FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0610, 363 aa 1>>>pF1KE0610 363 - 363 aa - 363 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3683+/-0.000845; mu= 11.6348+/- 0.051 mean_var=86.6999+/-17.208, 0's: 0 Z-trim(108.2): 31 B-trim: 56 in 1/52 Lambda= 0.137742 statistics sampled from 10069 (10090) to 10069 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.31), width: 16 Scan time: 2.770 The best scores are: opt bits E(32554) CCDS7583.1 PLEKHS1 gene_id:79949|Hs108|chr10 ( 363) 2396 485.9 2.3e-137 CCDS53580.1 PLEKHS1 gene_id:79949|Hs108|chr10 ( 465) 2049 417.0 1.6e-116 CCDS53581.1 PLEKHS1 gene_id:79949|Hs108|chr10 ( 366) 1524 312.6 3.4e-85 >>CCDS7583.1 PLEKHS1 gene_id:79949|Hs108|chr10 (363 aa) initn: 2396 init1: 2396 opt: 2396 Z-score: 2579.5 bits: 485.9 E(32554): 2.3e-137 Smith-Waterman score: 2396; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363) 10 20 30 40 50 60 pF1KE0 MEPKPQKSPGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MEPKPQKSPGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 YYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIET 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 DGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LSPADVEAQTTNDQKGSASLTVVQLSILINNIPDESQVEKLNVFLSPPDVINYLALTEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LSPADVEAQTTNDQKGSASLTVVQLSILINNIPDESQVEKLNVFLSPPDVINYLALTEAT 310 320 330 340 350 360 pF1KE0 GRI ::: CCDS75 GRI >>CCDS53580.1 PLEKHS1 gene_id:79949|Hs108|chr10 (465 aa) initn: 2071 init1: 2047 opt: 2049 Z-score: 2205.2 bits: 417.0 E(32554): 1.6e-116 Smith-Waterman score: 2217; 96.0% identity (96.0% similar) in 354 aa overlap (10-363:4-343) 10 20 30 40 50 60 pF1KE0 MEPKPQKSPGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLS ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MAGGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 YYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 EKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 LQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIET 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 DGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWC 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 LSPADVEAQTTNDQKGSASLTVVQLSILINNIPDESQVEKLNVFLSPPDVINYLALTEAT :::::::::::::::: :::::::::::::::::::::::::::::: CCDS53 LSPADVEAQTTNDQKG--------------NIPDESQVEKLNVFLSPPDVINYLALTEAT 300 310 320 330 340 pF1KE0 GRI ::: CCDS53 GRICVSQWEGPPRLGCIFCHGDHLLAVNDLKPQSLEEVSLFLTRSIQKEDSFRILSYQVA 350 360 370 380 390 400 >>CCDS53581.1 PLEKHS1 gene_id:79949|Hs108|chr10 (366 aa) initn: 1546 init1: 1522 opt: 1524 Z-score: 1643.0 bits: 312.6 E(32554): 3.4e-85 Smith-Waterman score: 1692; 94.9% identity (94.9% similar) in 275 aa overlap (89-363:1-261) 60 70 80 90 100 110 pF1KE0 LSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGH :::::::::::::::::::::::::::::: CCDS53 MQSVQKMFKCHPDEVMSIRTTNREYFLIGH 10 20 30 120 130 140 150 160 170 pF1KE0 DREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPR 40 50 60 70 80 90 180 190 200 210 220 230 pF1KE0 NGLQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NGLQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESI 100 110 120 130 140 150 240 250 260 270 280 290 pF1KE0 ETDGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ETDGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGID 160 170 180 190 200 210 300 310 320 330 340 350 pF1KE0 WCLSPADVEAQTTNDQKGSASLTVVQLSILINNIPDESQVEKLNVFLSPPDVINYLALTE :::::::::::::::::: :::::::::::::::::::::::::::: CCDS53 WCLSPADVEAQTTNDQKG--------------NIPDESQVEKLNVFLSPPDVINYLALTE 220 230 240 250 360 pF1KE0 ATGRI ::::: CCDS53 ATGRICVSQWEGPPRLGCIFCHGDHLLAVNDLKPQSLEEVSLFLTRSIQKEKLKLTIGRI 260 270 280 290 300 310 363 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:27:48 2016 done: Wed Nov 2 20:27:48 2016 Total Scan time: 2.770 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]