FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0653, 221 aa 1>>>pF1KE0653 221 - 221 aa - 221 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5286+/-0.000686; mu= 14.3417+/- 0.041 mean_var=104.5912+/-22.124, 0's: 0 Z-trim(112.6): 116 B-trim: 0 in 0/50 Lambda= 0.125408 statistics sampled from 13199 (13340) to 13199 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.41), width: 16 Scan time: 1.900 The best scores are: opt bits E(32554) CCDS9199.1 SRSF9 gene_id:8683|Hs108|chr12 ( 221) 1568 293.4 7.6e-80 CCDS11600.1 SRSF1 gene_id:6426|Hs108|chr17 ( 248) 977 186.5 1.3e-47 CCDS58580.1 SRSF1 gene_id:6426|Hs108|chr17 ( 201) 865 166.2 1.4e-41 CCDS333.1 SRSF4 gene_id:6429|Hs108|chr1 ( 494) 414 85.0 9.4e-17 CCDS32109.1 SRSF5 gene_id:6430|Hs108|chr14 ( 272) 335 70.4 1.3e-12 >>CCDS9199.1 SRSF9 gene_id:8683|Hs108|chr12 (221 aa) initn: 1568 init1: 1568 opt: 1568 Z-score: 1546.9 bits: 293.4 E(32554): 7.6e-80 Smith-Waterman score: 1568; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221) 10 20 30 40 50 60 pF1KE0 MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 DPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 SGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYI 130 140 150 160 170 180 190 200 210 220 pF1KE0 RVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY ::::::::::::::::::::::::::::::::::::::::: CCDS91 RVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY 190 200 210 220 >>CCDS11600.1 SRSF1 gene_id:6426|Hs108|chr17 (248 aa) initn: 1081 init1: 549 opt: 977 Z-score: 968.4 bits: 186.5 E(32554): 1.3e-47 Smith-Waterman score: 1004; 66.8% identity (78.8% similar) in 241 aa overlap (1-217:1-239) 10 20 30 40 50 pF1KE0 MSGWADERG--GEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVR ::: . :: :..: :::::::: :.: ::.::.::::: ::.:.::::.: :::::. CCDS11 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 FEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTY---------GGRGGWPRGGRNGPPTRRS ::::::::::.:::.:::: ::::::::. :: :: ::: : :::.::: CCDS11 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRG-RYGPPSRRS 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 DFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTK . ::.:::::::::::::::::::::::::::: .::.:.::..::::: ::.::::.:: CCDS11 ENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTK 120 130 140 150 160 170 170 180 190 200 210 pF1KE0 FRSHEGETSYIRVYPE--RSTSYGYSRSRSGSRGRD-----------SPYQSRGSPHYFS ::::::::.:::: . :: ::: ::::: ::.:. :: .:::::.: : CCDS11 FRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRY-S 180 190 200 210 220 230 220 pF1KE0 PFRPY : CCDS11 PRHSRSRSRT 240 >>CCDS58580.1 SRSF1 gene_id:6426|Hs108|chr17 (201 aa) initn: 507 init1: 462 opt: 865 Z-score: 860.1 bits: 166.2 E(32554): 1.4e-41 Smith-Waterman score: 875; 68.9% identity (82.4% similar) in 193 aa overlap (1-182:1-190) 10 20 30 40 50 pF1KE0 MSGWADERG--GEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVR ::: . :: :..: :::::::: :.: ::.::.::::: ::.:.::::.: :::::. CCDS58 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 FEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTY---------GGRGGWPRGGRNGPPTRRS ::::::::::.:::.:::: ::::::::. :: :: ::: : :::.::: CCDS58 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRG-RYGPPSRRS 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 DFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTK . ::.:::::::::::::::::::::::::::: .::.:.::..::::: ::.::::.:: CCDS58 ENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 FRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY ::::: ..: :. CCDS58 FRSHE--VGYTRILFFDQNWIQWS 180 190 200 >>CCDS333.1 SRSF4 gene_id:6429|Hs108|chr1 (494 aa) initn: 283 init1: 125 opt: 414 Z-score: 414.2 bits: 85.0 E(32554): 9.4e-17 Smith-Waterman score: 476; 42.9% identity (66.2% similar) in 210 aa overlap (15-211:3-204) 10 20 30 40 50 60 pF1KE0 MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFE :.:.: : ..::.:.: .: ::.: :..::: .: ::.:. CCDS33 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG-----FVEFD 10 20 30 40 70 80 90 100 pF1KE0 DPRDAEDAIYGRNGYDYGQCRLRVEF---PR---TYG-GRGGWP--RGGRN--GPPTRRS : :::.::.: :: : :. :: :: .:: ::.:. :.::. ::::: . CCDS33 DLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTR-T 50 60 70 80 90 100 110 120 130 140 150 160 pF1KE0 DFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKD--GVGMVEYLRKEDMEYALRKLDD ..:..: .: :::::::.::.::.: :::..: . :..:.. ::. ::.::: CCDS33 EYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDG 110 120 130 140 150 160 170 180 190 200 210 220 pF1KE0 TKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY :. ... .. : .:::::: ::.:. .:: : CCDS33 TEVNGRK--IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRS 170 180 190 200 210 220 CCDS33 RSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 230 240 250 260 270 280 >>CCDS32109.1 SRSF5 gene_id:6430|Hs108|chr14 (272 aa) initn: 446 init1: 155 opt: 335 Z-score: 340.2 bits: 70.4 E(32554): 1.3e-12 Smith-Waterman score: 427; 39.6% identity (61.8% similar) in 217 aa overlap (15-209:5-216) 10 20 30 40 50 60 pF1KE0 MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFE :...: : .::::.: .: :::::.:.:: .: :.::.:: CCDS32 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG---FGFVEFE 10 20 30 40 70 80 90 100 pF1KE0 DPRDAEDAIYGRNGYDYGQCRLRVEFPR--TYGGRG-GW---------PRGGRNGPPTRR :::::.::.: .: . . :. .: : . :::: : ::. : . : : CCDS32 DPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVR 50 60 70 80 90 100 110 120 130 140 150 160 pF1KE0 SDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGV--GMVEYLRKEDMEYALRKL- .. :..: .: ::::::: ::.::.: .::... . :.::. :.. :..:: CCDS32 TENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLS 110 120 130 140 150 160 170 180 190 200 210 pF1KE0 ----DDTKFRSHEGETSYIRVYPE---RSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPF . :.. :: . : . :. : . ::::: ::.: : .:: CCDS32 GKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRS 170 180 190 200 210 220 220 pF1KE0 RPY CCDS32 KSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 230 240 250 260 270 221 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:50:58 2016 done: Wed Nov 2 18:50:59 2016 Total Scan time: 1.900 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]