FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0629, 198 aa
  1>>>pF1KE0629 198 - 198 aa - 198 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3799+/-0.000696; mu= 13.2219+/- 0.041
 mean_var=78.2213+/-15.913, 0's: 0 Z-trim(111.0): 62  B-trim: 505 in 1/50
 Lambda= 0.145015
 statistics sampled from 11950 (12015) to 11950 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.369), width:  16
 Scan time:  2.110

The best scores are:                                      opt bits E(32554)
CCDS9047.1 SOCS2 gene_id:8835|Hs108|chr12          ( 198) 1338 288.7 1.5e-78
CCDS2831.1 CISH gene_id:1154|Hs108|chr3            ( 258)  397 92.0 3.5e-19
CCDS46834.1 CISH gene_id:1154|Hs108|chr3           ( 275)  397 92.0 3.6e-19
CCDS11998.1 SOCS6 gene_id:9306|Hs108|chr18         ( 535)  339 80.0 2.8e-15
CCDS32637.1 SOCS7 gene_id:30837|Hs108|chr17        ( 581)  303 72.5 5.4e-13


>>CCDS9047.1 SOCS2 gene_id:8835|Hs108|chr12               (198 aa)
 initn: 1338 init1: 1338 opt: 1338  Z-score: 1523.5  bits: 288.7 E(32554): 1.5e-78
Smith-Waterman score: 1338; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198)

               10        20        30        40        50        60
pF1KE0 MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 KLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 SVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWG
              130       140       150       160       170       180

              190        
pF1KE0 LPLPTRLKDYLEEYKFQV
       ::::::::::::::::::
CCDS90 LPLPTRLKDYLEEYKFQV
              190        

>>CCDS2831.1 CISH gene_id:1154|Hs108|chr3                 (258 aa)
 initn: 540 init1: 383 opt: 397  Z-score: 457.9  bits: 92.0 E(32554): 3.5e-19
Smith-Waterman score: 519; 41.7% identity (65.4% similar) in 211 aa overlap (14-198:48-258)

                                10        20        30        40   
pF1KE0                  MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALREL
                                     ::: .:  .  .. .:  .   .::..  :
CCDS28 GQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYL
        20        30        40        50        60        70       

            50        60        70        80        90       100   
pF1KE0 GQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGK
        ..::::::.:..::...:.. ::::::.:::.: .::.:.::::. ::::.:::: :..
CCDS28 RESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSS
        80        90       100       110       120       130       

           110       120       130                                 
pF1KE0 FRLDSIICVKSKLKQFDSVVHLIDYYVQMCK-DKRTG-----------------------
       :::::    . ..  : .:: :...::  :  : :.                        
CCDS28 FRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALPMPKEDAPSDPAL
       140       150       160       170       180       190       

     140       150         160       170       180       190       
pF1KE0 PEAPRNGTVHLYLTKPLY--TSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQ
       :  :   .::: :..:.   .:: ::::::::.::. .. .  :::: :. :::..: ::
CCDS28 PAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQ
       200       210       220       230       240       250       

        
pF1KE0 V
       .
CCDS28 L
        

>>CCDS46834.1 CISH gene_id:1154|Hs108|chr3                (275 aa)
 initn: 540 init1: 383 opt: 397  Z-score: 457.5  bits: 92.0 E(32554): 3.6e-19
Smith-Waterman score: 519; 41.7% identity (65.4% similar) in 211 aa overlap (14-198:65-275)

                                10        20        30        40   
pF1KE0                  MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALREL
                                     ::: .:  .  .. .:  .   .::..  :
CCDS46 GQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYL
           40        50        60        70        80        90    

            50        60        70        80        90       100   
pF1KE0 GQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGK
        ..::::::.:..::...:.. ::::::.:::.: .::.:.::::. ::::.:::: :..
CCDS46 RESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSS
          100       110       120       130       140       150    

           110       120       130                                 
pF1KE0 FRLDSIICVKSKLKQFDSVVHLIDYYVQMCK-DKRTG-----------------------
       :::::    . ..  : .:: :...::  :  : :.                        
CCDS46 FRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALPMPKEDAPSDPAL
          160       170       180       190       200       210    

     140       150         160       170       180       190       
pF1KE0 PEAPRNGTVHLYLTKPLY--TSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQ
       :  :   .::: :..:.   .:: ::::::::.::. .. .  :::: :. :::..: ::
CCDS46 PAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQ
          220       230       240       250       260       270    

        
pF1KE0 V
       .
CCDS46 L
        

>>CCDS11998.1 SOCS6 gene_id:9306|Hs108|chr18              (535 aa)
 initn: 298 init1: 200 opt: 339  Z-score: 387.9  bits: 80.0 E(32554): 2.8e-15
Smith-Waterman score: 339; 31.9% identity (65.7% similar) in 207 aa overlap (2-196:339-535)

                                             10        20        30
pF1KE0                              MTLRC-LEPSGNGGEGTRSQWGTAGSAEEPS
                                     ..:: :. . :.. :.   . .. :.   .
CCDS11 PLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDSVQSS---G
      310       320       330       340       350       360        

                40        50        60        70        80         
pF1KE0 PQAAR-LAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTS
       :...  :.. :..:.. ::::: .:  ::. :: ..:.:.::.:::: . :::..: .. 
CCDS11 PMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSH
         370       380       390       400       410       420     

      90       100       110       120       130       140         
pF1KE0 AGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGP------EAP
       .   . :::...:.: .      .  ..   :.: ::.. .   .:...:       . :
CCDS11 GKTLHTRIEHSNGRFSFYE----QPDVEGHTSIVDLIEHSI---RDSENGAFCYSRSRLP
         430       440           450       460          470        

           150         160       170         180       190        
pF1KE0 RNGTVHLYLTKPL--YTSAPSLQHLCRLTINKCT--GAIWGLPLPTRLKDYLEEYKFQV
        ..:  . ::.:.  . .. :::.:::..: . :    :  ::::...::::.: ..  
CCDS11 GSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY  
      480       490       500       510       520       530       

>>CCDS32637.1 SOCS7 gene_id:30837|Hs108|chr17             (581 aa)
 initn: 283 init1: 202 opt: 303  Z-score: 346.7  bits: 72.5 E(32554): 5.4e-13
Smith-Waterman score: 303; 32.2% identity (61.5% similar) in 174 aa overlap (31-196:383-553)

               10        20        30        40        50        60
pF1KE0 MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKE
                                     :... .: .:::: . ::::: :. ..:. 
CCDS32 PDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEM
            360       370       380       390       400       410  

               70        80        90       100       110       120
pF1KE0 KLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFD
       :::  :.:.::.::::   :.:..: ....   . :.:.  : :   :. :  .   . .
CCDS32 KLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTF---SLWCHPKFEDRCQ
            420       430       440       450          460         

              130           140       150         160       170    
pF1KE0 SVVHLIDYYVQMCKDKR----TGPEAPRNGTVHLYLTKPL--YTSAPSLQHLCRLTINKC
       :::..:   ..  :. .       ..:    . . :  :.  .... :::::::. : . 
CCDS32 SVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQL
     470       480       490       500       510       520         

            180       190                                  
pF1KE0 T--GAIWGLPLPTRLKDYLEEYKFQV                          
       .    :  ::::  : .:.... .                            
CCDS32 VRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST
     530       540       550       560       570       580 




198 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 20:18:11 2016 done: Sat Nov  5 20:18:11 2016
 Total Scan time:  2.110 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]