Result of FASTA (omim) for
pF1KE0615
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0615, 174 aa
1>>>pF1KE0615 174 - 174 aa - 174 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2119+/-0.000297; mu= 15.2857+/- 0.019
mean_var=158.6106+/-36.706, 0's: 0 Z-trim(119.9): 241 B-trim: 1988 in 1/55
Lambda= 0.101838
statistics sampled from 34007 (34460) to 34007 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.404), width: 16
Scan time: 5.810
The best scores are: opt bits E(85289)
NP_005096 (OMIM: 274000,605313) RNA-binding protei ( 174) 1194 186.3 2.2e-47
NP_001164408 (OMIM: 137070,608030,614782) RNA-bind ( 522) 198 40.7 0.0044
XP_011544083 (OMIM: 137070,608030,614782) PREDICTE ( 524) 198 40.7 0.0045
NP_001164105 (OMIM: 137070,608030,614782) RNA-bind ( 525) 198 40.7 0.0045
NP_004951 (OMIM: 137070,608030,614782) RNA-binding ( 526) 198 40.7 0.0045
NP_001293138 (OMIM: 300907) cleavage stimulation f ( 560) 195 40.3 0.0063
NP_001316 (OMIM: 300907) cleavage stimulation fact ( 577) 195 40.3 0.0064
NP_001293135 (OMIM: 300907) cleavage stimulation f ( 597) 195 40.3 0.0065
NP_056050 (OMIM: 611968) cleavage stimulation fact ( 616) 195 40.3 0.0066
>>NP_005096 (OMIM: 274000,605313) RNA-binding protein 8A (174 aa)
initn: 1194 init1: 1194 opt: 1194 Z-score: 971.6 bits: 186.3 E(85289): 2.2e-47
Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 174 aa overlap (1-174:1-174)
10 20 30 40 50 60
pF1KE0 MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVE
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 YETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSPDRRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSPDRRRR
130 140 150 160 170
>>NP_001164408 (OMIM: 137070,608030,614782) RNA-binding (522 aa)
initn: 166 init1: 116 opt: 198 Z-score: 176.2 bits: 40.7 E(85289): 0.0044
Smith-Waterman score: 198; 30.6% identity (55.3% similar) in 170 aa overlap (11-165:224-384)
10 20 30 40
pF1KE0 MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGF
:: . . : : . .. : :::
NP_001 DQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP----RGRGGGRGGRGG
200 210 220 230 240
50 60 70 80 90
pF1KE0 --GSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGE
::..:. .. : : . . . : . .. .:: :. :..: :.. : : . :
NP_001 MGGSDRGGFNKFGGPRD---QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGI
250 260 270 280 290 300
100 110 120 130 140
pF1KE0 IKN--------IHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWC-
::. :.: ::.:: ::: . : .. :.::.. ..:... :.::.:..
NP_001 IKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT
310 320 330 340 350 360
150 160 170
pF1KE0 ----FVRGPPKGKRRGGRRRSRSPDRRRR
: :: .: :::: :
NP_001 RRADFNRGGGNG--RGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKC
370 380 390 400 410 420
>>XP_011544083 (OMIM: 137070,608030,614782) PREDICTED: R (524 aa)
initn: 166 init1: 116 opt: 198 Z-score: 176.2 bits: 40.7 E(85289): 0.0045
Smith-Waterman score: 198; 30.6% identity (55.3% similar) in 170 aa overlap (11-165:226-386)
10 20 30 40
pF1KE0 MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGF
:: . . : : . .. : :::
XP_011 DQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP----RGRGGGRGGRGG
200 210 220 230 240 250
50 60 70 80 90
pF1KE0 --GSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGE
::..:. .. : : . . . : . .. .:: :. :..: :.. : : . :
XP_011 MGGSDRGGFNKFGGPRD---QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGI
260 270 280 290 300
100 110 120 130 140
pF1KE0 IKN--------IHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWC-
::. :.: ::.:: ::: . : .. :.::.. ..:... :.::.:..
XP_011 IKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT
310 320 330 340 350 360
150 160 170
pF1KE0 ----FVRGPPKGKRRGGRRRSRSPDRRRR
: :: .: :::: :
XP_011 RRADFNRGGGNG--RGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKC
370 380 390 400 410 420
>>NP_001164105 (OMIM: 137070,608030,614782) RNA-binding (525 aa)
initn: 166 init1: 116 opt: 198 Z-score: 176.2 bits: 40.7 E(85289): 0.0045
Smith-Waterman score: 198; 30.6% identity (55.3% similar) in 170 aa overlap (11-165:227-387)
10 20 30 40
pF1KE0 MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGF
:: . . : : . .. : :::
NP_001 DQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP----RGRGGGRGGRGG
200 210 220 230 240 250
50 60 70 80 90
pF1KE0 --GSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGE
::..:. .. : : . . . : . .. .:: :. :..: :.. : : . :
NP_001 MGGSDRGGFNKFGGPRD---QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGI
260 270 280 290 300
100 110 120 130 140
pF1KE0 IKN--------IHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWC-
::. :.: ::.:: ::: . : .. :.::.. ..:... :.::.:..
NP_001 IKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT
310 320 330 340 350 360
150 160 170
pF1KE0 ----FVRGPPKGKRRGGRRRSRSPDRRRR
: :: .: :::: :
NP_001 RRADFNRGGGNG--RGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKC
370 380 390 400 410 420
>>NP_004951 (OMIM: 137070,608030,614782) RNA-binding pro (526 aa)
initn: 166 init1: 116 opt: 198 Z-score: 176.2 bits: 40.7 E(85289): 0.0045
Smith-Waterman score: 198; 30.6% identity (55.3% similar) in 170 aa overlap (11-165:228-388)
10 20 30 40
pF1KE0 MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGF
:: . . : : . .. : :::
NP_004 DQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP----RGRGGGRGGRGG
200 210 220 230 240 250
50 60 70 80 90
pF1KE0 --GSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGE
::..:. .. : : . . . : . .. .:: :. :..: :.. : : . :
NP_004 MGGSDRGGFNKFGGPRD---QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGI
260 270 280 290 300 310
100 110 120 130 140
pF1KE0 IKN--------IHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWC-
::. :.: ::.:: ::: . : .. :.::.. ..:... :.::.:..
NP_004 IKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT
320 330 340 350 360 370
150 160 170
pF1KE0 ----FVRGPPKGKRRGGRRRSRSPDRRRR
: :: .: :::: :
NP_004 RRADFNRGGGNG--RGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKC
380 390 400 410 420
>>NP_001293138 (OMIM: 300907) cleavage stimulation facto (560 aa)
initn: 226 init1: 187 opt: 195 Z-score: 173.6 bits: 40.3 E(85289): 0.0063
Smith-Waterman score: 195; 38.8% identity (72.9% similar) in 85 aa overlap (63-147:8-90)
40 50 60 70 80 90
pF1KE0 KKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDK
.:. .::... .:: .. :::::...:
NP_001 MAGLTVRDPAVDRSLRS--VFVGNIPYEATEEQLKDI
10 20 30
100 110 120 130 140 150
pF1KE0 FAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVR
:.: : . ...: ::.:: ::: . ::. . : .::..:::... :. . ::
NP_001 FSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASE
40 50 60 70 80 90
160 170
pF1KE0 GPPKGKRRGGRRRSRSPDRRRR
NP_001 KNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSP
100 110 120 130 140 150
>>NP_001316 (OMIM: 300907) cleavage stimulation factor s (577 aa)
initn: 226 init1: 187 opt: 195 Z-score: 173.5 bits: 40.3 E(85289): 0.0064
Smith-Waterman score: 195; 38.8% identity (72.9% similar) in 85 aa overlap (63-147:8-90)
40 50 60 70 80 90
pF1KE0 KKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDK
.:. .::... .:: .. :::::...:
NP_001 MAGLTVRDPAVDRSLRS--VFVGNIPYEATEEQLKDI
10 20 30
100 110 120 130 140 150
pF1KE0 FAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVR
:.: : . ...: ::.:: ::: . ::. . : .::..:::... :. . ::
NP_001 FSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASE
40 50 60 70 80 90
160 170
pF1KE0 GPPKGKRRGGRRRSRSPDRRRR
NP_001 KNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSP
100 110 120 130 140 150
>>NP_001293135 (OMIM: 300907) cleavage stimulation facto (597 aa)
initn: 226 init1: 187 opt: 195 Z-score: 173.3 bits: 40.3 E(85289): 0.0065
Smith-Waterman score: 195; 38.8% identity (72.9% similar) in 85 aa overlap (63-147:8-90)
40 50 60 70 80 90
pF1KE0 KKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDK
.:. .::... .:: .. :::::...:
NP_001 MAGLTVRDPAVDRSLRS--VFVGNIPYEATEEQLKDI
10 20 30
100 110 120 130 140 150
pF1KE0 FAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVR
:.: : . ...: ::.:: ::: . ::. . : .::..:::... :. . ::
NP_001 FSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASE
40 50 60 70 80 90
160 170
pF1KE0 GPPKGKRRGGRRRSRSPDRRRR
NP_001 KNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSP
100 110 120 130 140 150
>>NP_056050 (OMIM: 611968) cleavage stimulation factor s (616 aa)
initn: 217 init1: 187 opt: 195 Z-score: 173.2 bits: 40.3 E(85289): 0.0066
Smith-Waterman score: 195; 38.8% identity (72.9% similar) in 85 aa overlap (63-147:8-90)
40 50 60 70 80 90
pF1KE0 KKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDK
.:. .::... .:: .. :::::...:
NP_056 MSSLAVRDPAMDRSLRS--VFVGNIPYEATEEQLKDI
10 20 30
100 110 120 130 140 150
pF1KE0 FAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVR
:.: : . ...: ::.:: ::: . ::. . : .::..:::... :. . ::
NP_056 FSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASE
40 50 60 70 80 90
160 170
pF1KE0 GPPKGKRRGGRRRSRSPDRRRR
NP_056 KNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSH
100 110 120 130 140 150
174 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:09:51 2016 done: Wed Nov 2 20:09:52 2016
Total Scan time: 5.810 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]