Result of FASTA (omim) for pF1KE0668
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0668, 393 aa
  1>>>pF1KE0668 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9222+/-0.000471; mu= 1.6782+/- 0.029
 mean_var=553.4146+/-124.471, 0's: 0 Z-trim(120.2): 1403  B-trim: 33 in 1/53
 Lambda= 0.054519
 statistics sampled from 33032 (35219) to 33032 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.413), width:  16
 Scan time:  9.680

The best scores are:                                      opt bits E(85289)
NP_002746 (OMIM: 163950,176872,615279) dual specif ( 393) 2625 221.5 2.8e-57
XP_011520085 (OMIM: 163950,176872,615279) PREDICTE ( 371) 2444 207.2 5.2e-53
NP_109587 (OMIM: 601263,615280) dual specificity m ( 400) 2130 182.6 1.5e-45
XP_016882478 (OMIM: 601263,615280) PREDICTED: dual ( 512) 1861 161.6 3.9e-39
XP_016877901 (OMIM: 163950,176872,615279) PREDICTE ( 345) 1510 133.7 6.6e-31
XP_016877900 (OMIM: 163950,176872,615279) PREDICTE ( 367) 1510 133.7 6.8e-31
XP_016877902 (OMIM: 163950,176872,615279) PREDICTE ( 217) 1390 123.9 3.6e-28
XP_016882480 (OMIM: 601263,615280) PREDICTED: dual ( 252) 1270 114.6 2.7e-25
XP_006722862 (OMIM: 601263,615280) PREDICTED: dual ( 307) 1268 114.6 3.3e-25
XP_016882479 (OMIM: 601263,615280) PREDICTED: dual ( 419) 1270 115.0 3.5e-25
NP_001193733 (OMIM: 602520) dual specificity mitog ( 412)  808 78.6   3e-14
NP_660143 (OMIM: 602520) dual specificity mitogen- ( 448)  808 78.7 3.1e-14
NP_002748 (OMIM: 602520) dual specificity mitogen- ( 438)  761 75.0   4e-13
NP_002749 (OMIM: 601254) dual specificity mitogen- ( 334)  636 64.9 3.2e-10
XP_011523328 (OMIM: 601254) PREDICTED: dual specif ( 337)  636 64.9 3.2e-10
XP_011523327 (OMIM: 601254) PREDICTED: dual specif ( 345)  636 64.9 3.2e-10
NP_003001 (OMIM: 601335) dual specificity mitogen- ( 399)  612 63.2 1.3e-09
NP_001268364 (OMIM: 601335) dual specificity mitog ( 410)  612 63.2 1.3e-09
XP_005256780 (OMIM: 602315) PREDICTED: dual specif ( 318)  608 62.7 1.4e-09
NP_002747 (OMIM: 602315) dual specificity mitogen- ( 318)  608 62.7 1.4e-09
XP_016880348 (OMIM: 602315) PREDICTED: dual specif ( 318)  608 62.7 1.4e-09
XP_011522261 (OMIM: 602315) PREDICTED: dual specif ( 318)  608 62.7 1.4e-09
NP_001303261 (OMIM: 602315) dual specificity mitog ( 318)  608 62.7 1.4e-09
XP_016880347 (OMIM: 602315) PREDICTED: dual specif ( 318)  608 62.7 1.4e-09
XP_016880346 (OMIM: 602315) PREDICTED: dual specif ( 343)  608 62.7 1.5e-09
NP_659731 (OMIM: 602315) dual specificity mitogen- ( 347)  608 62.8 1.5e-09
XP_011522260 (OMIM: 602315) PREDICTED: dual specif ( 298)  601 62.1   2e-09
XP_005257573 (OMIM: 601254) PREDICTED: dual specif ( 278)  600 62.0 2.1e-09
XP_006722038 (OMIM: 601254) PREDICTED: dual specif ( 278)  600 62.0 2.1e-09
NP_001317379 (OMIM: 601254) dual specificity mitog ( 278)  600 62.0 2.1e-09
XP_011523329 (OMIM: 601254) PREDICTED: dual specif ( 278)  600 62.0 2.1e-09
NP_660186 (OMIM: 603014) dual specificity mitogen- ( 419)  590 61.5 4.4e-09
NP_001284484 (OMIM: 603014) dual specificity mitog ( 435)  590 61.5 4.5e-09
XP_005256810 (OMIM: 601335) PREDICTED: dual specif ( 281)  569 59.5 1.1e-08
XP_011522278 (OMIM: 601335) PREDICTED: dual specif ( 319)  567 59.5 1.3e-08
NP_001284485 (OMIM: 603014) dual specificity mitog ( 426)  556 58.8 2.8e-08
XP_006722863 (OMIM: 603014) PREDICTED: dual specif ( 442)  556 58.8 2.9e-08
XP_005256812 (OMIM: 601335) PREDICTED: dual specif ( 253)  513 55.0 2.3e-07
XP_011522279 (OMIM: 601335) PREDICTED: dual specif ( 253)  513 55.0 2.3e-07
XP_016883522 (OMIM: 604965,614868) PREDICTED: seri ( 388)  510 55.1 3.3e-07
XP_005260590 (OMIM: 604965,614868) PREDICTED: seri ( 462)  510 55.3 3.6e-07
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487)  510 55.3 3.7e-07
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456)  509 55.2 3.8e-07
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519)  510 55.3 3.8e-07
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524)  510 55.3 3.8e-07
NP_006272 (OMIM: 605030) serine/threonine-protein  ( 491)  509 55.2 3.9e-07
XP_016869250 (OMIM: 605030) PREDICTED: serine/thre ( 403)  507 54.9   4e-07
XP_011515550 (OMIM: 605030) PREDICTED: serine/thre ( 576)  510 55.4   4e-07
XP_016869245 (OMIM: 605030) PREDICTED: serine/thre ( 580)  510 55.4   4e-07
XP_011515553 (OMIM: 605030) PREDICTED: serine/thre ( 522)  509 55.3   4e-07


>>NP_002746 (OMIM: 163950,176872,615279) dual specificit  (393 aa)
 initn: 2625 init1: 2625 opt: 2625  Z-score: 1149.4  bits: 221.5 E(85289): 2.8e-57
Smith-Waterman score: 2625; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)

               10        20        30        40        50        60
pF1KE0 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
              310       320       330       340       350       360

              370       380       390   
pF1KE0 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
       :::::::::::::::::::::::::::::::::
NP_002 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
              370       380       390   

>>XP_011520085 (OMIM: 163950,176872,615279) PREDICTED: d  (371 aa)
 initn: 2444 init1: 2444 opt: 2444  Z-score: 1072.6  bits: 207.2 E(85289): 5.2e-53
Smith-Waterman score: 2444; 100.0% identity (100.0% similar) in 366 aa overlap (28-393:6-371)

               10        20        30        40        50        60
pF1KE0 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
                                  :::::::::::::::::::::::::::::::::
XP_011                       MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
                                     10        20        30        

               70        80        90       100       110       120
pF1KE0 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
       40        50        60        70        80        90        

              130       140       150       160       170       180
pF1KE0 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
      100       110       120       130       140       150        

              190       200       210       220       230       240
pF1KE0 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
      160       170       180       190       200       210        

              250       260       270       280       290       300
pF1KE0 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
      220       230       240       250       260       270        

              310       320       330       340       350       360
pF1KE0 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
      280       290       300       310       320       330        

              370       380       390   
pF1KE0 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
       :::::::::::::::::::::::::::::::::
XP_011 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
      340       350       360       370 

>>NP_109587 (OMIM: 601263,615280) dual specificity mitog  (400 aa)
 initn: 2120 init1: 1539 opt: 2130  Z-score: 938.9  bits: 182.6 E(85289): 1.5e-45
Smith-Waterman score: 2130; 80.4% identity (92.0% similar) in 398 aa overlap (1-391:2-399)

                  10         20        30        40        50      
pF1KE0  MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
        . ..::. : . .::.  .: . .. ...:.::  ::::::::::::::.:::::::::
NP_109 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE0 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
       : :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
NP_109 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE0 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
       ::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
NP_109 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KE0 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
       :.::::::.:::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_109 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
              190       200       210       220       230       240

        240       250       260       270           280       290  
pF1KE0 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQV----EGDAAETPPRPRT
       :::::::::::::::::::.:::::::::::::::: .::  :    ::.     :::: 
NP_109 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
              250       260       270       280       290       300

            300       310       320       330       340       350  
pF1KE0 PGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADL
       ::::.:..:::::: :::::::::::::::::::.:::. .::.::::::::::::::::
NP_109 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
              310       320       330       340       350       360

            360       370       380       390   
pF1KE0 KQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
       :.:  :.:::::..::::::::::.:. ::::.:::..:  
NP_109 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV 
              370       380       390       400 

>>XP_016882478 (OMIM: 601263,615280) PREDICTED: dual spe  (512 aa)
 initn: 1539 init1: 1539 opt: 1861  Z-score: 823.6  bits: 161.6 E(85289): 3.9e-39
Smith-Waterman score: 1861; 81.0% identity (91.6% similar) in 347 aa overlap (1-340:2-348)

                  10         20        30        40        50      
pF1KE0  MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
        . ..::. : . .::.  .: . .. ...:.::  ::::::::::::::.:::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE0 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
       : :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE0 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
       ::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KE0 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
       :.::::::.:::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
              190       200       210       220       230       240

        240       250       260       270           280       290  
pF1KE0 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQV----EGDAAETPPRPRT
       :::::::::::::::::::.:::::::::::::::: .::  :    ::.     :::: 
XP_016 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
              250       260       270       280       290       300

            300       310       320       330       340       350  
pF1KE0 PGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADL
       ::::.:..:::::: :::::::::::::::::::.:::. .::.::::            
XP_016 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKWFWEGRQPHSIL
              310       320       330       340       350       360

            360       370       380       390                      
pF1KE0 KQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV                   
                                                                   
XP_016 LPPSTQQHLWRGLHRHVPQTTGKELRTPRCPQGRSMCVSSGRRGTAPHSWCRSCPGPLAC
              370       380       390       400       410       420

>>XP_016877901 (OMIM: 163950,176872,615279) PREDICTED: d  (345 aa)
 initn: 2267 init1: 1506 opt: 1510  Z-score: 675.9  bits: 133.7 E(85289): 6.6e-31
Smith-Waterman score: 2219; 92.9% identity (92.9% similar) in 366 aa overlap (28-393:6-345)

               10        20        30        40        50        60
pF1KE0 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
                                  :::::::::::::::::::::::::::::::::
XP_016                       MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
                                     10        20        30        

               70        80        90       100       110       120
pF1KE0 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
       40        50        60        70        80        90        

              130       140       150       160       170       180
pF1KE0 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
       ::::::::::::::::::::::::::                          ::::::::
XP_016 CNSPYIVGFYGAFYSDGEISICMEHM--------------------------VIKGLTYL
      100       110       120                                 130  

              190       200       210       220       230       240
pF1KE0 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
            140       150       160       170       180       190  

              250       260       270       280       290       300
pF1KE0 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
            200       210       220       230       240       250  

              310       320       330       340       350       360
pF1KE0 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
            260       270       280       290       300       310  

              370       380       390   
pF1KE0 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
       :::::::::::::::::::::::::::::::::
XP_016 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
            320       330       340     

>>XP_016877900 (OMIM: 163950,176872,615279) PREDICTED: d  (367 aa)
 initn: 2448 init1: 1506 opt: 1510  Z-score: 675.7  bits: 133.7 E(85289): 6.8e-31
Smith-Waterman score: 2400; 93.4% identity (93.4% similar) in 393 aa overlap (1-393:1-367)

               10        20        30        40        50        60
pF1KE0 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
       ::::::::::::::::::::::::::                          ::::::::
XP_016 CNSPYIVGFYGAFYSDGEISICMEHM--------------------------VIKGLTYL
              130       140                                 150    

              190       200       210       220       230       240
pF1KE0 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KE0 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KE0 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
          280       290       300       310       320       330    

              370       380       390   
pF1KE0 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
       :::::::::::::::::::::::::::::::::
XP_016 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
          340       350       360       

>>XP_016877902 (OMIM: 163950,176872,615279) PREDICTED: d  (217 aa)
 initn: 1390 init1: 1390 opt: 1390  Z-score: 626.6  bits: 123.9 E(85289): 3.6e-28
Smith-Waterman score: 1390; 98.5% identity (100.0% similar) in 206 aa overlap (188-393:12-217)

       160       170       180       190       200       210       
pF1KE0 AGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLID
                                     ...:::::::::::::::::::::::::::
XP_016                    MVPVHQQFLSKQHNVKPSNILVNSRGEIKLCDFGVSGQLID
                                  10        20        30        40 

       220       230       240       250       260       270       
pF1KE0 SMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC
              50        60        70        80        90       100 

       280       290       300       310       320       330       
pF1KE0 QVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDF
             110       120       130       140       150       160 

       340       350       360       370       380       390   
pF1KE0 VNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
             170       180       190       200       210       

>>XP_016882480 (OMIM: 601263,615280) PREDICTED: dual spe  (252 aa)
 initn: 1227 init1: 1227 opt: 1270  Z-score: 575.1  bits: 114.6 E(85289): 2.7e-25
Smith-Waterman score: 1270; 78.5% identity (90.4% similar) in 251 aa overlap (1-248:2-250)

                  10         20        30        40        50      
pF1KE0  MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
        . ..::. : . .::.  .: . .. ...:.::  ::::::::::::::.:::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE0 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
       : :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE0 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
       ::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KE0 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
       :.::::::.:::::::::::::::::::::::::::::::::::::::::::::.  .  
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMA--ETT
              190       200       210       220       230          

        240       250       260       270       280       290      
pF1KE0 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRP
       :   . : . ::                                                
XP_016 GDSATCQIEPWSSL                                              
      240       250                                                

>>XP_006722862 (OMIM: 601263,615280) PREDICTED: dual spe  (307 aa)
 initn: 1608 init1: 1237 opt: 1268  Z-score: 573.5  bits: 114.6 E(85289): 3.3e-25
Smith-Waterman score: 1455; 62.7% identity (72.8% similar) in 394 aa overlap (1-391:2-306)

                  10         20        30        40        50      
pF1KE0  MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
        . ..::. : . .::.  .: . .. ...:.::  ::::::::::::::.:::::::::
XP_006 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE0 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
       : :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
XP_006 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE0 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
       ::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
XP_006 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KE0 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
       :.::::::.:::::::::::::::::::::::::::::::::::::::::::::.:    
XP_006 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAP----
              190       200       210       220       230          

        240       250       260       270       280       290      
pF1KE0 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRP
                                                                   
XP_006 ------------------------------------------------------------
                                                                   

        300       310       320       330       340       350      
pF1KE0 LSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLM
                                :::::.:::. .::.:::::::::::::::::.: 
XP_006 -------------------------PPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLT
                                 240       250       260       270 

        360       370       380       390   
pF1KE0 VHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
        :.:::::..::::::::::.:. ::::.:::..:  
XP_006 NHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV 
             280       290       300        

>>XP_016882479 (OMIM: 601263,615280) PREDICTED: dual spe  (419 aa)
 initn: 1273 init1: 1251 opt: 1270  Z-score: 573.1  bits: 115.0 E(85289): 3.5e-25
Smith-Waterman score: 1270; 62.9% identity (76.6% similar) in 342 aa overlap (1-326:2-333)

                  10         20        30        40        50      
pF1KE0  MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
        . ..::. : . .::.  .: . .. ...:.::  ::::::::::::::.:::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE0 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
       : :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE0 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
       ::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KE0 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPE-RL
       :.::::::.:::::::::::::::::::::::::::::::::::::::::::::.:  .:
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPPPKL
              190       200       210       220       230       240

         240             250       260           270       280     
pF1KE0 QGTHYS------VQSDIWSMGLSLVEMAVGRYP----IPPPDAKELELMFGCQVEGDAAE
        .  ..      :.. .:           :: :    .::   ..:   .  .:   ...
XP_016 PNGVFTPDFQEFVNKWFWE----------GRQPHSILLPPSTQQHLWRGLHRHVPQTTGK
              250                 260       270       280       290

         290         300       310       320       330       340   
pF1KE0 TPPRPRTP-GRPLS-SYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLI
           :: : :: .  : :  .  : .  .     .   :  ::                 
XP_016 ELRTPRCPQGRSMCVSSGRRGTAPHSWCRSCPGPLACAPAMLPRAWGFIRQLAGVASRLL
              300       310       320       330       340       350

           350       360       370       380       390             
pF1KE0 KNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV          
                                                                   
XP_016 THQAGFPTLFPSHPPAGGCPAPGTKVQRWIPRPLPGGRTEQPLCATLSGRRDPGPLRPRP
              360       370       380       390       400       410




393 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:11:26 2016 done: Wed Nov  2 18:11:28 2016
 Total Scan time:  9.680 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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