FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0671, 258 aa 1>>>pF1KE0671 258 - 258 aa - 258 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1259+/-0.00074; mu= 3.5846+/- 0.045 mean_var=169.2488+/-34.359, 0's: 0 Z-trim(115.3): 26 B-trim: 8 in 1/52 Lambda= 0.098585 statistics sampled from 15863 (15883) to 15863 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.488), width: 16 Scan time: 2.110 The best scores are: opt bits E(32554) CCDS2831.1 CISH gene_id:1154|Hs108|chr3 ( 258) 1763 261.7 3.6e-70 CCDS46834.1 CISH gene_id:1154|Hs108|chr3 ( 275) 1713 254.6 5.2e-68 CCDS9047.1 SOCS2 gene_id:8835|Hs108|chr12 ( 198) 397 67.4 8.8e-12 >>CCDS2831.1 CISH gene_id:1154|Hs108|chr3 (258 aa) initn: 1763 init1: 1763 opt: 1763 Z-score: 1373.3 bits: 261.7 E(32554): 3.6e-70 Smith-Waterman score: 1763; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258) 10 20 30 40 50 60 pF1KE0 MVLCVQGPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 MVLCVQGPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 LDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 KTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 TPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDC 190 200 210 220 230 240 250 pF1KE0 LPLPRRMADYLRQYPFQL :::::::::::::::::: CCDS28 LPLPRRMADYLRQYPFQL 250 >>CCDS46834.1 CISH gene_id:1154|Hs108|chr3 (275 aa) initn: 1713 init1: 1713 opt: 1713 Z-score: 1334.5 bits: 254.6 E(32554): 5.2e-68 Smith-Waterman score: 1713; 100.0% identity (100.0% similar) in 251 aa overlap (8-258:25-275) 10 20 30 40 pF1KE0 MVLCVQGPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFL :::::::::::::::::::::::::::::::::::: CCDS46 MYLEHTSHCPHHDDDTAMDTPLPRPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 EEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGT 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 FLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 VASCTADTRSDSPDPAPTPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VASCTADTRSDSPDPAPTPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSL 190 200 210 220 230 240 230 240 250 pF1KE0 QHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQL ::::::::::::::::::::::::::::::::::: CCDS46 QHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQL 250 260 270 >>CCDS9047.1 SOCS2 gene_id:8835|Hs108|chr12 (198 aa) initn: 540 init1: 383 opt: 397 Z-score: 325.0 bits: 67.4 E(32554): 8.8e-12 Smith-Waterman score: 519; 41.7% identity (65.4% similar) in 211 aa overlap (48-258:14-198) 20 30 40 50 60 70 pF1KE0 GQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYL ::: .: . .. .: . .::.. : CCDS90 MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALREL 10 20 30 40 80 90 100 110 120 130 pF1KE0 RESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSS ..::::::.:..::...:.. ::::::.:::.: .::.:.::::. ::::.:::: :.. CCDS90 GQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGK 50 60 70 80 90 100 140 150 160 170 180 190 pF1KE0 FRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALPMPKEDAPSDPAL ::::: . .. : .:: :...:: : : :. CCDS90 FRLDSIICVKSKLKQFDSVVHLIDYYVQMCK-DKRTG----------------------- 110 120 130 200 210 220 230 240 250 pF1KE0 PAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQ : : .::: :..:. .:: ::::::::.::. .. . :::: :. :::..: :: CCDS90 PEAPRNGTVHLYLTKPL--YTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQ 140 150 160 170 180 190 pF1KE0 L . CCDS90 V 258 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:08:27 2016 done: Wed Nov 2 18:08:28 2016 Total Scan time: 2.110 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]