FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0641, 217 aa 1>>>pF1KE0641 217 - 217 aa - 217 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0992+/-0.000333; mu= 9.3498+/- 0.022 mean_var=224.8120+/-50.790, 0's: 0 Z-trim(122.0): 61 B-trim: 6042 in 3/55 Lambda= 0.085539 statistics sampled from 39278 (39451) to 39278 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.463), width: 16 Scan time: 5.160 The best scores are: opt bits E(85289) NP_149105 (OMIM: 610750) zinc finger CCHC-type and ( 217) 1422 187.1 1.9e-47 XP_016875613 (OMIM: 610750) PREDICTED: zinc finger ( 176) 1166 155.4 5.5e-38 XP_005264542 (OMIM: 600572) PREDICTED: serine/argi ( 223) 220 38.8 0.0088 NP_001182375 (OMIM: 600572) serine/arginine-rich s ( 226) 220 38.8 0.0089 XP_005264541 (OMIM: 600572) PREDICTED: serine/argi ( 235) 220 38.8 0.0091 NP_001026854 (OMIM: 600572) serine/arginine-rich s ( 238) 220 38.8 0.0092 >>NP_149105 (OMIM: 610750) zinc finger CCHC-type and RNA (217 aa) initn: 1422 init1: 1422 opt: 1422 Z-score: 972.7 bits: 187.1 E(85289): 1.9e-47 Smith-Waterman score: 1422; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217) 10 20 30 40 50 60 pF1KE0 MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 KDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 PKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEE 130 140 150 160 170 180 190 200 210 pF1KE0 EQKKWKPSSGVPSTSDDSRRPRIKKSTYFSDEEELSD ::::::::::::::::::::::::::::::::::::: NP_149 EQKKWKPSSGVPSTSDDSRRPRIKKSTYFSDEEELSD 190 200 210 >>XP_016875613 (OMIM: 610750) PREDICTED: zinc finger CCH (176 aa) initn: 1166 init1: 1166 opt: 1166 Z-score: 803.0 bits: 155.4 E(85289): 5.5e-38 Smith-Waterman score: 1166; 100.0% identity (100.0% similar) in 176 aa overlap (42-217:1-176) 20 30 40 50 60 70 pF1KE0 VYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAI :::::::::::::::::::::::::::::: XP_016 MKDKDTRKSKGVAFILFLDKDSAQNCTRAI 10 20 30 80 90 100 110 120 130 pF1KE0 NNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPP 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 KKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGV 100 110 120 130 140 150 200 210 pF1KE0 PSTSDDSRRPRIKKSTYFSDEEELSD :::::::::::::::::::::::::: XP_016 PSTSDDSRRPRIKKSTYFSDEEELSD 160 170 >>XP_005264542 (OMIM: 600572) PREDICTED: serine/arginine (223 aa) initn: 161 init1: 108 opt: 220 Z-score: 170.9 bits: 38.8 E(85289): 0.0088 Smith-Waterman score: 220; 28.6% identity (60.0% similar) in 140 aa overlap (4-140:5-139) 10 20 30 40 50 pF1KE0 MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFL : ... :::.:: . ...: : :: :: . : : .:. : ::. : XP_005 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFE 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 DKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIR---RRNYFDKSKCYECGESGHL : .:.. .:....: . : ... .. : ..: : :: . ...::::::.:: XP_005 DPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQA .: : . .: ... ..... XP_005 AYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSAS 120 130 140 150 160 170 >>NP_001182375 (OMIM: 600572) serine/arginine-rich splic (226 aa) initn: 200 init1: 105 opt: 220 Z-score: 170.8 bits: 38.8 E(85289): 0.0089 Smith-Waterman score: 220; 28.6% identity (60.0% similar) in 140 aa overlap (4-140:5-139) 10 20 30 40 50 pF1KE0 MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFL : ... :::.:: . ...: : :: :: . : : .:. : ::. : NP_001 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFE 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 DKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIR---RRNYFDKSKCYECGESGHL : .:.. .:....: . : ... .. : ..: : :: . ...::::::.:: NP_001 DPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQA .: : . .: ... ..... NP_001 AYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSAS 120 130 140 150 160 170 >>XP_005264541 (OMIM: 600572) PREDICTED: serine/arginine (235 aa) initn: 161 init1: 108 opt: 220 Z-score: 170.7 bits: 38.8 E(85289): 0.0091 Smith-Waterman score: 220; 28.6% identity (60.0% similar) in 140 aa overlap (4-140:5-139) 10 20 30 40 50 pF1KE0 MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFL : ... :::.:: . ...: : :: :: . : : .:. : ::. : XP_005 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFE 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 DKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIR---RRNYFDKSKCYECGESGHL : .:.. .:....: . : ... .. : ..: : :: . ...::::::.:: XP_005 DPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQA .: : . .: ... ..... XP_005 AYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSAS 120 130 140 150 160 170 >>NP_001026854 (OMIM: 600572) serine/arginine-rich splic (238 aa) initn: 200 init1: 105 opt: 220 Z-score: 170.6 bits: 38.8 E(85289): 0.0092 Smith-Waterman score: 220; 28.6% identity (60.0% similar) in 140 aa overlap (4-140:5-139) 10 20 30 40 50 pF1KE0 MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFL : ... :::.:: . ...: : :: :: . : : .:. : ::. : NP_001 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFE 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 DKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIR---RRNYFDKSKCYECGESGHL : .:.. .:....: . : ... .. : ..: : :: . ...::::::.:: NP_001 DPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQA .: : . .: ... ..... NP_001 AYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSAS 120 130 140 150 160 170 217 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:14:24 2016 done: Wed Nov 2 19:14:24 2016 Total Scan time: 5.160 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]