FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0626, 372 aa 1>>>pF1KE0626 372 - 372 aa - 372 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5789+/-0.00108; mu= 10.3772+/- 0.065 mean_var=100.2177+/-19.672, 0's: 0 Z-trim(106.1): 84 B-trim: 53 in 1/49 Lambda= 0.128116 statistics sampled from 8721 (8795) to 8721 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.27), width: 16 Scan time: 2.820 The best scores are: opt bits E(32554) CCDS33485.1 PARD6B gene_id:84612|Hs108|chr20 ( 372) 2421 458.2 5.4e-129 CCDS12022.1 PARD6G gene_id:84552|Hs108|chr18 ( 376) 1331 256.7 2.4e-68 CCDS10843.1 PARD6A gene_id:50855|Hs108|chr16 ( 346) 1096 213.2 2.7e-55 CCDS45514.1 PARD6A gene_id:50855|Hs108|chr16 ( 345) 1085 211.2 1.1e-54 >>CCDS33485.1 PARD6B gene_id:84612|Hs108|chr20 (372 aa) initn: 2421 init1: 2421 opt: 2421 Z-score: 2429.3 bits: 458.2 E(32554): 5.4e-129 Smith-Waterman score: 2421; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372) 10 20 30 40 50 60 pF1KE0 MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 NLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIED 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 NGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQ 310 320 330 340 350 360 370 pF1KE0 KLLEEDGTIITL :::::::::::: CCDS33 KLLEEDGTIITL 370 >>CCDS12022.1 PARD6G gene_id:84552|Hs108|chr18 (376 aa) initn: 1306 init1: 802 opt: 1331 Z-score: 1340.4 bits: 256.7 E(32554): 2.4e-68 Smith-Waterman score: 1331; 64.2% identity (86.4% similar) in 316 aa overlap (1-309:1-314) 10 20 30 40 50 pF1KE0 MNRS-HRHGAGS--GCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVD :::: :. . : ...:::::::::::::::.: ::::::.:: :. :.:.: : : CCDS12 MNRSFHKSQTLRFYDC-SAVEVKSKFGAEFRRFSLDRHKPGKFEDFYKLVVHTHHISNSD 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLT : .::::.::::::::::::. ::::.::::::.::::.:::. ...:. .: ... .: CCDS12 VTIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRAL- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 NVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGS ..:: .. :.. :. :..:.::::::::::::..:::::::::...: :::::::::::. CCDS12 GALRDEGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIA :::::::::::::::::::.::::::.:::::::::::::::::::.::.:::::::::: CCDS12 SVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 NSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNS--LLGYPQ-QIEPSFEPEDEDSEED ::.:::.::.::::::::::..:. :::: .:.. ..: : .. .:.:.. .:.:: CCDS12 NSHNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDED 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 -DIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEF :..:: . : . :. CCDS12 NDVVIEGTLEPARPPQTPGAPAGSLSRVNGAGLAQRLQRDLALDGGLQRLLSSLRADPRH 300 310 320 330 340 350 >>CCDS10843.1 PARD6A gene_id:50855|Hs108|chr16 (346 aa) initn: 1046 init1: 715 opt: 1096 Z-score: 1106.2 bits: 213.2 E(32554): 2.7e-55 Smith-Waterman score: 1111; 57.7% identity (78.5% similar) in 317 aa overlap (1-308:1-303) 10 20 30 40 50 60 pF1KE0 MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLV : : .: : : . .:::::: ::::::.: :.. . :.:: ::. ::.::..:::. CCDS10 MARPQRTPARSPD-SIVEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVHQIPGLDVLL 10 20 30 40 50 70 80 90 100 110 pF1KE0 GYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYS--AFGTDTLIKKKNVLTN ::.: ::::::..:::. :.:.... : ::...::. ::: : ::....: ..:. : CCDS10 GYTDAHGDLLPLTNDDSLHRALASGPPPLRLLVQKRAEADSSGLAFASNSLQRRKKGL-- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 VLRPDNH-RKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGS .::: : .: ..::.::::: :::.::::.::::::::::.:.:...::::::::: CCDS10 LLRPVAPLRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGM 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIA ::::.:.:::.:::::::::: ::::.:::::::.::.::::::::.::.::::::::.: CCDS10 SVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 NSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDII ::.:::.::.:::::::::: :.::. : : : :: : :.. .:.. CCDS10 NSHNLIVTVKPANQRNNVVR-----GASGRLTGPPSAG-PGPAEP-----DSDDDSSDLV 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 IED------NGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNT ::. ::. : : CCDS10 IENRQPPSSNGLSQGPPCWDLHPGCRHPGTRSSLPSLDDQEQASSGWGSRIRGDGSGFSL 290 300 310 320 330 340 >>CCDS45514.1 PARD6A gene_id:50855|Hs108|chr16 (345 aa) initn: 1007 init1: 1007 opt: 1085 Z-score: 1095.3 bits: 211.2 E(32554): 1.1e-54 Smith-Waterman score: 1100; 57.7% identity (78.5% similar) in 317 aa overlap (1-308:1-302) 10 20 30 40 50 60 pF1KE0 MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLV : : .: : : . .:::::: ::::::.: :.. . :.:: ::. ::.::..:::. CCDS45 MARPQRTPARSPD-SIVEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVHQIPGLDVLL 10 20 30 40 50 70 80 90 100 110 pF1KE0 GYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYS--AFGTDTLIKKKNVLTN ::.: ::::::..:::. :.:.... : ::...::.: :: : ::....: ..:. : CCDS45 GYTDAHGDLLPLTNDDSLHRALASGPPPLRLLVQKRE-ADSSGLAFASNSLQRRKKGL-- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 VLRPDNH-RKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGS .::: : .: ..::.::::: :::.::::.::::::::::.:.:...::::::::: CCDS45 LLRPVAPLRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGM 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIA ::::.:.:::.:::::::::: ::::.:::::::.::.::::::::.::.::::::::.: CCDS45 SVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 NSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDII ::.:::.::.:::::::::: :.::. : : : :: : :.. .:.. CCDS45 NSHNLIVTVKPANQRNNVVR-----GASGRLTGPPSAG-PGPAEP-----DSDDDSSDLV 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 IED------NGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNT ::. ::. : : CCDS45 IENRQPPSSNGLSQGPPCWDLHPGCRHPGTRSSLPSLDDQEQASSGWGSRIRGDGSGFSL 290 300 310 320 330 340 372 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:17:37 2016 done: Sat Nov 5 20:17:37 2016 Total Scan time: 2.820 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]