score: 344; 27.7% identity (59.8% similar) in 249 aa overlap (28-273:30-260)
10 20 30 40 50
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVL
: :. . .: .:...: ::. . .: ::
XP_016 METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHV--VL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 QKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEAC
. .. .. :..::: . .:..:.:.:.:.::..: :.:. . :. : :
XP_016 KARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEY
.:::.: : :: :: .:.:.:.: ... : ... :... :..: .:::. :: ..
XP_016 AYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWT--VF-QSSIFGAFVVYLVVL
: .. . .:: .. .:: : :: . :: : ... .::. :..
XP_016 ELETADG---------------EPEPAS-RVCTVLVSRTALQVFIQVNVLVSFVLPLALT
180 190 200 210 220
240 250 260 270 280 290
pF1KE0 LSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVC
. . . . .: .. .. . :. :. . :::
XP_016 AFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVR
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 WMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVF
XP_016 HKDVRRIRSLQRSVQEPSWSCMSSAGCRTMPAGSCTATYLMTRGLTHCTISTTTSTW
290 300 310 320 330
>>XP_016866287 (OMIM: 602393) PREDICTED: orexin receptor (461 aa)
initn: 236 init1: 89 opt: 317 Z-score: 285.8 bits: 62.1 E(85289): 3.5e-09
Smith-Waterman score: 324; 21.7% identity (56.3% similar) in 437 aa overlap (16-435:46-453)
10 20 30 40
pF1KE0 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGL
.. : :.: :. :: :.:.::..:
XP_016 SSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYE---WV---LIAGYIIVFVVAL
20 30 40 50 60
50 60 70 80 90 100
pF1KE0 LGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYT
.:: . : .. :. ... .. .:.:. .:.:: . .: ... . : .
XP_016 IGN---VLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPA---TLVVDITETWFFG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 LS-CKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSA
: ::. .: . ...: . ....:. :::::. .:... . ...: .:..:
XP_016 QSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVI--IWIVSC
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 LVALPLLFAM--GTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQS
.. .: ..: .: .: . . .:.. : . . . :: : . . .
XP_016 IIMIPQAIVMECSTVFPGLANKTTLFTVCDE---RWGGEIYPKMYHICFFLVTYMAPLCL
190 200 210 220 230
230 240 250 260 270
pF1KE0 SIFGAFVVYLVVLL-------SVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKS----ES
... . .. . ::. :. .: . . . : .: . : : :
XP_016 MVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPR-----GPGQPTKSRMSAVAAEI
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 EESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSET
.. : :::.: .: ......:.:..: .: .. . :.. .: . ::.
XP_016 KQIR-ARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYA-WFTFSHW
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE0 FFYLSSVINPLLYTVSSQQFRRVFVQVL-CCRLSLQHANHEKRLRVHAHSTTDSARFVQR
. : .:. ::..:. : .::. : .. :: :...: .: :: ......:.: . .
XP_016 LVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHH-RQEDRL-TRGRTSTESRKSLTT
360 370 380 390 400
400 410 420 430 440
pF1KE0 PLLFASRRQSSARRTEKIFLSTFQS--EAEPQSKSQSLSLESLEPNSGAKPANSAAENGF
. : .. .. .:.. :..... :. . :. :.. :.:
XP_016 QI---SNFDNISKLSEQVVLTSISTLPAANGAGPLQNWCLQQGPPSSLPSTWLDV
410 420 430 440 450 460
450
pF1KE0 QEHEV
453 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:11:16 2016 done: Sat Nov 5 18:11:18 2016
Total Scan time: 8.290 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]