FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0638, 447 aa
1>>>pF1KE0638 447 - 447 aa - 447 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8289+/-0.000302; mu= 22.4388+/- 0.019
mean_var=96.5483+/-21.914, 0's: 0 Z-trim(119.4): 632 B-trim: 2993 in 2/53
Lambda= 0.130527
statistics sampled from 32715 (33490) to 32715 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.393), width: 16
Scan time: 10.650
The best scores are: opt bits E(85289)
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 2993 573.6 3.6e-163
XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cho ( 381) 2560 492.0 1.1e-138
NP_001304958 (OMIM: 118445) gastrin/cholecystokini ( 363) 2138 412.5 9.2e-115
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 1760 341.5 3.1e-93
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 1243 244.1 5.5e-64
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 398 85.0 4.5e-16
NP_006165 (OMIM: 602001) neuropeptide Y receptor t ( 445) 398 85.0 4.5e-16
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445) 398 85.0 4.5e-16
XP_011530319 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 398 85.0 4.5e-16
NP_001304021 (OMIM: 602001) neuropeptide Y recepto ( 445) 398 85.0 4.5e-16
XP_016863744 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 398 85.0 4.6e-16
XP_016863745 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 398 85.0 4.6e-16
XP_011530317 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 398 85.0 4.6e-16
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 397 84.8 5.1e-16
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 397 84.8 5.3e-16
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 369 79.4 1.8e-14
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 369 79.4 1.8e-14
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 369 79.4 1.8e-14
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 368 79.2 2.1e-14
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 368 79.2 2.1e-14
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 368 79.2 2.1e-14
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 368 79.2 2.1e-14
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 368 79.3 2.2e-14
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 368 79.3 2.2e-14
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 368 79.3 2.2e-14
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 365 78.8 3.4e-14
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 358 77.3 7.4e-14
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 357 77.2 9.3e-14
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 356 77.0 9.6e-14
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 350 75.8 2.1e-13
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 342 74.3 6e-13
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 342 74.3 6e-13
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 342 74.3 6e-13
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 342 74.3 6e-13
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 342 74.3 6.2e-13
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 342 74.3 6.2e-13
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 342 74.3 6.2e-13
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 342 74.4 6.3e-13
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 339 73.8 9.1e-13
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 337 73.5 1.3e-12
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269) 334 72.6 1.4e-12
XP_011515565 (OMIM: 188545) PREDICTED: thyrotropin ( 398) 335 73.0 1.6e-12
NP_003292 (OMIM: 188545) thyrotropin-releasing hor ( 398) 335 73.0 1.6e-12
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 334 72.8 1.8e-12
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 332 72.4 2.2e-12
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 332 72.4 2.2e-12
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 332 72.5 2.4e-12
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 332 72.5 2.4e-12
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 331 72.3 2.6e-12
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 331 72.3 2.6e-12
>>NP_795344 (OMIM: 118445) gastrin/cholecystokinin type (447 aa)
initn: 2993 init1: 2993 opt: 2993 Z-score: 3050.5 bits: 573.6 E(85289): 3.6e-163
Smith-Waterman score: 2993; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
370 380 390 400 410 420
430 440
pF1KE0 PDEDPPTPSIASLSRLSYTTISTLGPG
:::::::::::::::::::::::::::
NP_795 PDEDPPTPSIASLSRLSYTTISTLGPG
430 440
>>XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cholecy (381 aa)
initn: 2560 init1: 2560 opt: 2560 Z-score: 2610.6 bits: 492.0 E(85289): 1.1e-138
Smith-Waterman score: 2560; 100.0% identity (100.0% similar) in 381 aa overlap (67-447:1-381)
40 50 60 70 80 90
pF1KE0 LSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSL
::::::::::::::::::::::::::::::
XP_016 MSVGGNMLIIVVLGLSRRLRTVTNAFLLSL
10 20 30
100 110 120 130 140 150
pF1KE0 AVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 CRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQ
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 TWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQN
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 GRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 VIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRR
280 290 300 310 320 330
400 410 420 430 440
pF1KE0 FRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
340 350 360 370 380
>>NP_001304958 (OMIM: 118445) gastrin/cholecystokinin ty (363 aa)
initn: 2138 init1: 2138 opt: 2138 Z-score: 2181.4 bits: 412.5 E(85289): 9.2e-115
Smith-Waterman score: 2303; 81.2% identity (81.2% similar) in 447 aa overlap (1-447:1-363)
10 20 30 40 50 60
pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTR----------
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
NP_001 ------------------------------------------------------------
130 140 150 160 170 180
pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------GVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
60 70 80 90
190 200 210 220 230 240
pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE0 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
280 290 300 310 320 330
430 440
pF1KE0 PDEDPPTPSIASLSRLSYTTISTLGPG
:::::::::::::::::::::::::::
NP_001 PDEDPPTPSIASLSRLSYTTISTLGPG
340 350 360
>>XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cholecy (516 aa)
initn: 1760 init1: 1760 opt: 1760 Z-score: 1794.9 bits: 341.5 E(85289): 3.1e-93
Smith-Waterman score: 2594; 85.6% identity (85.6% similar) in 479 aa overlap (1-410:1-479)
10 20 30 40 50 60
pF1KE0 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
190 200 210 220 230 240
250 260 270
pF1KE0 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPG-----------------------------
:::::::::::::::::::::::::::::::
XP_005 ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGGAGPREQNLGEAELWRATGPAGVGGTEMK
250 260 270 280 290 300
280 290
pF1KE0 ----------------------------------------AVHQNGRCRPETGAVGEDSD
::::::::::::::::::::
XP_005 VRVRRKLEMELSWERRSGGDWAGDWGDSPFSLTAHPLCSGAVHQNGRCRPETGAVGEDSD
310 320 330 340 350 360
300 310 320 330 340 350
pF1KE0 GCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYS
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE0 ANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPR
430 440 450 460 470 480
420 430 440
pF1KE0 PPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
XP_005 PPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
490 500 510
>--
initn: 251 init1: 251 opt: 251 Z-score: 259.2 bits: 57.4 E(85289): 1.1e-07
Smith-Waterman score: 251; 100.0% identity (100.0% similar) in 37 aa overlap (411-447:480-516)
390 400 410 420 430 440
pF1KE0 ASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTT
::::::::::::::::::::::::::::::
XP_005 ASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTT
450 460 470 480 490 500
pF1KE0 ISTLGPG
:::::::
XP_005 ISTLGPG
510
>>NP_000721 (OMIM: 118444) cholecystokinin receptor type (428 aa)
initn: 1294 init1: 603 opt: 1243 Z-score: 1269.7 bits: 244.1 E(85289): 5.5e-64
Smith-Waterman score: 1313; 50.4% identity (73.8% similar) in 423 aa overlap (37-446:27-426)
10 20 30 40 50 60
pF1KE0 NRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSC-EPPRIRGAGTRELELAIRITLYAVIF
: : . :: ..: . :..: ::..::
NP_000 MDVVDSLLVNGSNITPPCELGLENETLFCLDQPR----PSKEWQPAVQILLYSLIF
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 LMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTV
:.:: :: :.:.:: ..:.::::: ::::::::::.: . ::::.:.:::. ::::..
NP_000 LLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLL
.::...:.::.::::::..::::.::::.:::.:::.:::::.::: .::.::: :: .
NP_000 VCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 MVPYPVYTVVQPVGPRVLQ----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLI
:.:::.:. . : : : :. ..:.: ..:::.::.:::.:: ::::::
NP_000 MTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLI
180 190 200 210 220 230
250 260 270 280 290
pF1KE0 SRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVG--EDSDGCYVQLPR
: ::: :..:.... .... : .: : . : :::::::.: :
NP_000 SLELYQGIKFEASQKKSAKER-----------------KPSTTSSGKYEDSDGCYLQKTR
240 250 260 270
300 310 320 330 340 350
pF1KE0 SRPALELTALTAPGPGSGSR----PTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTW
::: :.. . . ..: . :.:.:::::.:::.::::::::::.:..:::.:
NP_000 PPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAW
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE0 RAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRP--P
::.: .:.: :::.::::: ::::.:.::::..::::..::: . . : ::: : :
NP_000 RAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFP-CCPNPGPP
340 350 360 370 380 390
420 430 440
pF1KE0 RARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
:: .. .:. : . :::::.::. .:. :
NP_000 GARGEVGEEEEGGTTG-ASLSRFSYSHMSASVPPQ
400 410 420
>>XP_005263095 (OMIM: 602001) PREDICTED: neuropeptide Y (445 aa)
initn: 430 init1: 252 opt: 398 Z-score: 409.5 bits: 85.0 E(85289): 4.5e-16
Smith-Waterman score: 407; 25.6% identity (55.6% similar) in 410 aa overlap (58-408:45-442)
30 40 50 60 70 80
pF1KE0 LLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRT
: ::. . :.. ::.::...: .: .:
XP_005 TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 VTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVA
..: .. .:: ::.:... : :::: :. ..:: :.:. . .:. ::: :::: :..
XP_005 TVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILIS
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE0 IALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVY-TVVQ---PVGPRVL
::. :: : .:.. . : .:. .:...: :. . : ::. ..:. : .:
XP_005 IAIVRYHMIKHPISNNL--TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALL
140 150 160 170 180 190
210 220 230 240 250
pF1KE0 Q----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDS
. ::. ::: : .... :::. ...: : ..:.. . : . :: :..
XP_005 SSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGL-------SNK
200 210 220 230 240
260 270 280 290 300
pF1KE0 QSRVRNQGGLPGAVHQNGRCRPETGAVGEDS----------------DGCYVQLPRSRPA
..:.... . ..: . . :.. : . .: . :. ::.
XP_005 ENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPE-RPS
250 260 270 280 290 300
310 320 330
pF1KE0 LE----------------LTALTAPGPGSGS----RPTQA----KLLAKKRVVRM-----
: :.. . :: . .: . .: .:. :.:.
XP_005 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSR
310 320 330 340 350 360
340 350 360 370 380
pF1KE0 -----LLVIVVLFFLCWLPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPL
: .....: . :.:.. .. : :. ..: .. . . :::.. : :.::.
XP_005 SVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLV-YCICHLLGMMSCCLNPI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE0 VYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
.: :.. .. : : . .:
XP_005 LYGFLNNGIK-ADLVSLIHCLHM
430 440
>>NP_006165 (OMIM: 602001) neuropeptide Y receptor type (445 aa)
initn: 430 init1: 252 opt: 398 Z-score: 409.5 bits: 85.0 E(85289): 4.5e-16
Smith-Waterman score: 407; 25.6% identity (55.6% similar) in 410 aa overlap (58-408:45-442)
30 40 50 60 70 80
pF1KE0 LLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRT
: ::. . :.. ::.::...: .: .:
NP_006 TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 VTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVA
..: .. .:: ::.:... : :::: :. ..:: :.:. . .:. ::: :::: :..
NP_006 TVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILIS
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE0 IALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVY-TVVQ---PVGPRVL
::. :: : .:.. . : .:. .:...: :. . : ::. ..:. : .:
NP_006 IAIVRYHMIKHPISNNL--TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALL
140 150 160 170 180 190
210 220 230 240 250
pF1KE0 Q----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDS
. ::. ::: : .... :::. ...: : ..:.. . : . :: :..
NP_006 SSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGL-------SNK
200 210 220 230 240
260 270 280 290 300
pF1KE0 QSRVRNQGGLPGAVHQNGRCRPETGAVGEDS----------------DGCYVQLPRSRPA
..:.... . ..: . . :.. : . .: . :. ::.
NP_006 ENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPE-RPS
250 260 270 280 290 300
310 320 330
pF1KE0 LE----------------LTALTAPGPGSGS----RPTQA----KLLAKKRVVRM-----
: :.. . :: . .: . .: .:. :.:.
NP_006 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSR
310 320 330 340 350 360
340 350 360 370 380
pF1KE0 -----LLVIVVLFFLCWLPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPL
: .....: . :.:.. .. : :. ..: .. . . :::.. : :.::.
NP_006 SVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLV-YCICHLLGMMSCCLNPI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE0 VYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
.: :.. .. : : . .:
NP_006 LYGFLNNGIK-ADLVSLIHCLHM
430 440
>>NP_001304020 (OMIM: 602001) neuropeptide Y receptor ty (445 aa)
initn: 430 init1: 252 opt: 398 Z-score: 409.5 bits: 85.0 E(85289): 4.5e-16
Smith-Waterman score: 407; 25.6% identity (55.6% similar) in 410 aa overlap (58-408:45-442)
30 40 50 60 70 80
pF1KE0 LLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRT
: ::. . :.. ::.::...: .: .:
NP_001 TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 VTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVA
..: .. .:: ::.:... : :::: :. ..:: :.:. . .:. ::: :::: :..
NP_001 TVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILIS
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE0 IALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVY-TVVQ---PVGPRVL
::. :: : .:.. . : .:. .:...: :. . : ::. ..:. : .:
NP_001 IAIVRYHMIKHPISNNL--TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALL
140 150 160 170 180 190
210 220 230 240 250
pF1KE0 Q----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDS
. ::. ::: : .... :::. ...: : ..:.. . : . :: :..
NP_001 SSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGL-------SNK
200 210 220 230 240
260 270 280 290 300
pF1KE0 QSRVRNQGGLPGAVHQNGRCRPETGAVGEDS----------------DGCYVQLPRSRPA
..:.... . ..: . . :.. : . .: . :. ::.
NP_001 ENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPE-RPS
250 260 270 280 290 300
310 320 330
pF1KE0 LE----------------LTALTAPGPGSGS----RPTQA----KLLAKKRVVRM-----
: :.. . :: . .: . .: .:. :.:.
NP_001 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSR
310 320 330 340 350 360
340 350 360 370 380
pF1KE0 -----LLVIVVLFFLCWLPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPL
: .....: . :.:.. .. : :. ..: .. . . :::.. : :.::.
NP_001 SVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLV-YCICHLLGMMSCCLNPI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE0 VYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
.: :.. .. : : . .:
NP_001 LYGFLNNGIK-ADLVSLIHCLHM
430 440
>>XP_011530319 (OMIM: 602001) PREDICTED: neuropeptide Y (445 aa)
initn: 430 init1: 252 opt: 398 Z-score: 409.5 bits: 85.0 E(85289): 4.5e-16
Smith-Waterman score: 407; 25.6% identity (55.6% similar) in 410 aa overlap (58-408:45-442)
30 40 50 60 70 80
pF1KE0 LLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRT
: ::. . :.. ::.::...: .: .:
XP_011 TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 VTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVA
..: .. .:: ::.:... : :::: :. ..:: :.:. . .:. ::: :::: :..
XP_011 TVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILIS
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE0 IALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVY-TVVQ---PVGPRVL
::. :: : .:.. . : .:. .:...: :. . : ::. ..:. : .:
XP_011 IAIVRYHMIKHPISNNL--TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALL
140 150 160 170 180 190
210 220 230 240 250
pF1KE0 Q----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDS
. ::. ::: : .... :::. ...: : ..:.. . : . :: :..
XP_011 SSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGL-------SNK
200 210 220 230 240
260 270 280 290 300
pF1KE0 QSRVRNQGGLPGAVHQNGRCRPETGAVGEDS----------------DGCYVQLPRSRPA
..:.... . ..: . . :.. : . .: . :. ::.
XP_011 ENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPE-RPS
250 260 270 280 290 300
310 320 330
pF1KE0 LE----------------LTALTAPGPGSGS----RPTQA----KLLAKKRVVRM-----
: :.. . :: . .: . .: .:. :.:.
XP_011 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSR
310 320 330 340 350 360
340 350 360 370 380
pF1KE0 -----LLVIVVLFFLCWLPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPL
: .....: . :.:.. .. : :. ..: .. . . :::.. : :.::.
XP_011 SVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLV-YCICHLLGMMSCCLNPI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE0 VYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
.: :.. .. : : . .:
XP_011 LYGFLNNGIK-ADLVSLIHCLHM
430 440
>>NP_001304021 (OMIM: 602001) neuropeptide Y receptor ty (445 aa)
initn: 430 init1: 252 opt: 398 Z-score: 409.5 bits: 85.0 E(85289): 4.5e-16
Smith-Waterman score: 407; 25.6% identity (55.6% similar) in 410 aa overlap (58-408:45-442)
30 40 50 60 70 80
pF1KE0 LLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRT
: ::. . :.. ::.::...: .: .:
NP_001 TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 VTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVA
..: .. .:: ::.:... : :::: :. ..:: :.:. . .:. ::: :::: :..
NP_001 TVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILIS
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE0 IALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVY-TVVQ---PVGPRVL
::. :: : .:.. . : .:. .:...: :. . : ::. ..:. : .:
NP_001 IAIVRYHMIKHPISNNL--TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALL
140 150 160 170 180 190
210 220 230 240 250
pF1KE0 Q----CVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDS
. ::. ::: : .... :::. ...: : ..:.. . : . :: :..
NP_001 SSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGL-------SNK
200 210 220 230 240
260 270 280 290 300
pF1KE0 QSRVRNQGGLPGAVHQNGRCRPETGAVGEDS----------------DGCYVQLPRSRPA
..:.... . ..: . . :.. : . .: . :. ::.
NP_001 ENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPE-RPS
250 260 270 280 290 300
310 320 330
pF1KE0 LE----------------LTALTAPGPGSGS----RPTQA----KLLAKKRVVRM-----
: :.. . :: . .: . .: .:. :.:.
NP_001 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSR
310 320 330 340 350 360
340 350 360 370 380
pF1KE0 -----LLVIVVLFFLCWLPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPL
: .....: . :.:.. .. : :. ..: .. . . :::.. : :.::.
NP_001 SVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLV-YCICHLLGMMSCCLNPI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE0 VYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
.: :.. .. : : . .:
NP_001 LYGFLNNGIK-ADLVSLIHCLHM
430 440
447 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:17:37 2016 done: Sat Nov 5 18:17:38 2016
Total Scan time: 10.650 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]