FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0681, 270 aa 1>>>pF1KE0681 270 - 270 aa - 270 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3192+/-0.00105; mu= 6.3812+/- 0.062 mean_var=198.6541+/-42.209, 0's: 0 Z-trim(108.9): 133 B-trim: 0 in 0/52 Lambda= 0.090997 statistics sampled from 10392 (10538) to 10392 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.324), width: 16 Scan time: 1.900 The best scores are: opt bits E(32554) CCDS7133.1 NEBL gene_id:10529|Hs108|chr10 ( 270) 1874 258.4 3.8e-69 CCDS11331.1 LASP1 gene_id:3927|Hs108|chr17 ( 261) 1102 157.1 1.2e-38 CCDS7134.1 NEBL gene_id:10529|Hs108|chr10 (1014) 654 98.9 1.5e-20 CCDS62164.1 LASP1 gene_id:3927|Hs108|chr17 ( 205) 572 87.4 9.1e-18 >>CCDS7133.1 NEBL gene_id:10529|Hs108|chr10 (270 aa) initn: 1874 init1: 1874 opt: 1874 Z-score: 1354.8 bits: 258.4 E(32554): 3.8e-69 Smith-Waterman score: 1874; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270) 10 20 30 40 50 60 pF1KE0 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 190 200 210 220 230 240 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: CCDS71 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 250 260 270 >>CCDS11331.1 LASP1 gene_id:3927|Hs108|chr17 (261 aa) initn: 1153 init1: 813 opt: 1102 Z-score: 807.2 bits: 157.1 E(32554): 1.2e-38 Smith-Waterman score: 1130; 63.6% identity (82.7% similar) in 272 aa overlap (1-269:1-261) 10 20 30 40 50 60 pF1KE0 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ :::.::::::.::::::::::::.:::.:::::.:::.:::.:::::::::::::::::: CCDS11 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV ::: ::::::::::::::::::::.::..::..::.:::.:.:::::::.:.::.::::. CCDS11 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV-APV ::::.:::.. . : . . : :...: . ..:. .: .:... : . ::: CCDS11 KYHEEFEKSR---MGPSGGEGM-EPERRDSQ--DGSSYR--RP--LEQQQPHHIPTSAPV 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LPGAYQQSHSQGYGYMHQTS--VSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYI :: .:.:: ... . :: .:: . . : :::.::::: :::::::.::: : CCDS11 YQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTI 180 190 200 210 220 240 250 260 270 pF1KE0 VNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::: ::::::::::.::: ::::::::.: . CCDS11 VNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 230 240 250 260 >>CCDS7134.1 NEBL gene_id:10529|Hs108|chr10 (1014 aa) initn: 863 init1: 654 opt: 654 Z-score: 482.3 bits: 98.9 E(32554): 1.5e-20 Smith-Waterman score: 999; 59.3% identity (66.7% similar) in 300 aa overlap (54-270:716-1014) 30 40 50 60 70 80 pF1KE0 YWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ--SFTTVADTPENLRLKQQSELQ :..: : ::.. ::: :.:...: CCDS71 VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENI 690 700 710 720 730 740 90 100 110 120 130 140 pF1KE0 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP :.::: .: .. ::: :.. ::: ....:..:..:: :::::::::::::::::::::: CCDS71 SSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDP 750 760 770 780 790 800 150 160 170 pF1KE0 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV------------------------- ::::::::::::::::::::::::::::::::::: CCDS71 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSR 810 820 830 840 850 860 180 pF1KE0 --------------------------------------------------------APVL :::: CCDS71 SLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVL 870 880 890 900 910 920 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 930 940 950 960 970 980 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: CCDS71 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 990 1000 1010 >>CCDS62164.1 LASP1 gene_id:3927|Hs108|chr17 (205 aa) initn: 590 init1: 321 opt: 572 Z-score: 432.5 bits: 87.4 E(32554): 9.1e-18 Smith-Waterman score: 573; 50.8% identity (75.9% similar) in 199 aa overlap (74-269:19-205) 50 60 70 80 90 100 pF1KE0 YKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTD :.... :: .:.::..::..::.:::.:.: CCDS62 MLPLRDLQDDTEHEELQGLREEALLQ-RVRYKEEFEKNKGKGFSVVAD 10 20 30 40 110 120 130 140 150 160 pF1KE0 TPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHP ::::::.:.::.::::.::::.:::.. . : . . : :...: . ..:. .: CCDS62 TPELQRIKKTQDQISNIKYHEEFEKSR---MGPSGGEGM-EPERRDSQ--DGSSYR--RP 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 HIVEMDRRPGIIV-APVLPGAYQQSHSQGYGYMHQTS--VSSMRSMQHSPNLRTYRAMYD .:... : . ::: :: .:.:: ... . :: .:: . . : :::.:: CCDS62 --LEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR-YRAVYD 100 110 120 130 140 150 230 240 250 260 270 pF1KE0 YSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN ::: :::::::.::: ::::: ::::::::::.::: ::::::::.: . CCDS62 YSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 160 170 180 190 200 270 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:18:01 2016 done: Sat Nov 5 04:18:01 2016 Total Scan time: 1.900 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]