FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0631, 200 aa 1>>>pF1KE0631 200 - 200 aa - 200 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5772+/-0.000425; mu= 18.4117+/- 0.027 mean_var=156.4621+/-37.987, 0's: 0 Z-trim(113.0): 410 B-trim: 1253 in 1/52 Lambda= 0.102534 statistics sampled from 21541 (22125) to 21541 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.259), width: 16 Scan time: 4.640 The best scores are: opt bits E(85289) NP_002559 (OMIM: 604679) polyadenylate-binding pro ( 636) 1076 171.8 2.1e-42 XP_005250918 (OMIM: 604679) PREDICTED: polyadenyla ( 636) 1076 171.8 2.1e-42 NP_001129126 (OMIM: 603407) polyadenylate-binding ( 631) 1044 167.1 5.5e-41 NP_003810 (OMIM: 603407) polyadenylate-binding pro ( 644) 1044 167.1 5.5e-41 NP_001129125 (OMIM: 603407) polyadenylate-binding ( 660) 1044 167.1 5.6e-41 NP_112241 (OMIM: 604680) polyadenylate-binding pro ( 631) 965 155.4 1.8e-37 NP_543022 (OMIM: 300407) polyadenylate-binding pro ( 382) 782 127.9 2e-29 NP_005841 (OMIM: 154400,605593) splicing factor 3B ( 424) 359 65.4 1.4e-10 XP_016869913 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 293 55.5 1.1e-07 NP_001164666 (OMIM: 601673) ELAV-like protein 2 is ( 346) 293 55.5 1.1e-07 NP_001164668 (OMIM: 601673) ELAV-like protein 2 is ( 346) 293 55.5 1.1e-07 XP_016869914 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 293 55.5 1.1e-07 XP_016869910 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 293 55.5 1.2e-07 XP_016869911 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 293 55.5 1.2e-07 NP_004423 (OMIM: 601673) ELAV-like protein 2 isofo ( 359) 293 55.5 1.2e-07 XP_016869908 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 293 55.5 1.2e-07 XP_016869909 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 293 55.5 1.2e-07 XP_016869912 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 293 55.5 1.2e-07 XP_006716799 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_011516088 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_005251452 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_005251450 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_005251451 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_011516086 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_011516087 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_016869907 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 293 55.5 1.2e-07 XP_016869906 (OMIM: 601673) PREDICTED: ELAV-like p ( 373) 293 55.6 1.2e-07 XP_011516085 (OMIM: 601673) PREDICTED: ELAV-like p ( 374) 293 55.6 1.2e-07 XP_016869905 (OMIM: 601673) PREDICTED: ELAV-like p ( 375) 293 55.6 1.2e-07 XP_011516079 (OMIM: 601673) PREDICTED: ELAV-like p ( 375) 293 55.6 1.2e-07 XP_016869904 (OMIM: 601673) PREDICTED: ELAV-like p ( 376) 293 55.6 1.2e-07 XP_011516078 (OMIM: 601673) PREDICTED: ELAV-like p ( 376) 293 55.6 1.2e-07 XP_016869902 (OMIM: 601673) PREDICTED: ELAV-like p ( 387) 293 55.6 1.2e-07 XP_016869903 (OMIM: 601673) PREDICTED: ELAV-like p ( 387) 293 55.6 1.2e-07 XP_016869898 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 293 55.6 1.2e-07 XP_011516076 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 293 55.6 1.2e-07 XP_016869901 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 293 55.6 1.2e-07 XP_016869897 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 293 55.6 1.2e-07 XP_016869899 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 293 55.6 1.2e-07 XP_016869900 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 293 55.6 1.2e-07 XP_011516081 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 293 55.6 1.2e-07 XP_006716798 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 293 55.6 1.2e-07 XP_006716797 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 293 55.6 1.2e-07 XP_011516082 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 293 55.6 1.2e-07 XP_011516080 (OMIM: 601673) PREDICTED: ELAV-like p ( 392) 293 55.6 1.2e-07 NP_001311138 (OMIM: 168360) ELAV-like protein 4 is ( 352) 290 55.1 1.6e-07 NP_001311144 (OMIM: 168360) ELAV-like protein 4 is ( 358) 290 55.1 1.6e-07 XP_016856028 (OMIM: 168360) PREDICTED: ELAV-like p ( 359) 290 55.1 1.6e-07 NP_001311143 (OMIM: 168360) ELAV-like protein 4 is ( 365) 290 55.1 1.6e-07 NP_001311141 (OMIM: 168360) ELAV-like protein 4 is ( 365) 290 55.1 1.6e-07 >>NP_002559 (OMIM: 604679) polyadenylate-binding protein (636 aa) initn: 1201 init1: 1076 opt: 1076 Z-score: 882.4 bits: 171.8 E(85289): 2.1e-42 Smith-Waterman score: 1076; 80.1% identity (93.4% similar) in 196 aa overlap (1-196:10-205) 10 20 30 40 50 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQ :::::::::::.::::::::::::::::::::.::: ::::::::::::.: NP_002 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFS ::.::.:::.:.:::::::.::::::::::::::::::::.::::: :.:::::::. :: NP_002 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE ::::::::::.:::.: ::::::::. ::.:::::. ::::.:: ::.:::::::.:::: NP_002 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 130 140 150 160 170 180 180 190 200 pF1KE0 AERGAWARQSTSADVKDFEEDTDEEATLR :: :: :.. :.. .:.: :: :.: NP_002 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 190 200 210 220 230 240 >-- initn: 409 init1: 172 opt: 268 Z-score: 236.4 bits: 52.3 E(85289): 2e-06 Smith-Waterman score: 268; 29.7% identity (59.3% similar) in 172 aa overlap (18-172:207-376) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAY : . :. :: ::... :. . .: :... NP_002 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 180 190 200 210 220 230 50 60 70 80 90 pF1KE0 VNYQQPVDAKRALETLNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVG :.... ::..:.. .: ..:. . . .:. : : .:: NP_002 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGV- 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE0 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMN :...::: ::.. : . :: ::.: : :: . ::.::: :.. : : .:. :: NP_002 NLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMN 300 310 320 330 340 350 160 170 180 190 200 pF1KE0 GMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR : .. . ..:. . ..::.: NP_002 GRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIP 360 370 380 390 400 410 >>XP_005250918 (OMIM: 604679) PREDICTED: polyadenylate-b (636 aa) initn: 1201 init1: 1076 opt: 1076 Z-score: 882.4 bits: 171.8 E(85289): 2.1e-42 Smith-Waterman score: 1076; 80.1% identity (93.4% similar) in 196 aa overlap (1-196:10-205) 10 20 30 40 50 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQ :::::::::::.::::::::::::::::::::.::: ::::::::::::.: XP_005 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFS ::.::.:::.:.:::::::.::::::::::::::::::::.::::: :.:::::::. :: XP_005 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE ::::::::::.:::.: ::::::::. ::.:::::. ::::.:: ::.:::::::.:::: XP_005 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 130 140 150 160 170 180 180 190 200 pF1KE0 AERGAWARQSTSADVKDFEEDTDEEATLR :: :: :.. :.. .:.: :: :.: XP_005 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 190 200 210 220 230 240 >-- initn: 409 init1: 172 opt: 268 Z-score: 236.4 bits: 52.3 E(85289): 2e-06 Smith-Waterman score: 268; 29.7% identity (59.3% similar) in 172 aa overlap (18-172:207-376) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAY : . :. :: ::... :. . .: :... XP_005 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 180 190 200 210 220 230 50 60 70 80 90 pF1KE0 VNYQQPVDAKRALETLNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVG :.... ::..:.. .: ..:. . . .:. : : .:: XP_005 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGV- 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE0 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMN :...::: ::.. : . :: ::.: : :: . ::.::: :.. : : .:. :: XP_005 NLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMN 300 310 320 330 340 350 160 170 180 190 200 pF1KE0 GMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR : .. . ..:. . ..::.: XP_005 GRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIP 360 370 380 390 400 410 >>NP_001129126 (OMIM: 603407) polyadenylate-binding prot (631 aa) initn: 1149 init1: 1044 opt: 1044 Z-score: 856.8 bits: 167.1 E(85289): 5.5e-41 Smith-Waterman score: 1044; 76.6% identity (93.4% similar) in 197 aa overlap (1-197:10-206) 10 20 30 40 50 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQ :::::::::: .:::::::::::::::.::::.::: ::::::::::::.: NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFS ::.::.:::.:.:::::::.:.:::::::::::::::::::::::: :.:::::::. :: NP_001 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE ::::::::::.:::.: :::.::::. ::.:..::. ::::.:: ::.:::::::.:::: NP_001 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 130 140 150 160 170 180 180 190 200 pF1KE0 AERGAWARQSTSADVKDFEEDTDEEATLR :: :: :.. :.. .:.: :..:.:. NP_001 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 190 200 210 220 230 240 >-- initn: 259 init1: 191 opt: 288 Z-score: 252.5 bits: 55.2 E(85289): 2.5e-07 Smith-Waterman score: 288; 33.7% identity (61.6% similar) in 172 aa overlap (18-172:207-376) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAY : : :: : ::... :: . .: :... NP_001 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGF 180 190 200 210 220 230 50 60 70 80 90 pF1KE0 VNYQQPVDAKRALETLNFDVIKGRPVRIMWSQ----RDPSLRKS-------------GVG :.:.. ::..:.: .: :.:. . . .: :. :... :: NP_001 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV- 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE0 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMN :..:::: :::.. : . :: ::.: : :: .. ::.::: :.. : : .:. :: NP_001 NLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMN 300 310 320 330 340 350 160 170 180 190 200 pF1KE0 GMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR : ... . ..:. . ..::.: NP_001 GRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVP 360 370 380 390 400 410 >>NP_003810 (OMIM: 603407) polyadenylate-binding protein (644 aa) initn: 1149 init1: 1044 opt: 1044 Z-score: 856.8 bits: 167.1 E(85289): 5.5e-41 Smith-Waterman score: 1044; 76.6% identity (93.4% similar) in 197 aa overlap (1-197:10-206) 10 20 30 40 50 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQ :::::::::: .:::::::::::::::.::::.::: ::::::::::::.: NP_003 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFS ::.::.:::.:.:::::::.:.:::::::::::::::::::::::: :.:::::::. :: NP_003 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE ::::::::::.:::.: :::.::::. ::.:..::. ::::.:: ::.:::::::.:::: NP_003 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 130 140 150 160 170 180 180 190 200 pF1KE0 AERGAWARQSTSADVKDFEEDTDEEATLR :: :: :.. :.. .:.: :..:.:. NP_003 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 190 200 210 220 230 240 >-- initn: 259 init1: 191 opt: 288 Z-score: 252.4 bits: 55.3 E(85289): 2.6e-07 Smith-Waterman score: 288; 33.7% identity (61.6% similar) in 172 aa overlap (18-172:207-376) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAY : : :: : ::... :: . .: :... NP_003 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGF 180 190 200 210 220 230 50 60 70 80 90 pF1KE0 VNYQQPVDAKRALETLNFDVIKGRPVRIMWSQ----RDPSLRKS-------------GVG :.:.. ::..:.: .: :.:. . . .: :. :... :: NP_003 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV- 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE0 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMN :..:::: :::.. : . :: ::.: : :: .. ::.::: :.. : : .:. :: NP_003 NLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMN 300 310 320 330 340 350 160 170 180 190 200 pF1KE0 GMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR : ... . ..:. . ..::.: NP_003 GRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVP 360 370 380 390 400 410 >>NP_001129125 (OMIM: 603407) polyadenylate-binding prot (660 aa) initn: 1149 init1: 1044 opt: 1044 Z-score: 856.7 bits: 167.1 E(85289): 5.6e-41 Smith-Waterman score: 1044; 76.6% identity (93.4% similar) in 197 aa overlap (1-197:10-206) 10 20 30 40 50 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQ :::::::::: .:::::::::::::::.::::.::: ::::::::::::.: NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFS ::.::.:::.:.:::::::.:.:::::::::::::::::::::::: :.:::::::. :: NP_001 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE ::::::::::.:::.: :::.::::. ::.:..::. ::::.:: ::.:::::::.:::: NP_001 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 130 140 150 160 170 180 180 190 200 pF1KE0 AERGAWARQSTSADVKDFEEDTDEEATLR :: :: :.. :.. .:.: :..:.:. NP_001 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 190 200 210 220 230 240 >-- initn: 259 init1: 191 opt: 288 Z-score: 252.3 bits: 55.3 E(85289): 2.6e-07 Smith-Waterman score: 288; 33.7% identity (61.6% similar) in 172 aa overlap (18-172:207-376) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAY : : :: : ::... :: . .: :... NP_001 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGF 180 190 200 210 220 230 50 60 70 80 90 pF1KE0 VNYQQPVDAKRALETLNFDVIKGRPVRIMWSQ----RDPSLRKS-------------GVG :.:.. ::..:.: .: :.:. . . .: :. :... :: NP_001 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV- 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE0 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMN :..:::: :::.. : . :: ::.: : :: .. ::.::: :.. : : .:. :: NP_001 NLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMN 300 310 320 330 340 350 160 170 180 190 200 pF1KE0 GMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR : ... . ..:. . ..::.: NP_001 GRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVP 360 370 380 390 400 410 >>NP_112241 (OMIM: 604680) polyadenylate-binding protein (631 aa) initn: 1081 init1: 965 opt: 965 Z-score: 793.7 bits: 155.4 E(85289): 1.8e-37 Smith-Waterman score: 965; 73.3% identity (89.2% similar) in 195 aa overlap (2-196:11-205) 10 20 30 40 50 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQ ::::::::::.:::::::::::::::::::::::: :: : .:::::.: NP_112 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFS . ::..::.:.:::::::.::::::::::::::::::::.:.::: :.:.:::::. : NP_112 HTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE ::::::::.:.:::.: ::::::::. .:.::::: ::::.:: ::.:::.:::.:::: NP_112 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 130 140 150 160 170 180 180 190 200 pF1KE0 AERGAWARQSTSADVKDFEEDTDEEATLR :: :: :.. .. .:.: :: :.: NP_112 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 190 200 210 220 230 240 >-- initn: 410 init1: 175 opt: 270 Z-score: 238.1 bits: 52.6 E(85289): 1.6e-06 Smith-Waterman score: 270; 29.2% identity (60.2% similar) in 171 aa overlap (18-172:207-376) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAY : . :. :: ::... :. . .: :... NP_112 KEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 180 190 200 210 220 230 50 60 70 80 90 pF1KE0 VNYQQPVDAKRALETLNFDVIKGRPVRIMWSQ----RDPSLRKS------------GVGN :.... ::..:.. .: ..:. . . .: :. :... : : NP_112 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVN 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE0 VFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNG ...::: ::.. : . :: ::.: : :: . ::.::: :.. : : .:. ::: NP_112 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNG 300 310 320 330 340 350 160 170 180 190 200 pF1KE0 MFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR .. . ..:. . ..::.: NP_112 RIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAA 360 370 380 390 400 410 >>NP_543022 (OMIM: 300407) polyadenylate-binding protein (382 aa) initn: 761 init1: 761 opt: 782 Z-score: 649.2 bits: 127.9 E(85289): 2e-29 Smith-Waterman score: 782; 59.7% identity (81.6% similar) in 196 aa overlap (2-196:18-213) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLG :.:::::: :.::: :::.:: ::::. ::::: .:: :: NP_543 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 YAYVNYQQPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNK :.:::.. :.::. ::.:.:::.:.:.: :.:::: : ::::::::.::::: :.:::. NP_543 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 ALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRF ::. .::::::::::::.::..: :::..:::.. .:.::: :::. :: :...:::: NP_543 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF 130 140 150 160 170 180 170 180 190 200 pF1KE0 KSHKEREAERGAWARQS-TSADVKDFEEDTDEEATLR : .:: :: . : . :.. ::.. .: :.: NP_543 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG 190 200 210 220 230 240 NP_543 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP 250 260 270 280 290 300 >>NP_005841 (OMIM: 154400,605593) splicing factor 3B sub (424 aa) initn: 318 init1: 148 opt: 359 Z-score: 310.7 bits: 65.4 E(85289): 1.4e-10 Smith-Waterman score: 359; 35.6% identity (68.1% similar) in 188 aa overlap (2-184:13-197) 10 20 30 40 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVN :..::: : .:.: .:.: : :::... .. .:..: . ::..:. NP_005 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 YQQPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVG-NVFIKNLGKTIDNKALYN . . :: :.. .:. . :.:.:. .. . .. :: :.:: :: ::.: ::. NP_005 FLSEEDADYAIKIMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYD 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 IFSAFGNILSC-KVACD-EKG-PKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK ::::: ::. :. : . : :::.:..: . .... ::..:::..: : : :. . NP_005 TFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YA 120 130 140 150 160 170 170 180 190 200 pF1KE0 SHKEREAER-GAWARQSTSADVKDFEEDTDEEATLR .:. ..:: :. :.. .: NP_005 FKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGM 180 190 200 210 220 230 >>XP_016869913 (OMIM: 601673) PREDICTED: ELAV-like prote (346 aa) initn: 280 init1: 152 opt: 293 Z-score: 258.6 bits: 55.5 E(85289): 1.1e-07 Smith-Waterman score: 293; 35.1% identity (67.5% similar) in 151 aa overlap (3-151:40-188) 10 20 30 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIR .: :. : ..:. : :. : : : . XP_016 TCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 ICRDKITRRSLGYAYVNYQQPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNV . ::::: .::::..::: .: ::..:..::: .. . ... ... :: . .:. XP_016 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR--PSSASIRDANL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 FIKNLGKTIDNKALYNIFSAFGNILSCKVACDE-KG-PKGYGFVHFQKQESAERAIDVMN ....: ::. .: : ..:: .: :.. .. :. : .: ::..:.:. ::.:: .: XP_016 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLN 130 140 150 160 170 180 160 170 180 190 200 pF1KE0 GMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR : XP_016 GQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRFSPMTIDGM 190 200 210 220 230 240 >>NP_001164666 (OMIM: 601673) ELAV-like protein 2 isofor (346 aa) initn: 280 init1: 152 opt: 293 Z-score: 258.6 bits: 55.5 E(85289): 1.1e-07 Smith-Waterman score: 293; 35.1% identity (67.5% similar) in 151 aa overlap (3-151:40-188) 10 20 30 pF1KE0 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIR .: :. : ..:. : :. : : : . NP_001 TCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 ICRDKITRRSLGYAYVNYQQPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNV . ::::: .::::..::: .: ::..:..::: .. . ... ... :: . .:. NP_001 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR--PSSASIRDANL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 FIKNLGKTIDNKALYNIFSAFGNILSCKVACDE-KG-PKGYGFVHFQKQESAERAIDVMN ....: ::. .: : ..:: .: :.. .. :. : .: ::..:.:. ::.:: .: NP_001 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLN 130 140 150 160 170 180 160 170 180 190 200 pF1KE0 GMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR : NP_001 GQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRFSPMTIDGM 190 200 210 220 230 240 200 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:33:35 2016 done: Wed Nov 2 19:33:36 2016 Total Scan time: 4.640 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]