Result of FASTA (omim) for
pF1KE0644
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0644, 431 aa
1>>>pF1KE0644 431 - 431 aa - 431 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0233+/-0.000539; mu= 18.9586+/- 0.034
mean_var=107.0694+/-27.765, 0's: 0 Z-trim(108.1): 639 B-trim: 1805 in 2/49
Lambda= 0.123949
statistics sampled from 15420 (16178) to 15420 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.529), E-opt: 0.2 (0.19), width: 16
Scan time: 6.820
The best scores are: opt bits E(85289)
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 2842 520.1 4.3e-147
XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamy ( 190) 1229 231.2 1.7e-60
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 649 127.9 4.7e-29
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 649 127.9 4.8e-29
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 649 128.1 5.4e-29
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 559 111.9 3.4e-24
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 556 111.3 4.6e-24
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 556 111.3 4.6e-24
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 556 111.3 4.6e-24
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 541 108.6 2.9e-23
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 541 108.6 2.9e-23
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 541 108.6 2.9e-23
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 541 108.6 2.9e-23
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 541 108.6 2.9e-23
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 541 108.6 2.9e-23
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 491 99.7 1.5e-20
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 487 98.9 2.4e-20
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 476 97.0 9.8e-20
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 475 96.9 1.1e-19
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 475 96.9 1.2e-19
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 474 96.6 1.2e-19
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 448 91.9 2.9e-18
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 447 91.8 3.4e-18
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 446 91.5 3.6e-18
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 447 91.8 3.6e-18
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 447 91.8 3.6e-18
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 447 91.8 3.6e-18
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 446 91.6 3.8e-18
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 446 91.6 3.8e-18
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 446 91.6 4e-18
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 439 90.4 9.2e-18
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 430 88.7 2.7e-17
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 430 88.7 2.7e-17
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 430 88.7 2.7e-17
XP_011529856 (OMIM: 607449) PREDICTED: neuropeptid ( 304) 428 88.2 3.1e-17
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 419 86.8 1.1e-16
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 402 83.8 9.7e-16
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 402 83.8 9.7e-16
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 402 83.9 1.1e-15
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 388 81.1 4.5e-15
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269) 385 80.5 5.8e-15
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 385 80.6 6.9e-15
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 386 80.9 6.9e-15
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 383 80.4 1e-14
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 369 77.7 4.4e-14
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 368 77.7 6.4e-14
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 364 77.0 1.1e-13
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 364 77.1 1.2e-13
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 360 76.2 1.6e-13
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 356 75.4 2.4e-13
>>NP_937822 (OMIM: 606925) pyroglutamylated RFamide pept (431 aa)
initn: 2842 init1: 2842 opt: 2842 Z-score: 2761.8 bits: 520.1 E(85289): 4.3e-147
Smith-Waterman score: 2842; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE0 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 VPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 WHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 WHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 LWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 FEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 FEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 RHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 RHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSE
370 380 390 400 410 420
430
pF1KE0 LAENSPLDSGH
:::::::::::
NP_937 LAENSPLDSGH
430
>>XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamylate (190 aa)
initn: 1229 init1: 1229 opt: 1229 Z-score: 1206.9 bits: 231.2 E(85289): 1.7e-60
Smith-Waterman score: 1229; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)
10 20 30 40 50 60
pF1KE0 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 WHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYE
:::::::
XP_016 WHVQQLEALP
190
>>NP_444264 (OMIM: 607449) neuropeptide FF receptor 2 is (420 aa)
initn: 588 init1: 334 opt: 649 Z-score: 642.5 bits: 127.9 E(85289): 4.7e-29
Smith-Waterman score: 649; 31.5% identity (65.6% similar) in 349 aa overlap (19-360:20-361)
10 20 30 40 50
pF1KE0 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALA
: :.... . . . : . : : . .... ::: :
NP_444 MNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAI-FIISYFLIFFLC
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICK
..::..: ..: :.: :.::::.:: .::.::::. .::.:.:.:.:: .: : .::
NP_444 MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 MVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSP
. .::. .:.. ..:.. :::.: : .:.::: : : . ::... ..:..:. . ::
NP_444 ISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFVIIMIIWVLAITIMSP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 ---MWHVQQLEIKYDFLYEKEHIC----CLEEWTSPVHQKIYTTFILVILFLLPLMVMLI
: :::. . : ... : :.: . .::::: ... ..: :: ...:
NP_444 SAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVV
.:..:: :. :.. . : . .. ..:::.. . :.. :. :: . : :. ..
NP_444 MYGRIGISLF---RAAVPHTGRK-NQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 HMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIV
:. .:... . .. .:. ... ..:.:: :::.:.:.::::... : .
NP_444 MMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLC
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE0 NKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKR
.: .: .
NP_444 QKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKE
360 370 380 390 400 410
>>NP_001138228 (OMIM: 607449) neuropeptide FF receptor 2 (423 aa)
initn: 588 init1: 334 opt: 649 Z-score: 642.5 bits: 127.9 E(85289): 4.8e-29
Smith-Waterman score: 649; 31.5% identity (65.6% similar) in 349 aa overlap (19-360:23-364)
10 20 30 40 50
pF1KE0 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIF
: :.... . . . : . : : . .... :::
NP_001 MFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAI-FIISYFLIF
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 ALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAF
: ..::..: ..: :.: :.::::.:: .::.::::. .::.:.:.:.:: .: :
NP_001 FLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIV
.::. .::. .:.. ..:.. :::.: : .:.::: : : . ::... ..:..:. .
NP_001 MCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFVIIMIIWVLAITI
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 GSP---MWHVQQLEIKYDFLYEKEHIC----CLEEWTSPVHQKIYTTFILVILFLLPLMV
:: : :::. . : ... : :.: . .::::: ... ..: :: .
NP_001 MSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 MLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPF
..:.:..:: :. :.. . : . .. ..:::.. . :.. :. :: . : :.
NP_001 IVIMYGRIGISLF---RAAVPHTGRK-NQEQWHVVSRKKQKIIKMLLIVALLFILSWLPL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE0 HVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCY
.. :. .:... . .. .:. ... ..:.:: :::.:.:.::::... :
NP_001 WTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE0 CIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKK
. .: .: .
NP_001 QLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEE
360 370 380 390 400 410
>>NP_004876 (OMIM: 607449) neuropeptide FF receptor 2 is (522 aa)
initn: 588 init1: 334 opt: 649 Z-score: 641.5 bits: 128.1 E(85289): 5.4e-29
Smith-Waterman score: 649; 31.5% identity (65.6% similar) in 349 aa overlap (19-360:122-463)
10 20 30 40
pF1KE0 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLAL
: :.... . . . : . : : . .
NP_004 AADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAI-F
100 110 120 130 140 150
50 60 70 80 90 100
pF1KE0 VLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNIS
... ::: : ..::..: ..: :.: :.::::.:: .::.::::. .::.:.:.:.::
NP_004 IISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNII
160 170 180 190 200 210
110 120 130 140 150 160
pF1KE0 DNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGV
.: : .::. .::. .:.. ..:.. :::.: : .:.::: : : . ::... .
NP_004 AGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFVIIMI
220 230 240 250 260
170 180 190 200 210 220
pF1KE0 VWLVAVIVGSP---MWHVQQLEIKYDFLYEKEHIC----CLEEWTSPVHQKIYTTFILVI
.:..:. . :: : :::. . : ... : :.: . .::::: ...
NP_004 IWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFAN
270 280 290 300 310 320
230 240 250 260 270 280
pF1KE0 LFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVAL
..: :: ...:.:..:: :. :.. . : . .. ..:::.. . :.. :. :
NP_004 IYLAPLSLIVIMYGRIGISLF---RAAVPHTGRK-NQEQWHVVSRKKQKIIKMLLIVALL
330 340 350 360 370 380
290 300 310 320 330 340
pF1KE0 FAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKK
: . : :. .. :. .:... . .. .:. ... ..:.:: :::.:.:.::::..
NP_004 FILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR
390 400 410 420 430 440
350 360 370 380 390 400
pF1KE0 NVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLC
. : . .: .: .
NP_004 GFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKP
450 460 470 480 490 500
>>NP_071429 (OMIM: 607448) neuropeptide FF receptor 1 [H (430 aa)
initn: 455 init1: 308 opt: 559 Z-score: 555.4 bits: 111.9 E(85289): 3.4e-24
Smith-Waterman score: 559; 30.0% identity (65.1% similar) in 307 aa overlap (48-346:46-343)
20 30 40 50 60 70
pF1KE0 HNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMR
.... .::: : . ::.:: ..: ... :.
NP_071 SQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMH
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE0 TVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMT
::::.:: .::.::::. .::.:.:...:. .: ::: .::. .: . ..:..
NP_071 TVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLV
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 CIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSP-MWHVQQLEIKYDFLYEK
::::: . .::::. : : :.:.. ..:.: .:... : . . .. :. .
NP_071 AIAVERFRCIVHPFREK--LTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHFMVDA
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 EH-----ICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGS
.. : : : ...::: .. ..: :: .....:..:. .: . :
NP_071 RNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPG-
200 210 220 230 240 250
260 270 280 290 300
pF1KE0 VLRTIHGKEMS--KIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVT
:.: . . .:.. :.: :.: :. .:.. : :. .. ..:.:... ..
NP_071 ------GEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLV
260 270 280 290 300
310 320 330 340 350 360
pF1KE0 IKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITM
. : ... ..: :: :::.:...::::... .:
NP_071 TVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 MRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDS
NP_071 LLHRRVFVVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVAHHGLPREGPGCSHLPLTIP
370 380 390 400 410 420
>>XP_005263088 (OMIM: 162641) PREDICTED: neuropeptide Y (384 aa)
initn: 483 init1: 290 opt: 556 Z-score: 553.1 bits: 111.3 E(85289): 4.6e-24
Smith-Waterman score: 558; 29.1% identity (65.7% similar) in 347 aa overlap (46-387:43-374)
20 30 40 50 60 70
pF1KE0 RDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKA
:::. .:.: :.. :: .. .. ..:
XP_005 SVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVII--LGVSGNLALIIIILKQKE
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE0 MRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILT
::.::::.: .:..::::....:.: :.. .. :.:. : .::. :::: ..... :..
XP_005 MRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFS
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 MTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSP--MWHVQQLEIKYDFL
.. ::::::: ...: :. .::.:.. ..:.:..:: . : ...:. : .
XP_005 LVLIAVERHQLIINP--RGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVT
140 150 160 170 180
200 210 220 230 240 250
pF1KE0 YE--KEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGS
. :.. :.... : :. :::..::. .. :: ..: : :: .: :.: ..
XP_005 LDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRL--KRR---NN
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE0 VLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIK
.. .. ... . . :: ::....:. ::::: :. . . ...... . . .
XP_005 MMDKMRDNKYR--SSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNH--QIIATCNHN
250 260 270 280 290
320 330 340 350 360 370
pF1KE0 MIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMR
..: . .. .. .. ::: :.:.:.::.... .: . . . . : ::
XP_005 LLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMS--TMHT
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE0 KKAKFSLRE-NPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSG
.: ::.. .:: :
XP_005 DVSKTSLKQASPVAFKKINNNDDNEKI
360 370 380
>>NP_000900 (OMIM: 162641) neuropeptide Y receptor type (384 aa)
initn: 483 init1: 290 opt: 556 Z-score: 553.1 bits: 111.3 E(85289): 4.6e-24
Smith-Waterman score: 558; 29.1% identity (65.7% similar) in 347 aa overlap (46-387:43-374)
20 30 40 50 60 70
pF1KE0 RDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKA
:::. .:.: :.. :: .. .. ..:
NP_000 SVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVII--LGVSGNLALIIIILKQKE
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE0 MRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILT
::.::::.: .:..::::....:.: :.. .. :.:. : .::. :::: ..... :..
NP_000 MRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFS
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 MTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSP--MWHVQQLEIKYDFL
.. ::::::: ...: :. .::.:.. ..:.:..:: . : ...:. : .
NP_000 LVLIAVERHQLIINP--RGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVT
140 150 160 170 180
200 210 220 230 240 250
pF1KE0 YE--KEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGS
. :.. :.... : :. :::..::. .. :: ..: : :: .: :.: ..
NP_000 LDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRL--KRR---NN
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE0 VLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIK
.. .. ... . . :: ::....:. ::::: :. . . ...... . . .
NP_000 MMDKMRDNKYR--SSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNH--QIIATCNHN
250 260 270 280 290
320 330 340 350 360 370
pF1KE0 MIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMR
..: . .. .. .. ::: :.:.:.::.... .: . . . . : ::
NP_000 LLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMS--TMHT
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE0 KKAKFSLRE-NPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSG
.: ::.. .:: :
NP_000 DVSKTSLKQASPVAFKKINNNDDNEKI
360 370 380
>>XP_011530312 (OMIM: 162641) PREDICTED: neuropeptide Y (384 aa)
initn: 483 init1: 290 opt: 556 Z-score: 553.1 bits: 111.3 E(85289): 4.6e-24
Smith-Waterman score: 558; 29.1% identity (65.7% similar) in 347 aa overlap (46-387:43-374)
20 30 40 50 60 70
pF1KE0 RDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKA
:::. .:.: :.. :: .. .. ..:
XP_011 SVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVII--LGVSGNLALIIIILKQKE
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE0 MRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILT
::.::::.: .:..::::....:.: :.. .. :.:. : .::. :::: ..... :..
XP_011 MRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFS
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 MTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSP--MWHVQQLEIKYDFL
.. ::::::: ...: :. .::.:.. ..:.:..:: . : ...:. : .
XP_011 LVLIAVERHQLIINP--RGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVT
140 150 160 170 180
200 210 220 230 240 250
pF1KE0 YE--KEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGS
. :.. :.... : :. :::..::. .. :: ..: : :: .: :.: ..
XP_011 LDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRL--KRR---NN
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE0 VLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIK
.. .. ... . . :: ::....:. ::::: :. . . ...... . . .
XP_011 MMDKMRDNKYR--SSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNH--QIIATCNHN
250 260 270 280 290
320 330 340 350 360 370
pF1KE0 MIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMR
..: . .. .. .. ::: :.:.:.::.... .: . . . . : ::
XP_011 LLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMS--TMHT
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE0 KKAKFSLRE-NPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSG
.: ::.. .:: :
XP_011 DVSKTSLKQASPVAFKKINNNDDNEKI
360 370 380
>>NP_001265723 (OMIM: 601790) neuropeptide Y receptor ty (375 aa)
initn: 462 init1: 245 opt: 541 Z-score: 538.7 bits: 108.6 E(85289): 2.9e-23
Smith-Waterman score: 542; 28.4% identity (62.5% similar) in 352 aa overlap (46-383:41-375)
20 30 40 50 60 70
pF1KE0 RDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLI-FALALFGNALVFYVVTRSK
.....:. : .....:: .. :..:.:
NP_001 LPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQK
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE0 AMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEIL
.:::..: .::.::.:. ..: :.: . .: : :. : .::: :.: .:.. ::
NP_001 EKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSIL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 TMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKY----
... .:.:::: ...: :. . .:. . ..:..: ... :. . :: .
NP_001 SLVLVALERHQLIINP--TGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNH
140 150 160 170 180
200 210 220 230 240
pF1KE0 ----DFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKR
.:: .: . : : : :. :::::.:.. . ::: .:. :..: : .:
NP_001 SKALEFLADK--VVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRCL---QR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 VGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYD
: :..: .: : . :.. ...:..:. ::: : :.:: . . .. ...
NP_001 QG-----RVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDW-----HHE
250 260 270 280 290
310 320 330 340 350 360
pF1KE0 DVTI---KMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHG
. : ..:: . ........ ::..:.:.: ::::.. . : : . . ...
NP_001 AIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 NSGITMMRKKAKFSL--RENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSEL
: . .:... : : ::.
NP_001 LSTVHTEVSKGSLRLSGRSNPI
360 370
431 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:42:07 2016 done: Sat Nov 5 18:42:08 2016
Total Scan time: 6.820 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]