FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0633, 202 aa 1>>>pF1KE0633 202 - 202 aa - 202 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6807+/-0.000701; mu= 13.7589+/- 0.042 mean_var=103.1030+/-20.423, 0's: 0 Z-trim(113.1): 12 B-trim: 0 in 0/52 Lambda= 0.126310 statistics sampled from 13787 (13799) to 13787 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.424), width: 16 Scan time: 2.200 The best scores are: opt bits E(32554) CCDS12473.1 U2AF1L4 gene_id:199746|Hs108|chr19 ( 202) 1408 266.0 1.2e-71 CCDS42551.1 U2AF1L4 gene_id:199746|Hs108|chr19 ( 181) 723 141.1 4e-34 CCDS82648.1 U2AF1L5 gene_id:102724594|Hs108|chr21 ( 167) 369 76.5 9.9e-15 CCDS42948.1 U2AF1 gene_id:7307|Hs108|chr21 ( 167) 369 76.5 9.9e-15 CCDS82650.1 U2AF1L5 gene_id:102724594|Hs108|chr21 ( 240) 369 76.7 1.3e-14 CCDS82649.1 U2AF1L5 gene_id:102724594|Hs108|chr21 ( 240) 369 76.7 1.3e-14 CCDS13694.1 U2AF1 gene_id:7307|Hs108|chr21 ( 240) 369 76.7 1.3e-14 CCDS33574.1 U2AF1 gene_id:7307|Hs108|chr21 ( 240) 369 76.7 1.3e-14 >>CCDS12473.1 U2AF1L4 gene_id:199746|Hs108|chr19 (202 aa) initn: 1408 init1: 1408 opt: 1408 Z-score: 1400.1 bits: 266.0 E(32554): 1.2e-71 Smith-Waterman score: 1408; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202) 10 20 30 40 50 60 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 NVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RTSRGSSMGGDPGAGHPRGSILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RTSRGSSMGGDPGAGHPRGSILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQ 130 140 150 160 170 180 190 200 pF1KE0 DLSSKPPSLSCPILPRLPGSIM :::::::::::::::::::::: CCDS12 DLSSKPPSLSCPILPRLPGSIM 190 200 >>CCDS42551.1 U2AF1L4 gene_id:199746|Hs108|chr19 (181 aa) initn: 717 init1: 717 opt: 723 Z-score: 726.1 bits: 141.1 E(32554): 4e-34 Smith-Waterman score: 723; 84.3% identity (89.8% similar) in 127 aa overlap (1-125:1-127) 10 20 30 40 50 60 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP :::::::::::::::::::::::::::::::::::::::::::.. :.. : . CCDS42 NVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGELSPVTDFRESCCRQYE 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 --RTSRGSSMGGDPGAGHPRGSILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCS . .:: CCDS42 MGECTRGGFCNFMHLRPISQNLQRQLYGRGPRRRSPPRFHTGHHPRERNHRCSPDHWHGR 130 140 150 160 170 180 >>CCDS82648.1 U2AF1L5 gene_id:102724594|Hs108|chr21 (167 aa) initn: 432 init1: 356 opt: 369 Z-score: 377.9 bits: 76.5 E(32554): 9.9e-15 Smith-Waterman score: 369; 61.6% identity (81.4% similar) in 86 aa overlap (42-125:8-93) 20 30 40 50 60 70 pF1KE0 EKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEMNVCDNLGDHLV : .:::::..:::::.:::::::::::::: CCDS82 MQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLV 10 20 30 80 90 100 110 120 pF1KE0 GNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP--RTSRGSSMG ::::::::::::.:.:: .:.::::::: .:... :.. : . . .:: CCDS82 GNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GDPGAGHPRGSILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSL CCDS82 FMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRR 100 110 120 130 140 150 >>CCDS42948.1 U2AF1 gene_id:7307|Hs108|chr21 (167 aa) initn: 432 init1: 356 opt: 369 Z-score: 377.9 bits: 76.5 E(32554): 9.9e-15 Smith-Waterman score: 369; 61.6% identity (81.4% similar) in 86 aa overlap (42-125:8-93) 20 30 40 50 60 70 pF1KE0 EKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEMNVCDNLGDHLV : .:::::..:::::.:::::::::::::: CCDS42 MQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLV 10 20 30 80 90 100 110 120 pF1KE0 GNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP--RTSRGSSMG ::::::::::::.:.:: .:.::::::: .:... :.. : . . .:: CCDS42 GNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GDPGAGHPRGSILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSL CCDS42 FMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRR 100 110 120 130 140 150 >>CCDS82650.1 U2AF1L5 gene_id:102724594|Hs108|chr21 (240 aa) initn: 730 init1: 356 opt: 369 Z-score: 375.9 bits: 76.7 E(32554): 1.3e-14 Smith-Waterman score: 540; 55.3% identity (66.0% similar) in 159 aa overlap (8-125:8-166) 10 20 30 40 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQ---------------- ::::::::::::::::::.:::::::::::::::::: CCDS82 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQ 10 20 30 40 50 60 50 60 70 80 pF1KE0 -----------------------EVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRRE :::::..:::::.:::::::::::::::::::::::: CCDS82 TADGSHCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 90 100 110 120 130 pF1KE0 EDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP--RTSRGSSMGGDPGAGHPRG ::.:.:: .:.::::::: .:... :.. : . . .:: CCDS82 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 140 150 160 170 180 190 pF1KE0 SILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSLSCPILPRLPG CCDS82 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 >>CCDS82649.1 U2AF1L5 gene_id:102724594|Hs108|chr21 (240 aa) initn: 728 init1: 356 opt: 369 Z-score: 375.9 bits: 76.7 E(32554): 1.3e-14 Smith-Waterman score: 540; 55.3% identity (66.0% similar) in 159 aa overlap (8-125:8-166) 10 20 30 40 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQ---------------- ::::::::::::::::::.:::::::::::::::::: CCDS82 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ 10 20 30 40 50 60 50 60 70 80 pF1KE0 -----------------------EVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRRE :::::..:::::.:::::::::::::::::::::::: CCDS82 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 90 100 110 120 130 pF1KE0 EDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP--RTSRGSSMGGDPGAGHPRG ::.:.:: .:.::::::: .:... :.. : . . .:: CCDS82 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 140 150 160 170 180 190 pF1KE0 SILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSLSCPILPRLPG CCDS82 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 >>CCDS13694.1 U2AF1 gene_id:7307|Hs108|chr21 (240 aa) initn: 728 init1: 356 opt: 369 Z-score: 375.9 bits: 76.7 E(32554): 1.3e-14 Smith-Waterman score: 540; 55.3% identity (66.0% similar) in 159 aa overlap (8-125:8-166) 10 20 30 40 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQ---------------- ::::::::::::::::::.:::::::::::::::::: CCDS13 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ 10 20 30 40 50 60 50 60 70 80 pF1KE0 -----------------------EVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRRE :::::..:::::.:::::::::::::::::::::::: CCDS13 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 90 100 110 120 130 pF1KE0 EDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP--RTSRGSSMGGDPGAGHPRG ::.:.:: .:.::::::: .:... :.. : . . .:: CCDS13 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 140 150 160 170 180 190 pF1KE0 SILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSLSCPILPRLPG CCDS13 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 >>CCDS33574.1 U2AF1 gene_id:7307|Hs108|chr21 (240 aa) initn: 730 init1: 356 opt: 369 Z-score: 375.9 bits: 76.7 E(32554): 1.3e-14 Smith-Waterman score: 540; 55.3% identity (66.0% similar) in 159 aa overlap (8-125:8-166) 10 20 30 40 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQ---------------- ::::::::::::::::::.:::::::::::::::::: CCDS33 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQ 10 20 30 40 50 60 50 60 70 80 pF1KE0 -----------------------EVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRRE :::::..:::::.:::::::::::::::::::::::: CCDS33 TADGSHCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 90 100 110 120 130 pF1KE0 EDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFP--RTSRGSSMGGDPGAGHPRG ::.:.:: .:.::::::: .:... :.. : . . .:: CCDS33 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 140 150 160 170 180 190 pF1KE0 SILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSLSCPILPRLPG CCDS33 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 202 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:28:23 2016 done: Wed Nov 2 19:28:24 2016 Total Scan time: 2.200 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]