FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0608, 359 aa 1>>>pF1KE0608 359 - 359 aa - 359 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2158+/-0.000828; mu= 12.2527+/- 0.050 mean_var=91.2368+/-17.475, 0's: 0 Z-trim(109.6): 57 B-trim: 2 in 1/51 Lambda= 0.134273 statistics sampled from 10971 (11023) to 10971 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.339), width: 16 Scan time: 3.050 The best scores are: opt bits E(32554) CCDS2204.1 CYTIP gene_id:9595|Hs108|chr2 ( 359) 2358 466.7 1.4e-131 CCDS8817.1 GRASP gene_id:160622|Hs108|chr12 ( 395) 542 114.9 1.2e-25 CCDS61124.1 GRASP gene_id:160622|Hs108|chr12 ( 252) 332 74.1 1.4e-13 >>CCDS2204.1 CYTIP gene_id:9595|Hs108|chr2 (359 aa) initn: 2358 init1: 2358 opt: 2358 Z-score: 2476.0 bits: 466.7 E(32554): 1.4e-131 Smith-Waterman score: 2358; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KE0 MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 LTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 HCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 HCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 LKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 SSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSR 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 RNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 RNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF 310 320 330 340 350 >>CCDS8817.1 GRASP gene_id:160622|Hs108|chr12 (395 aa) initn: 667 init1: 349 opt: 542 Z-score: 574.1 bits: 114.9 E(32554): 1.2e-25 Smith-Waterman score: 643; 39.8% identity (68.3% similar) in 334 aa overlap (45-359:71-395) 20 30 40 50 60 70 pF1KE0 LADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQ :: . .:::: :: .. : ..::. .: CCDS88 PPAAAATPGPPADELYAALEDYHPAELYRALAVSGGTLPR-RKGSGF-RWKNLSQSPEQQ 50 60 70 80 90 80 90 100 110 120 130 pF1KE0 RKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANI ::..:.::.::.:::::::.: .... :: :..:...:.:::. ::: ::..:.. CCDS88 RKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASV 100 110 120 130 140 150 140 150 160 170 180 190 pF1KE0 NGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRS ::...::. ....::.:..:::.: .::: :: : ...::::.:: ::::: .:: :::: CCDS88 NGLNVEGIRHREIVDIIKASGNVLRLETLYGTSI-RKAELEARLQYLKQTLYEKWGEYRS 160 170 180 190 200 210 200 210 220 230 240 pF1KE0 LQLQEHRLLHGDAANCPSL-ENMDLDELSLFGP--LPG--P-GPALVDRNRLSSESSCKS :..::.::.:: ... ::. .... . :.: ::: : :: :. .: .. CCDS88 LMVQEQRLVHGLVVKDPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAVPGRP------RG 220 230 240 250 260 270 250 260 270 280 290 pF1KE0 WLSSMTMDSEDG-YQTCVSEDSSRGAF------SRQTS---TDDECFIPKEGDDF-LRRS :..:. :.:: :: :. .: . .. : : : :: CCDS88 GARRARGDADDAVYHTCFFGDSEPPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRS 280 290 300 310 320 330 300 310 320 330 340 350 pF1KE0 SSRRNRSISNTSSGSM-SPLW-EGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEE .: : . .. ..:. . :: :. ... : ::.. : :..::::::::.:..::: CCDS88 ASVRCAGPGGGGGGGAPGALWTEAREQALCGPGLRKTKYRSFRRRLLKFIPGLNRSLEEE 340 350 360 370 380 390 pF1KE0 ESRF ::.. CCDS88 ESQL >>CCDS61124.1 GRASP gene_id:160622|Hs108|chr12 (252 aa) initn: 473 init1: 167 opt: 332 Z-score: 357.2 bits: 74.1 E(32554): 1.4e-13 Smith-Waterman score: 433; 37.5% identity (66.0% similar) in 253 aa overlap (126-359:7-252) 100 110 120 130 140 150 pF1KE0 RPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSG ..::..:..::...::. ....::.:..:: CCDS61 MTLLPSKGGDTIASVNGLNVEGIRHREIVDIIKASG 10 20 30 160 170 180 190 200 210 pF1KE0 NLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSL-E :.: .::: :: : ...::::.:: ::::: .:: :::::..::.::.:: ... ::. . CCDS61 NVLRLETLYGTSI-RKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYD 40 50 60 70 80 90 220 230 240 250 260 pF1KE0 NMDLDELSLFGP--LPG--P-GPALVDRNRLSSESSCKSWLSSMTMDSEDG-YQTCVSED ... . :.: ::: : :: :. .: .. :..:. :.:: : CCDS61 TLESVRSCLYGAGLLPGSLPFGPLLAVPGRP------RGGARRARGDADDAVYHTCFFGD 100 110 120 130 140 270 280 290 300 310 pF1KE0 SSRGAF------SRQTS---TDDECFIPKEGDDF-LRRSSSRRNRSISNTSSGSM-SPLW : :. .: . .. : : : ::.: : . .. ..:. . :: CCDS61 SEPPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALW 150 160 170 180 190 200 320 330 340 350 pF1KE0 -EGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF :. ... : ::.. : :..::::::::.:..:::::.. CCDS61 TEAREQALCGPGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL 210 220 230 240 250 359 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:29:57 2016 done: Wed Nov 2 20:29:58 2016 Total Scan time: 3.050 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]