FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0638, 447 aa 1>>>pF1KE0638 447 - 447 aa - 447 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1511+/-0.000702; mu= 20.5423+/- 0.043 mean_var=125.7394+/-40.454, 0's: 0 Z-trim(112.9): 278 B-trim: 1545 in 2/50 Lambda= 0.114377 statistics sampled from 12968 (13602) to 12968 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.418), width: 16 Scan time: 3.140 The best scores are: opt bits E(32554) CCDS7761.1 CCKBR gene_id:887|Hs108|chr11 ( 447) 2993 505.0 6.2e-143 CCDS81550.1 CCKBR gene_id:887|Hs108|chr11 ( 363) 2138 363.8 1.6e-100 CCDS3438.1 CCKAR gene_id:886|Hs108|chr4 ( 428) 1243 216.2 5.1e-56 CCDS3804.1 NPY5R gene_id:4889|Hs108|chr4 ( 445) 398 76.8 4.9e-14 CCDS4956.1 HCRTR2 gene_id:3062|Hs108|chr6 ( 444) 397 76.6 5.5e-14 CCDS34089.1 NPY1R gene_id:4886|Hs108|chr4 ( 384) 369 71.9 1.2e-12 CCDS3791.1 NPY2R gene_id:4887|Hs108|chr4 ( 381) 368 71.8 1.4e-12 CCDS344.1 HCRTR1 gene_id:3061|Hs108|chr1 ( 425) 368 71.8 1.5e-12 CCDS47004.1 ADRA2C gene_id:152|Hs108|chr4 ( 462) 365 71.4 2.2e-12 CCDS13958.1 GALR3 gene_id:8484|Hs108|chr22 ( 368) 358 70.1 4.3e-12 CCDS3719.1 QRFPR gene_id:84109|Hs108|chr4 ( 431) 357 70.0 5.3e-12 CCDS329.1 OPRD1 gene_id:4985|Hs108|chr1 ( 372) 350 68.8 1.1e-11 CCDS13556.1 OPRL1 gene_id:4987|Hs108|chr20 ( 370) 342 67.4 2.7e-11 CCDS11739.1 GALR2 gene_id:8811|Hs108|chr17 ( 387) 339 67.0 3.9e-11 CCDS53539.1 NPFFR1 gene_id:64106|Hs108|chr10 ( 430) 337 66.7 5.2e-11 CCDS6311.1 TRHR gene_id:7201|Hs108|chr8 ( 398) 335 66.3 6.2e-11 CCDS42856.1 SSTR4 gene_id:6754|Hs108|chr20 ( 388) 334 66.2 6.9e-11 CCDS3552.1 NPFFR2 gene_id:10886|Hs108|chr4 ( 420) 332 65.9 9.1e-11 CCDS47072.1 NPFFR2 gene_id:10886|Hs108|chr4 ( 423) 332 65.9 9.1e-11 CCDS55069.1 OPRM1 gene_id:4988|Hs108|chr6 ( 389) 331 65.7 9.7e-11 CCDS47508.1 OPRM1 gene_id:4988|Hs108|chr6 ( 392) 331 65.7 9.8e-11 CCDS47505.1 OPRM1 gene_id:4988|Hs108|chr6 ( 397) 331 65.7 9.8e-11 CCDS55070.1 OPRM1 gene_id:4988|Hs108|chr6 ( 400) 331 65.7 9.9e-11 CCDS47506.1 OPRM1 gene_id:4988|Hs108|chr6 ( 403) 331 65.7 9.9e-11 CCDS47504.1 OPRM1 gene_id:4988|Hs108|chr6 ( 406) 331 65.7 1e-10 >>CCDS7761.1 CCKBR gene_id:887|Hs108|chr11 (447 aa) initn: 2993 init1: 2993 opt: 2993 Z-score: 2679.6 bits: 505.0 E(32554): 6.2e-143 Smith-Waterman score: 2993; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447) 10 20 30 40 50 60 pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL 370 380 390 400 410 420 430 440 pF1KE0 PDEDPPTPSIASLSRLSYTTISTLGPG ::::::::::::::::::::::::::: CCDS77 PDEDPPTPSIASLSRLSYTTISTLGPG 430 440 >>CCDS81550.1 CCKBR gene_id:887|Hs108|chr11 (363 aa) initn: 2138 init1: 2138 opt: 2138 Z-score: 1918.1 bits: 363.8 E(32554): 1.6e-100 Smith-Waterman score: 2303; 81.2% identity (81.2% similar) in 447 aa overlap (1-447:1-363) 10 20 30 40 50 60 pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTR---------- 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF CCDS81 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL :::::::::::::::::::::::::::::::::::::::::::::: CCDS81 --------------GVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL 60 70 80 90 190 200 210 220 230 240 pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL 100 110 120 130 140 150 250 260 270 280 290 300 pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS 160 170 180 190 200 210 310 320 330 340 350 360 pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG 220 230 240 250 260 270 370 380 390 400 410 420 pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL 280 290 300 310 320 330 430 440 pF1KE0 PDEDPPTPSIASLSRLSYTTISTLGPG ::::::::::::::::::::::::::: CCDS81 PDEDPPTPSIASLSRLSYTTISTLGPG 340 350 360 >>CCDS3438.1 CCKAR gene_id:886|Hs108|chr4 (428 aa) initn: 1294 init1: 603 opt: 1243 Z-score: 1119.2 bits: 216.2 E(32554): 5.1e-56 Smith-Waterman score: 1313; 50.4% identity (73.8% similar) in 423 aa overlap (37-446:27-426) 10 20 30 40 50 60 pF1KE0 NRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSC-EPPRIRGAGTRELELAIRITLYAVIF : : . :: ..: . :..: ::..:: CCDS34 MDVVDSLLVNGSNITPPCELGLENETLFCLDQPR----PSKEWQPAVQILLYSLIF 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTV :.:: :: :.:.:: ..:.::::: ::::::::::.: . ::::.:.:::. ::::.. CCDS34 LLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 ICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLL .::...:.::.::::::..::::.::::.:::.:::.:::::.::: .::.::: :: . CCDS34 VCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 MVPYPVYTVVQPVGPRVLQ----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLI :.:::.:. . : : : :. ..:.: ..:::.::.:::.:: :::::: CCDS34 MTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLI 180 190 200 210 220 230 250 260 270 280 290 pF1KE0 SRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVG--EDSDGCYVQLPR : ::: :..:.... .... : .: : . : :::::::.: : CCDS34 SLELYQGIKFEASQKKSAKER-----------------KPSTTSSGKYEDSDGCYLQKTR 240 250 260 270 300 310 320 330 340 350 pF1KE0 SRPALELTALTAPGPGSGSR----PTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTW ::: :.. . . ..: . :.:.:::::.:::.::::::::::.:..:::.: CCDS34 PPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAW 280 290 300 310 320 330 360 370 380 390 400 410 pF1KE0 RAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRP--P ::.: .:.: :::.::::: ::::.:.::::..::::..::: . . : ::: : : CCDS34 RAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFP-CCPNPGPP 340 350 360 370 380 390 420 430 440 pF1KE0 RARPRALPDEDPPTPSIASLSRLSYTTISTLGPG :: .. .:. : . :::::.::. .:. : CCDS34 GARGEVGEEEEGGTTG-ASLSRFSYSHMSASVPPQ 400 410 420 >>CCDS3804.1 NPY5R gene_id:4889|Hs108|chr4 (445 aa) initn: 430 init1: 252 opt: 398 Z-score: 365.4 bits: 76.8 E(32554): 4.9e-14 Smith-Waterman score: 407; 25.6% identity (55.6% similar) in 410 aa overlap (58-408:45-442) 30 40 50 60 70 80 pF1KE0 LLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRT : ::. . :.. ::.::...: .: .: CCDS38 TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKT 20 30 40 50 60 70 90 100 110 120 130 140 pF1KE0 VTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVA ..: .. .:: ::.:... : :::: :. ..:: :.:. . .:. ::: :::: :.. CCDS38 TVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILIS 80 90 100 110 120 130 150 160 170 180 190 200 pF1KE0 IALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVY-TVVQ---PVGPRVL ::. :: : .:.. . : .:. .:...: :. . : ::. ..:. : .: CCDS38 IAIVRYHMIKHPISNNL--TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALL 140 150 160 170 180 190 210 220 230 240 250 pF1KE0 Q----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDS . ::. ::: : .... :::. ...: : ..:.. . : . :: :.. CCDS38 SSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGL-------SNK 200 210 220 230 240 260 270 280 290 300 pF1KE0 QSRVRNQGGLPGAVHQNGRCRPETGAVGEDS----------------DGCYVQLPRSRPA ..:.... . ..: . . :.. : . .: . :. ::. CCDS38 ENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPE-RPS 250 260 270 280 290 300 310 320 330 pF1KE0 LE----------------LTALTAPGPGSGS----RPTQA----KLLAKKRVVRM----- : :.. . :: . .: . .: .:. :.:. CCDS38 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSR 310 320 330 340 350 360 340 350 360 370 380 pF1KE0 -----LLVIVVLFFLCWLPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPL : .....: . :.:.. .. : :. ..: .. . . :::.. : :.::. CCDS38 SVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLV-YCICHLLGMMSCCLNPI 370 380 390 400 410 420 390 400 410 420 430 440 pF1KE0 VYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG .: :.. .. : : . .: CCDS38 LYGFLNNGIK-ADLVSLIHCLHM 430 440 >>CCDS4956.1 HCRTR2 gene_id:3062|Hs108|chr6 (444 aa) initn: 518 init1: 315 opt: 397 Z-score: 364.5 bits: 76.6 E(32554): 5.5e-14 Smith-Waterman score: 514; 28.3% identity (59.2% similar) in 375 aa overlap (50-409:51-383) 20 30 40 50 60 70 pF1KE0 SLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVL .: : .. :. : ..:.... ::.:. :.. CCDS49 LNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVL-IAGYIIVFVVALIGNVLVCVAV 30 40 50 60 70 80 90 100 110 120 130 pF1KE0 GLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVS ....::::: :...:...:.:....:.: ::. .. :..:: .::.. ::. :::: CCDS49 WKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVS 80 90 100 110 120 130 140 150 160 170 180 190 pF1KE0 VSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVG ::.:.: :::.:. :::.::. . .: ..: :: :..: ..:.: . . : CCDS49 VSVLTLSCIALDRWYAICHPLMFK--STAKRARNSIVIIWIVSCIIMIPQAIVMECSTVF 140 150 160 170 180 190 200 210 220 230 240 250 pF1KE0 PRVLQ-------CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFD : . . : .:: . . . . ..:. .. : .:..:: : :.:. CCDS49 PGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLW------ 200 210 220 230 240 250 260 270 280 290 300 310 pF1KE0 GDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAP :. : ..:.. . .: .: : :.: .: CCDS49 ----------CRQIPGTSSVVQR--KWKP-------------LQ-PVSQP-------RGP 260 270 320 330 340 350 360 pF1KE0 GPGSGSRPTQA-----KLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAH--- : . :: . . .. :.....:::......: .:.::. :. . : :: CCDS49 GQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTED 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 RALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDED : : ..: : : ::.. .::..: :. .::. . . :: CCDS49 RETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGR 340 350 360 370 380 390 430 440 pF1KE0 PPTPSIASLSRLSYTTISTLGPG CCDS49 TSTESRKSLTTQISNFDNISKLSEQVVLTSISTLPAANGAGPLQNW 400 410 420 430 440 >>CCDS34089.1 NPY1R gene_id:4886|Hs108|chr4 (384 aa) initn: 408 init1: 278 opt: 369 Z-score: 340.2 bits: 71.9 E(32554): 1.2e-12 Smith-Waterman score: 405; 27.0% identity (53.3% similar) in 411 aa overlap (52-446:35-369) 30 40 50 60 70 pF1KE0 CRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL---YAVIFLMSVGGNMLIIVV : ::. .:: :.......:.::. .:.. CCDS34 LFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIII 10 20 30 40 50 60 80 90 100 110 120 130 pF1KE0 LGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSV . ....:.::: ....:. ::::.:. :.:::.. .:: ..:: ..:: ... ::. CCDS34 ILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSI 70 80 90 100 110 120 140 150 160 170 180 190 pF1KE0 SVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVAT-WLLSGLLMVPYPVYTVV-- .:: .::: ::.::.. : : : :. .. : : .:. :.:. .:. .: :. CCDS34 TVSIFSLVLIAVERHQLIINP---RGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTD 130 140 150 160 170 180 200 210 220 230 240 pF1KE0 QPVGPRVLQ-------CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLG .: .:. : ..:: : ....:::.: .: : . . : ..:. CCDS34 EPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICY----FKIYI- 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 LRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTA :.. .... ...: :: CCDS34 -------------RLKRRNNMMDKMRDNKYRSSET------------------------- 240 250 310 320 330 340 350 360 pF1KE0 LTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALS ::. ::: ::: : .::::. :: .:: : CCDS34 --------------------KRINIMLLSIVVAFAVCWLPLTIFNT--VFDWNHQIIATC 260 270 280 290 370 380 390 400 410 420 pF1KE0 GAPISFI--HLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPP . . :. :: .. :.::::. : :... : : :. : :.: :.: CCDS34 NHNLLFLLCHLTAMISTCVNPIFYGFLNKNF-QRDLQFFFNFCDF--RSR-----DDDYE 300 310 320 330 340 430 440 pF1KE0 TPSIASL-SRLSYTTISTLGPG : ..... . .: :... .: CCDS34 TIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI 350 360 370 380 >>CCDS3791.1 NPY2R gene_id:4887|Hs108|chr4 (381 aa) initn: 391 init1: 262 opt: 368 Z-score: 339.4 bits: 71.8 E(32554): 1.4e-12 Smith-Waterman score: 376; 25.6% identity (55.2% similar) in 386 aa overlap (35-411:30-345) 10 20 30 40 50 60 pF1KE0 KLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEP-PRIRGAGTRELELAIRITL-YA :.: .: :.. . :. .:. . . : : CCDS37 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDS-TKLIEVQVVLILAYC 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 VIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIF :.:..: :: :.: :. . .::::: :. .:::.:::. . :.:::: .::: . . CCDS37 SIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKM 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 GTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLS : :.:. : : .:..:.:::..:..:::.:. : :.... .. . .: .: .: CCDS37 GPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKI--SKRISFLIIGLAWGIS 120 130 140 150 160 170 190 200 210 220 230 pF1KE0 GLLMVPYPV---YTVVQPVGP-RVLQCVHRWPSAR--VRQT-WSVLLLLLLFFIPGVVMA .:: : . :.... . ... :...::. . . : .:. ::.:. .: ... CCDS37 ALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIIS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 VAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYV .: : :...:. . :::.... . : CCDS37 FSYTRI------------------WSKLKNHVS-PGAANDHYHQR--------------- 240 250 260 300 310 320 330 340 350 pF1KE0 QLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTW ......::. .::.: . :::... . CCDS37 --------------------------------RQKTTKMLVCVVVVFAVSWLPLHAFQLA 270 280 290 360 370 380 390 400 410 pF1KE0 RAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRA .:. .. .:.... :. .:::.: .:. .:.: : . :: : CCDS37 VDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFL-SAFRCEQRLDAI 300 310 320 330 340 420 430 440 pF1KE0 RPRALPDEDPPTPSIASLSRLSYTTISTLGPG CCDS37 HSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV 350 360 370 380 >>CCDS344.1 HCRTR1 gene_id:3061|Hs108|chr1 (425 aa) initn: 444 init1: 289 opt: 368 Z-score: 338.9 bits: 71.8 E(32554): 1.5e-12 Smith-Waterman score: 490; 28.4% identity (58.9% similar) in 401 aa overlap (56-444:48-411) 30 40 50 60 70 80 pF1KE0 APLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRL . :. :...:.... :: :. ... .... CCDS34 REPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHM 20 30 40 50 60 70 90 100 110 120 130 140 pF1KE0 RTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSL ::::: :...:...:.:... :.: .:: .. ...:: ..::.. ::..:::::..:.: CCDS34 RTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTL 80 90 100 110 120 130 150 160 170 180 190 200 pF1KE0 VAIALERYSAICRPLQARVWQTRSHAAR-VIVATWLLSGLLMVPYPVYTVVQPVGPRVLQ :::.:. :::.:: .... .. :: :.. : .: .::: . . : :.. . CCDS34 SFIALDRWYAICHPL---LFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELAN 140 150 160 170 180 190 210 220 230 240 250 pF1KE0 -------CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDS : .:: . . . .... .. : .::.:: : :.:. : .. : ... CCDS34 RTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLW-GRQIPGTTSA 200 210 220 230 240 250 260 270 280 290 300 310 pF1KE0 DSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSG ::: :. : : : : :: . ::.: : . CCDS34 ----LVRNWKR-PS--DQLGDL--EQGLSGEPQ-------PRARAFLAEVK--------- 260 270 280 320 330 340 350 360 370 pF1KE0 SRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG---PGAHRALSGAPISF .. :......::.:....: ::.::. :. . : .. : : ..: CCDS34 ------QMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTF 290 300 310 320 330 340 380 390 400 410 420 430 pF1KE0 IHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDP-PTPSIASL : : ::.. .::..: :. .::. ... :: : . .: .: . : :: CCDS34 SHWLVYANSAANPIIYNFLSGKFREQ-FKAAFSCC-LPGLGPCGSLKAPSPRSSASHKSL 350 360 370 380 390 400 440 pF1KE0 SRLSYTTISTLGPG : : .:: . CCDS34 SLQSRCSISKISEHVVLTSVTTVLP 410 420 >>CCDS47004.1 ADRA2C gene_id:152|Hs108|chr4 (462 aa) initn: 338 init1: 278 opt: 365 Z-score: 335.8 bits: 71.4 E(32554): 2.2e-12 Smith-Waterman score: 402; 26.7% identity (52.9% similar) in 446 aa overlap (16-400:17-447) 10 20 30 40 50 pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCE---PPRIRGAGTRELELAI ::.:: :: .:..:.: : ::: . .. :: CCDS47 MASPALAAALAVAAAAGPNAS----GAGERGSGGVANASGASWGPPRGQYSAGAVAGLAA 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 RITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNL .. . ..: .: ::.:..... :: ::. : ::.::: .:.:.:. :::.: .: CCDS47 -VVGFLIVF--TVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANEL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 MGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIV :. . :: : : . : . . : . : ::.:.:: .. . .. . .: .. .:: CCDS47 MAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 ATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLL-LFFIPGVVMA :.::.:... : : :: : :: . .:: .: . :: : ..:. CCDS47 AVWLISAVISFPPLVSLYRQPDGAAYPQC------GLNDETWYILSSCIGSFFAPCLIMG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 VAYGLISRELYLGLRFDGDSDS----DSQSRVRNQG-GLPGAVHQNGRCRPETGAVGEDS ..:. : : : : ... . :. : . ..: : ... .::.: : . : : CCDS47 LVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDE 230 240 250 260 270 280 300 310 320 pF1KE0 DGCYVQLPRSRPAL---------------------------ELTALTAP-GPGSGSRPTQ .. .. : : :: : :::: .:: :.: .. CCDS47 SSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSR 290 300 310 320 330 340 330 340 350 pF1KE0 AK------LLAKKRVVR------------------MLLVIVVLFFLCWLPVYSANTWRAF :. .:...: .: .: :.. .: :::.: . . . .. CCDS47 ASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGI 350 360 370 380 390 400 360 370 380 390 400 410 pF1KE0 DGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPR . . . : ..:. ..: .. .::..: ... ::.. CCDS47 CREACQ--VPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ 410 420 430 440 450 460 420 430 440 pF1KE0 ALPDEDPPTPSIASLSRLSYTTISTLGPG >>CCDS13958.1 GALR3 gene_id:8484|Hs108|chr22 (368 aa) initn: 404 init1: 248 opt: 358 Z-score: 330.6 bits: 70.1 E(32554): 4.3e-12 Smith-Waterman score: 376; 28.0% identity (51.9% similar) in 422 aa overlap (36-447:6-350) 10 20 30 40 50 60 pF1KE0 LNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIF :.: . : :: .:. . ..:.:: CCDS13 MADAQNISLDSPGSVGA------VAVPV-VFALIF 10 20 70 80 90 100 110 120 pF1KE0 LMSVGGNMLIIVVL---GLS--RRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF :... :: :...:: : : .. ..:. :.:.:::.:: . . :.:: . .. CCDS13 LLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL .::...:::: :. ... .:...:.:....:: :. .::..:. .: .: .. .:: CCDS13 LFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWL 90 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL :..:. .:: : . : : :: : .:: :.. .: . ...: .:...::: CCDS13 LAALFSAPYLSYYGTVRYGALEL-CVPAWEDAR-RRALDVATFAAGYLLPVAVVSLAYGR 150 160 170 180 190 200 250 260 270 280 290 300 pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS : :. .::: CCDS13 TLRFLW-------------------------------------AAVG------------- 210 310 320 330 340 350 360 pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG :: :. ..:. : :. : .:....:. ::: : . : . : CCDS13 -PA-------------GAAAAEARRRATGRAGRAMLAVAALYALCWGP-HHALILCFWYG 220 230 240 250 260 370 380 390 400 410 pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQAC--LETCARCCPRPPRARPR : . : : :.::..:.::::: . :.:: : :.: : ::: : CCDS13 RFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGR--RRRHRAR-R 270 280 290 300 310 420 430 440 pF1KE0 ALPDEDPPT---PSIASLSRLSYTTISTLGPG :: : . :. . .: : .. : : CCDS13 ALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE 320 330 340 350 360 447 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:17:36 2016 done: Sat Nov 5 18:17:36 2016 Total Scan time: 3.140 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]