FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0677, 263 aa 1>>>pF1KE0677 263 - 263 aa - 263 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3272+/-0.000276; mu= 7.7819+/- 0.017 mean_var=167.3163+/-33.773, 0's: 0 Z-trim(123.9): 272 B-trim: 159 in 2/59 Lambda= 0.099153 statistics sampled from 44258 (44587) to 44258 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.523), width: 16 Scan time: 8.620 The best scores are: opt bits E(85289) NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 1786 266.4 3.8e-71 XP_011538391 (OMIM: 606701) PREDICTED: dorsal root ( 298) 1268 192.3 8.5e-49 NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 422 71.4 2.9e-12 NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 403 68.8 2.4e-11 NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 360 62.5 1.2e-09 XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 356 61.8 1.3e-09 NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 356 61.9 1.7e-09 NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 348 60.7 3.4e-09 NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 352 61.5 3.5e-09 NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 352 61.5 3.5e-09 NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 352 61.5 3.5e-09 NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 348 60.7 3.6e-09 NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 343 60.1 7.2e-09 NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 335 58.7 9e-09 NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 335 58.8 1.1e-08 XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 332 58.3 1.3e-08 NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 336 59.1 1.3e-08 NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 332 58.4 1.5e-08 XP_006711451 (OMIM: 167420,202650) PREDICTED: pair ( 198) 330 58.0 1.6e-08 NP_008833 (OMIM: 167420,202650) paired mesoderm ho ( 217) 330 58.0 1.7e-08 NP_001297090 (OMIM: 106210,120430,136520,148190,16 ( 286) 332 58.4 1.7e-08 NP_001297089 (OMIM: 106210,120430,136520,148190,16 ( 286) 332 58.4 1.7e-08 NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245) 330 58.1 1.8e-08 NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 332 58.6 2.2e-08 NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 332 58.6 2.2e-08 NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 332 58.6 2.2e-08 NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 332 58.6 2.2e-08 NP_001245392 (OMIM: 106210,120430,136520,148190,16 ( 436) 332 58.6 2.3e-08 NP_001595 (OMIM: 106210,120430,136520,148190,16555 ( 436) 332 58.6 2.3e-08 NP_001297087 (OMIM: 106210,120430,136520,148190,16 ( 436) 332 58.6 2.3e-08 NP_001245391 (OMIM: 106210,120430,136520,148190,16 ( 436) 332 58.6 2.3e-08 NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 328 57.9 2.6e-08 NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 330 58.3 2.6e-08 NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 329 58.1 2.6e-08 NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 329 58.1 2.6e-08 NP_003021 (OMIM: 602504) short stature homeobox pr ( 355) 329 58.1 2.6e-08 NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 330 58.3 2.6e-08 NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 330 58.3 3e-08 NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 330 58.3 3e-08 NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 330 58.3 3e-08 NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 327 57.8 3e-08 NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 330 58.4 3.1e-08 NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299) 325 57.4 3.4e-08 NP_006875 (OMIM: 602504) short stature homeobox pr ( 331) 321 56.9 5.5e-08 XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 314 56.0 1.2e-07 NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 314 56.0 1.2e-07 XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 314 56.0 1.2e-07 NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 314 56.0 1.2e-07 NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 308 55.0 1.8e-07 NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 308 55.0 1.8e-07 >>NP_001263380 (OMIM: 606701) dorsal root ganglia homeob (263 aa) initn: 1786 init1: 1786 opt: 1786 Z-score: 1398.2 bits: 266.4 E(85289): 3.8e-71 Smith-Waterman score: 1786; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263) 10 20 30 40 50 60 pF1KE0 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTSSSPGPVAKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTSSSPGPVAKP 190 200 210 220 230 240 250 260 pF1KE0 APPDGSQEKTSPTKEQSEAEKSV ::::::::::::::::::::::: NP_001 APPDGSQEKTSPTKEQSEAEKSV 250 260 >>XP_011538391 (OMIM: 606701) PREDICTED: dorsal root gan (298 aa) initn: 1261 init1: 1261 opt: 1268 Z-score: 997.0 bits: 192.3 E(85289): 8.5e-49 Smith-Waterman score: 1683; 88.1% identity (88.1% similar) in 295 aa overlap (4-263:4-298) 10 20 30 40 50 60 pF1KE0 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDV 10 20 30 40 50 60 70 80 pF1KE0 FTREELAMKINLTEARVQ-----------------------------------VWFQNRR :::::::::::::::::: ::::::: XP_011 FTREELAMKINLTEARVQLANSCLKTELQIEINDTIIEHSEVEDHNFSLKGARVWFQNRR 70 80 90 100 110 120 90 100 110 120 130 140 pF1KE0 AKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGP 130 140 150 160 170 180 150 160 170 180 190 200 pF1KE0 AGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTAS 190 200 210 220 230 240 210 220 230 240 250 260 pF1KE0 VATLRMKAREHSEAVLQSANLLPSTSSSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VATLRMKAREHSEAVLQSANLLPSTSSSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV 250 260 270 280 290 >>NP_068745 (OMIM: 605420,609597,613451,615529) homeobox (411 aa) initn: 409 init1: 330 opt: 422 Z-score: 341.2 bits: 71.4 E(85289): 2.9e-12 Smith-Waterman score: 422; 42.2% identity (62.3% similar) in 199 aa overlap (32-220:213-407) 10 20 30 40 50 60 pF1KE0 FYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVF :.:::::::: ::: :: :: .::::::. NP_068 KEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVY 190 200 210 220 230 240 70 80 90 100 110 120 pF1KE0 TREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPP .::.:::. .::::::::::::::::::: :: .. :. .. : : .: : NP_068 AREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQ 250 260 270 280 290 300 130 140 150 160 170 pF1KE0 PGDQARSKKEALEAQQSLGRTVGPAGPFFPSCL------PGTLLNTAT----YAQALSHV . . ... : . . : : : :.:. ::. ...: . : ::: NP_068 IQNPSWLGNNG--AASPVPACVVPCDPV-PACMSPHAHPPGSGASSVTDFLSVSGAGSHV 310 320 330 340 350 180 190 200 210 220 230 pF1KE0 ASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTS .. . : : . .: ::. : . .:.:.:.:::::.::: :. NP_068 GQTHMGSLFGAASLSP-GLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT 360 370 380 390 400 410 240 250 260 pF1KE0 SSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV >>NP_620689 (OMIM: 300004,300215,300382,300419,308350,30 (562 aa) initn: 420 init1: 348 opt: 403 Z-score: 324.7 bits: 68.8 E(85289): 2.4e-11 Smith-Waterman score: 456; 40.9% identity (61.1% similar) in 247 aa overlap (20-232:314-557) 10 20 30 40 pF1KE0 MFYFHCPPQLEGTATFGNHSSG-DFDDGFLRRKQRRNRTTFTLQQLEAL :.: : ..:.:.::::: ::::: ::: : NP_620 TEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEEL 290 300 310 320 330 340 50 60 70 80 90 100 pF1KE0 EAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTER-GASDQEPGAKEP-- : .: .::::::::::::::...::::::::::::::::::: :. ::. . :: : NP_620 ERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGP 350 360 370 380 390 400 110 120 130 140 150 160 pF1KE0 MAEVTP-PPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFP--SCLP--GTLLN .. . : : . . :: : .. : : . . .. :. : : . :: :. :. NP_620 LSATHPLSPYLDASPFPPHHPALDS--AWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLG 410 420 430 440 450 460 170 180 190 pF1KE0 TATY--AQALSHVASLKGG---------PLCSCCV-------PDPM-------GLSFLPT .:. : .. : : .. . :: : . : : : :. NP_620 LSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPA 470 480 490 500 510 520 200 210 220 230 240 250 pF1KE0 YGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTSSSPGPVAKPAPPDGSQEKTSPTKE . . :..:.:.::.::.::. : : . :.::.::. NP_620 TAAADRRASSIAALRLKAKEHA-AQLTQLNILPGTSTGKEVC 530 540 550 560 260 pF1KE0 QSEAEKSV >>NP_006483 (OMIM: 136760,606014) homeobox protein arist (343 aa) initn: 382 init1: 329 opt: 360 Z-score: 294.3 bits: 62.5 E(85289): 1.2e-09 Smith-Waterman score: 385; 39.1% identity (65.0% similar) in 197 aa overlap (30-215:150-334) 10 20 30 40 50 pF1KE0 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPD . :.:::::::. ::: :: :: .::::: NP_006 NLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPD 120 130 140 150 160 170 60 70 80 90 100 110 pF1KE0 VFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINS :..::.::.. .::::::::::::::::::: :: .. :: ...:.. . .:. NP_006 VYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQE--GRNPFTAA-----YDISV 180 190 200 210 220 230 120 130 140 150 160 170 pF1KE0 PPPGDQARSKKEALEAQQSLGRTVGPAGPFF--PSCLPGTLLNTATYAQALSHVASLKGG : :. . ...: :. . : .:.:: . : .:. .. :.. . ::.. : NP_006 LPRTDSHPQLQNSLWASPGSG---SPGGPCLVSPEGIPSPCMS--PYSHPHGSVAGFMGV 240 250 260 270 280 180 190 200 210 220 pF1KE0 PLCSCCVPDPMGL-SFLPTYGCQS--------NRTASVATLRMKAREHSEAVLQSANLLP : : : ... .: :: : .: .. :...::.: .: NP_006 PAPSAAHPGIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT 290 300 310 320 330 340 230 240 250 260 pF1KE0 STSSSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV >>XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX home (231 aa) initn: 355 init1: 316 opt: 356 Z-score: 293.4 bits: 61.8 E(85289): 1.3e-09 Smith-Waterman score: 356; 38.2% identity (62.3% similar) in 212 aa overlap (22-220:25-227) 10 20 30 40 50 pF1KE0 MFYFHCPPQLEGTATFGNHSSGD-FDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTH :: :.. :.::.::::: ::: :: :: .:: XP_011 MDNCNSLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 YPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRN ::::..::.::.. .::::::::::::::::::: :: .. :. :: .: . . XP_011 YPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQ--AKSHFAA-----TYD 70 80 90 100 110 120 130 140 150 160 pF1KE0 INSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFP----SCL-PGTLL--NTATYAQALS :. : :. . .. : : .. : .: .. ..: ::. : . . ..:. . XP_011 ISVLPRTDSYPQIQNNLWAGNASGGSV-VTSCMLPRDTSSCMTPYSHSPRTDSSYTGFSN 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 HVASLKGGPLCSCCVPDPM-----GLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSA : ... :: . . . . : .: : :..:.:.:::::.::. . XP_011 HQNQFSHVPLNNFFTDSLLTGATNGHAF-ETKPEFERRSSSIAVLRMKAKEHTANISWAM 180 190 200 210 220 230 230 240 250 260 pF1KE0 NLLPSTSSSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV >>NP_008913 (OMIM: 601527,613456) ALX homeobox protein 1 (326 aa) initn: 355 init1: 316 opt: 356 Z-score: 291.5 bits: 61.9 E(85289): 1.7e-09 Smith-Waterman score: 356; 38.2% identity (62.3% similar) in 212 aa overlap (22-220:120-322) 10 20 30 40 50 pF1KE0 MFYFHCPPQLEGTATFGNHSSGD-FDDGFLRRKQRRNRTTFTLQQLEALEA :: :.. :.::.::::: ::: :: NP_008 TELNRAMDNCNSLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEK 90 100 110 120 130 140 60 70 80 90 100 110 pF1KE0 VFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVT :: .::::::..::.::.. .::::::::::::::::::: :: .. :. :: .: NP_008 VFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQ--AKSHFAA-- 150 160 170 180 190 200 120 130 140 150 160 pF1KE0 PPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFP----SCL-PGTLL--NTAT . .:. : :. . .. : : .. : .: .. ..: ::. : . . .. NP_008 ---TYDISVLPRTDSYPQIQNNLWAGNASGGSV-VTSCMLPRDTSSCMTPYSHSPRTDSS 210 220 230 240 250 260 170 180 190 200 210 pF1KE0 YAQALSHVASLKGGPLCSCCVPDPM-----GLSFLPTYGCQSNRTASVATLRMKAREHSE :. .: ... :: . . . . : .: : :..:.:.:::::.::. NP_008 YTGFSNHQNQFSHVPLNNFFTDSLLTGATNGHAF-ETKPEFERRSSSIAVLRMKAKEHTA 270 280 290 300 310 320 220 230 240 250 260 pF1KE0 AVLQSANLLPSTSSSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV . NP_008 NISWAM >>NP_005160 (OMIM: 602078,602753) paired mesoderm homeob (284 aa) initn: 402 init1: 343 opt: 348 Z-score: 286.1 bits: 60.7 E(85289): 3.4e-09 Smith-Waterman score: 363; 49.0% identity (61.9% similar) in 147 aa overlap (30-158:87-231) 10 20 30 40 50 pF1KE0 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPD .::::: ::::: ::. :: :::.::::: NP_005 CALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPD 60 70 80 90 100 110 60 70 80 90 100 110 pF1KE0 VFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQ----EPGAKEPMAEVT----- ..::::::.::.::::::::::::::::.:: ::.:: . :::. :. . NP_005 IYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDD 120 130 140 150 160 170 120 130 140 150 160 pF1KE0 -------PPPVRNINSPPPGDQ--ARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNT : : . . ::: : . .:: :: :: :. : :.: NP_005 SKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGP-GPG-PQPLKGALWAG 180 190 200 210 220 230 170 180 190 200 210 220 pF1KE0 ATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVL NP_005 VAGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF 240 250 260 270 280 >>NP_001128726 (OMIM: 167410,268220) paired box protein (505 aa) initn: 396 init1: 318 opt: 352 Z-score: 285.9 bits: 61.5 E(85289): 3.5e-09 Smith-Waterman score: 352; 45.8% identity (67.6% similar) in 142 aa overlap (29-169:213-350) 10 20 30 40 50 pF1KE0 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYP :.:::::.::::: .::: :: .: .:::: NP_001 KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 190 200 210 220 230 240 60 70 80 90 100 110 pF1KE0 DVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNIN :..::::::.. .::::::::::.::::.::: . :: .: . .. . :: .. NP_001 DIYTREELAQRTKLTEARVQVWFSNRRARWRK-QAGA-NQLAAFNHLLPGGFPPT--GMP 250 260 270 280 290 120 130 140 150 160 170 pF1KE0 SPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCL-PGTLLNTATYAQALSHVASLKGG . :: . : . .:. : :: :. :: . : : .:. :.. : NP_001 TLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSF 300 310 320 330 340 350 180 190 200 210 220 230 pF1KE0 PLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTSSSPGPV NP_001 SSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATS 360 370 380 390 400 410 >>NP_039236 (OMIM: 167410,268220) paired box protein Pax (518 aa) initn: 374 init1: 318 opt: 352 Z-score: 285.8 bits: 61.5 E(85289): 3.5e-09 Smith-Waterman score: 352; 45.8% identity (67.6% similar) in 142 aa overlap (29-169:211-348) 10 20 30 40 50 pF1KE0 MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYP :.:::::.::::: .::: :: .: .:::: NP_039 KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 190 200 210 220 230 240 60 70 80 90 100 110 pF1KE0 DVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNIN :..::::::.. .::::::::::.::::.::: . :: .: . .. . :: .. NP_039 DIYTREELAQRTKLTEARVQVWFSNRRARWRK-QAGA-NQLAAFNHLLPGGFPPT--GMP 250 260 270 280 290 120 130 140 150 160 170 pF1KE0 SPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCL-PGTLLNTATYAQALSHVASLKGG . :: . : . .:. : :: :. :: . : : .:. :.. : NP_039 TLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSF 300 310 320 330 340 350 180 190 200 210 220 230 pF1KE0 PLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTSSSPGPV NP_039 SSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATS 360 370 380 390 400 410 263 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:17:00 2016 done: Sat Nov 5 04:17:01 2016 Total Scan time: 8.620 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]