FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0654, 386 aa 1>>>pF1KE0654 386 - 386 aa - 386 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3105+/-0.00112; mu= 13.1476+/- 0.067 mean_var=151.0317+/-31.836, 0's: 0 Z-trim(108.1): 174 B-trim: 471 in 1/51 Lambda= 0.104361 statistics sampled from 9796 (10010) to 9796 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.307), width: 16 Scan time: 1.810 The best scores are: opt bits E(32554) CCDS1901.1 TIA1 gene_id:7072|Hs108|chr2 ( 386) 2691 417.2 1.2e-116 CCDS1900.1 TIA1 gene_id:7072|Hs108|chr2 ( 375) 2010 314.7 8.7e-86 CCDS31295.1 TIAL1 gene_id:7073|Hs108|chr10 ( 392) 1697 267.6 1.4e-71 CCDS7613.1 TIAL1 gene_id:7073|Hs108|chr10 ( 375) 1516 240.3 2.1e-63 CCDS9311.1 PABPC3 gene_id:5042|Hs108|chr13 ( 631) 413 74.5 3e-13 >>CCDS1901.1 TIA1 gene_id:7072|Hs108|chr2 (386 aa) initn: 2691 init1: 2691 opt: 2691 Z-score: 2207.6 bits: 417.2 E(32554): 1.2e-116 Smith-Waterman score: 2691; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386) 10 20 30 40 50 60 pF1KE0 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 310 320 330 340 350 360 370 380 pF1KE0 QPPQGQNGSMLPNQPSGYRVAGYETQ :::::::::::::::::::::::::: CCDS19 QPPQGQNGSMLPNQPSGYRVAGYETQ 370 380 >>CCDS1900.1 TIA1 gene_id:7072|Hs108|chr2 (375 aa) initn: 2004 init1: 2004 opt: 2010 Z-score: 1653.6 bits: 314.7 E(32554): 8.7e-86 Smith-Waterman score: 2592; 96.9% identity (97.2% similar) in 386 aa overlap (1-386:1-375) 10 20 30 40 50 60 pF1KE0 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE :::::::::::::::::::::::::::::::: .:::::::::::::::: CCDS19 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTS-----------NHFHVFVGDLSPEITTE 70 80 90 100 130 140 150 160 170 180 pF1KE0 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 290 300 310 320 330 340 370 380 pF1KE0 QPPQGQNGSMLPNQPSGYRVAGYETQ :::::::::::::::::::::::::: CCDS19 QPPQGQNGSMLPNQPSGYRVAGYETQ 350 360 370 >>CCDS31295.1 TIAL1 gene_id:7073|Hs108|chr10 (392 aa) initn: 1637 init1: 1163 opt: 1697 Z-score: 1398.7 bits: 267.6 E(32554): 1.4e-71 Smith-Waterman score: 1962; 74.0% identity (84.1% similar) in 408 aa overlap (1-386:2-392) 10 20 30 40 pF1KE0 MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD---------TAG----- :::. .:.:::::::::::::.:::::::::::::.:::: . ..: CCDS31 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 ---NDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR :::::::::.::: :::::::::::::.:::::::::::::::::::: CCDS31 HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTS--------- 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE .:::::::::::::::::::.::::::.:::::::::::::::::::::::.:: ::: CCDS31 --NHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 120 130 140 150 160 170 180 190 200 210 220 pF1KE0 NAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGV ::: .:::::::::::::::::::::::::: :.::::: ...:::::::.::::::::. CCDS31 NAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGI 170 180 190 200 210 220 230 240 250 260 270 280 pF1KE0 TSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC .::::.::::::::::::::::::::.::::::::..::::::::::::::::::::::: CCDS31 ASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKC 230 240 250 260 270 280 290 300 310 320 330 340 pF1KE0 YWGKETLDMINPVQQQNQIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQ :::::. :: . : :. : : .:::.: ::: :: :::: :::::: ::.::: ::: CCDS31 YWGKESPDMTKNFQ---QVDYSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQ 290 300 310 320 330 340 350 360 370 380 pF1KE0 QGFNQTQS-SAPWMGPNYGVQPPQGQNGSML---PNQPSGYRVAGYETQ :::. :: :: ::: ..:.:::::: . ::: .:: .:.:.:: CCDS31 QGFGVDQSPSAAWMG-GFGAQPPQGQAPPPVIPPPNQ-AGYGMASYQTQ 350 360 370 380 390 >>CCDS7613.1 TIAL1 gene_id:7073|Hs108|chr10 (375 aa) initn: 1450 init1: 1163 opt: 1516 Z-score: 1251.6 bits: 240.3 E(32554): 2.1e-63 Smith-Waterman score: 2004; 77.0% identity (87.5% similar) in 391 aa overlap (1-386:2-375) 10 20 30 40 50 pF1KE0 MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRH :::. .:.:::::::::::::.:::::::::::::.:::: . ..:::::::::.::: CCDS76 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 AAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEIT :::::::::::::.:::::::::::::::::::: .:::::::::::::: CCDS76 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTS-----------NHFHVFVGDLSPEIT 70 80 90 100 120 130 140 150 160 170 pF1KE0 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR :::::.::::::.:::::::::::::::::::::::.:: :::::: .:::::::::::: CCDS76 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 TNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFG :::::::::::::: :.::::: ...:::::::.::::::::..::::.::::::::::: CCDS76 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 QIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQN :::::::::.::::::::..::::::::::::::::::::::::::::. :: . : CCDS76 QIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQ--- 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 QIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPN :. : : .:::.: ::: :: :::: :::::: ::.::: ::::::. :: :: ::: . CCDS76 QVDYSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-G 290 300 310 320 330 340 360 370 380 pF1KE0 YGVQPPQGQNGSML---PNQPSGYRVAGYETQ .:.:::::: . ::: .:: .:.:.:: CCDS76 FGAQPPQGQAPPPVIPPPNQ-AGYGMASYQTQ 350 360 370 >>CCDS9311.1 PABPC3 gene_id:5042|Hs108|chr13 (631 aa) initn: 264 init1: 152 opt: 413 Z-score: 351.5 bits: 74.5 E(32554): 3e-13 Smith-Waterman score: 419; 25.9% identity (55.9% similar) in 401 aa overlap (9-386:101-482) 10 20 30 pF1KE0 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKM ..: ::...... . . : .: .:.. CCDS93 TMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNV 80 90 100 110 120 130 40 50 60 70 80 90 pF1KE0 IMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVS . : :. : ::.:. :. : :. ::: . :..: :. : :. . . CCDS93 VCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVG-------QFKSRKEREAEL 140 150 160 170 180 100 110 120 130 140 150 pF1KE0 TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW :... .:.. ... .. : .: :. :: ...:. : .:::::.::::: . CCDS93 GARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHE 190 200 210 220 230 240 160 170 180 190 200 210 pF1KE0 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC ::..:...:.:. :.:.:: .. : .: .. . . .:.. :... . ..: CCDS93 DAQKAVDEMNGKELNGKQIYVGRAQKKVER-QTELKRTFEQMKQDRITRYQV---VNLYV 250 260 270 280 290 220 230 240 250 260 270 pF1KE0 GGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNGTTI .. .:. .. .:..::::: : .:. . ::..:: :.: : :..:.. .:: . CCDS93 KNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIV 300 310 320 330 340 350 280 290 300 310 320 pF1KE0 EGHVV-----------KCYWGKETLDMINPVQQQNQIGYPQPYGQWGQWYGNAQQIGQYM . . . : .: .. . :. . : : : . ..:. . :. CCDS93 ATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAP-PSGYFMTAVPQTQNHAAYY 360 370 380 390 400 410 330 340 350 360 370 pF1KE0 PNGWQVPAYGMYGQAWNQQGFN----QTQSSAPWMG----PNYGVQPPQGQNGSMLPNQP : . :. : . :. :: :.. :: : : ..: ..: .: CCDS93 PPS-QI-ARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQ----VPRVM 420 430 440 450 460 470 380 pF1KE0 SGYRVAGYETQ : :::. :: CCDS93 STQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLA 480 490 500 510 520 530 386 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:46:17 2016 done: Wed Nov 2 18:46:17 2016 Total Scan time: 1.810 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]