FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0689, 280 aa 1>>>pF1KE0689 280 - 280 aa - 280 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9039+/-0.000531; mu= 6.7250+/- 0.032 mean_var=207.5048+/-46.648, 0's: 0 Z-trim(113.2): 286 B-trim: 773 in 1/49 Lambda= 0.089035 statistics sampled from 22081 (22505) to 22081 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.264), width: 16 Scan time: 7.070 The best scores are: opt bits E(85289) NP_055210 (OMIM: 605768) dual adapter for phosphot ( 280) 1895 256.6 3.9e-68 XP_011530142 (OMIM: 605768) PREDICTED: dual adapte ( 267) 1758 238.9 7.5e-63 NP_001293080 (OMIM: 605768) dual adapter for phosp ( 263) 1756 238.7 8.9e-63 XP_016863512 (OMIM: 605768) PREDICTED: dual adapte ( 258) 1557 213.1 4.4e-55 XP_016863513 (OMIM: 605768) PREDICTED: dual adapte ( 258) 1557 213.1 4.4e-55 XP_011530144 (OMIM: 605768) PREDICTED: dual adapte ( 258) 1557 213.1 4.4e-55 XP_011530145 (OMIM: 605768) PREDICTED: dual adapte ( 158) 1081 151.7 8.2e-37 NP_072179 (OMIM: 139150,605462,608354,608355) ras ( 870) 312 53.9 1.3e-06 XP_011541827 (OMIM: 139150,605462,608354,608355) P (1018) 312 53.9 1.4e-06 NP_002881 (OMIM: 139150,605462,608354,608355) ras (1047) 312 54.0 1.4e-06 XP_011541829 (OMIM: 139150,605462,608354,608355) P ( 539) 257 46.5 0.00013 NP_001177725 (OMIM: 600508) cytoplasmic protein NC ( 313) 231 42.9 0.00092 NP_006144 (OMIM: 600508) cytoplasmic protein NCK1 ( 377) 231 43.0 0.001 NP_001278928 (OMIM: 600508) cytoplasmic protein NC ( 377) 231 43.0 0.001 XP_016860592 (OMIM: 604930) PREDICTED: cytoplasmic ( 380) 224 42.1 0.0019 NP_003572 (OMIM: 604930) cytoplasmic protein NCK2 ( 380) 224 42.1 0.0019 XP_016860593 (OMIM: 604930) PREDICTED: cytoplasmic ( 380) 224 42.1 0.0019 XP_011510293 (OMIM: 604930) PREDICTED: cytoplasmic ( 380) 224 42.1 0.0019 NP_001004720 (OMIM: 604930) cytoplasmic protein NC ( 380) 224 42.1 0.0019 XP_006712860 (OMIM: 604930) PREDICTED: cytoplasmic ( 380) 224 42.1 0.0019 XP_016860594 (OMIM: 604930) PREDICTED: cytoplasmic ( 380) 224 42.1 0.0019 XP_016871979 (OMIM: 603075,607772) PREDICTED: plec ( 334) 220 41.5 0.0025 NP_001182537 (OMIM: 603075,607772) pleckstrin homo ( 334) 220 41.5 0.0025 XP_016871980 (OMIM: 603075,607772) PREDICTED: plec ( 334) 220 41.5 0.0025 XP_005270078 (OMIM: 603075,607772) PREDICTED: plec ( 334) 220 41.5 0.0025 XP_016871978 (OMIM: 603075,607772) PREDICTED: plec ( 366) 220 41.6 0.0027 XP_016871975 (OMIM: 603075,607772) PREDICTED: plec ( 383) 220 41.6 0.0028 NP_001317107 (OMIM: 603075,607772) pleckstrin homo ( 383) 220 41.6 0.0028 XP_016871977 (OMIM: 603075,607772) PREDICTED: plec ( 383) 220 41.6 0.0028 XP_016871976 (OMIM: 603075,607772) PREDICTED: plec ( 383) 220 41.6 0.0028 XP_005270076 (OMIM: 603075,607772) PREDICTED: plec ( 393) 220 41.6 0.0028 XP_016871972 (OMIM: 603075,607772) PREDICTED: plec ( 393) 220 41.6 0.0028 XP_016871974 (OMIM: 603075,607772) PREDICTED: plec ( 393) 220 41.6 0.0028 XP_016871973 (OMIM: 603075,607772) PREDICTED: plec ( 393) 220 41.6 0.0028 XP_016871969 (OMIM: 603075,607772) PREDICTED: plec ( 404) 220 41.6 0.0029 XP_005270073 (OMIM: 603075,607772) PREDICTED: plec ( 404) 220 41.6 0.0029 NP_001001974 (OMIM: 603075,607772) pleckstrin homo ( 404) 220 41.6 0.0029 XP_016871970 (OMIM: 603075,607772) PREDICTED: plec ( 404) 220 41.6 0.0029 NP_067635 (OMIM: 603075,607772) pleckstrin homolog ( 404) 220 41.6 0.0029 XP_016871971 (OMIM: 603075,607772) PREDICTED: plec ( 404) 220 41.6 0.0029 XP_016871968 (OMIM: 603075,607772) PREDICTED: plec ( 406) 220 41.6 0.0029 XP_011538326 (OMIM: 603075,607772) PREDICTED: plec ( 416) 220 41.6 0.0029 XP_011538323 (OMIM: 603075,607772) PREDICTED: plec ( 416) 220 41.6 0.0029 XP_011538324 (OMIM: 603075,607772) PREDICTED: plec ( 416) 220 41.6 0.0029 XP_011538321 (OMIM: 603075,607772) PREDICTED: plec ( 416) 220 41.6 0.0029 XP_011538320 (OMIM: 603075,607772) PREDICTED: plec ( 416) 220 41.6 0.0029 XP_011538319 (OMIM: 603075,607772) PREDICTED: plec ( 416) 220 41.6 0.0029 XP_016871967 (OMIM: 603075,607772) PREDICTED: plec ( 416) 220 41.6 0.0029 NP_536858 (OMIM: 176883) tyrosine-protein phosphat ( 597) 218 41.6 0.0044 XP_011519290 (OMIM: 176883) PREDICTED: tyrosine-pr ( 597) 218 41.6 0.0044 >>NP_055210 (OMIM: 605768) dual adapter for phosphotyros (280 aa) initn: 1895 init1: 1895 opt: 1895 Z-score: 1344.2 bits: 256.6 E(85289): 3.9e-68 Smith-Waterman score: 1895; 100.0% identity (100.0% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK :::::::::::::::::::::::::::::::::::::::: NP_055 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK 250 260 270 280 >>XP_011530142 (OMIM: 605768) PREDICTED: dual adapter fo (267 aa) initn: 1784 init1: 1758 opt: 1758 Z-score: 1249.3 bits: 238.9 E(85289): 7.5e-63 Smith-Waterman score: 1758; 99.2% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK ::::::::::::::::::.. XP_011 AKTGVEADEWIKILRWKLKKQDWSQRS 250 260 >>NP_001293080 (OMIM: 605768) dual adapter for phosphoty (263 aa) initn: 1756 init1: 1756 opt: 1756 Z-score: 1248.0 bits: 238.7 E(85289): 8.9e-63 Smith-Waterman score: 1756; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK :::::::::::::::::: NP_001 AKTGVEADEWIKILRWKLVKDKS 250 260 >>XP_016863512 (OMIM: 605768) PREDICTED: dual adapter fo (258 aa) initn: 1583 init1: 1557 opt: 1557 Z-score: 1110.0 bits: 213.1 E(85289): 4.4e-55 Smith-Waterman score: 1557; 99.6% identity (100.0% similar) in 231 aa overlap (1-231:1-231) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC ::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLLAGVGAYIPA 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK XP_016 LQVWYFHSGHFISVQRPE 250 >>XP_016863513 (OMIM: 605768) PREDICTED: dual adapter fo (258 aa) initn: 1583 init1: 1557 opt: 1557 Z-score: 1110.0 bits: 213.1 E(85289): 4.4e-55 Smith-Waterman score: 1557; 99.6% identity (100.0% similar) in 231 aa overlap (1-231:1-231) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC ::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLLAGVGAYIPA 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK XP_016 LQVWYFHSGHFISVQRPE 250 >>XP_011530144 (OMIM: 605768) PREDICTED: dual adapter fo (258 aa) initn: 1583 init1: 1557 opt: 1557 Z-score: 1110.0 bits: 213.1 E(85289): 4.4e-55 Smith-Waterman score: 1557; 99.6% identity (100.0% similar) in 231 aa overlap (1-231:1-231) 10 20 30 40 50 60 pF1KE0 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC ::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLLAGVGAYIPA 190 200 210 220 230 240 250 260 270 280 pF1KE0 AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK XP_011 LQVWYFHSGHFISVQRPE 250 >>XP_011530145 (OMIM: 605768) PREDICTED: dual adapter fo (158 aa) initn: 1081 init1: 1081 opt: 1081 Z-score: 781.9 bits: 151.7 E(85289): 8.2e-37 Smith-Waterman score: 1081; 100.0% identity (100.0% similar) in 158 aa overlap (123-280:1-158) 100 110 120 130 140 150 pF1KE0 KFGFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGR :::::::::::::::::::::::::::::: XP_011 MVLKHPYPRKVEEPSIYESVRVHTAMQTGR 10 20 30 160 170 180 190 200 210 pF1KE0 TEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTE 40 50 60 70 80 90 220 230 240 250 260 270 pF1KE0 CSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTI 100 110 120 130 140 150 280 pF1KE0 RSRSFIFK :::::::: XP_011 RSRSFIFK >>NP_072179 (OMIM: 139150,605462,608354,608355) ras GTPa (870 aa) initn: 250 init1: 135 opt: 312 Z-score: 239.9 bits: 53.9 E(85289): 1.3e-06 Smith-Waterman score: 312; 28.7% identity (61.0% similar) in 254 aa overlap (35-275:174-414) 10 20 30 40 50 60 pF1KE0 ELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSN :.::..... : ::.. : :.:.: :. NP_072 TNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSD 150 160 170 180 190 200 70 80 90 100 110 120 pF1KE0 ETTGLYSLSVRAKDSVKHFHVEYT-GYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLM .: : ::: :.......:.. : . .: .: ..:. :.. :. .. .. . . NP_072 NTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEG-----Y 210 220 230 240 250 130 140 150 160 170 180 pF1KE0 VLKHPYPRKVEEPSIYESVRVHTAMQTGR--TEDDLVPTAPSLGTKEGYLTKQG-GLVKT ::.: : . .: . ..: . ..: : :.: . . .:.::: :.: : : NP_072 YLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNI----VKKGYLLKKGKG--KR 260 270 280 290 300 310 190 200 210 220 230 pF1KE0 WKTRWFTLHRNE--LKYFK-DQMSPEPIRILDLTECSA-VQFDYSQERVNCFCLVFPFRT ::. .: :. .. : ::. .. . .: ..::. ::. : : : ::: .: . NP_072 WKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFS 320 330 340 350 360 370 240 250 260 270 280 pF1KE0 -----FYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK ::. ..: .:..:.: :. . ..::. . : .. : : NP_072 EEHYIFYFAGETPEQAEDWMKGLQ-AFCNLRKS-SPGTSNKRLRQVSSLVLHIEEAHKLP 380 390 400 410 420 430 NP_072 VKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKD 440 450 460 470 480 490 >>XP_011541827 (OMIM: 139150,605462,608354,608355) PREDI (1018 aa) initn: 242 init1: 135 opt: 312 Z-score: 239.1 bits: 53.9 E(85289): 1.4e-06 Smith-Waterman score: 312; 28.7% identity (61.0% similar) in 254 aa overlap (35-275:351-591) 10 20 30 40 50 60 pF1KE0 ELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSN :.::..... : ::.. : :.:.: :. XP_011 TNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSD 330 340 350 360 370 380 70 80 90 100 110 120 pF1KE0 ETTGLYSLSVRAKDSVKHFHVEYT-GYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLM .: : ::: :.......:.. : . .: .: ..:. :.. :. .. .. . . XP_011 NTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEG-----Y 390 400 410 420 430 130 140 150 160 170 180 pF1KE0 VLKHPYPRKVEEPSIYESVRVHTAMQTGR--TEDDLVPTAPSLGTKEGYLTKQG-GLVKT ::.: : . .: . ..: . ..: : :.: . . .:.::: :.: : : XP_011 YLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNI----VKKGYLLKKGKG--KR 440 450 460 470 480 190 200 210 220 230 pF1KE0 WKTRWFTLHRNE--LKYFK-DQMSPEPIRILDLTECSA-VQFDYSQERVNCFCLVFPFRT ::. .: :. .. : ::. .. . .: ..::. ::. : : : ::: .: . XP_011 WKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFS 490 500 510 520 530 540 240 250 260 270 280 pF1KE0 -----FYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK ::. ..: .:..:.: :. . ..::. . : .. : : XP_011 EEHYIFYFAGETPEQAEDWMKGLQ-AFCNLRKS-SPGTSNKRLRQVSSLVLHIEEAHKLP 550 560 570 580 590 600 XP_011 VKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKD 610 620 630 640 650 660 >>NP_002881 (OMIM: 139150,605462,608354,608355) ras GTPa (1047 aa) initn: 242 init1: 135 opt: 312 Z-score: 239.0 bits: 54.0 E(85289): 1.4e-06 Smith-Waterman score: 312; 28.7% identity (61.0% similar) in 254 aa overlap (35-275:351-591) 10 20 30 40 50 60 pF1KE0 ELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSN :.::..... : ::.. : :.:.: :. NP_002 TNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSD 330 340 350 360 370 380 70 80 90 100 110 120 pF1KE0 ETTGLYSLSVRAKDSVKHFHVEYT-GYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLM .: : ::: :.......:.. : . .: .: ..:. :.. :. .. .. . . NP_002 NTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEG-----Y 390 400 410 420 430 130 140 150 160 170 180 pF1KE0 VLKHPYPRKVEEPSIYESVRVHTAMQTGR--TEDDLVPTAPSLGTKEGYLTKQG-GLVKT ::.: : . .: . ..: . ..: : :.: . . .:.::: :.: : : NP_002 YLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNI----VKKGYLLKKGKG--KR 440 450 460 470 480 190 200 210 220 230 pF1KE0 WKTRWFTLHRNE--LKYFK-DQMSPEPIRILDLTECSA-VQFDYSQERVNCFCLVFPFRT ::. .: :. .. : ::. .. . .: ..::. ::. : : : ::: .: . NP_002 WKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFS 490 500 510 520 530 540 240 250 260 270 280 pF1KE0 -----FYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK ::. ..: .:..:.: :. . ..::. . : .. : : NP_002 EEHYIFYFAGETPEQAEDWMKGLQ-AFCNLRKS-SPGTSNKRLRQVSSLVLHIEEAHKLP 550 560 570 580 590 600 NP_002 VKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKD 610 620 630 640 650 660 280 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:47:16 2016 done: Sat Nov 5 02:47:17 2016 Total Scan time: 7.070 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]