FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0637, 209 aa 1>>>pF1KE0637 209 - 209 aa - 209 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4739+/-0.000326; mu= 14.4596+/- 0.020 mean_var=104.5340+/-23.057, 0's: 0 Z-trim(117.5): 154 B-trim: 1857 in 1/56 Lambda= 0.125443 statistics sampled from 29320 (29505) to 29320 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.346), width: 16 Scan time: 5.460 The best scores are: opt bits E(85289) NP_006858 (OMIM: 601558) RNA-binding protein with ( 196) 903 173.3 2.4e-43 XP_016868475 (OMIM: 601558) PREDICTED: RNA-binding ( 196) 903 173.3 2.4e-43 NP_001008710 (OMIM: 601558) RNA-binding protein wi ( 196) 903 173.3 2.4e-43 XP_016868471 (OMIM: 601558) PREDICTED: RNA-binding ( 245) 798 154.4 1.5e-37 XP_016868470 (OMIM: 601558) PREDICTED: RNA-binding ( 246) 798 154.4 1.5e-37 XP_016868469 (OMIM: 601558) PREDICTED: RNA-binding ( 264) 798 154.4 1.6e-37 NP_001008711 (OMIM: 601558) RNA-binding protein wi ( 204) 796 153.9 1.7e-37 XP_016868473 (OMIM: 601558) PREDICTED: RNA-binding ( 224) 796 154.0 1.8e-37 XP_016868478 (OMIM: 601558) PREDICTED: RNA-binding ( 176) 791 152.9 2.9e-37 XP_016868477 (OMIM: 601558) PREDICTED: RNA-binding ( 179) 791 153.0 2.9e-37 NP_001008712 (OMIM: 601558) RNA-binding protein wi ( 219) 791 153.0 3.3e-37 XP_016868472 (OMIM: 601558) PREDICTED: RNA-binding ( 245) 777 150.6 2.1e-36 XP_016868479 (OMIM: 601558) PREDICTED: RNA-binding ( 162) 621 122.1 4.9e-28 XP_016868476 (OMIM: 601558) PREDICTED: RNA-binding ( 186) 621 122.2 5.4e-28 XP_016868481 (OMIM: 601558) PREDICTED: RNA-binding ( 136) 610 120.1 1.7e-27 XP_016868474 (OMIM: 601558) PREDICTED: RNA-binding ( 202) 429 87.5 1.7e-17 XP_016868480 (OMIM: 601558) PREDICTED: RNA-binding ( 160) 291 62.4 4.6e-10 >>NP_006858 (OMIM: 601558) RNA-binding protein with mult (196 aa) initn: 827 init1: 782 opt: 903 Z-score: 899.1 bits: 173.3 E(85289): 2.4e-43 Smith-Waterman score: 903; 69.0% identity (83.0% similar) in 200 aa overlap (10-209:3-196) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: NP_006 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: NP_006 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: NP_006 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.::::.:: : :..:.:::: :::: NP_006 ---ASLHAQMRWLPPSEATSQGWKSRQFC 180 190 >>XP_016868475 (OMIM: 601558) PREDICTED: RNA-binding pro (196 aa) initn: 827 init1: 782 opt: 903 Z-score: 899.1 bits: 173.3 E(85289): 2.4e-43 Smith-Waterman score: 903; 69.0% identity (83.0% similar) in 200 aa overlap (10-209:3-196) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: XP_016 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: XP_016 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: XP_016 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.::::.:: : :..:.:::: :::: XP_016 ---ASLHAQMRWLPPSEATSQGWKSRQFC 180 190 >>NP_001008710 (OMIM: 601558) RNA-binding protein with m (196 aa) initn: 827 init1: 782 opt: 903 Z-score: 899.1 bits: 173.3 E(85289): 2.4e-43 Smith-Waterman score: 903; 69.0% identity (83.0% similar) in 200 aa overlap (10-209:3-196) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: NP_001 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: NP_001 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: NP_001 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.::::.:: : :..:.:::: :::: NP_001 ---ASLHAQMRWLPPSEATSQGWKSRQFC 180 190 >>XP_016868471 (OMIM: 601558) PREDICTED: RNA-binding pro (245 aa) initn: 847 init1: 782 opt: 798 Z-score: 795.2 bits: 154.4 E(85289): 1.5e-37 Smith-Waterman score: 798; 68.6% identity (81.6% similar) in 185 aa overlap (10-194:3-181) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: XP_016 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: XP_016 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: XP_016 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.::::: : XP_016 ---ASLHAQVSSPPPAMGALCPRPVLSHLSQEGSSNSALCLVSKWIQMHQAMSRGCAGSL 180 190 200 210 220 >>XP_016868470 (OMIM: 601558) PREDICTED: RNA-binding pro (246 aa) initn: 847 init1: 782 opt: 798 Z-score: 795.2 bits: 154.4 E(85289): 1.5e-37 Smith-Waterman score: 798; 68.6% identity (81.6% similar) in 185 aa overlap (10-194:3-181) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: XP_016 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: XP_016 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: XP_016 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.::::: : XP_016 ---ASLHAQVSSPPPAMGALCPRPVLSHLSQEGSSNSALCLVSKWIQMHQAMSRGCAGSL 180 190 200 210 220 >>XP_016868469 (OMIM: 601558) PREDICTED: RNA-binding pro (264 aa) initn: 847 init1: 782 opt: 798 Z-score: 794.8 bits: 154.4 E(85289): 1.6e-37 Smith-Waterman score: 798; 68.6% identity (81.6% similar) in 185 aa overlap (10-194:3-181) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: XP_016 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: XP_016 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: XP_016 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.::::: : XP_016 ---ASLHAQVSSPPPAMGALCPRPVLSHLSQEGSSNSALCLVSKWIQMHQAMSRGCAGSL 180 190 200 210 220 >>NP_001008711 (OMIM: 601558) RNA-binding protein with m (204 aa) initn: 784 init1: 784 opt: 796 Z-score: 794.2 bits: 153.9 E(85289): 1.7e-37 Smith-Waterman score: 796; 63.8% identity (78.4% similar) in 199 aa overlap (10-203:3-201) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: NP_001 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: NP_001 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. :::::.. NP_001 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYPASL 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWY-----PSSDTTQQGWKYRQFC : :: :: :... .: NP_001 HAQLCEGQTVRRSHPLSAPSPDSASLAWFPV 180 190 200 >>XP_016868473 (OMIM: 601558) PREDICTED: RNA-binding pro (224 aa) initn: 827 init1: 782 opt: 796 Z-score: 793.7 bits: 154.0 E(85289): 1.8e-37 Smith-Waterman score: 796; 69.6% identity (82.9% similar) in 181 aa overlap (10-190:3-177) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: XP_016 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: XP_016 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: XP_016 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.::::: XP_016 ---ASLHAQVIDTHRPGLHSLHHQSFQTWFPRAHHTTNTYPANRSTLKRLMIPSKSS 180 190 200 210 220 >>XP_016868478 (OMIM: 601558) PREDICTED: RNA-binding pro (176 aa) initn: 827 init1: 782 opt: 791 Z-score: 790.1 bits: 152.9 E(85289): 2.9e-37 Smith-Waterman score: 791; 69.4% identity (82.8% similar) in 180 aa overlap (10-189:3-176) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: XP_016 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: XP_016 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: XP_016 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.:::: XP_016 ---ASLHAQ >>XP_016868477 (OMIM: 601558) PREDICTED: RNA-binding pro (179 aa) initn: 830 init1: 785 opt: 791 Z-score: 790.0 bits: 153.0 E(85289): 2.9e-37 Smith-Waterman score: 791; 69.4% identity (82.8% similar) in 180 aa overlap (10-189:3-176) 10 20 30 40 50 60 pF1KE0 MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGS .::.. . . .. :::::::::::::.:::::::::::::::::::: XP_016 MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMAT :::::..:::::: ::::. :::::::::::::::: :::::::::::::::::.::..: XP_016 LIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 PNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTAT ::::. : .::::.::.: :: :.:::.::::::: .::.::. ::::: XP_016 PNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYP--- 120 130 140 150 160 170 190 200 pF1KE0 AAAAALHAQVRWYPSSDTTQQGWKYRQFC :.:::: XP_016 ---ASLHAQETL 209 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:22:30 2016 done: Wed Nov 2 19:22:31 2016 Total Scan time: 5.460 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]