Result of FASTA (omim) for
pF1KE0646
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0646, 380 aa
1>>>pF1KE0646 380 - 380 aa - 380 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6866+/-0.000326; mu= 6.5238+/- 0.020
mean_var=150.2464+/-31.379, 0's: 0 Z-trim(120.4): 51 B-trim: 2842 in 2/53
Lambda= 0.104634
statistics sampled from 35601 (35667) to 35601 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.418), width: 16
Scan time: 6.630
The best scores are: opt bits E(85289)
NP_061863 (OMIM: 300441) SAM and SH3 domain-contai ( 380) 2517 391.3 2e-108
XP_006724826 (OMIM: 300441) PREDICTED: SAM and SH3 ( 430) 1320 210.6 5.4e-54
NP_001333436 (OMIM: 607955) SAM and SH3 domain-con (1008) 834 137.5 1.3e-31
NP_001333435 (OMIM: 607955) SAM and SH3 domain-con (1123) 834 137.6 1.4e-31
NP_001333434 (OMIM: 607955) SAM and SH3 domain-con (1202) 834 137.6 1.5e-31
NP_056093 (OMIM: 607955) SAM and SH3 domain-contai (1247) 834 137.6 1.5e-31
NP_071419 (OMIM: 607978) SAM domain-containing pro ( 373) 821 135.3 2.3e-31
NP_001333438 (OMIM: 607955) SAM and SH3 domain-con (1130) 829 136.8 2.4e-31
NP_001333437 (OMIM: 607955) SAM and SH3 domain-con (1171) 829 136.8 2.5e-31
XP_016866094 (OMIM: 607955) PREDICTED: SAM and SH3 (1286) 829 136.8 2.7e-31
XP_016866093 (OMIM: 607955) PREDICTED: SAM and SH3 (1291) 829 136.8 2.7e-31
XP_016866092 (OMIM: 607955) PREDICTED: SAM and SH3 (1317) 829 136.8 2.7e-31
XP_016866091 (OMIM: 607955) PREDICTED: SAM and SH3 (1317) 829 136.8 2.7e-31
XP_016866090 (OMIM: 607955) PREDICTED: SAM and SH3 (1351) 829 136.9 2.8e-31
XP_016866089 (OMIM: 607955) PREDICTED: SAM and SH3 (1365) 829 136.9 2.8e-31
XP_016866088 (OMIM: 607955) PREDICTED: SAM and SH3 (1373) 829 136.9 2.8e-31
XP_016866087 (OMIM: 607955) PREDICTED: SAM and SH3 (1410) 829 136.9 2.9e-31
XP_011527986 (OMIM: 607978) PREDICTED: SAM domain- ( 355) 816 134.5 3.7e-31
NP_001243299 (OMIM: 607978) SAM domain-containing ( 441) 816 134.6 4.4e-31
XP_011527988 (OMIM: 607978) PREDICTED: SAM domain- ( 309) 766 126.9 6.2e-29
XP_016883916 (OMIM: 607978) PREDICTED: SAM domain- ( 311) 761 126.2 1.1e-28
NP_001273452 (OMIM: 607978) SAM domain-containing ( 304) 755 125.3 1.9e-28
XP_011527987 (OMIM: 607978) PREDICTED: SAM domain- ( 323) 693 115.9 1.3e-25
>>NP_061863 (OMIM: 300441) SAM and SH3 domain-containing (380 aa)
initn: 2517 init1: 2517 opt: 2517 Z-score: 2067.7 bits: 391.3 E(85289): 2e-108
Smith-Waterman score: 2517; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 RPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD
310 320 330 340 350 360
370 380
pF1KE0 DAELAGTEEQLQGLSLAGAP
::::::::::::::::::::
NP_061 DAELAGTEEQLQGLSLAGAP
370 380
>>XP_006724826 (OMIM: 300441) PREDICTED: SAM and SH3 dom (430 aa)
initn: 1320 init1: 1320 opt: 1320 Z-score: 1090.3 bits: 210.6 E(85289): 5.4e-54
Smith-Waterman score: 2296; 87.9% identity (87.9% similar) in 412 aa overlap (1-362:1-412)
10 20 30 40 50 60
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV
130 140 150 160 170 180
190
pF1KE0 HTDFTPSPYDHDSLKLQ-------------------------------------------
:::::::::::::::::
XP_006 HTDFTPSPYDHDSLKLQVRSASGLLWSLAGCAQKGSWTEPGYDSVSGGQGPPYPLSLAPF
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE0 -------KGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPLPQQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGK
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE0 RPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAA
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE0 ELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQ
370 380 390 400 410 420
380
pF1KE0 LQGLSLAGAP
XP_006 LQGLSLAGAP
430
>>NP_001333436 (OMIM: 607955) SAM and SH3 domain-contain (1008 aa)
initn: 830 init1: 694 opt: 834 Z-score: 688.5 bits: 137.5 E(85289): 1.3e-31
Smith-Waterman score: 834; 45.6% identity (67.0% similar) in 351 aa overlap (20-357:161-494)
10 20 30 40
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLD
:: :. :: : .. : : :. : :
NP_001 GTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSN---NSD
140 150 160 170 180
50 60 70 80 90 100
pF1KE0 DNIPEDD----SGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA--DT
: : . .: : .:::: ..: ..:: ..:.: . ...::. . :
NP_001 PMGKEGDFVYKEVIKSPT---ASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDSGLDG
190 200 210 220 230 240
110 120 130 140 150
pF1KE0 LEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELCSPSP
. :: :..:: ::.: : :.. ..: : ..: :. :. : .
NP_001 MP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKS
250 260 270 280 290 300
160 170 180 190 200 210
pF1KE0 GSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGL
.:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.:::.::
NP_001 EDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGL
310 320 330 340 350
220 230 240 250 260 270
pF1KE0 LNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLN
::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :.:.:
NP_001 LNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFN
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE0 GYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAH
::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .::: .
NP_001 GYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQEKLLV
420 430 440 450 460 470
340 350 360 370 380
pF1KE0 TVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . ::::::.:.::.
NP_001 DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLM
480 490 500 510 520 530
>>NP_001333435 (OMIM: 607955) SAM and SH3 domain-contain (1123 aa)
initn: 830 init1: 694 opt: 834 Z-score: 687.8 bits: 137.6 E(85289): 1.4e-31
Smith-Waterman score: 834; 45.6% identity (67.0% similar) in 351 aa overlap (20-357:276-609)
10 20 30 40
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLD
:: :. :: : .. : : :. : :
NP_001 GTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSN---NSD
250 260 270 280 290 300
50 60 70 80 90 100
pF1KE0 DNIPEDD----SGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA--DT
: : . .: : .:::: ..: ..:: ..:.: . ...::. . :
NP_001 PMGKEGDFVYKEVIKSPT---ASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDSGLDG
310 320 330 340 350
110 120 130 140 150
pF1KE0 LEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELCSPSP
. :: :..:: ::.: : :.. ..: : ..: :. :. : .
NP_001 MP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKS
360 370 380 390 400 410
160 170 180 190 200 210
pF1KE0 GSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGL
.:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.:::.::
NP_001 EDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGL
420 430 440 450 460 470
220 230 240 250 260 270
pF1KE0 LNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLN
::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :.:.:
NP_001 LNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFN
480 490 500 510 520 530
280 290 300 310 320 330
pF1KE0 GYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAH
::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .::: .
NP_001 GYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQEKLLV
540 550 560 570 580
340 350 360 370 380
pF1KE0 TVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . ::::::.:.::.
NP_001 DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLM
590 600 610 620 630 640
>>NP_001333434 (OMIM: 607955) SAM and SH3 domain-contain (1202 aa)
initn: 830 init1: 694 opt: 834 Z-score: 687.4 bits: 137.6 E(85289): 1.5e-31
Smith-Waterman score: 834; 45.6% identity (67.0% similar) in 351 aa overlap (20-357:355-688)
10 20 30 40
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLD
:: :. :: : .. : : :. : :
NP_001 GTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSN---NSD
330 340 350 360 370 380
50 60 70 80 90 100
pF1KE0 DNIPEDD----SGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA--DT
: : . .: : .:::: ..: ..:: ..:.: . ...::. . :
NP_001 PMGKEGDFVYKEVIKSPT---ASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDSGLDG
390 400 410 420 430
110 120 130 140 150
pF1KE0 LEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELCSPSP
. :: :..:: ::.: : :.. ..: : ..: :. :. : .
NP_001 MP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKS
440 450 460 470 480 490
160 170 180 190 200 210
pF1KE0 GSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGL
.:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.:::.::
NP_001 EDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGL
500 510 520 530 540 550
220 230 240 250 260 270
pF1KE0 LNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLN
::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :.:.:
NP_001 LNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFN
560 570 580 590 600 610
280 290 300 310 320 330
pF1KE0 GYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAH
::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .::: .
NP_001 GYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQEKLLV
620 630 640 650 660
340 350 360 370 380
pF1KE0 TVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . ::::::.:.::.
NP_001 DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLM
670 680 690 700 710 720
>>NP_056093 (OMIM: 607955) SAM and SH3 domain-containing (1247 aa)
initn: 830 init1: 694 opt: 834 Z-score: 687.2 bits: 137.6 E(85289): 1.5e-31
Smith-Waterman score: 834; 45.6% identity (67.0% similar) in 351 aa overlap (20-357:400-733)
10 20 30 40
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLD
:: :. :: : .. : : :. : :
NP_056 GTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSN---NSD
370 380 390 400 410 420
50 60 70 80 90 100
pF1KE0 DNIPEDD----SGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA--DT
: : . .: : .:::: ..: ..:: ..:.: . ...::. . :
NP_056 PMGKEGDFVYKEVIKSPT---ASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDSGLDG
430 440 450 460 470 480
110 120 130 140 150
pF1KE0 LEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELCSPSP
. :: :..:: ::.: : :.. ..: : ..: :. :. : .
NP_056 MP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKS
490 500 510 520 530 540
160 170 180 190 200 210
pF1KE0 GSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGL
.:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.:::.::
NP_056 EDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGL
550 560 570 580 590
220 230 240 250 260 270
pF1KE0 LNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLN
::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :.:.:
NP_056 LNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFN
600 610 620 630 640 650
280 290 300 310 320 330
pF1KE0 GYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAH
::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .::: .
NP_056 GYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQEKLLV
660 670 680 690 700 710
340 350 360 370 380
pF1KE0 TVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . ::::::.:.::.
NP_056 DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLM
720 730 740 750 760 770
>>NP_071419 (OMIM: 607978) SAM domain-containing protein (373 aa)
initn: 812 init1: 368 opt: 821 Z-score: 684.1 bits: 135.3 E(85289): 2.3e-31
Smith-Waterman score: 886; 45.7% identity (68.7% similar) in 374 aa overlap (1-363:1-355)
10 20 30 40 50 60
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
::.:::::.:::: :: : ::::: .: . . .: . . .. : . ::
NP_071 MLKRKPSNVSEKEKHQKPK----RSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQ
10 20 30 40 50
70 80 90 100 110
pF1KE0 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEG-SASPTSPDYSLD
. ....: :::: :: :: ::..:.:: ..:::::: . :.: .: : . .
NP_071 SK--TSNNGGGLGKKMRA-ISWTMKKKVGKKYIKALSEEKDE--EDGENAHPYRNSDPVI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGS-GSFGEEPPAPQYTGPFCGRA
. ::..: :.. . ....:.: :: . .. :: . .: :.:::::::
NP_071 GTHTEKVSLKASDSMDSLYS--GQSSSSGITSCSDGTSNRDSFRLDDDGP-YSGPFCGRA
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 RVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVG
:::::::::::: ::::..:::.:.:: : :.: : :.::.:::.::::::::. :: ..
NP_071 RVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 HAR-PSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNI
. . :.:..: : :::.:.:::: :.:.:::::::::.::::.:...:.:: ::::
NP_071 PKKIKANRRSNSK--KSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNI
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 MDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHT--VSEPKV---DIPRDSGCF
.:. : .::.::: .:. :: . :. ::.. . .: : : ::::::.
NP_071 ENPDDRRRLLSAAENFLE-----EEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCY
290 300 310 320 330 340
360 370 380
pF1KE0 --EG-SESGRDDAELAGTEEQLQGLSLAGAP
: :..:..: :
NP_071 ISSGNSDNGKEDLESENLSDMVHKIIITEPSD
350 360 370
>>NP_001333438 (OMIM: 607955) SAM and SH3 domain-contain (1130 aa)
initn: 798 init1: 694 opt: 829 Z-score: 683.7 bits: 136.8 E(85289): 2.4e-31
Smith-Waterman score: 829; 49.2% identity (72.2% similar) in 295 aa overlap (72-357:333-616)
50 60 70 80 90 100
pF1KE0 SEKEFNLDDNIPEDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA
:::: ..: ..:: ..:.: . ...::. .
NP_001 VGSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDS
310 320 330 340 350 360
110 120 130 140 150
pF1KE0 --DTLEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELC
: . :: :..:: ::.: : :.. ..: : ..: :. :.
NP_001 GLDGMP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRE
370 380 390 400 410 420
160 170 180 190 200 210
pF1KE0 SPSPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGT
: . .:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.::
NP_001 SVKSEDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGT
430 440 450 460 470
220 230 240 250 260 270
pF1KE0 WLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTST
:.::::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :
NP_001 WMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPT
480 490 500 510 520 530
280 290 300 310 320 330
pF1KE0 LLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQE
.:.:::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .:::
NP_001 FLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQE
540 550 560 570 580 590
340 350 360 370 380
pF1KE0 PVAHTVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . . ::::::.:.::.
NP_001 KLLVDSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPT
600 610 620 630 640 650
>>NP_001333437 (OMIM: 607955) SAM and SH3 domain-contain (1171 aa)
initn: 798 init1: 694 opt: 829 Z-score: 683.5 bits: 136.8 E(85289): 2.5e-31
Smith-Waterman score: 829; 49.2% identity (72.2% similar) in 295 aa overlap (72-357:374-657)
50 60 70 80 90 100
pF1KE0 SEKEFNLDDNIPEDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA
:::: ..: ..:: ..:.: . ...::. .
NP_001 VGSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDS
350 360 370 380 390 400
110 120 130 140 150
pF1KE0 --DTLEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELC
: . :: :..:: ::.: : :.. ..: : ..: :. :.
NP_001 GLDGMP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRE
410 420 430 440 450 460
160 170 180 190 200 210
pF1KE0 SPSPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGT
: . .:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.::
NP_001 SVKSEDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGT
470 480 490 500 510
220 230 240 250 260 270
pF1KE0 WLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTST
:.::::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :
NP_001 WMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPT
520 530 540 550 560 570
280 290 300 310 320 330
pF1KE0 LLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQE
.:.:::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .:::
NP_001 FLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQE
580 590 600 610 620 630
340 350 360 370 380
pF1KE0 PVAHTVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . . ::::::.:.::.
NP_001 KLLVDSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPT
640 650 660 670 680 690
>>XP_016866094 (OMIM: 607955) PREDICTED: SAM and SH3 dom (1286 aa)
initn: 798 init1: 694 opt: 829 Z-score: 682.9 bits: 136.8 E(85289): 2.7e-31
Smith-Waterman score: 829; 49.2% identity (72.2% similar) in 295 aa overlap (72-357:489-772)
50 60 70 80 90 100
pF1KE0 SEKEFNLDDNIPEDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA
:::: ..: ..:: ..:.: . ...::. .
XP_016 VGSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDS
460 470 480 490 500 510
110 120 130 140 150
pF1KE0 --DTLEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELC
: . :: :..:: ::.: : :.. ..: : ..: :. :.
XP_016 GLDGMP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRE
520 530 540 550 560 570
160 170 180 190 200 210
pF1KE0 SPSPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGT
: . .:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.::
XP_016 SVKSEDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGT
580 590 600 610 620 630
220 230 240 250 260 270
pF1KE0 WLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTST
:.::::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :
XP_016 WMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPT
640 650 660 670 680 690
280 290 300 310 320 330
pF1KE0 LLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQE
.:.:::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .:::
XP_016 FLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQE
700 710 720 730 740
340 350 360 370 380
pF1KE0 PVAHTVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . . ::::::.:.::.
XP_016 KLLVDSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPT
750 760 770 780 790 800
380 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:09:30 2016 done: Wed Nov 2 19:09:31 2016
Total Scan time: 6.630 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]