Result of FASTA (omim) for
pF1KE0616
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0616, 316 aa
1>>>pF1KE0616 316 - 316 aa - 316 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4107+/-0.000439; mu= 7.0408+/- 0.027
mean_var=223.0608+/-47.144, 0's: 0 Z-trim(118.5): 139 B-trim: 641 in 1/53
Lambda= 0.085874
statistics sampled from 31386 (31600) to 31386 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.371), width: 16
Scan time: 6.010
The best scores are: opt bits E(85289)
NP_001107579 (OMIM: 605889) PDZ and LIM domain pro ( 316) 2182 283.0 5.3e-76
NP_055291 (OMIM: 605889) PDZ and LIM domain protei ( 364) 1095 148.5 2e-35
NP_001244892 (OMIM: 605889) PDZ and LIM domain pro ( 197) 1020 138.8 8.5e-33
NP_001244891 (OMIM: 605889) PDZ and LIM domain pro ( 276) 1013 138.1 1.9e-32
NP_066272 (OMIM: 605900) PDZ and LIM domain protei ( 329) 610 88.3 2.3e-17
XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM ( 226) 590 85.6 1e-16
XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ ( 252) 547 80.4 4.4e-15
NP_003678 (OMIM: 166710,603422) PDZ and LIM domain ( 330) 547 80.5 5.2e-15
NP_001124499 (OMIM: 166710,603422) PDZ and LIM dom ( 246) 513 76.1 8e-14
NP_976227 (OMIM: 605903) PDZ and LIM domain protei ( 423) 439 67.3 6.5e-11
XP_005269525 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 355 56.7 7.5e-08
NP_001073584 (OMIM: 605906,609452) LIM domain-bind ( 330) 355 56.7 7.5e-08
XP_016871097 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 355 56.7 7.5e-08
NP_001165082 (OMIM: 605906,609452) LIM domain-bind ( 398) 353 56.6 1e-07
XP_011537497 (OMIM: 605906,609452) PREDICTED: LIM ( 398) 353 56.6 1e-07
XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM ( 664) 355 57.1 1.2e-07
NP_009009 (OMIM: 605906,609452) LIM domain-binding ( 727) 355 57.1 1.2e-07
XP_005269521 (OMIM: 605906,609452) PREDICTED: LIM ( 727) 355 57.1 1.2e-07
XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 355 57.1 1.3e-07
XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 355 57.1 1.3e-07
NP_001165081 (OMIM: 605906,609452) LIM domain-bind ( 732) 353 56.9 1.5e-07
XP_011537489 (OMIM: 605906,609452) PREDICTED: LIM ( 748) 353 56.9 1.5e-07
XP_011537488 (OMIM: 605906,609452) PREDICTED: LIM ( 795) 353 56.9 1.6e-07
XP_011537486 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 353 56.9 1.6e-07
XP_011537487 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 353 56.9 1.6e-07
XP_011537493 (OMIM: 605906,609452) PREDICTED: LIM ( 633) 342 55.5 3.5e-07
XP_016871098 (OMIM: 605906,609452) PREDICTED: LIM ( 283) 333 53.9 4.5e-07
NP_001073585 (OMIM: 605906,609452) LIM domain-bind ( 283) 333 53.9 4.5e-07
NP_998801 (OMIM: 605903) PDZ and LIM domain protei ( 222) 330 53.4 5e-07
NP_001073583 (OMIM: 605906,609452) LIM domain-bind ( 617) 333 54.3 7.4e-07
XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM ( 680) 333 54.4 7.9e-07
NP_005442 (OMIM: 605903) PDZ and LIM domain protei ( 457) 330 53.8 7.9e-07
XP_011537491 (OMIM: 605906,609452) PREDICTED: LIM ( 696) 333 54.4 8e-07
NP_001011513 (OMIM: 605904) PDZ and LIM domain pro ( 487) 298 49.9 1.3e-05
XP_006714132 (OMIM: 605904) PREDICTED: PDZ and LIM ( 607) 295 49.6 1.9e-05
XP_006714129 (OMIM: 605904) PREDICTED: PDZ and LIM ( 739) 295 49.7 2.2e-05
NP_001011516 (OMIM: 605904) PDZ and LIM domain pro ( 214) 283 47.6 2.8e-05
NP_001011515 (OMIM: 605904) PDZ and LIM domain pro ( 234) 283 47.6 2.9e-05
NP_932159 (OMIM: 609722) PDZ and LIM domain protei ( 278) 283 47.7 3.3e-05
NP_006448 (OMIM: 605904) PDZ and LIM domain protei ( 596) 287 48.6 3.8e-05
XP_016863146 (OMIM: 605904) PREDICTED: PDZ and LIM ( 602) 287 48.6 3.8e-05
NP_789847 (OMIM: 609722) PDZ and LIM domain protei ( 366) 283 47.9 3.9e-05
XP_005262752 (OMIM: 605904) PREDICTED: PDZ and LIM ( 728) 287 48.7 4.3e-05
XP_005262750 (OMIM: 605904) PREDICTED: PDZ and LIM ( 734) 287 48.7 4.3e-05
NP_001243356 (OMIM: 605904) PDZ and LIM domain pro ( 483) 283 48.0 4.6e-05
XP_005262755 (OMIM: 605904) PREDICTED: PDZ and LIM ( 493) 283 48.0 4.7e-05
XP_016863147 (OMIM: 605904) PREDICTED: PDZ and LIM ( 498) 283 48.0 4.7e-05
XP_011529845 (OMIM: 605904) PREDICTED: PDZ and LIM ( 600) 283 48.1 5.3e-05
NP_067643 (OMIM: 609722) PDZ and LIM domain protei ( 602) 283 48.1 5.3e-05
XP_006714133 (OMIM: 605904) PREDICTED: PDZ and LIM ( 605) 283 48.1 5.3e-05
>>NP_001107579 (OMIM: 605889) PDZ and LIM domain protein (316 aa)
initn: 2182 init1: 2182 opt: 2182 Z-score: 1485.4 bits: 283.0 E(85289): 5.3e-76
Smith-Waterman score: 2182; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR
250 260 270 280 290 300
310
pF1KE0 TKPPEGYDTVTLYPKA
::::::::::::::::
NP_001 TKPPEGYDTVTLYPKA
310
>>NP_055291 (OMIM: 605889) PDZ and LIM domain protein 3 (364 aa)
initn: 1827 init1: 1010 opt: 1095 Z-score: 756.9 bits: 148.5 E(85289): 2e-35
Smith-Waterman score: 1659; 74.4% identity (81.3% similar) in 348 aa overlap (17-316:17-364)
10 20 30 40 50 60
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
::::::::::::::::::::::::::::::::::::::::::::::::::. . . ::
NP_055 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN
70 80 90 100 110 120
130
pF1KE0 RRAQPFV---------AAANID--------------------DKR---------------
: .::: . ..:: : .
NP_055 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE0 ---QVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSP-QNEPTASVPPESDVYRMLHDN
..: :..:.:. ::: .::...:.::. . .: ..:::::::::::::::::::
NP_055 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDN
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE0 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE0 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL
310 320 330 340 350 360
pF1KE0 YPKA
::::
NP_055 YPKA
>>NP_001244892 (OMIM: 605889) PDZ and LIM domain protein (197 aa)
initn: 1249 init1: 1010 opt: 1020 Z-score: 709.8 bits: 138.8 E(85289): 8.5e-33
Smith-Waterman score: 1030; 58.5% identity (60.1% similar) in 316 aa overlap (1-316:1-197)
10 20 30 40 50 60
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
:::::::::::::::::::::::::::::::
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITR-----------------------------
10 20 30
70 80 90 100 110 120
pF1KE0 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
::. : ::
NP_001 ----------------------------------DGNYFEHK----------------HN
40
130 140 150 160 170 180
pF1KE0 RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP
: .::: ::. ..:::::::
NP_001 IRPKPFV---------------------------------------IPGR-SSEPTASVP
50 60
190 200 210 220 230 240
pF1KE0 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA
70 80 90 100 110 120
250 260 270 280 290 300
pF1KE0 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR
130 140 150 160 170 180
310
pF1KE0 TKPPEGYDTVTLYPKA
::::::::::::::::
NP_001 TKPPEGYDTVTLYPKA
190
>>NP_001244891 (OMIM: 605889) PDZ and LIM domain protein (276 aa)
initn: 1788 init1: 1010 opt: 1013 Z-score: 703.4 bits: 138.1 E(85289): 1.9e-32
Smith-Waterman score: 1716; 82.6% identity (84.8% similar) in 316 aa overlap (1-316:1-276)
10 20 30 40 50 60
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
::::::::::::::::::::::::::::::::::::::::::::::::::. . . ::
NP_001 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP
: .::: ::. ..:::::::
NP_001 IRPKPFV---------------------------------------IPGR-SSEPTASVP
130 140
190 200 210 220 230 240
pF1KE0 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR
210 220 230 240 250 260
310
pF1KE0 TKPPEGYDTVTLYPKA
::::::::::::::::
NP_001 TKPPEGYDTVTLYPKA
270
>>NP_066272 (OMIM: 605900) PDZ and LIM domain protein 1 (329 aa)
initn: 1182 init1: 610 opt: 610 Z-score: 432.7 bits: 88.3 E(85289): 2.3e-17
Smith-Waterman score: 1175; 53.4% identity (78.4% similar) in 328 aa overlap (3-315:4-329)
10 20 30 40 50
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTES
: . : ::.:::::: :: ::.:::.:.:.::::::: :::: :::: :::: .: .
NP_066 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 MTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAH
::: .::.:::. . .: : . :.: ..::: :.:.:: ::.:.:: ::::: ::.::
NP_066 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 NRRAQPFVAAANIDDKRQVVSASYNSPIGLYST---SNIQDALHGQL--RGLIPSS-PQN
:: :.::.:. . .:.. .::.: ::::. ::...::... :. .: : .
NP_066 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
130 140 150 160 170 180
180 190 200 210 220
pF1KE0 --EPTAS--VPPESDVYRMLHDNR--NEPTQPRQSGSFRVLQGMVDD---GSDDRPAGTR
.: .: . ::.::.::.... ::: :.:: :: ::: .... :. ..:.: :
NP_066 HAQPPSSLVIDKESEVYKMLQEKQELNEP--PKQSTSFLVLQEILESEEKGDPNKPSGFR
190 200 210 220 230
230 240 250 260 270 280
pF1KE0 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY
::.:::::: .. :.::..:.:::::.::::. :: ::..:::::.::.::. ::::::.
NP_066 SVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGH
240 250 260 270 280 290
290 300 310
pF1KE0 FFIEGELYCETHARARTKPPEGYDTVTLYPKA
::.: ..::: ::: :. :::::..::..::
NP_066 FFVEDQIYCEKHARERVTPPEGYEVVTVFPK
300 310 320
>>XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM dom (226 aa)
initn: 753 init1: 510 opt: 590 Z-score: 421.2 bits: 85.6 E(85289): 1e-16
Smith-Waterman score: 746; 50.0% identity (77.2% similar) in 228 aa overlap (103-315:1-226)
80 90 100 110 120 130
pF1KE0 AHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQPFVAAANI
.:: ::::: ::.:::: :.::.:.
XP_011 MNLASEPQEVLHIGSAHNRSAMPFTASPAS
10 20 30
140 150 160 170 180
pF1KE0 DDKRQVVSASYNSPIGLYST---SNIQDALHGQL--RGLIPSS-PQN--EPTAS--VPPE
. .:.. .::.: ::::. ::...::... :. .: : . .: .: . :
XP_011 STTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKE
40 50 60 70 80 90
190 200 210 220 230
pF1KE0 SDVYRMLHDNR--NEPTQPRQSGSFRVLQGMVDD---GSDDRPAGTRSVRAPVTKVHGGS
:.::.::.... ::: :.:: :: ::: .... :. ..:.: :::.:::::: ..
XP_011 SEVYKMLQEKQELNEP--PKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASI
100 110 120 130 140
240 250 260 270 280 290
pF1KE0 GGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHA
:.::..:.:::::.::::. :: ::..:::::.::.::. ::::::.::.: ..::: ::
XP_011 GNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHA
150 160 170 180 190 200
300 310
pF1KE0 RARTKPPEGYDTVTLYPKA
: :. :::::..::..::
XP_011 RERVTPPEGYEVVTVFPK
210 220
>>XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ and (252 aa)
initn: 626 init1: 383 opt: 547 Z-score: 391.8 bits: 80.4 E(85289): 4.4e-15
Smith-Waterman score: 587; 38.3% identity (57.9% similar) in 321 aa overlap (1-316:1-247)
10 20 30 40 50 60
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
::..: : ::.:::::: :: ::. ::.:.: :: ... :. . : : :.
XP_016 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISR--DGSPTTSRR--PSGT-----GTGPED-
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
:. : :: ..: .: :. ::
XP_016 ----------------------GRPSLGSPY---------------GQPPRF-PV--PHN
60 70
130 140 150 160 170 180
pF1KE0 RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP
.. . : .:. . :: . . : ::: : : . :
XP_016 GSSEATLPAQ--------MSTLHVSP-----PPSADPA-----RGL-PRSRD----CRVD
80 90 100
190 200 210 220 230
pF1KE0 PESDVYRMLHDNRNEPT--QPRQSGSFRVLQGMVD--DGSD-DRPAGTRSVRAPVTKVHG
:.:::::.. ::. .:.:::::: ::::.. .:.: :.: :... ..:. .
XP_016 LGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGA
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE0 GSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCET
.: : .: : .:: ::::..:::::: :::::.:.::.:::::.::::.. .::::.
XP_016 PLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCES
170 180 190 200 210 220
300 310
pF1KE0 HARARTKPPEGYDTVTLYPKA
::.::.:::::::.:..::.:
XP_016 HAKARVKPPEGYDVVAVYPNAKVELV
230 240 250
>>NP_003678 (OMIM: 166710,603422) PDZ and LIM domain pro (330 aa)
initn: 816 init1: 383 opt: 547 Z-score: 390.5 bits: 80.5 E(85289): 5.2e-15
Smith-Waterman score: 934; 44.6% identity (72.3% similar) in 332 aa overlap (1-316:1-325)
10 20 30 40 50 60
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
::..: : ::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: :
NP_003 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
:: .::.:::. .: :...: : . : :.. .:.::. .:... : :. .: . .
NP_003 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSP---TTS
70 80 90 100 110
130 140 150 160 170
pF1KE0 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGL-IPSSPQNEPTA
:: : .... .: : ... :..: . . ... . .: .:. : . :. .:.
NP_003 RR--PSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 SVPPESD--------VYRMLHDNRNEPT--QPRQSGSFRVLQGMVD--DGSD-DRPAGTR
..: : :::::.. ::. .:.:::::: ::::.. .:.: :.: :
NP_003 GLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY
... ..:. . .: : .: : .:: ::::..:::::: :::::.:.::.:::::.::
NP_003 NLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGY
240 250 260 270 280 290
290 300 310
pF1KE0 FFIEGELYCETHARARTKPPEGYDTVTLYPKA
::.. .::::.::.::.:::::::.:..::.:
NP_003 FFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
300 310 320 330
>>NP_001124499 (OMIM: 166710,603422) PDZ and LIM domain (246 aa)
initn: 424 init1: 343 opt: 513 Z-score: 369.2 bits: 76.1 E(85289): 8e-14
Smith-Waterman score: 513; 37.9% identity (66.3% similar) in 243 aa overlap (1-230:1-236)
10 20 30 40 50 60
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
::..: : ::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: :
NP_001 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
:: .::.:::. .: :...: : . : :.. .:.::. .:... : :. .: .
NP_001 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTS---
70 80 90 100 110
130 140 150 160 170
pF1KE0 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGL-IPSSPQNEPTA
:: : .... .: : ... :..: . . ... . .: .:. : . :. .:.
NP_001 RR--PSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 SVPPESD--------VYRMLHDNRNEPT--QPRQSGSFRVLQGMVDDGSDDRPAGTRSVR
..: : :::::.. ::. .:.:::::: ::::.. : :.. ...
NP_001 GLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 APVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFI
. .
NP_001 STIPSASCAVTAA
240
>>NP_976227 (OMIM: 605903) PDZ and LIM domain protein 7 (423 aa)
initn: 468 init1: 314 opt: 439 Z-score: 317.0 bits: 67.3 E(85289): 6.5e-11
Smith-Waterman score: 446; 30.0% identity (56.1% similar) in 310 aa overlap (5-303:6-305)
10 20 30 40 50
pF1KE0 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTES
:.: :::::::::.:: ::: :: :.:.:::.::: :.. :: .:.::: .. :
NP_976 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 MTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPF--------KINLESEPQE
.:: .::..:.: ...: : ..:.. .:: . .:. : : . ..
NP_976 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKVQTPDKQPLRPLVPDASKQRLMENTED
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 FKP-IGTAHNRRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSS
..: ::...: : :.. . . . . . : ..:.. . . :.
NP_976 WRPRPGTGQSR---SFRILAHLTGTEFMQDPDEEH---LKKSSQVPRTEAPAPASSTPQE
130 140 150 160 170
180 190 200 210 220
pF1KE0 PQNEPTASVPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRS--VRA
: ::: : . . : : .... :: . .. : .:. :.:
NP_976 PWPGPTAPSPTSRPPW-AVDPAFAERYAPDKTST--VLTRHSQPATPT-PLQSRTSIVQA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 PVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIE
. : ::... . :.: .: . : : . : . ::: :::..:. :.. :.: .
NP_976 AAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEK
240 250 260 270 280 290
290 300 310
pF1KE0 GELYCETHARARTKPPEGYDTVTLYPKA
: ..: .: :
NP_976 GAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEG
300 310 320 330 340 350
316 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:06:53 2016 done: Wed Nov 2 20:06:54 2016
Total Scan time: 6.010 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]