FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0666, 357 aa 1>>>pF1KE0666 357 - 357 aa - 357 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0961+/-0.000419; mu= 7.9625+/- 0.027 mean_var=376.6956+/-79.968, 0's: 0 Z-trim(122.6): 27 B-trim: 2051 in 1/53 Lambda= 0.066081 statistics sampled from 41067 (41094) to 41067 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.482), width: 16 Scan time: 9.380 The best scores are: opt bits E(85289) XP_016876139 (OMIM: 612408) PREDICTED: paraspeckle ( 393) 2391 241.6 2.3e-63 XP_011533444 (OMIM: 612408) PREDICTED: paraspeckle ( 406) 2335 236.2 9.5e-62 XP_011533443 (OMIM: 612408) PREDICTED: paraspeckle ( 409) 2335 236.2 9.5e-62 XP_011533439 (OMIM: 612408) PREDICTED: paraspeckle ( 469) 2336 236.4 9.6e-62 XP_011533442 (OMIM: 612408) PREDICTED: paraspeckle ( 417) 2335 236.3 9.6e-62 XP_011533441 (OMIM: 612408) PREDICTED: paraspeckle ( 417) 2335 236.3 9.6e-62 XP_011533440 (OMIM: 612408) PREDICTED: paraspeckle ( 447) 2335 236.3 1e-61 NP_001035879 (OMIM: 612408) paraspeckle component ( 523) 2336 236.5 1e-61 XP_006719907 (OMIM: 612408) PREDICTED: paraspeckle ( 523) 2336 236.5 1e-61 NP_001138880 (OMIM: 300084,300967) non-POU domain- ( 471) 1655 171.5 3.4e-42 NP_001138881 (OMIM: 300084,300967) non-POU domain- ( 471) 1655 171.5 3.4e-42 NP_031389 (OMIM: 300084,300967) non-POU domain-con ( 471) 1655 171.5 3.4e-42 XP_005271172 (OMIM: 605199) PREDICTED: splicing fa ( 669) 1638 170.1 1.2e-41 XP_011540252 (OMIM: 605199) PREDICTED: splicing fa ( 679) 1638 170.1 1.3e-41 XP_016857542 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1638 170.2 1.3e-41 NP_005057 (OMIM: 605199) splicing factor, proline- ( 707) 1638 170.2 1.3e-41 XP_016857543 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1638 170.2 1.3e-41 XP_005271169 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1638 170.2 1.3e-41 XP_005271170 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1638 170.2 1.3e-41 NP_001138882 (OMIM: 300084,300967) non-POU domain- ( 382) 1427 149.6 1e-35 >>XP_016876139 (OMIM: 612408) PREDICTED: paraspeckle com (393 aa) initn: 2391 init1: 2391 opt: 2391 Z-score: 1258.6 bits: 241.6 E(85289): 2.3e-63 Smith-Waterman score: 2391; 100.0% identity (100.0% similar) in 357 aa overlap (1-357:37-393) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_016 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG ::::::::::::::::::::::::::: XP_016 REQEELRRQQEGFKPNYMENGDKRKCG 370 380 390 >>XP_011533444 (OMIM: 612408) PREDICTED: paraspeckle com (406 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 1229.6 bits: 236.2 E(85289): 9.5e-62 Smith-Waterman score: 2335; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:37-386) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_011 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: XP_011 REQEELRRQQEGFKPNYMENRWGLDMLPRLGSSSPLSSSS 370 380 390 400 >>XP_011533443 (OMIM: 612408) PREDICTED: paraspeckle com (409 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 1229.6 bits: 236.2 E(85289): 9.5e-62 Smith-Waterman score: 2335; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:37-386) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_011 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: XP_011 REQEELRRQQEGFKPNYMENFKGRNQMVSVQLVQVMSKVDFLC 370 380 390 400 >>XP_011533439 (OMIM: 612408) PREDICTED: paraspeckle com (469 aa) initn: 2490 init1: 2336 opt: 2336 Z-score: 1229.5 bits: 236.4 E(85289): 9.6e-62 Smith-Waterman score: 2336; 99.2% identity (99.7% similar) in 353 aa overlap (1-353:37-389) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_011 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: .. XP_011 REQEELRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNM 370 380 390 400 410 420 >>XP_011533442 (OMIM: 612408) PREDICTED: paraspeckle com (417 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 1229.5 bits: 236.3 E(85289): 9.6e-62 Smith-Waterman score: 2335; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:37-386) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_011 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: XP_011 REQEELRRQQEGFKPNYMENVYLMSFHLKWVIKENVAEVTRSSACSVIQKS 370 380 390 400 410 >>XP_011533441 (OMIM: 612408) PREDICTED: paraspeckle com (417 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 1229.5 bits: 236.3 E(85289): 9.6e-62 Smith-Waterman score: 2335; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:37-386) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_011 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: XP_011 REQEELRRQQEGFKPNYMENVYLMSFHLKWVIKENVAEVTRSSACSVIQKS 370 380 390 400 410 >>XP_011533440 (OMIM: 612408) PREDICTED: paraspeckle com (447 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 1229.2 bits: 236.3 E(85289): 1e-61 Smith-Waterman score: 2335; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:37-386) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_011 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: XP_011 REQEELRRQQEGFKPNYMENYVCHFLITGYTSNSEVVFPSEEFMPNGAAEERILTEVGHQ 370 380 390 400 410 420 >>NP_001035879 (OMIM: 612408) paraspeckle component 1 [H (523 aa) initn: 2478 init1: 2336 opt: 2336 Z-score: 1229.1 bits: 236.5 E(85289): 1e-61 Smith-Waterman score: 2336; 99.2% identity (99.7% similar) in 353 aa overlap (1-353:37-389) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: NP_001 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: .. NP_001 REQEELRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNM 370 380 390 400 410 420 >>XP_006719907 (OMIM: 612408) PREDICTED: paraspeckle com (523 aa) initn: 2478 init1: 2336 opt: 2336 Z-score: 1229.1 bits: 236.5 E(85289): 1e-61 Smith-Waterman score: 2336; 99.2% identity (99.7% similar) in 353 aa overlap (1-353:37-389) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTID :::::::::::::::::::::::::::::: XP_006 LKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTID 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLES 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRH 310 320 330 340 350 360 340 350 pF1KE0 REQEELRRQQEGFKPNYMENGDKRKCG :::::::::::::::::::: .. XP_006 REQEELRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNM 370 380 390 400 410 420 >>NP_001138880 (OMIM: 300084,300967) non-POU domain-cont (471 aa) initn: 1971 init1: 1594 opt: 1655 Z-score: 878.6 bits: 171.5 E(85289): 3.4e-42 Smith-Waterman score: 1655; 71.1% identity (90.9% similar) in 339 aa overlap (9-347:37-374) 10 20 30 pF1KE0 MALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG : :: :: .. ... :.:::.:.: ::: NP_001 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK :::.::: :::::::: :::::....:::.::. .::::..:.::::::::.:::::::: NP_001 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR .:::. :... ::.::: :.:.:::.:: :::::::.::: :: ::.:::.:::::: NP_001 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ .:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.:: NP_001 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE .::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: :::::::: NP_001 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR ::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .:: NP_001 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR 310 320 330 340 350 360 340 350 pF1KE0 QQEGFKPNYMENGDKRKCG :::::: .. NP_001 QQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMMPDGTL 370 380 390 400 410 420 357 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:29:21 2016 done: Sat Nov 5 13:29:22 2016 Total Scan time: 9.380 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]