FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0676, 396 aa 1>>>pF1KE0676 396 - 396 aa - 396 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3262+/-0.00113; mu= 6.8654+/- 0.066 mean_var=155.3411+/-35.567, 0's: 0 Z-trim(106.2): 99 B-trim: 115 in 1/49 Lambda= 0.102904 statistics sampled from 8750 (8847) to 8750 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.272), width: 16 Scan time: 2.500 The best scores are: opt bits E(32554) CCDS9947.1 VRK1 gene_id:7443|Hs108|chr14 ( 396) 2664 407.9 8e-114 CCDS46291.1 VRK2 gene_id:7444|Hs108|chr2 ( 396) 1152 183.5 3e-46 CCDS1859.1 VRK2 gene_id:7444|Hs108|chr2 ( 508) 1152 183.6 3.6e-46 CCDS46292.1 VRK2 gene_id:7444|Hs108|chr2 ( 485) 1121 178.9 8.5e-45 CCDS33076.1 VRK3 gene_id:51231|Hs108|chr19 ( 424) 733 121.3 1.7e-27 CCDS12791.1 VRK3 gene_id:51231|Hs108|chr19 ( 474) 733 121.3 1.8e-27 CCDS77334.1 VRK3 gene_id:51231|Hs108|chr19 ( 412) 659 110.3 3.3e-24 CCDS11806.1 CSNK1D gene_id:1453|Hs108|chr17 ( 409) 427 75.8 7.7e-14 CCDS11805.1 CSNK1D gene_id:1453|Hs108|chr17 ( 415) 427 75.9 7.8e-14 CCDS13970.1 CSNK1E gene_id:1454|Hs108|chr22 ( 416) 419 74.7 1.8e-13 CCDS47303.1 CSNK1A1 gene_id:1452|Hs108|chr5 ( 337) 401 71.9 9.7e-13 CCDS64291.1 CSNK1A1 gene_id:1452|Hs108|chr5 ( 325) 398 71.5 1.3e-12 CCDS9363.1 CSNK1A1L gene_id:122011|Hs108|chr13 ( 337) 385 69.5 5e-12 CCDS59491.1 CSNK1G3 gene_id:1456|Hs108|chr5 ( 424) 383 69.3 7.4e-12 CCDS10192.2 CSNK1G1 gene_id:53944|Hs108|chr15 ( 422) 382 69.2 8.1e-12 CCDS4135.1 CSNK1G3 gene_id:1456|Hs108|chr5 ( 447) 376 68.3 1.6e-11 CCDS43355.1 CSNK1G3 gene_id:1456|Hs108|chr5 ( 455) 376 68.3 1.6e-11 CCDS59492.1 CSNK1G3 gene_id:1456|Hs108|chr5 ( 348) 374 67.9 1.6e-11 CCDS34218.1 CSNK1G3 gene_id:1456|Hs108|chr5 ( 423) 374 68.0 1.9e-11 CCDS12077.1 CSNK1G2 gene_id:1455|Hs108|chr19 ( 415) 373 67.8 2e-11 CCDS59493.1 CSNK1G3 gene_id:1456|Hs108|chr5 ( 311) 369 67.1 2.5e-11 >>CCDS9947.1 VRK1 gene_id:7443|Hs108|chr14 (396 aa) initn: 2664 init1: 2664 opt: 2664 Z-score: 2156.9 bits: 407.9 E(32554): 8e-114 Smith-Waterman score: 2664; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396) 10 20 30 40 50 60 pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK 310 320 330 340 350 360 370 380 390 pF1KE0 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK :::::::::::::::::::::::::::::::::::: CCDS99 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK 370 380 390 >>CCDS46291.1 VRK2 gene_id:7444|Hs108|chr2 (396 aa) initn: 1150 init1: 729 opt: 1152 Z-score: 943.8 bits: 183.5 E(32554): 3e-46 Smith-Waterman score: 1152; 55.4% identity (79.0% similar) in 314 aa overlap (12-324:4-313) 10 20 30 40 50 pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSS . . : .: : :... :: ..: .: ::.:::: :::: :. CCDS46 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKP 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLH :. :: ::::: ..:::::.:::::::.:: . :.:::. ..: :::.: ..:::: CCDS46 EK---DARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLT 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 DKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIK . .:.:::::.:.:.: ::::: :. :...:::::..:.::.::::::.:::::::: CCDS46 EFKGRSYRFMVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 ASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPS :.::::.:::::::::.::::.:::::.: ::.:.:.:.. :.:::::::.:::.::: : CCDS46 AANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 RRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEI ::.:.:::::::..:: :.::::.::::: :. .: ... . . : : .. :: CCDS46 RRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 AKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRK :... .. : : ::: :. :. :: CCDS46 AQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAA 290 300 310 320 330 340 >>CCDS1859.1 VRK2 gene_id:7444|Hs108|chr2 (508 aa) initn: 1183 init1: 729 opt: 1152 Z-score: 942.3 bits: 183.6 E(32554): 3.6e-46 Smith-Waterman score: 1163; 47.3% identity (71.4% similar) in 406 aa overlap (12-396:4-405) 10 20 30 40 50 pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSS . . : .: : :... :: ..: .: ::.:::: :::: :. CCDS18 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKP 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLH :. :: ::::: ..:::::.:::::::.:: . :.:::. ..: :::.: ..:::: CCDS18 EK---DARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLT 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 DKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIK . .:.:::::.:.:.: ::::: :. :...:::::..:.::.::::::.:::::::: CCDS18 EFKGRSYRFMVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 ASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPS :.::::.:::::::::.::::.:::::.: ::.:.:.:.. :.:::::::.:::.::: : CCDS18 AANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 RRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEI ::.:.:::::::..:: :.::::.::::: :. .: ... . . : : .. :: CCDS18 RRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 AKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLK :... .. : : ::: :. :. :: .: : . :. :.. CCDS18 AQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAA 290 300 310 320 330 340 360 370 380 390 pF1KE0 AKTITKKRKKEIEES--KEPGVED-TEWSNTQTE--------EAIQTRSRTRKRVQK .: ..: ... ::.. .: ..:. . :. . : :: : .: :.. :. CCDS18 TKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQE 350 360 370 380 390 400 CCDS18 PLNEVNSFPQKISYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESST 410 420 430 440 450 460 >>CCDS46292.1 VRK2 gene_id:7444|Hs108|chr2 (485 aa) initn: 1157 init1: 729 opt: 1121 Z-score: 917.7 bits: 178.9 E(32554): 8.5e-45 Smith-Waterman score: 1132; 48.4% identity (72.3% similar) in 386 aa overlap (32-396:1-382) 10 20 30 40 50 60 pF1KE0 PRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSSE : ..: .: ::.:::: :::: :. : CCDS46 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPE 10 20 30 70 80 90 100 110 120 pF1KE0 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD . :: ::::: ..:::::.:::::::.:: . :.:::. ..: :::.: ..:::: . CCDS46 K---DARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTE 40 50 60 70 80 130 140 150 160 170 180 pF1KE0 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA .:.:::::.:.:.: ::::: :. :...:::::..:.::.::::::.::::::::: CCDS46 FKGRSYRFMVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIKA 90 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR .::::.:::::::::.::::.:::::.: ::.:.:.:.. :.:::::::.:::.::: :: CCDS46 ANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSR 150 160 170 180 190 200 250 260 270 280 290 300 pF1KE0 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA :.:.:::::::..:: :.::::.::::: :. .: ... . . : : .. ::: CCDS46 RSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIA 210 220 230 240 250 260 310 320 330 340 350 pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLKA ... .. : : ::: :. :. :: .: : . :. :.. . CCDS46 QFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAAT 270 280 290 300 310 320 360 370 380 390 pF1KE0 KTITKKRKKEIEES--KEPGVED-TEWSNTQTE--------EAIQTRSRTRKRVQK : ..: ... ::.. .: ..:. . :. . : :: : .: :.. :. CCDS46 KQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEP 330 340 350 360 370 380 CCDS46 LNEVNSFPQKISYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTG 390 400 410 420 430 440 >>CCDS33076.1 VRK3 gene_id:51231|Hs108|chr19 (424 aa) initn: 659 init1: 502 opt: 733 Z-score: 607.2 bits: 121.3 E(32554): 1.7e-27 Smith-Waterman score: 733; 36.2% identity (65.3% similar) in 334 aa overlap (5-329:85-411) 10 20 30 pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAK .. :. ..: . : : . .: ..:: . CCDS33 PKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSL-EALPTGTVLTDKSG 60 70 80 90 100 110 40 50 60 70 80 90 pF1KE0 KEWKVGLPIGQGGFGCIYLADMNSSESVGSDAP---CVVKVEPSDNGPLFTELKFYQRAA ..::. . . : .: : .:. . : .:.. .: : ::.: .:.:::: CCDS33 RQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD-GRLFNEQNFFQRAA 120 130 140 150 160 170 100 110 120 130 140 pF1KE0 KPEQIQKWIRTRKLKYLGVPKYWGSGLH-DKNGKSYRFMIMDRFGSDLQKIYEANAKR-F :: :..:: . . :..: : :.: :: :::... .: .::. ... :. . CCDS33 KPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK----YRFLVLPSLGRSLQSALDVSPKHVL 180 190 200 210 220 150 160 170 180 190 200 pF1KE0 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGV :...:::.. :.:: ::..::.:::::.. : :.... .. .:: :. ::.:.:::: : CCDS33 SERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGK 230 240 250 260 270 280 210 220 230 240 250 260 pF1KE0 HKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPK : : : . :.: .:: :.: :.: .::::.::. :::::..:: : ::: . : . . CCDS33 HVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTE 290 300 310 320 330 340 270 280 290 300 310 320 pF1KE0 YVRDSKIRYRENIASLMDKCFPEKNKPGE-IAKYMETVKLLDYTEKPLYENLRD---ILL . .: .. .. . .. : . .:.: . ::...: : : ::: : ::. :: CCDS33 DIMKQKQKFVDKPGPFVGPC-GHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALL 350 360 370 380 390 400 330 340 350 360 370 380 pF1KE0 QGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKKEIEESKEPGVEDTEWSNTQTEEAIQ : :. CCDS33 QDLRVSPYDPIGLPMVP 410 420 >>CCDS12791.1 VRK3 gene_id:51231|Hs108|chr19 (474 aa) initn: 659 init1: 502 opt: 733 Z-score: 606.5 bits: 121.3 E(32554): 1.8e-27 Smith-Waterman score: 733; 36.2% identity (65.3% similar) in 334 aa overlap (5-329:135-461) 10 20 30 pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAK .. :. ..: . : : . .: ..:: . CCDS12 PKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSL-EALPTGTVLTDKSG 110 120 130 140 150 160 40 50 60 70 80 90 pF1KE0 KEWKVGLPIGQGGFGCIYLADMNSSESVGSDAP---CVVKVEPSDNGPLFTELKFYQRAA ..::. . . : .: : .:. . : .:.. .: : ::.: .:.:::: CCDS12 RQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD-GRLFNEQNFFQRAA 170 180 190 200 210 220 100 110 120 130 140 pF1KE0 KPEQIQKWIRTRKLKYLGVPKYWGSGLH-DKNGKSYRFMIMDRFGSDLQKIYEANAKR-F :: :..:: . . :..: : :.: :: :::... .: .::. ... :. . CCDS12 KPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK----YRFLVLPSLGRSLQSALDVSPKHVL 230 240 250 260 270 150 160 170 180 190 200 pF1KE0 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGV :...:::.. :.:: ::..::.:::::.. : :.... .. .:: :. ::.:.:::: : CCDS12 SERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGK 280 290 300 310 320 330 210 220 230 240 250 260 pF1KE0 HKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPK : : : . :.: .:: :.: :.: .::::.::. :::::..:: : ::: . : . . CCDS12 HVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTE 340 350 360 370 380 390 270 280 290 300 310 320 pF1KE0 YVRDSKIRYRENIASLMDKCFPEKNKPGE-IAKYMETVKLLDYTEKPLYENLRD---ILL . .: .. .. . .. : . .:.: . ::...: : : ::: : ::. :: CCDS12 DIMKQKQKFVDKPGPFVGPC-GHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALL 400 410 420 430 440 450 330 340 350 360 370 380 pF1KE0 QGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKKEIEESKEPGVEDTEWSNTQTEEAIQ : :. CCDS12 QDLRVSPYDPIGLPMVP 460 470 >>CCDS77334.1 VRK3 gene_id:51231|Hs108|chr19 (412 aa) initn: 596 init1: 439 opt: 659 Z-score: 548.0 bits: 110.3 E(32554): 3.3e-24 Smith-Waterman score: 659; 37.3% identity (66.7% similar) in 276 aa overlap (5-275:135-404) 10 20 30 pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAK .. :. ..: . : : . .: ..:: . CCDS77 PKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSL-EALPTGTVLTDKSG 110 120 130 140 150 160 40 50 60 70 80 90 pF1KE0 KEWKVGLPIGQGGFGCIYLADMNSSESVGSDAP---CVVKVEPSDNGPLFTELKFYQRAA ..::. . . : .: : .:. . : .:.. .: : ::.: .:.:::: CCDS77 RQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD-GRLFNEQNFFQRAA 170 180 190 200 210 220 100 110 120 130 140 pF1KE0 KPEQIQKWIRTRKLKYLGVPKYWGSGLH-DKNGKSYRFMIMDRFGSDLQKIYEANAKR-F :: :..:: . . :..: : :.: :: :::... .: .::. ... :. . CCDS77 KPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK----YRFLVLPSLGRSLQSALDVSPKHVL 230 240 250 260 270 150 160 170 180 190 200 pF1KE0 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGV :...:::.. :.:: ::..::.:::::.. : :.... .. .:: :. ::.:.:::: : CCDS77 SERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGK 280 290 300 310 320 330 210 220 230 240 250 260 pF1KE0 HKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPK : : : . :.: .:: :.: :.: .::::.::. :::::..:: : ::: . : . . CCDS77 HVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTE 340 350 360 370 380 390 270 280 290 300 310 320 pF1KE0 YVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLK . .: CCDS77 DIMKQKQKLPWDSF 400 410 >>CCDS11806.1 CSNK1D gene_id:1453|Hs108|chr17 (409 aa) initn: 331 init1: 188 opt: 427 Z-score: 361.9 bits: 75.8 E(32554): 7.7e-14 Smith-Waterman score: 471; 29.6% identity (59.3% similar) in 334 aa overlap (37-364:9-313) 10 20 30 40 50 60 pF1KE0 AQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSSESVGSD ...: ::.:.:: :::. :. ..: :. CCDS11 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIK 10 20 30 70 80 90 100 110 120 pF1KE0 APCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKY-WGSGLHDKNGK :: .:. : : :.:. ..: . :.: : .. : CCDS11 LECVKTKHPQ----LHIESKIYK------MMQGGV--------GIPTIRWCGAEGD---- 40 50 60 70 130 140 150 160 170 180 pF1KE0 SYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLL : :.:. .: .:. ... ...:: :::: :. .... .:::: ....: :.: .:.: CCDS11 -YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFL 80 90 100 110 120 130 190 200 210 220 230 240 pF1KE0 LNY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD .. :. . ::..:.::: .: .:.. .. :: ...::..: :. ::: : CCDS11 MGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD 140 150 160 170 180 190 250 260 270 280 290 300 pF1KE0 LEILGYCMIQWLTGHLPWED---NLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA :: ::: .. . : :::. : :: : :. .. : : : :. :.:.: CCDS11 LESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL---C---KGYPSEFA 200 210 220 230 240 310 320 330 340 350 360 pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK :.. . : . .:: : ::... . .. : . : .: .... :. .: ...... CCDS11 TYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERR 250 260 270 280 290 300 370 380 390 pF1KE0 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK . :: CCDS11 DREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKV 310 320 330 340 350 360 >>CCDS11805.1 CSNK1D gene_id:1453|Hs108|chr17 (415 aa) initn: 331 init1: 188 opt: 427 Z-score: 361.8 bits: 75.9 E(32554): 7.8e-14 Smith-Waterman score: 471; 29.6% identity (59.3% similar) in 334 aa overlap (37-364:9-313) 10 20 30 40 50 60 pF1KE0 AQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSSESVGSD ...: ::.:.:: :::. :. ..: :. CCDS11 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIK 10 20 30 70 80 90 100 110 120 pF1KE0 APCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKY-WGSGLHDKNGK :: .:. : : :.:. ..: . :.: : .. : CCDS11 LECVKTKHPQ----LHIESKIYK------MMQGGV--------GIPTIRWCGAEGD---- 40 50 60 70 130 140 150 160 170 180 pF1KE0 SYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLL : :.:. .: .:. ... ...:: :::: :. .... .:::: ....: :.: .:.: CCDS11 -YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFL 80 90 100 110 120 130 190 200 210 220 230 240 pF1KE0 LNY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD .. :. . ::..:.::: .: .:.. .. :: ...::..: :. ::: : CCDS11 MGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD 140 150 160 170 180 190 250 260 270 280 290 300 pF1KE0 LEILGYCMIQWLTGHLPWED---NLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA :: ::: .. . : :::. : :: : :. .. : : : :. :.:.: CCDS11 LESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL---C---KGYPSEFA 200 210 220 230 240 310 320 330 340 350 360 pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK :.. . : . .:: : ::... . .. : . : .: .... :. .: ...... CCDS11 TYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERR 250 260 270 280 290 300 370 380 390 pF1KE0 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK . :: CCDS11 DREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKV 310 320 330 340 350 360 >>CCDS13970.1 CSNK1E gene_id:1454|Hs108|chr22 (416 aa) initn: 339 init1: 188 opt: 419 Z-score: 355.4 bits: 74.7 E(32554): 1.8e-13 Smith-Waterman score: 476; 29.4% identity (59.1% similar) in 340 aa overlap (36-369:8-318) 10 20 30 40 50 60 pF1KE0 AAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYL-ADMNSSESVGS ....: ::.:.:: ::: :.. :.: :. CCDS13 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAI 10 20 30 70 80 90 100 110 120 pF1KE0 DAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKY-WGSGLHDKNG :: .:. : : :::. ..: . :.:. : .. : CCDS13 KLECVKTKHPQ----LHIESKFYK------MMQGGV--------GIPSIKWCGAEGD--- 40 50 60 70 130 140 150 160 170 180 pF1KE0 KSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL : :.:. .: .:. ... ...:: :::: :. .... .:::: ....: :.: .:. CCDS13 --YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNF 80 90 100 110 120 130 190 200 210 220 230 240 pF1KE0 LLNY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRG :.. :. . ::..:.::: .: .:.. .. :: ...::..: :. ::: CCDS13 LMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRD 140 150 160 170 180 190 250 260 270 280 290 pF1KE0 DLEILGYCMIQWLTGHLPWED---NLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEI ::: ::: .. . : :::. : :: : :. .. : : : :. :.:. CCDS13 DLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL---C---KGYPSEF 200 210 220 230 240 300 310 320 330 340 350 pF1KE0 AKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRK . :.. . : . .:: : ::... . .. : . : .: .... :. . . ... CCDS13 STYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRER 250 260 270 280 290 300 360 370 380 390 pF1KE0 KEIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK .: :. .. : CCDS13 REHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAGNTSPRAIS 310 320 330 340 350 360 396 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 17:56:47 2016 done: Wed Nov 2 17:56:47 2016 Total Scan time: 2.500 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]