FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0630, 371 aa 1>>>pF1KE0630 371 - 371 aa - 371 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7519+/-0.000288; mu= 6.9879+/- 0.018 mean_var=165.3640+/-34.100, 0's: 0 Z-trim(123.2): 16 B-trim: 2518 in 1/57 Lambda= 0.099736 statistics sampled from 42478 (42505) to 42478 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.498), width: 16 Scan time: 9.160 The best scores are: opt bits E(85289) NP_751907 (OMIM: 611256) NADPH oxidase organizer 1 ( 371) 2548 377.9 2e-104 NP_653204 (OMIM: 611256) NADPH oxidase organizer 1 ( 370) 2530 375.3 1.2e-103 NP_751908 (OMIM: 611256) NADPH oxidase organizer 1 ( 376) 2528 375.1 1.5e-103 XP_005255156 (OMIM: 611256) PREDICTED: NADPH oxida ( 376) 2528 375.1 1.5e-103 XP_016878416 (OMIM: 611256) PREDICTED: NADPH oxida ( 376) 2528 375.1 1.5e-103 XP_016878417 (OMIM: 611256) PREDICTED: NADPH oxida ( 376) 2528 375.1 1.5e-103 NP_001254650 (OMIM: 611256) NADPH oxidase organize ( 375) 2510 372.5 8.9e-103 >>NP_751907 (OMIM: 611256) NADPH oxidase organizer 1 iso (371 aa) initn: 2548 init1: 2548 opt: 2548 Z-score: 1995.8 bits: 377.9 E(85289): 2e-104 Smith-Waterman score: 2548; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371) 10 20 30 40 50 60 pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC 310 320 330 340 350 360 370 pF1KE0 VDSVPHPTTEQ ::::::::::: NP_751 VDSVPHPTTEQ 370 >>NP_653204 (OMIM: 611256) NADPH oxidase organizer 1 iso (370 aa) initn: 2215 init1: 2215 opt: 2530 Z-score: 1981.8 bits: 375.3 E(85289): 1.2e-103 Smith-Waterman score: 2530; 99.7% identity (99.7% similar) in 371 aa overlap (1-371:1-370) 10 20 30 40 50 60 pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_653 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLK-TLKETFPVEA 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC 300 310 320 330 340 350 370 pF1KE0 VDSVPHPTTEQ ::::::::::: NP_653 VDSVPHPTTEQ 360 370 >>NP_751908 (OMIM: 611256) NADPH oxidase organizer 1 iso (376 aa) initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103 Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376) 10 20 30 40 50 60 pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI :::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_751 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 310 320 330 340 350 360 360 370 pF1KE0 RPRGCVDSVPHPTTEQ :::::::::::::::: NP_751 RPRGCVDSVPHPTTEQ 370 >>XP_005255156 (OMIM: 611256) PREDICTED: NADPH oxidase o (376 aa) initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103 Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376) 10 20 30 40 50 60 pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI :::::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_005 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 310 320 330 340 350 360 360 370 pF1KE0 RPRGCVDSVPHPTTEQ :::::::::::::::: XP_005 RPRGCVDSVPHPTTEQ 370 >>XP_016878416 (OMIM: 611256) PREDICTED: NADPH oxidase o (376 aa) initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103 Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376) 10 20 30 40 50 60 pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI :::::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_016 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 310 320 330 340 350 360 360 370 pF1KE0 RPRGCVDSVPHPTTEQ :::::::::::::::: XP_016 RPRGCVDSVPHPTTEQ 370 >>XP_016878417 (OMIM: 611256) PREDICTED: NADPH oxidase o (376 aa) initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103 Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376) 10 20 30 40 50 60 pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI :::::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_016 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 310 320 330 340 350 360 360 370 pF1KE0 RPRGCVDSVPHPTTEQ :::::::::::::::: XP_016 RPRGCVDSVPHPTTEQ 370 >>NP_001254650 (OMIM: 611256) NADPH oxidase organizer 1 (375 aa) initn: 2384 init1: 2065 opt: 2510 Z-score: 1966.1 bits: 372.5 E(85289): 8.9e-103 Smith-Waterman score: 2510; 98.4% identity (98.4% similar) in 376 aa overlap (1-371:1-375) 10 20 30 40 50 60 pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_001 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLK-TLKETFPVEA 10 20 30 40 50 70 80 90 100 110 pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI :::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_001 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 300 310 320 330 340 350 360 370 pF1KE0 RPRGCVDSVPHPTTEQ :::::::::::::::: NP_001 RPRGCVDSVPHPTTEQ 360 370 371 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:35:32 2016 done: Wed Nov 2 19:35:33 2016 Total Scan time: 9.160 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]