FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0617, 183 aa 1>>>pF1KE0617 183 - 183 aa - 183 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5484+/-0.000422; mu= 8.3994+/- 0.026 mean_var=227.0842+/-51.259, 0's: 0 Z-trim(117.7): 217 B-trim: 1150 in 1/52 Lambda= 0.085110 statistics sampled from 29763 (30027) to 29763 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.352), width: 16 Scan time: 4.440 The best scores are: opt bits E(85289) NP_006616 (OMIM: 605221) serine/arginine-rich spli ( 183) 1269 168.0 7.8e-42 NP_001177936 (OMIM: 605221) serine/arginine-rich s ( 182) 1252 165.9 3.3e-41 NP_001287866 (OMIM: 605221) serine/arginine-rich s ( 217) 1136 151.7 7.1e-37 NP_473357 (OMIM: 605221) serine/arginine-rich spli ( 262) 1136 151.9 7.9e-37 NP_001177935 (OMIM: 605221) serine/arginine-rich s ( 173) 1126 150.4 1.5e-36 NP_001177934 (OMIM: 605221) serine/arginine-rich s ( 261) 1119 149.8 3.3e-36 NP_001287865 (OMIM: 605221) serine/arginine-rich s ( 172) 1109 148.3 6.2e-36 NP_001177938 (OMIM: 605221) serine/arginine-rich s ( 165) 998 134.6 7.7e-32 XP_016855589 (OMIM: 605221) PREDICTED: serine/argi ( 167) 475 70.4 1.7e-12 XP_016855591 (OMIM: 605221) PREDICTED: serine/argi ( 167) 475 70.4 1.7e-12 XP_016855590 (OMIM: 605221) PREDICTED: serine/argi ( 167) 475 70.4 1.7e-12 XP_016880431 (OMIM: 600813) PREDICTED: serine/argi ( 221) 363 56.8 2.7e-08 NP_003007 (OMIM: 600813) serine/arginine-rich spli ( 221) 363 56.8 2.7e-08 NP_001182356 (OMIM: 600813) serine/arginine-rich s ( 221) 363 56.8 2.7e-08 NP_003008 (OMIM: 603364) serine/arginine-rich spli ( 164) 334 53.1 2.7e-07 NP_115285 (OMIM: 603269) serine/arginine-rich spli ( 282) 317 51.4 1.5e-06 XP_016872631 (OMIM: 603269) PREDICTED: serine/argi ( 282) 317 51.4 1.5e-06 XP_005264542 (OMIM: 600572) PREDICTED: serine/argi ( 223) 308 50.1 2.9e-06 NP_001182375 (OMIM: 600572) serine/arginine-rich s ( 226) 308 50.1 2.9e-06 XP_005264541 (OMIM: 600572) PREDICTED: serine/argi ( 235) 308 50.1 3e-06 NP_001026854 (OMIM: 600572) serine/arginine-rich s ( 238) 308 50.1 3e-06 XP_016862522 (OMIM: 602719) PREDICTED: transformer ( 188) 273 45.7 5.2e-05 XP_005247760 (OMIM: 602719) PREDICTED: transformer ( 188) 273 45.7 5.2e-05 XP_011511374 (OMIM: 602719) PREDICTED: transformer ( 188) 273 45.7 5.2e-05 NP_001230808 (OMIM: 602719) transformer-2 protein ( 188) 273 45.7 5.2e-05 NP_004584 (OMIM: 602719) transformer-2 protein hom ( 288) 273 46.0 6.6e-05 NP_001287744 (OMIM: 602649) cold-inducible RNA-bin ( 168) 247 42.4 0.00044 XP_016881726 (OMIM: 602649) PREDICTED: cold-induci ( 168) 247 42.4 0.00044 NP_001271 (OMIM: 602649) cold-inducible RNA-bindin ( 172) 247 42.4 0.00045 XP_006722700 (OMIM: 602649) PREDICTED: cold-induci ( 172) 247 42.4 0.00045 XP_011525970 (OMIM: 602649) PREDICTED: cold-induci ( 202) 247 42.5 0.00049 NP_001287758 (OMIM: 602649) cold-inducible RNA-bin ( 297) 247 42.8 0.00061 NP_001269688 (OMIM: 602718) transformer-2 protein ( 180) 233 40.7 0.0015 NP_001287998 (OMIM: 180740) U1 small nuclear ribon ( 428) 238 41.9 0.0016 NP_001269686 (OMIM: 602718) transformer-2 protein ( 181) 230 40.4 0.002 XP_005249782 (OMIM: 602718) PREDICTED: transformer ( 181) 230 40.4 0.002 XP_016867579 (OMIM: 602718) PREDICTED: transformer ( 181) 230 40.4 0.002 NP_001269687 (OMIM: 602718) transformer-2 protein ( 181) 230 40.4 0.002 XP_016867578 (OMIM: 602718) PREDICTED: transformer ( 181) 230 40.4 0.002 NP_037425 (OMIM: 602718) transformer-2 protein hom ( 282) 230 40.7 0.0025 >>NP_006616 (OMIM: 605221) serine/arginine-rich splicing (183 aa) initn: 1269 init1: 1269 opt: 1269 Z-score: 872.0 bits: 168.0 E(85289): 7.8e-42 Smith-Waterman score: 1269; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS 130 140 150 160 170 180 pF1KE0 RKI ::: NP_006 RKI >>NP_001177936 (OMIM: 605221) serine/arginine-rich splic (182 aa) initn: 1005 init1: 1005 opt: 1252 Z-score: 860.8 bits: 165.9 E(85289): 3.3e-41 Smith-Waterman score: 1252; 99.5% identity (99.5% similar) in 183 aa overlap (1-183:1-182) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: NP_001 SRSYERRRSRSRSFDYNYRRSYSPRN-RPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS 130 140 150 160 170 pF1KE0 RKI ::: NP_001 RKI 180 >>NP_001287866 (OMIM: 605221) serine/arginine-rich splic (217 aa) initn: 1133 init1: 1133 opt: 1136 Z-score: 783.0 bits: 151.7 E(85289): 7.1e-37 Smith-Waterman score: 1180; 84.2% identity (84.2% similar) in 215 aa overlap (1-181:1-215) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDR---------------- :::::::::::::::::::::::::::::::::::::::::::: NP_001 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSR 130 140 150 160 170 180 170 180 pF1KE0 ------------------PNCSWNTQYSSAYYTSRKI ::::::::::::::::: NP_001 SRSKSQPKKEMKAKSRSRPNCSWNTQYSSAYYTSRKI 190 200 210 >>NP_473357 (OMIM: 605221) serine/arginine-rich splicing (262 aa) initn: 1133 init1: 1133 opt: 1136 Z-score: 782.2 bits: 151.9 E(85289): 7.9e-37 Smith-Waterman score: 1136; 92.8% identity (95.6% similar) in 181 aa overlap (1-181:1-180) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS :::::::::::::::::::::::::::::::::::::::::::: . : ..: . .: NP_473 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFK-HRNRSFSRSKSNS 130 140 150 160 170 pF1KE0 RKI : NP_473 RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQS 180 190 200 210 220 230 >>NP_001177935 (OMIM: 605221) serine/arginine-rich splic (173 aa) initn: 1126 init1: 1126 opt: 1126 Z-score: 777.4 bits: 150.4 E(85289): 1.5e-36 Smith-Waterman score: 1126; 100.0% identity (100.0% similar) in 163 aa overlap (1-163:1-163) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS ::::::::::::::::::::::::::::::::::::::::::: NP_001 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDSQVSKKKNER 130 140 150 160 170 pF1KE0 RKI >>NP_001177934 (OMIM: 605221) serine/arginine-rich splic (261 aa) initn: 1041 init1: 1005 opt: 1119 Z-score: 771.0 bits: 149.8 E(85289): 3.3e-36 Smith-Waterman score: 1119; 92.3% identity (95.0% similar) in 181 aa overlap (1-181:1-179) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS :::::::::::::::::::::::::: ::::::::::::::::: . : ..: . .: NP_001 SRSYERRRSRSRSFDYNYRRSYSPRN-RPTGRPRRSRSHSDNDRFK-HRNRSFSRSKSNS 130 140 150 160 170 pF1KE0 RKI : NP_001 RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQS 180 190 200 210 220 230 >>NP_001287865 (OMIM: 605221) serine/arginine-rich splic (172 aa) initn: 1005 init1: 1005 opt: 1109 Z-score: 766.1 bits: 148.3 E(85289): 6.2e-36 Smith-Waterman score: 1109; 99.4% identity (99.4% similar) in 163 aa overlap (1-163:1-162) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS :::::::::::::::::::::::::: :::::::::::::::: NP_001 SRSYERRRSRSRSFDYNYRRSYSPRN-RPTGRPRRSRSHSDNDSQVSKKKNER 130 140 150 160 170 pF1KE0 RKI >>NP_001177938 (OMIM: 605221) serine/arginine-rich splic (165 aa) initn: 998 init1: 998 opt: 998 Z-score: 692.7 bits: 134.6 E(85289): 7.7e-32 Smith-Waterman score: 1091; 89.6% identity (90.2% similar) in 183 aa overlap (1-183:1-165) 10 20 30 40 50 60 pF1KE0 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTS ::::::::::::::::::::::::: .:::::::::::::::: NP_001 SRSYERRRSRSRSFDYNYRRSYSPR------------------KPNCSWNTQYSSAYYTS 130 140 150 160 pF1KE0 RKI ::: NP_001 RKI >>XP_016855589 (OMIM: 605221) PREDICTED: serine/arginine (167 aa) initn: 472 init1: 472 opt: 475 Z-score: 345.5 bits: 70.4 E(85289): 1.7e-12 Smith-Waterman score: 475; 84.9% identity (90.7% similar) in 86 aa overlap (96-181:1-85) 70 80 90 100 110 120 pF1KE0 DALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYE :::::::::::::::::::::::::::::: XP_016 MKAKEGRNVYSSSRYDDYDRYRRSRSRSYE 10 20 30 130 140 150 160 170 180 pF1KE0 RRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTSRKI ::::::::::::::::::::::::::::::::::::::: . : ..: . .:: XP_016 RRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFK-HRNRSFSRSKSNSRSRSK 40 50 60 70 80 XP_016 SQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSR 90 100 110 120 130 140 >>XP_016855591 (OMIM: 605221) PREDICTED: serine/arginine (167 aa) initn: 472 init1: 472 opt: 475 Z-score: 345.5 bits: 70.4 E(85289): 1.7e-12 Smith-Waterman score: 475; 84.9% identity (90.7% similar) in 86 aa overlap (96-181:1-85) 70 80 90 100 110 120 pF1KE0 DALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYE :::::::::::::::::::::::::::::: XP_016 MKAKEGRNVYSSSRYDDYDRYRRSRSRSYE 10 20 30 130 140 150 160 170 180 pF1KE0 RRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTSRKI ::::::::::::::::::::::::::::::::::::::: . : ..: . .:: XP_016 RRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFK-HRNRSFSRSKSNSRSRSK 40 50 60 70 80 XP_016 SQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSR 90 100 110 120 130 140 183 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:05:49 2016 done: Wed Nov 2 20:05:50 2016 Total Scan time: 4.440 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]