FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0665, 240 aa 1>>>pF1KE0665 240 - 240 aa - 240 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7986+/-0.000981; mu= 9.9663+/- 0.059 mean_var=189.2424+/-37.808, 0's: 0 Z-trim(111.8): 31 B-trim: 0 in 0/51 Lambda= 0.093232 statistics sampled from 12679 (12699) to 12679 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.39), width: 16 Scan time: 2.090 The best scores are: opt bits E(32554) CCDS13694.1 U2AF1 gene_id:7307|Hs108|chr21 ( 240) 1677 237.2 7.3e-63 CCDS82649.1 U2AF1L5 gene_id:102724594|Hs108|chr21 ( 240) 1677 237.2 7.3e-63 CCDS33574.1 U2AF1 gene_id:7307|Hs108|chr21 ( 240) 1638 232.0 2.8e-61 CCDS82650.1 U2AF1L5 gene_id:102724594|Hs108|chr21 ( 240) 1638 232.0 2.8e-61 CCDS82648.1 U2AF1L5 gene_id:102724594|Hs108|chr21 ( 167) 1180 170.2 7.7e-43 CCDS42948.1 U2AF1 gene_id:7307|Hs108|chr21 ( 167) 1180 170.2 7.7e-43 CCDS42551.1 U2AF1L4 gene_id:199746|Hs108|chr19 ( 181) 680 103.0 1.4e-22 CCDS14172.1 ZRSR2 gene_id:8233|Hs108|chrX ( 482) 444 71.7 9.5e-13 >>CCDS13694.1 U2AF1 gene_id:7307|Hs108|chr21 (240 aa) initn: 1677 init1: 1677 opt: 1677 Z-score: 1242.1 bits: 237.2 E(32554): 7.3e-63 Smith-Waterman score: 1677; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 >>CCDS82649.1 U2AF1L5 gene_id:102724594|Hs108|chr21 (240 aa) initn: 1677 init1: 1677 opt: 1677 Z-score: 1242.1 bits: 237.2 E(32554): 7.3e-63 Smith-Waterman score: 1677; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 >>CCDS33574.1 U2AF1 gene_id:7307|Hs108|chr21 (240 aa) initn: 1638 init1: 1638 opt: 1638 Z-score: 1213.7 bits: 232.0 E(32554): 2.8e-61 Smith-Waterman score: 1638; 97.1% identity (98.8% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ :::::::::::::::::::::::::::::::::::::::::::::: . :::::::::.: CCDS33 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE .::: .:::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TADGSHCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 >>CCDS82650.1 U2AF1L5 gene_id:102724594|Hs108|chr21 (240 aa) initn: 1638 init1: 1638 opt: 1638 Z-score: 1213.7 bits: 232.0 E(32554): 2.8e-61 Smith-Waterman score: 1638; 97.1% identity (98.8% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ :::::::::::::::::::::::::::::::::::::::::::::: . :::::::::.: CCDS82 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE .::: .:::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TADGSHCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 190 200 210 220 230 240 >>CCDS82648.1 U2AF1L5 gene_id:102724594|Hs108|chr21 (167 aa) initn: 1180 init1: 1180 opt: 1180 Z-score: 882.6 bits: 170.2 E(32554): 7.7e-43 Smith-Waterman score: 1180; 100.0% identity (100.0% similar) in 167 aa overlap (74-240:1-167) 50 60 70 80 90 100 pF1KE0 QTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCD :::::::::::::::::::::::::::::: CCDS82 MQEHYDEFFEEVFTEMEEKYGEVEEMNVCD 10 20 30 110 120 130 140 150 160 pF1KE0 NLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 NLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGEC 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 TRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGG 100 110 120 130 140 150 230 240 pF1KE0 RERDRRRSRDRERSGRF ::::::::::::::::: CCDS82 RERDRRRSRDRERSGRF 160 >>CCDS42948.1 U2AF1 gene_id:7307|Hs108|chr21 (167 aa) initn: 1180 init1: 1180 opt: 1180 Z-score: 882.6 bits: 170.2 E(32554): 7.7e-43 Smith-Waterman score: 1180; 100.0% identity (100.0% similar) in 167 aa overlap (74-240:1-167) 50 60 70 80 90 100 pF1KE0 QTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCD :::::::::::::::::::::::::::::: CCDS42 MQEHYDEFFEEVFTEMEEKYGEVEEMNVCD 10 20 30 110 120 130 140 150 160 pF1KE0 NLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGEC 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 TRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGG 100 110 120 130 140 150 230 240 pF1KE0 RERDRRRSRDRERSGRF ::::::::::::::::: CCDS42 RERDRRRSRDRERSGRF 160 >>CCDS42551.1 U2AF1L4 gene_id:199746|Hs108|chr19 (181 aa) initn: 688 init1: 666 opt: 680 Z-score: 518.7 bits: 103.0 E(32554): 1.4e-22 Smith-Waterman score: 892; 64.2% identity (74.8% similar) in 218 aa overlap (1-212:1-179) 10 20 30 40 50 60 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQ :::::::::::::::::::::::::.:::::::::::::::::: CCDS42 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQ---------------- 10 20 30 40 70 80 90 100 110 120 pF1KE0 SADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRRE :::::..:::::.:::::::::::::::::::::::: CCDS42 -----------------------EVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRRE 50 60 70 80 130 140 150 160 170 180 pF1KE0 EDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRE ::.:.:: .:.::::::: .:.::::::::::.:::::::::::::::::::::.:::.. CCDS42 EDGERAVAELSNRWFNGQAVHGELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISQN 90 100 110 120 130 140 190 200 210 220 230 pF1KE0 LRRELYGR--RRK---KHRSRSRSRERRSR-SRDRGRGGGGGGGGGGGGRERDRRRSRDR :.:.:::: ::. . .. . ::: : : :. .: CCDS42 LQRQLYGRGPRRRSPPRFHTGHHPRERNHRCSPDHWHGRF 150 160 170 180 240 pF1KE0 ERSGRF >>CCDS14172.1 ZRSR2 gene_id:8233|Hs108|chrX (482 aa) initn: 475 init1: 230 opt: 444 Z-score: 342.3 bits: 71.7 E(32554): 9.5e-13 Smith-Waterman score: 461; 35.1% identity (60.3% similar) in 239 aa overlap (12-234:166-403) 10 20 30 40 pF1KE0 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPT :::..:: :: : :::: :::::: :: :: CCDS14 LQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFPT 140 150 160 170 180 190 50 60 70 80 90 pF1KE0 FSQTIALLNIYRN---PQNSSQSAD-GLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVE : :. . ... . : .. : :. : ... .:.:.:. :... :.: CCDS14 SSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYEDVLPEFKN-VGKVI 200 210 220 230 240 250 100 110 120 130 140 150 pF1KE0 EMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQ ...: :: :: :::::... ::. . :. .:.::. :. .. :. ::: .. : : CCDS14 QFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGL 260 270 280 290 300 310 160 170 180 190 200 pF1KE0 YEMGECTRGGFCNFMHL--KPISR--ELRRELYGRRRKKHRSRSRSRERRSR-------- .:. .: :: :::.:. .: .. : :..: . : ... ::: : CCDS14 FEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYY 320 330 340 350 360 370 210 220 230 240 pF1KE0 SRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF :: ::: . . . . : .:. :: : CCDS14 SRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRS 380 390 400 410 420 430 240 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:19:16 2016 done: Wed Nov 2 18:19:17 2016 Total Scan time: 2.090 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]