FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0689, 280 aa 1>>>pF1KE0689 280 - 280 aa - 280 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6031+/-0.00112; mu= 7.7260+/- 0.066 mean_var=110.5941+/-23.071, 0's: 0 Z-trim(105.7): 171 B-trim: 0 in 0/51 Lambda= 0.121957 statistics sampled from 8370 (8589) to 8370 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.264), width: 16 Scan time: 2.280 The best scores are: opt bits E(32554) CCDS47112.1 DAPP1 gene_id:27071|Hs108|chr4 ( 280) 1895 344.5 4.9e-95 CCDS77945.1 DAPP1 gene_id:27071|Hs108|chr4 ( 263) 1756 320.1 1.1e-87 CCDS47243.1 RASA1 gene_id:5921|Hs108|chr5 ( 870) 312 66.3 8.6e-11 CCDS34200.1 RASA1 gene_id:5921|Hs108|chr5 (1047) 312 66.4 1e-10 >>CCDS47112.1 DAPP1 gene_id:27071|Hs108|chr4 (280 aa) initn: 1895 init1: 1895 opt: 1895 Z-score: 1819.6 bits: 344.5 E(32554): 4.9e-95 Smith-Waterman score: 1895; 100.0% identity (100.0% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK :::::::::::::::::::::::::::::::::::::::: CCDS47 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK 250 260 270 280 >>CCDS77945.1 DAPP1 gene_id:27071|Hs108|chr4 (263 aa) initn: 1756 init1: 1756 opt: 1756 Z-score: 1687.8 bits: 320.1 E(32554): 1.1e-87 Smith-Waterman score: 1756; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK :::::::::::::::::: CCDS77 AKTGVEADEWIKILRWKLVKDKS 250 260 >>CCDS47243.1 RASA1 gene_id:5921|Hs108|chr5 (870 aa) initn: 250 init1: 135 opt: 312 Z-score: 307.2 bits: 66.3 E(32554): 8.6e-11 Smith-Waterman score: 312; 28.7% identity (61.0% similar) in 254 aa overlap (35-275:174-414) 10 20 30 40 50 60 pF1KE0 ELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSN :.::..... : ::.. : :.:.: :. CCDS47 TNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSD 150 160 170 180 190 200 70 80 90 100 110 120 pF1KE0 ETTGLYSLSVRAKDSVKHFHVEYT-GYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLM .: : ::: :.......:.. : . .: .: ..:. :.. :. .. .. . . CCDS47 NTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEG-----Y 210 220 230 240 250 130 140 150 160 170 180 pF1KE0 VLKHPYPRKVEEPSIYESVRVHTAMQTGR--TEDDLVPTAPSLGTKEGYLTKQG-GLVKT ::.: : . .: . ..: . ..: : :.: . . .:.::: :.: : : CCDS47 YLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNI----VKKGYLLKKGKG--KR 260 270 280 290 300 310 190 200 210 220 230 pF1KE0 WKTRWFTLHRNE--LKYFK-DQMSPEPIRILDLTECSA-VQFDYSQERVNCFCLVFPFRT ::. .: :. .. : ::. .. . .: ..::. ::. : : : ::: .: . CCDS47 WKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFS 320 330 340 350 360 370 240 250 260 270 280 pF1KE0 -----FYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK ::. ..: .:..:.: :. . ..::. . : .. : : CCDS47 EEHYIFYFAGETPEQAEDWMKGLQ-AFCNLRKS-SPGTSNKRLRQVSSLVLHIEEAHKLP 380 390 400 410 420 430 CCDS47 VKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKD 440 450 460 470 480 490 >>CCDS34200.1 RASA1 gene_id:5921|Hs108|chr5 (1047 aa) initn: 242 init1: 135 opt: 312 Z-score: 306.1 bits: 66.4 E(32554): 1e-10 Smith-Waterman score: 312; 28.7% identity (61.0% similar) in 254 aa overlap (35-275:351-591) 10 20 30 40 50 60 pF1KE0 ELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSN :.::..... : ::.. : :.:.: :. CCDS34 TNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSD 330 340 350 360 370 380 70 80 90 100 110 120 pF1KE0 ETTGLYSLSVRAKDSVKHFHVEYT-GYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLM .: : ::: :.......:.. : . .: .: ..:. :.. :. .. .. . . CCDS34 NTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEG-----Y 390 400 410 420 430 130 140 150 160 170 180 pF1KE0 VLKHPYPRKVEEPSIYESVRVHTAMQTGR--TEDDLVPTAPSLGTKEGYLTKQG-GLVKT ::.: : . .: . ..: . ..: : :.: . . .:.::: :.: : : CCDS34 YLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNI----VKKGYLLKKGKG--KR 440 450 460 470 480 190 200 210 220 230 pF1KE0 WKTRWFTLHRNE--LKYFK-DQMSPEPIRILDLTECSA-VQFDYSQERVNCFCLVFPFRT ::. .: :. .. : ::. .. . .: ..::. ::. : : : ::: .: . CCDS34 WKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFS 490 500 510 520 530 540 240 250 260 270 280 pF1KE0 -----FYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK ::. ..: .:..:.: :. . ..::. . : .. : : CCDS34 EEHYIFYFAGETPEQAEDWMKGLQ-AFCNLRKS-SPGTSNKRLRQVSSLVLHIEEAHKLP 550 560 570 580 590 600 CCDS34 VKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKD 610 620 630 640 650 660 280 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:47:16 2016 done: Sat Nov 5 02:47:16 2016 Total Scan time: 2.280 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]