FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0673, 261 aa
1>>>pF1KE0673 261 - 261 aa - 261 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2472+/-0.000436; mu= 4.5024+/- 0.028
mean_var=344.3430+/-72.509, 0's: 0 Z-trim(120.4): 180 B-trim: 1702 in 1/57
Lambda= 0.069116
statistics sampled from 35461 (35685) to 35461 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.418), width: 16
Scan time: 7.540
The best scores are: opt bits E(85289)
NP_473357 (OMIM: 605221) serine/arginine-rich spli ( 262) 834 96.3 6e-20
NP_001177934 (OMIM: 605221) serine/arginine-rich s ( 261) 828 95.7 9.1e-20
NP_001287866 (OMIM: 605221) serine/arginine-rich s ( 217) 766 89.4 6e-18
NP_006616 (OMIM: 605221) serine/arginine-rich spli ( 183) 734 86.1 4.9e-17
NP_001177935 (OMIM: 605221) serine/arginine-rich s ( 173) 729 85.6 6.8e-17
NP_001287865 (OMIM: 605221) serine/arginine-rich s ( 172) 723 85.0 1e-16
NP_001177936 (OMIM: 605221) serine/arginine-rich s ( 182) 722 84.9 1.1e-16
NP_001177938 (OMIM: 605221) serine/arginine-rich s ( 165) 710 83.6 2.4e-16
NP_003007 (OMIM: 600813) serine/arginine-rich spli ( 221) 445 57.4 2.6e-08
NP_001182356 (OMIM: 600813) serine/arginine-rich s ( 221) 445 57.4 2.6e-08
XP_016880431 (OMIM: 600813) PREDICTED: serine/argi ( 221) 445 57.4 2.6e-08
XP_005264541 (OMIM: 600572) PREDICTED: serine/argi ( 235) 399 52.8 6.5e-07
NP_001026854 (OMIM: 600572) serine/arginine-rich s ( 238) 390 52.0 1.2e-06
NP_001182375 (OMIM: 600572) serine/arginine-rich s ( 226) 388 51.7 1.4e-06
XP_005264542 (OMIM: 600572) PREDICTED: serine/argi ( 223) 380 50.9 2.3e-06
XP_016872631 (OMIM: 603269) PREDICTED: serine/argi ( 282) 376 50.7 3.5e-06
NP_115285 (OMIM: 603269) serine/arginine-rich spli ( 282) 376 50.7 3.5e-06
NP_003008 (OMIM: 603364) serine/arginine-rich spli ( 164) 333 46.0 5.1e-05
NP_006266 (OMIM: 601944) serine/arginine-rich spli ( 344) 303 43.5 0.00061
NP_008856 (OMIM: 600914) serine/arginine-rich spli ( 272) 265 39.6 0.0074
NP_001307143 (OMIM: 600914) serine/arginine-rich s ( 272) 265 39.6 0.0074
NP_001034554 (OMIM: 600914) serine/arginine-rich s ( 272) 265 39.6 0.0074
>>NP_473357 (OMIM: 605221) serine/arginine-rich splicing (262 aa)
initn: 994 init1: 641 opt: 834 Z-score: 479.1 bits: 96.3 E(85289): 6e-20
Smith-Waterman score: 834; 56.6% identity (74.0% similar) in 265 aa overlap (1-261:1-254)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_473 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDHRRSRSPSQRR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : : . ::
NP_473 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSS--RYDDYDRYRR
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGR
.:::: .:::: : . . . : ::: .:: . :::: : .: . : . .:.
NP_473 SRSRS----YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRS--HSDNDRFKHRNRSF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SRSKSLQK-RSKSIGKSQSSSPQKQTS-SGTKSRSHGRHSDSIARSPCKSPKGYTNSETK
::::: .. :::: :.. .. ... : : ::.:. .. .:: .. :: . : . :
NP_473 SRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSK-TDS--KTHYKSGSRYEKESRK
180 190 200 210 220
240 250 260
pF1KE0 VQTAK-HSHFRSHSRSRSYRHKNSW
. . .:. ::.::::: .. ::
NP_473 KEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH
230 240 250 260
>>NP_001177934 (OMIM: 605221) serine/arginine-rich splic (261 aa)
initn: 678 init1: 678 opt: 828 Z-score: 475.8 bits: 95.7 E(85289): 9.1e-20
Smith-Waterman score: 828; 55.1% identity (71.5% similar) in 267 aa overlap (1-260:1-258)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . ::::
NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN
: : .: :::: :. : ::: : .. : :.:.: . . .:. : .:.
NP_001 SRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDRFKHRNRSFSRSK-----
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 FGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTN
: .:::::: : ... .::.: : .. . ::.. . : : .: .: :
NP_001 --SNSRSRSKS-QPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKK-EP
180 190 200 210 220 230
240 250 260
pF1KE0 SETKVQTAKHSHFRSHSRSRSYRHKNSW
..: :. ..:. ::.:::::. .:
NP_001 PRSKSQSRSQSRSRSKSRSRSWTSPKSSGH
240 250 260
>>NP_001287866 (OMIM: 605221) serine/arginine-rich splic (217 aa)
initn: 955 init1: 641 opt: 766 Z-score: 443.3 bits: 89.4 E(85289): 6e-18
Smith-Waterman score: 781; 63.2% identity (77.4% similar) in 212 aa overlap (1-211:1-198)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDHRRSRSPSQRR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : : . ::
NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSS--RYDDYDRYRR
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGR
.:::: .:::: : . . . : ::: .:: . :::: : .: . : . .:.
NP_001 SRSRS----YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRS--HSDNDRFKHRNRSF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQ
::::: ..::.: ::: :.:. .. ..::
NP_001 SRSKS-NSRSRS--KSQ---PKKEMKAKSRSRPNCSWNTQYSSAYYTSRKI
180 190 200 210
240 250 260
pF1KE0 TAKHSHFRSHSRSRSYRHKNSW
>>NP_006616 (OMIM: 605221) serine/arginine-rich splicing (183 aa)
initn: 849 init1: 641 opt: 734 Z-score: 426.8 bits: 86.1 E(85289): 4.9e-17
Smith-Waterman score: 734; 65.2% identity (77.9% similar) in 181 aa overlap (1-180:1-175)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_006 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDHRRSRSPSQRR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : : . ::
NP_006 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSS--RYDDYDRYRR
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGR
.:::: .:::: : . . . : ::: .:: . :::: : .. : .....
NP_006 SRSRS----YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQ
:
NP_006 SAYYTSRKI
180
>>NP_001177935 (OMIM: 605221) serine/arginine-rich splic (173 aa)
initn: 860 init1: 641 opt: 729 Z-score: 424.3 bits: 85.6 E(85289): 6.8e-17
Smith-Waterman score: 729; 68.2% identity (79.2% similar) in 173 aa overlap (1-165:1-173)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . ::::
NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKESRHR-RFSYSQSKSRSKSLPRRSTSARQSRTPRR
: : .: :::: :. : ::: : ..:: : :.:.: . : .. . :
NP_001 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDSQVSKKKNER
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 NFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYT
>>NP_001287865 (OMIM: 605221) serine/arginine-rich splic (172 aa)
initn: 873 init1: 641 opt: 723 Z-score: 421.1 bits: 85.0 E(85289): 1e-16
Smith-Waterman score: 723; 67.4% identity (78.5% similar) in 172 aa overlap (1-165:1-172)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . ::::
NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN
: : .: :::: :. : ::: : .. : :.:.: . : .. . :
NP_001 SRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDSQVSKKKNER
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 FGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTN
>>NP_001177936 (OMIM: 605221) serine/arginine-rich splic (182 aa)
initn: 790 init1: 641 opt: 722 Z-score: 420.3 bits: 84.9 E(85289): 1.1e-16
Smith-Waterman score: 722; 64.6% identity (77.9% similar) in 181 aa overlap (1-180:1-174)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDHRRSRSPSQRR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : : . ::
NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSS--RYDDYDRYRR
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGR
.:::: .:::: : . . . : ::: ..: . :::: : .. : .....
NP_001 SRSRS----YERRRSRSRSFDYNYRRSYSP-RNRPTGRPRRSRSHSDNDRPNCSWNTQYS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQ
:
NP_001 SAYYTSRKI
180
>>NP_001177938 (OMIM: 605221) serine/arginine-rich splic (165 aa)
initn: 796 init1: 641 opt: 710 Z-score: 414.3 bits: 83.6 E(85289): 2.4e-16
Smith-Waterman score: 713; 69.9% identity (80.4% similar) in 163 aa overlap (1-153:1-163)
10 20 30 40 50 60
pF1KE0 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
:::: ::::::::.::::: :: :::::::::::::::::.:::::::::::::::::::
NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPSDH------RRSR
::::::::.::.:::.:::::::::::::::::.:::.:: :. : : . ::::
NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 SPSQRRTRSRSSSWGRNRRRSDSLKE---SRHRRFSYSQSKSRSKSLPRRSTSARQSRTP
: : .: :::: :. : ::: : .. : . ..: . ::
NP_001 SRSYERRRSRSRSFDYNYRRSYSPRKPNCSWNTQYSSAYYTSRKI
130 140 150 160
180 190 200 210 220 230
pF1KE0 RRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKG
>>NP_003007 (OMIM: 600813) serine/arginine-rich splicing (221 aa)
initn: 646 init1: 285 opt: 445 Z-score: 270.2 bits: 57.4 E(85289): 2.6e-08
Smith-Waterman score: 459; 41.4% identity (63.7% similar) in 237 aa overlap (4-229:3-214)
10 20 30 40 50
pF1KE0 MSRYTRPPN-----TSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAY
: ::: ::: . :.. : :. ::: : .:: . ::::: : ::.. ::::.
NP_003 MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAF
10 20 30 40 50
60 70 80 90 100
pF1KE0 VQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDH------
:.:.: ::::::. .. . ::....:.:. : : . .:.. : : .
NP_003 VRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRP-PDSHHSRRGPP--PRRYGGGGYG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 RRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRT
:::::: .:: :::: : .:.: :: : :.: :.:.::..: :: :. .::.
NP_003 RRSRSP-RRRRRSRSRSRSRSRSRSRS-------RYSRSKSRSRTRS---RSRSTSKSRS
120 130 140 150 160
170 180 190 200 210 220
pF1KE0 PRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPK
:: :...: : : ..::.: ..:.: :: .. .::::. ..:: :::.
NP_003 ARR---SKSKSSSVS-RSRSRSRSRSRSRSPPPVSKRESKSRSR-------SKSPPKSPE
170 180 190 200 210
230 240 250 260
pF1KE0 GYTNSETKVQTAKHSHFRSHSRSRSYRHKNSW
NP_003 EEGAVSS
220
>>NP_001182356 (OMIM: 600813) serine/arginine-rich splic (221 aa)
initn: 646 init1: 285 opt: 445 Z-score: 270.2 bits: 57.4 E(85289): 2.6e-08
Smith-Waterman score: 459; 41.4% identity (63.7% similar) in 237 aa overlap (4-229:3-214)
10 20 30 40 50
pF1KE0 MSRYTRPPN-----TSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAY
: ::: ::: . :.. : :. ::: : .:: . ::::: : ::.. ::::.
NP_001 MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAF
10 20 30 40 50
60 70 80 90 100
pF1KE0 VQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDH------
:.:.: ::::::. .. . ::....:.:. : : . .:.. : : .
NP_001 VRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRP-PDSHHSRRGPP--PRRYGGGGYG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 RRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRT
:::::: .:: :::: : .:.: :: : :.: :.:.::..: :: :. .::.
NP_001 RRSRSP-RRRRRSRSRSRSRSRSRSRS-------RYSRSKSRSRTRS---RSRSTSKSRS
120 130 140 150 160
170 180 190 200 210 220
pF1KE0 PRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPK
:: :...: : : ..::.: ..:.: :: .. .::::. ..:: :::.
NP_001 ARR---SKSKSSSVS-RSRSRSRSRSRSRSPPPVSKRESKSRSR-------SKSPPKSPE
170 180 190 200 210
230 240 250 260
pF1KE0 GYTNSETKVQTAKHSHFRSHSRSRSYRHKNSW
NP_001 EEGAVSS
220
261 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:21:30 2016 done: Sat Nov 5 18:21:31 2016
Total Scan time: 7.540 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]