FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0673, 261 aa 1>>>pF1KE0673 261 - 261 aa - 261 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0541+/-0.000996; mu= 4.4330+/- 0.060 mean_var=257.6015+/-52.367, 0's: 0 Z-trim(112.4): 125 B-trim: 116 in 1/51 Lambda= 0.079910 statistics sampled from 13023 (13151) to 13023 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.404), width: 16 Scan time: 2.540 The best scores are: opt bits E(32554) CCDS47459.1 SRSF12 gene_id:135295|Hs108|chr6 ( 261) 1771 216.7 1.3e-56 CCDS30630.1 SRSF10 gene_id:10772|Hs108|chr1 ( 262) 834 108.7 4.3e-24 CCDS53282.1 SRSF10 gene_id:10772|Hs108|chr1 ( 261) 828 108.0 7e-24 CCDS30629.1 SRSF10 gene_id:10772|Hs108|chr1 ( 183) 734 97.0 1e-20 CCDS53283.1 SRSF10 gene_id:10772|Hs108|chr1 ( 173) 729 96.4 1.5e-20 CCDS72728.1 SRSF10 gene_id:10772|Hs108|chr1 ( 172) 723 95.7 2.3e-20 CCDS53281.1 SRSF10 gene_id:10772|Hs108|chr1 ( 182) 722 95.6 2.6e-20 CCDS53280.1 SRSF10 gene_id:10772|Hs108|chr1 ( 165) 710 94.1 6.4e-20 >>CCDS47459.1 SRSF12 gene_id:135295|Hs108|chr6 (261 aa) initn: 1771 init1: 1771 opt: 1771 Z-score: 1129.8 bits: 216.7 E(32554): 1.3e-56 Smith-Waterman score: 1771; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT 190 200 210 220 230 240 250 260 pF1KE0 AKHSHFRSHSRSRSYRHKNSW ::::::::::::::::::::: CCDS47 AKHSHFRSHSRSRSYRHKNSW 250 260 >>CCDS30630.1 SRSF10 gene_id:10772|Hs108|chr1 (262 aa) initn: 994 init1: 641 opt: 834 Z-score: 546.0 bits: 108.7 E(32554): 4.3e-24 Smith-Waterman score: 834; 56.6% identity (74.0% similar) in 265 aa overlap (1-261:1-254) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::: ::::::::.::::: :: :::::::::::::::::.::::::::::::::::::: CCDS30 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDHRRSRSPSQRR ::::::::.::.:::.:::::::::::::::::.:::.:: :. : : : . :: CCDS30 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSS--RYDDYDRYRR 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGR .:::: .:::: : . . . : ::: .:: . :::: : .: . : . .:. CCDS30 SRSRS----YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRS--HSDNDRFKHRNRSF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SRSKSLQK-RSKSIGKSQSSSPQKQTS-SGTKSRSHGRHSDSIARSPCKSPKGYTNSETK ::::: .. :::: :.. .. ... : : ::.:. .. .:: .. :: . : . : CCDS30 SRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSK-TDS--KTHYKSGSRYEKESRK 180 190 200 210 220 240 250 260 pF1KE0 VQTAK-HSHFRSHSRSRSYRHKNSW . . .:. ::.::::: .. :: CCDS30 KEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 230 240 250 260 >>CCDS53282.1 SRSF10 gene_id:10772|Hs108|chr1 (261 aa) initn: 678 init1: 678 opt: 828 Z-score: 542.3 bits: 108.0 E(32554): 7e-24 Smith-Waterman score: 828; 55.1% identity (71.5% similar) in 267 aa overlap (1-260:1-258) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::: ::::::::.::::: :: :::::::::::::::::.::::::::::::::::::: CCDS53 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR ::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . :::: CCDS53 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN : : .: :::: :. : ::: : .. : :.:.: . . .:. : .:. CCDS53 SRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDRFKHRNRSFSRSK----- 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 FGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTN : .:::::: : ... .::.: : .. . ::.. . : : .: .: : CCDS53 --SNSRSRSKS-QPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKK-EP 180 190 200 210 220 230 240 250 260 pF1KE0 SETKVQTAKHSHFRSHSRSRSYRHKNSW ..: :. ..:. ::.:::::. .: CCDS53 PRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 240 250 260 >>CCDS30629.1 SRSF10 gene_id:10772|Hs108|chr1 (183 aa) initn: 849 init1: 641 opt: 734 Z-score: 485.5 bits: 97.0 E(32554): 1e-20 Smith-Waterman score: 734; 65.2% identity (77.9% similar) in 181 aa overlap (1-180:1-175) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::: ::::::::.::::: :: :::::::::::::::::.::::::::::::::::::: CCDS30 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDHRRSRSPSQRR ::::::::.::.:::.:::::::::::::::::.:::.:: :. : : : . :: CCDS30 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSS--RYDDYDRYRR 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGR .:::: .:::: : . . . : ::: .:: . :::: : .. : ..... CCDS30 SRSRS----YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQ : CCDS30 SAYYTSRKI 180 >>CCDS53283.1 SRSF10 gene_id:10772|Hs108|chr1 (173 aa) initn: 860 init1: 641 opt: 729 Z-score: 482.7 bits: 96.4 E(32554): 1.5e-20 Smith-Waterman score: 729; 68.2% identity (79.2% similar) in 173 aa overlap (1-165:1-173) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::: ::::::::.::::: :: :::::::::::::::::.::::::::::::::::::: CCDS53 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR ::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . :::: CCDS53 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKESRHR-RFSYSQSKSRSKSLPRRSTSARQSRTPRR : : .: :::: :. : ::: : ..:: : :.:.: . : .. . : CCDS53 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDSQVSKKKNER 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 NFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYT >>CCDS72728.1 SRSF10 gene_id:10772|Hs108|chr1 (172 aa) initn: 873 init1: 641 opt: 723 Z-score: 478.9 bits: 95.7 E(32554): 2.3e-20 Smith-Waterman score: 723; 67.4% identity (78.5% similar) in 172 aa overlap (1-165:1-172) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::: ::::::::.::::: :: :::::::::::::::::.::::::::::::::::::: CCDS72 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR ::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . :::: CCDS72 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN : : .: :::: :. : ::: : .. : :.:.: . : .. . : CCDS72 SRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDSQVSKKKNER 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 FGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTN >>CCDS53281.1 SRSF10 gene_id:10772|Hs108|chr1 (182 aa) initn: 790 init1: 641 opt: 722 Z-score: 478.0 bits: 95.6 E(32554): 2.6e-20 Smith-Waterman score: 722; 64.6% identity (77.9% similar) in 181 aa overlap (1-180:1-174) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::: ::::::::.::::: :: :::::::::::::::::.::::::::::::::::::: CCDS53 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDHRRSRSPSQRR ::::::::.::.:::.:::::::::::::::::.:::.:: :. : : : . :: CCDS53 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSS--RYDDYDRYRR 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGR .:::: .:::: : . . . : ::: ..: . :::: : .. : ..... CCDS53 SRSRS----YERRRSRSRSFDYNYRRSYSP-RNRPTGRPRRSRSHSDNDRPNCSWNTQYS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQ : CCDS53 SAYYTSRKI 180 >>CCDS53280.1 SRSF10 gene_id:10772|Hs108|chr1 (165 aa) initn: 796 init1: 641 opt: 710 Z-score: 471.1 bits: 94.1 E(32554): 6.4e-20 Smith-Waterman score: 713; 69.9% identity (80.4% similar) in 163 aa overlap (1-153:1-163) 10 20 30 40 50 60 pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED :::: ::::::::.::::: :: :::::::::::::::::.::::::::::::::::::: CCDS53 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR ::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . :::: CCDS53 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKE---SRHRRFSYSQSKSRSKSLPRRSTSARQSRTP : : .: :::: :. : ::: : .. : . ..: . :: CCDS53 SRSYERRRSRSRSFDYNYRRSYSPRKPNCSWNTQYSSAYYTSRKI 130 140 150 160 180 190 200 210 220 230 pF1KE0 RRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKG 261 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:21:29 2016 done: Sat Nov 5 18:21:30 2016 Total Scan time: 2.540 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]