FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0638, 447 aa
1>>>pF1KE0638 447 - 447 aa - 447 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1511+/-0.000702; mu= 20.5423+/- 0.043
mean_var=125.7394+/-40.454, 0's: 0 Z-trim(112.9): 278 B-trim: 1545 in 2/50
Lambda= 0.114377
statistics sampled from 12968 (13602) to 12968 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.418), width: 16
Scan time: 3.140
The best scores are: opt bits E(32554)
CCDS7761.1 CCKBR gene_id:887|Hs108|chr11 ( 447) 2993 505.0 6.2e-143
CCDS81550.1 CCKBR gene_id:887|Hs108|chr11 ( 363) 2138 363.8 1.6e-100
CCDS3438.1 CCKAR gene_id:886|Hs108|chr4 ( 428) 1243 216.2 5.1e-56
CCDS3804.1 NPY5R gene_id:4889|Hs108|chr4 ( 445) 398 76.8 4.9e-14
CCDS4956.1 HCRTR2 gene_id:3062|Hs108|chr6 ( 444) 397 76.6 5.5e-14
CCDS34089.1 NPY1R gene_id:4886|Hs108|chr4 ( 384) 369 71.9 1.2e-12
CCDS3791.1 NPY2R gene_id:4887|Hs108|chr4 ( 381) 368 71.8 1.4e-12
CCDS344.1 HCRTR1 gene_id:3061|Hs108|chr1 ( 425) 368 71.8 1.5e-12
CCDS47004.1 ADRA2C gene_id:152|Hs108|chr4 ( 462) 365 71.4 2.2e-12
CCDS13958.1 GALR3 gene_id:8484|Hs108|chr22 ( 368) 358 70.1 4.3e-12
CCDS3719.1 QRFPR gene_id:84109|Hs108|chr4 ( 431) 357 70.0 5.3e-12
CCDS329.1 OPRD1 gene_id:4985|Hs108|chr1 ( 372) 350 68.8 1.1e-11
CCDS13556.1 OPRL1 gene_id:4987|Hs108|chr20 ( 370) 342 67.4 2.7e-11
CCDS11739.1 GALR2 gene_id:8811|Hs108|chr17 ( 387) 339 67.0 3.9e-11
CCDS53539.1 NPFFR1 gene_id:64106|Hs108|chr10 ( 430) 337 66.7 5.2e-11
CCDS6311.1 TRHR gene_id:7201|Hs108|chr8 ( 398) 335 66.3 6.2e-11
CCDS42856.1 SSTR4 gene_id:6754|Hs108|chr20 ( 388) 334 66.2 6.9e-11
CCDS3552.1 NPFFR2 gene_id:10886|Hs108|chr4 ( 420) 332 65.9 9.1e-11
CCDS47072.1 NPFFR2 gene_id:10886|Hs108|chr4 ( 423) 332 65.9 9.1e-11
CCDS55069.1 OPRM1 gene_id:4988|Hs108|chr6 ( 389) 331 65.7 9.7e-11
CCDS47508.1 OPRM1 gene_id:4988|Hs108|chr6 ( 392) 331 65.7 9.8e-11
CCDS47505.1 OPRM1 gene_id:4988|Hs108|chr6 ( 397) 331 65.7 9.8e-11
CCDS55070.1 OPRM1 gene_id:4988|Hs108|chr6 ( 400) 331 65.7 9.9e-11
CCDS47506.1 OPRM1 gene_id:4988|Hs108|chr6 ( 403) 331 65.7 9.9e-11
CCDS47504.1 OPRM1 gene_id:4988|Hs108|chr6 ( 406) 331 65.7 1e-10
>>CCDS7761.1 CCKBR gene_id:887|Hs108|chr11 (447 aa)
initn: 2993 init1: 2993 opt: 2993 Z-score: 2679.6 bits: 505.0 E(32554): 6.2e-143
Smith-Waterman score: 2993; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
370 380 390 400 410 420
430 440
pF1KE0 PDEDPPTPSIASLSRLSYTTISTLGPG
:::::::::::::::::::::::::::
CCDS77 PDEDPPTPSIASLSRLSYTTISTLGPG
430 440
>>CCDS81550.1 CCKBR gene_id:887|Hs108|chr11 (363 aa)
initn: 2138 init1: 2138 opt: 2138 Z-score: 1918.1 bits: 363.8 E(32554): 1.6e-100
Smith-Waterman score: 2303; 81.2% identity (81.2% similar) in 447 aa overlap (1-447:1-363)
10 20 30 40 50 60
pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTR----------
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
CCDS81 ------------------------------------------------------------
130 140 150 160 170 180
pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 --------------GVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
60 70 80 90
190 200 210 220 230 240
pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
280 290 300 310 320 330
430 440
pF1KE0 PDEDPPTPSIASLSRLSYTTISTLGPG
:::::::::::::::::::::::::::
CCDS81 PDEDPPTPSIASLSRLSYTTISTLGPG
340 350 360
>>CCDS3438.1 CCKAR gene_id:886|Hs108|chr4 (428 aa)
initn: 1294 init1: 603 opt: 1243 Z-score: 1119.2 bits: 216.2 E(32554): 5.1e-56
Smith-Waterman score: 1313; 50.4% identity (73.8% similar) in 423 aa overlap (37-446:27-426)
10 20 30 40 50 60
pF1KE0 NRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSC-EPPRIRGAGTRELELAIRITLYAVIF
: : . :: ..: . :..: ::..::
CCDS34 MDVVDSLLVNGSNITPPCELGLENETLFCLDQPR----PSKEWQPAVQILLYSLIF
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 LMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTV
:.:: :: :.:.:: ..:.::::: ::::::::::.: . ::::.:.:::. ::::..
CCDS34 LLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLL
.::...:.::.::::::..::::.::::.:::.:::.:::::.::: .::.::: :: .
CCDS34 VCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 MVPYPVYTVVQPVGPRVLQ----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLI
:.:::.:. . : : : :. ..:.: ..:::.::.:::.:: ::::::
CCDS34 MTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLI
180 190 200 210 220 230
250 260 270 280 290
pF1KE0 SRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVG--EDSDGCYVQLPR
: ::: :..:.... .... : .: : . : :::::::.: :
CCDS34 SLELYQGIKFEASQKKSAKER-----------------KPSTTSSGKYEDSDGCYLQKTR
240 250 260 270
300 310 320 330 340 350
pF1KE0 SRPALELTALTAPGPGSGSR----PTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTW
::: :.. . . ..: . :.:.:::::.:::.::::::::::.:..:::.:
CCDS34 PPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAW
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE0 RAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRP--P
::.: .:.: :::.::::: ::::.:.::::..::::..::: . . : ::: : :
CCDS34 RAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFP-CCPNPGPP
340 350 360 370 380 390
420 430 440
pF1KE0 RARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
:: .. .:. : . :::::.::. .:. :
CCDS34 GARGEVGEEEEGGTTG-ASLSRFSYSHMSASVPPQ
400 410 420
>>CCDS3804.1 NPY5R gene_id:4889|Hs108|chr4 (445 aa)
initn: 430 init1: 252 opt: 398 Z-score: 365.4 bits: 76.8 E(32554): 4.9e-14
Smith-Waterman score: 407; 25.6% identity (55.6% similar) in 410 aa overlap (58-408:45-442)
30 40 50 60 70 80
pF1KE0 LLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRT
: ::. . :.. ::.::...: .: .:
CCDS38 TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 VTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVA
..: .. .:: ::.:... : :::: :. ..:: :.:. . .:. ::: :::: :..
CCDS38 TVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILIS
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE0 IALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVY-TVVQ---PVGPRVL
::. :: : .:.. . : .:. .:...: :. . : ::. ..:. : .:
CCDS38 IAIVRYHMIKHPISNNL--TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALL
140 150 160 170 180 190
210 220 230 240 250
pF1KE0 Q----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDS
. ::. ::: : .... :::. ...: : ..:.. . : . :: :..
CCDS38 SSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGL-------SNK
200 210 220 230 240
260 270 280 290 300
pF1KE0 QSRVRNQGGLPGAVHQNGRCRPETGAVGEDS----------------DGCYVQLPRSRPA
..:.... . ..: . . :.. : . .: . :. ::.
CCDS38 ENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPE-RPS
250 260 270 280 290 300
310 320 330
pF1KE0 LE----------------LTALTAPGPGSGS----RPTQA----KLLAKKRVVRM-----
: :.. . :: . .: . .: .:. :.:.
CCDS38 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSR
310 320 330 340 350 360
340 350 360 370 380
pF1KE0 -----LLVIVVLFFLCWLPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPL
: .....: . :.:.. .. : :. ..: .. . . :::.. : :.::.
CCDS38 SVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLV-YCICHLLGMMSCCLNPI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE0 VYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
.: :.. .. : : . .:
CCDS38 LYGFLNNGIK-ADLVSLIHCLHM
430 440
>>CCDS4956.1 HCRTR2 gene_id:3062|Hs108|chr6 (444 aa)
initn: 518 init1: 315 opt: 397 Z-score: 364.5 bits: 76.6 E(32554): 5.5e-14
Smith-Waterman score: 514; 28.3% identity (59.2% similar) in 375 aa overlap (50-409:51-383)
20 30 40 50 60 70
pF1KE0 SLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVL
.: : .. :. : ..:.... ::.:. :..
CCDS49 LNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVL-IAGYIIVFVVALIGNVLVCVAV
30 40 50 60 70
80 90 100 110 120 130
pF1KE0 GLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVS
....::::: :...:...:.:....:.: ::. .. :..:: .::.. ::. ::::
CCDS49 WKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVS
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 VSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVG
::.:.: :::.:. :::.::. . .: ..: :: :..: ..:.: . . :
CCDS49 VSVLTLSCIALDRWYAICHPLMFK--STAKRARNSIVIIWIVSCIIMIPQAIVMECSTVF
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 PRVLQ-------CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFD
: . . : .:: . . . . ..:. .. : .:..:: : :.:.
CCDS49 PGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLW------
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 GDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAP
:. : ..:.. . .: .: : :.: .:
CCDS49 ----------CRQIPGTSSVVQR--KWKP-------------LQ-PVSQP-------RGP
260 270
320 330 340 350 360
pF1KE0 GPGSGSRPTQA-----KLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAH---
: . :: . . .. :.....:::......: .:.::. :. . : ::
CCDS49 GQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTED
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 RALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDED
: : ..: : : ::.. .::..: :. .::. . . ::
CCDS49 RETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGR
340 350 360 370 380 390
430 440
pF1KE0 PPTPSIASLSRLSYTTISTLGPG
CCDS49 TSTESRKSLTTQISNFDNISKLSEQVVLTSISTLPAANGAGPLQNW
400 410 420 430 440
>>CCDS34089.1 NPY1R gene_id:4886|Hs108|chr4 (384 aa)
initn: 408 init1: 278 opt: 369 Z-score: 340.2 bits: 71.9 E(32554): 1.2e-12
Smith-Waterman score: 405; 27.0% identity (53.3% similar) in 411 aa overlap (52-446:35-369)
30 40 50 60 70
pF1KE0 CRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL---YAVIFLMSVGGNMLIIVV
: ::. .:: :.......:.::. .:..
CCDS34 LFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIII
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE0 LGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSV
. ....:.::: ....:. ::::.:. :.:::.. .:: ..:: ..:: ... ::.
CCDS34 ILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSI
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE0 SVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVAT-WLLSGLLMVPYPVYTVV--
.:: .::: ::.::.. : : : :. .. : : .:. :.:. .:. .: :.
CCDS34 TVSIFSLVLIAVERHQLIINP---RGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTD
130 140 150 160 170 180
200 210 220 230 240
pF1KE0 QPVGPRVLQ-------CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLG
.: .:. : ..:: : ....:::.: .: : . . : ..:.
CCDS34 EPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICY----FKIYI-
190 200 210 220 230
250 260 270 280 290 300
pF1KE0 LRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTA
:.. .... ...: ::
CCDS34 -------------RLKRRNNMMDKMRDNKYRSSET-------------------------
240 250
310 320 330 340 350 360
pF1KE0 LTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALS
::. ::: ::: : .::::. :: .:: :
CCDS34 --------------------KRINIMLLSIVVAFAVCWLPLTIFNT--VFDWNHQIIATC
260 270 280 290
370 380 390 400 410 420
pF1KE0 GAPISFI--HLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPP
. . :. :: .. :.::::. : :... : : :. : :.: :.:
CCDS34 NHNLLFLLCHLTAMISTCVNPIFYGFLNKNF-QRDLQFFFNFCDF--RSR-----DDDYE
300 310 320 330 340
430 440
pF1KE0 TPSIASL-SRLSYTTISTLGPG
: ..... . .: :... .:
CCDS34 TIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
350 360 370 380
>>CCDS3791.1 NPY2R gene_id:4887|Hs108|chr4 (381 aa)
initn: 391 init1: 262 opt: 368 Z-score: 339.4 bits: 71.8 E(32554): 1.4e-12
Smith-Waterman score: 376; 25.6% identity (55.2% similar) in 386 aa overlap (35-411:30-345)
10 20 30 40 50 60
pF1KE0 KLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEP-PRIRGAGTRELELAIRITL-YA
:.: .: :.. . :. .:. . . : :
CCDS37 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDS-TKLIEVQVVLILAYC
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIF
:.:..: :: :.: :. . .::::: :. .:::.:::. . :.:::: .::: . .
CCDS37 SIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 GTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLS
: :.:. : : .:..:.:::..:..:::.:. : :.... .. . .: .: .:
CCDS37 GPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKI--SKRISFLIIGLAWGIS
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 GLLMVPYPV---YTVVQPVGP-RVLQCVHRWPSAR--VRQT-WSVLLLLLLFFIPGVVMA
.:: : . :.... . ... :...::. . . : .:. ::.:. .: ...
CCDS37 ALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIIS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 VAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYV
.: : :...:. . :::.... . :
CCDS37 FSYTRI------------------WSKLKNHVS-PGAANDHYHQR---------------
240 250 260
300 310 320 330 340 350
pF1KE0 QLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTW
......::. .::.: . :::... .
CCDS37 --------------------------------RQKTTKMLVCVVVVFAVSWLPLHAFQLA
270 280 290
360 370 380 390 400 410
pF1KE0 RAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRA
.:. .. .:.... :. .:::.: .:. .:.: : . :: :
CCDS37 VDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFL-SAFRCEQRLDAI
300 310 320 330 340
420 430 440
pF1KE0 RPRALPDEDPPTPSIASLSRLSYTTISTLGPG
CCDS37 HSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
350 360 370 380
>>CCDS344.1 HCRTR1 gene_id:3061|Hs108|chr1 (425 aa)
initn: 444 init1: 289 opt: 368 Z-score: 338.9 bits: 71.8 E(32554): 1.5e-12
Smith-Waterman score: 490; 28.4% identity (58.9% similar) in 401 aa overlap (56-444:48-411)
30 40 50 60 70 80
pF1KE0 APLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRL
. :. :...:.... :: :. ... ....
CCDS34 REPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHM
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 RTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSL
::::: :...:...:.:... :.: .:: .. ...:: ..::.. ::..:::::..:.:
CCDS34 RTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTL
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE0 VAIALERYSAICRPLQARVWQTRSHAAR-VIVATWLLSGLLMVPYPVYTVVQPVGPRVLQ
:::.:. :::.:: .... .. :: :.. : .: .::: . . : :.. .
CCDS34 SFIALDRWYAICHPL---LFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELAN
140 150 160 170 180 190
210 220 230 240 250
pF1KE0 -------CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDS
: .:: . . . .... .. : .::.:: : :.:. : .. : ...
CCDS34 RTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLW-GRQIPGTTSA
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 DSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSG
::: :. : : : : :: . ::.: : .
CCDS34 ----LVRNWKR-PS--DQLGDL--EQGLSGEPQ-------PRARAFLAEVK---------
260 270 280
320 330 340 350 360 370
pF1KE0 SRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG---PGAHRALSGAPISF
.. :......::.:....: ::.::. :. . : .. : : ..:
CCDS34 ------QMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTF
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE0 IHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDP-PTPSIASL
: : ::.. .::..: :. .::. ... :: : . .: .: . : ::
CCDS34 SHWLVYANSAANPIIYNFLSGKFREQ-FKAAFSCC-LPGLGPCGSLKAPSPRSSASHKSL
350 360 370 380 390 400
440
pF1KE0 SRLSYTTISTLGPG
: : .:: .
CCDS34 SLQSRCSISKISEHVVLTSVTTVLP
410 420
>>CCDS47004.1 ADRA2C gene_id:152|Hs108|chr4 (462 aa)
initn: 338 init1: 278 opt: 365 Z-score: 335.8 bits: 71.4 E(32554): 2.2e-12
Smith-Waterman score: 402; 26.7% identity (52.9% similar) in 446 aa overlap (16-400:17-447)
10 20 30 40 50
pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCE---PPRIRGAGTRELELAI
::.:: :: .:..:.: : ::: . .. ::
CCDS47 MASPALAAALAVAAAAGPNAS----GAGERGSGGVANASGASWGPPRGQYSAGAVAGLAA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 RITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNL
.. . ..: .: ::.:..... :: ::. : ::.::: .:.:.:. :::.: .:
CCDS47 -VVGFLIVF--TVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANEL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 MGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIV
:. . :: : : . : . . : . : ::.:.:: .. . .. . .: .. .::
CCDS47 MAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 ATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLL-LFFIPGVVMA
:.::.:... : : :: : :: . .:: .: . :: : ..:.
CCDS47 AVWLISAVISFPPLVSLYRQPDGAAYPQC------GLNDETWYILSSCIGSFFAPCLIMG
180 190 200 210 220
240 250 260 270 280 290
pF1KE0 VAYGLISRELYLGLRFDGDSDS----DSQSRVRNQG-GLPGAVHQNGRCRPETGAVGEDS
..:. : : : : ... . :. : . ..: : ... .::.: : . : :
CCDS47 LVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDE
230 240 250 260 270 280
300 310 320
pF1KE0 DGCYVQLPRSRPAL---------------------------ELTALTAP-GPGSGSRPTQ
.. .. : : :: : :::: .:: :.: ..
CCDS47 SSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSR
290 300 310 320 330 340
330 340 350
pF1KE0 AK------LLAKKRVVR------------------MLLVIVVLFFLCWLPVYSANTWRAF
:. .:...: .: .: :.. .: :::.: . . . ..
CCDS47 ASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGI
350 360 370 380 390 400
360 370 380 390 400 410
pF1KE0 DGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPR
. . . : ..:. ..: .. .::..: ... ::..
CCDS47 CREACQ--VPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
410 420 430 440 450 460
420 430 440
pF1KE0 ALPDEDPPTPSIASLSRLSYTTISTLGPG
>>CCDS13958.1 GALR3 gene_id:8484|Hs108|chr22 (368 aa)
initn: 404 init1: 248 opt: 358 Z-score: 330.6 bits: 70.1 E(32554): 4.3e-12
Smith-Waterman score: 376; 28.0% identity (51.9% similar) in 422 aa overlap (36-447:6-350)
10 20 30 40 50 60
pF1KE0 LNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIF
:.: . : :: .:. . ..:.::
CCDS13 MADAQNISLDSPGSVGA------VAVPV-VFALIF
10 20
70 80 90 100 110 120
pF1KE0 LMSVGGNMLIIVVL---GLS--RRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
:... :: :...:: : : .. ..:. :.:.:::.:: . . :.:: . ..
CCDS13 LLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAW
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
.::...:::: :. ... .:...:.:....:: :. .::..:. .: .: .. .::
CCDS13 LFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
:..:. .:: : . : : :: : .:: :.. .: . ...: .:...:::
CCDS13 LAALFSAPYLSYYGTVRYGALEL-CVPAWEDAR-RRALDVATFAAGYLLPVAVVSLAYGR
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
: :. .:::
CCDS13 TLRFLW-------------------------------------AAVG-------------
210
310 320 330 340 350 360
pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
:: :. ..:. : :. : .:....:. ::: : . : . :
CCDS13 -PA-------------GAAAAEARRRATGRAGRAMLAVAALYALCWGP-HHALILCFWYG
220 230 240 250 260
370 380 390 400 410
pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQAC--LETCARCCPRPPRARPR
: . : : :.::..:.::::: . :.:: : :.: : ::: :
CCDS13 RFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGR--RRRHRAR-R
270 280 290 300 310
420 430 440
pF1KE0 ALPDEDPPT---PSIASLSRLSYTTISTLGPG
:: : . :. . .: : .. : :
CCDS13 ALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
320 330 340 350 360
447 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:17:36 2016 done: Sat Nov 5 18:17:36 2016
Total Scan time: 3.140 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]