FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0681, 270 aa 1>>>pF1KE0681 270 - 270 aa - 270 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6975+/-0.000491; mu= 11.0828+/- 0.030 mean_var=337.7530+/-79.176, 0's: 0 Z-trim(116.0): 176 B-trim: 1242 in 1/56 Lambda= 0.069787 statistics sampled from 26547 (26793) to 26547 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.314), width: 16 Scan time: 5.500 The best scores are: opt bits E(85289) NP_998734 (OMIM: 605491) nebulette isoform 2 [Homo ( 270) 1874 202.4 7.1e-52 NP_001166955 (OMIM: 605491) nebulette isoform 3 [H ( 224) 1473 161.9 9.3e-40 XP_005252400 (OMIM: 605491) PREDICTED: nebulette i ( 933) 1175 133.0 1.9e-30 NP_006139 (OMIM: 602920) LIM and SH3 domain protei ( 261) 1102 124.7 1.8e-28 XP_005252399 (OMIM: 605491) PREDICTED: nebulette i ( 980) 654 80.6 1.2e-14 XP_016870957 (OMIM: 605491) PREDICTED: nebulette i ( 998) 654 80.6 1.2e-14 XP_016870956 (OMIM: 605491) PREDICTED: nebulette i ( 998) 654 80.6 1.2e-14 XP_011517593 (OMIM: 605491) PREDICTED: nebulette i ( 998) 654 80.6 1.2e-14 NP_006384 (OMIM: 605491) nebulette isoform 1 [Homo (1014) 654 80.6 1.2e-14 NP_001258537 (OMIM: 602920) LIM and SH3 domain pro ( 205) 572 71.1 1.8e-12 XP_005252401 (OMIM: 605491) PREDICTED: nebulette i ( 880) 535 68.5 4.7e-11 XP_005269924 (OMIM: 602873) PREDICTED: nebulin-rel (1627) 387 54.1 1.9e-06 NP_001309874 (OMIM: 602873) nebulin-related-anchor (1694) 387 54.1 2e-06 XP_011538134 (OMIM: 602873) PREDICTED: nebulin-rel (1695) 387 54.1 2e-06 NP_006166 (OMIM: 602873) nebulin-related-anchoring (1695) 387 54.1 2e-06 XP_005269922 (OMIM: 602873) PREDICTED: nebulin-rel (1695) 387 54.1 2e-06 XP_006717933 (OMIM: 602873) PREDICTED: nebulin-rel (1696) 387 54.1 2e-06 XP_005269921 (OMIM: 602873) PREDICTED: nebulin-rel (1696) 387 54.1 2e-06 NP_932326 (OMIM: 602873) nebulin-related-anchoring (1730) 387 54.2 2e-06 NP_001248392 (OMIM: 602873) nebulin-related-anchor (1731) 387 54.2 2e-06 NP_004534 (OMIM: 161650,256030) nebulin isoform 3 (6669) 333 49.8 0.00016 XP_011509529 (OMIM: 161650,256030) PREDICTED: nebu (7067) 333 49.8 0.00017 XP_005246674 (OMIM: 161650,256030) PREDICTED: nebu (7553) 333 49.9 0.00017 XP_011509528 (OMIM: 161650,256030) PREDICTED: nebu (7796) 333 49.9 0.00017 XP_016859674 (OMIM: 161650,256030) PREDICTED: nebu (8184) 333 49.9 0.00018 XP_016859673 (OMIM: 161650,256030) PREDICTED: nebu (8277) 333 49.9 0.00018 XP_005246672 (OMIM: 161650,256030) PREDICTED: nebu (8277) 333 49.9 0.00018 XP_016859672 (OMIM: 161650,256030) PREDICTED: nebu (8277) 333 49.9 0.00018 XP_011509527 (OMIM: 161650,256030) PREDICTED: nebu (8277) 333 49.9 0.00018 XP_005246669 (OMIM: 161650,256030) PREDICTED: nebu (8282) 333 49.9 0.00018 XP_005246670 (OMIM: 161650,256030) PREDICTED: nebu (8282) 333 49.9 0.00018 XP_005246667 (OMIM: 161650,256030) PREDICTED: nebu (8308) 333 49.9 0.00018 XP_005246668 (OMIM: 161650,256030) PREDICTED: nebu (8308) 333 49.9 0.00018 XP_016859671 (OMIM: 161650,256030) PREDICTED: nebu (8308) 333 49.9 0.00018 XP_005246665 (OMIM: 161650,256030) PREDICTED: nebu (8339) 333 49.9 0.00018 XP_016859670 (OMIM: 161650,256030) PREDICTED: nebu (8339) 333 49.9 0.00018 XP_005246663 (OMIM: 161650,256030) PREDICTED: nebu (8370) 333 49.9 0.00018 XP_005246660 (OMIM: 161650,256030) PREDICTED: nebu (8370) 333 49.9 0.00018 XP_005246661 (OMIM: 161650,256030) PREDICTED: nebu (8370) 333 49.9 0.00018 XP_016859668 (OMIM: 161650,256030) PREDICTED: nebu (8370) 333 49.9 0.00018 XP_006712604 (OMIM: 161650,256030) PREDICTED: nebu (8370) 333 49.9 0.00018 XP_016859669 (OMIM: 161650,256030) PREDICTED: nebu (8370) 333 49.9 0.00018 XP_006712605 (OMIM: 161650,256030) PREDICTED: nebu (8370) 333 49.9 0.00018 XP_005246658 (OMIM: 161650,256030) PREDICTED: nebu (8401) 333 49.9 0.00018 XP_005246659 (OMIM: 161650,256030) PREDICTED: nebu (8401) 333 49.9 0.00018 XP_005246656 (OMIM: 161650,256030) PREDICTED: nebu (8432) 333 49.9 0.00018 XP_005246657 (OMIM: 161650,256030) PREDICTED: nebu (8432) 333 49.9 0.00018 XP_005246655 (OMIM: 161650,256030) PREDICTED: nebu (8463) 333 49.9 0.00018 XP_016859667 (OMIM: 161650,256030) PREDICTED: nebu (8463) 333 49.9 0.00018 XP_005246653 (OMIM: 161650,256030) PREDICTED: nebu (8463) 333 49.9 0.00018 >>NP_998734 (OMIM: 605491) nebulette isoform 2 [Homo sap (270 aa) initn: 1874 init1: 1874 opt: 1874 Z-score: 1052.3 bits: 202.4 E(85289): 7.1e-52 Smith-Waterman score: 1874; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270) 10 20 30 40 50 60 pF1KE0 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 190 200 210 220 230 240 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: NP_998 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 250 260 270 >>NP_001166955 (OMIM: 605491) nebulette isoform 3 [Homo (224 aa) initn: 1473 init1: 1473 opt: 1473 Z-score: 834.8 bits: 161.9 E(85289): 9.3e-40 Smith-Waterman score: 1473; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KE0 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::: NP_001 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLDLPSHVRLQCPG 190 200 210 220 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN >>XP_005252400 (OMIM: 605491) PREDICTED: nebulette isofo (933 aa) initn: 1092 init1: 1092 opt: 1175 Z-score: 667.4 bits: 133.0 E(85289): 1.9e-30 Smith-Waterman score: 1175; 79.9% identity (90.2% similar) in 224 aa overlap (49-270:711-933) 20 30 40 50 60 70 pF1KE0 NCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ--SFTTVADTPENLRLKQ .: :..: : ::.. ::: :.:. XP_005 EQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKK 690 700 710 720 730 740 80 90 100 110 120 130 pF1KE0 QSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTP ..: :.::: .: .. ::: :.. ::: ....:..:..:: ::::::::::::::::: XP_005 NQENISSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTP 750 760 770 780 790 140 150 160 170 180 190 pF1KE0 VVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHSQGYGYMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHSQGYGYMH 800 810 820 830 840 850 200 210 220 230 240 250 pF1KE0 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 860 870 880 890 900 910 260 270 pF1KE0 RTGMLPANYIEFVN :::::::::::::: XP_005 RTGMLPANYIEFVN 920 930 >>NP_006139 (OMIM: 602920) LIM and SH3 domain protein 1 (261 aa) initn: 1153 init1: 813 opt: 1102 Z-score: 632.3 bits: 124.7 E(85289): 1.8e-28 Smith-Waterman score: 1130; 63.6% identity (82.7% similar) in 272 aa overlap (1-269:1-261) 10 20 30 40 50 60 pF1KE0 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ :::.::::::.::::::::::::.:::.:::::.:::.:::.:::::::::::::::::: NP_006 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV ::: ::::::::::::::::::::.::..::..::.:::.:.:::::::.:.::.::::. NP_006 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV-APV ::::.:::.. . : . . : :...: . ..:. .: .:... : . ::: NP_006 KYHEEFEKSR---MGPSGGEGM-EPERRDSQ--DGSSYR--RP--LEQQQPHHIPTSAPV 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LPGAYQQSHSQGYGYMHQTS--VSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYI :: .:.:: ... . :: .:: . . : :::.::::: :::::::.::: : NP_006 YQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTI 180 190 200 210 220 240 250 260 270 pF1KE0 VNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::: ::::::::::.::: ::::::::.: . NP_006 VNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 230 240 250 260 >>XP_005252399 (OMIM: 605491) PREDICTED: nebulette isofo (980 aa) initn: 863 init1: 654 opt: 654 Z-score: 383.8 bits: 80.6 E(85289): 1.2e-14 Smith-Waterman score: 999; 59.3% identity (66.7% similar) in 300 aa overlap (54-270:682-980) 30 40 50 60 70 80 pF1KE0 YWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ--SFTTVADTPENLRLKQQSELQ :..: : ::.. ::: :.:...: XP_005 VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENI 660 670 680 690 700 710 90 100 110 120 130 140 pF1KE0 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP :.::: .: .. ::: :.. ::: ....:..:..:: :::::::::::::::::::::: XP_005 SSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDP 720 730 740 750 760 770 150 160 170 pF1KE0 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV------------------------- ::::::::::::::::::::::::::::::::::: XP_005 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSR 780 790 800 810 820 830 180 pF1KE0 --------------------------------------------------------APVL :::: XP_005 SLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVL 840 850 860 870 880 890 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 900 910 920 930 940 950 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: XP_005 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 960 970 980 >>XP_016870957 (OMIM: 605491) PREDICTED: nebulette isofo (998 aa) initn: 863 init1: 654 opt: 654 Z-score: 383.7 bits: 80.6 E(85289): 1.2e-14 Smith-Waterman score: 999; 59.3% identity (66.7% similar) in 300 aa overlap (54-270:700-998) 30 40 50 60 70 80 pF1KE0 YWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ--SFTTVADTPENLRLKQQSELQ :..: : ::.. ::: :.:...: XP_016 VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENI 670 680 690 700 710 720 90 100 110 120 130 140 pF1KE0 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP :.::: .: .. ::: :.. ::: ....:..:..:: :::::::::::::::::::::: XP_016 SSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDP 730 740 750 760 770 780 150 160 170 pF1KE0 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV------------------------- ::::::::::::::::::::::::::::::::::: XP_016 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSR 790 800 810 820 830 840 180 pF1KE0 --------------------------------------------------------APVL :::: XP_016 SLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVL 850 860 870 880 890 900 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 910 920 930 940 950 960 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: XP_016 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 970 980 990 >>XP_016870956 (OMIM: 605491) PREDICTED: nebulette isofo (998 aa) initn: 863 init1: 654 opt: 654 Z-score: 383.7 bits: 80.6 E(85289): 1.2e-14 Smith-Waterman score: 999; 59.3% identity (66.7% similar) in 300 aa overlap (54-270:700-998) 30 40 50 60 70 80 pF1KE0 YWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ--SFTTVADTPENLRLKQQSELQ :..: : ::.. ::: :.:...: XP_016 VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENI 670 680 690 700 710 720 90 100 110 120 130 140 pF1KE0 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP :.::: .: .. ::: :.. ::: ....:..:..:: :::::::::::::::::::::: XP_016 SSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDP 730 740 750 760 770 780 150 160 170 pF1KE0 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV------------------------- ::::::::::::::::::::::::::::::::::: XP_016 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSR 790 800 810 820 830 840 180 pF1KE0 --------------------------------------------------------APVL :::: XP_016 SLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVL 850 860 870 880 890 900 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 910 920 930 940 950 960 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: XP_016 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 970 980 990 >>XP_011517593 (OMIM: 605491) PREDICTED: nebulette isofo (998 aa) initn: 863 init1: 654 opt: 654 Z-score: 383.7 bits: 80.6 E(85289): 1.2e-14 Smith-Waterman score: 999; 59.3% identity (66.7% similar) in 300 aa overlap (54-270:700-998) 30 40 50 60 70 80 pF1KE0 YWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ--SFTTVADTPENLRLKQQSELQ :..: : ::.. ::: :.:...: XP_011 VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENI 670 680 690 700 710 720 90 100 110 120 130 140 pF1KE0 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP :.::: .: .. ::: :.. ::: ....:..:..:: :::::::::::::::::::::: XP_011 SSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDP 730 740 750 760 770 780 150 160 170 pF1KE0 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV------------------------- ::::::::::::::::::::::::::::::::::: XP_011 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSR 790 800 810 820 830 840 180 pF1KE0 --------------------------------------------------------APVL :::: XP_011 SLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVL 850 860 870 880 890 900 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 910 920 930 940 950 960 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: XP_011 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 970 980 990 >>NP_006384 (OMIM: 605491) nebulette isoform 1 [Homo sap (1014 aa) initn: 863 init1: 654 opt: 654 Z-score: 383.6 bits: 80.6 E(85289): 1.2e-14 Smith-Waterman score: 999; 59.3% identity (66.7% similar) in 300 aa overlap (54-270:716-1014) 30 40 50 60 70 80 pF1KE0 YWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ--SFTTVADTPENLRLKQQSELQ :..: : ::.. ::: :.:...: NP_006 VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENI 690 700 710 720 730 740 90 100 110 120 130 140 pF1KE0 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP :.::: .: .. ::: :.. ::: ....:..:..:: :::::::::::::::::::::: NP_006 SSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDP 750 760 770 780 790 800 150 160 170 pF1KE0 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV------------------------- ::::::::::::::::::::::::::::::::::: NP_006 VTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSR 810 820 830 840 850 860 180 pF1KE0 --------------------------------------------------------APVL :::: NP_006 SLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVL 870 880 890 900 910 920 190 200 210 220 230 240 pF1KE0 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 930 940 950 960 970 980 250 260 270 pF1KE0 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN :::::::::::::::::::::::::::::: NP_006 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 990 1000 1010 >>NP_001258537 (OMIM: 602920) LIM and SH3 domain protein (205 aa) initn: 590 init1: 321 opt: 572 Z-score: 344.8 bits: 71.1 E(85289): 1.8e-12 Smith-Waterman score: 573; 50.8% identity (75.9% similar) in 199 aa overlap (74-269:19-205) 50 60 70 80 90 100 pF1KE0 YKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTD :.... :: .:.::..::..::.:::.:.: NP_001 MLPLRDLQDDTEHEELQGLREEALLQ-RVRYKEEFEKNKGKGFSVVAD 10 20 30 40 110 120 130 140 150 160 pF1KE0 TPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHP ::::::.:.::.::::.::::.:::.. . : . . : :...: . ..:. .: NP_001 TPELQRIKKTQDQISNIKYHEEFEKSR---MGPSGGEGM-EPERRDSQ--DGSSYR--RP 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 HIVEMDRRPGIIV-APVLPGAYQQSHSQGYGYMHQTS--VSSMRSMQHSPNLRTYRAMYD .:... : . ::: :: .:.:: ... . :: .:: . . : :::.:: NP_001 --LEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR-YRAVYD 100 110 120 130 140 150 230 240 250 260 270 pF1KE0 YSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN ::: :::::::.::: ::::: ::::::::::.::: ::::::::.: . NP_001 YSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 160 170 180 190 200 270 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:18:02 2016 done: Sat Nov 5 04:18:03 2016 Total Scan time: 5.500 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]