FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0690, 401 aa 1>>>pF1KE0690 401 - 401 aa - 401 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.5882+/-0.0014; mu= -13.5749+/- 0.079 mean_var=480.6195+/-112.264, 0's: 0 Z-trim(109.8): 99 B-trim: 692 in 1/49 Lambda= 0.058502 statistics sampled from 11114 (11169) to 11114 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.343), width: 16 Scan time: 3.110 The best scores are: opt bits E(32554) CCDS13024.2 STK35 gene_id:140901|Hs108|chr20 ( 534) 2668 240.3 3.3e-63 CCDS274.1 PDIK1L gene_id:149420|Hs108|chr1 ( 341) 1532 144.2 1.8e-34 >>CCDS13024.2 STK35 gene_id:140901|Hs108|chr20 (534 aa) initn: 2668 init1: 2668 opt: 2668 Z-score: 1248.3 bits: 240.3 E(32554): 3.3e-63 Smith-Waterman score: 2668; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:134-534) 10 20 30 pF1KE0 METGKDGARRGTQSPERKRRSPVPRAPSTK :::::::::::::::::::::::::::::: CCDS13 PAPPRPRAGRRDEAGGARAAPLLLPPPPAAMETGKDGARRGTQSPERKRRSPVPRAPSTK 110 120 130 140 150 160 40 50 60 70 80 90 pF1KE0 LRPAAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LRPAAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGR 170 180 190 200 210 220 100 110 120 130 140 150 pF1KE0 SGARVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SGARVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNK 230 240 250 260 270 280 160 170 180 190 200 210 pF1KE0 SSQLYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SSQLYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQ 290 300 310 320 330 340 220 230 240 250 260 270 pF1KE0 LTSAIAFLHKNHIVHRDLKPDNILITERSGTPILKVADFGLSKVCAGLAPRGKEGNQDNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LTSAIAFLHKNHIVHRDLKPDNILITERSGTPILKVADFGLSKVCAGLAPRGKEGNQDNK 350 360 370 380 390 400 280 290 300 310 320 330 pF1KE0 NVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKELL 410 420 430 440 450 460 340 350 360 370 380 390 pF1KE0 GTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAFEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAFEL 470 480 490 500 510 520 400 pF1KE0 ETRMDQVTCAA ::::::::::: CCDS13 ETRMDQVTCAA 530 >>CCDS274.1 PDIK1L gene_id:149420|Hs108|chr1 (341 aa) initn: 1491 init1: 527 opt: 1532 Z-score: 732.5 bits: 144.2 E(32554): 1.8e-34 Smith-Waterman score: 1532; 69.3% identity (87.0% similar) in 339 aa overlap (64-397:3-332) 40 50 60 70 80 90 pF1KE0 AAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGRSGA :..:.:.:. :.:::::::::::: ...: CCDS27 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSA 10 20 30 100 110 120 130 140 150 pF1KE0 RVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQ ::::::::: ::::::::: :::::.:.: .: ::...:::.::..:..:.::::..:: CCDS27 RVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSS- 40 50 60 70 80 90 160 170 180 190 200 210 pF1KE0 LYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQLTS :::.::::::::: : . ::::::.::.:::.:.:.:::.:. :: ::::::.: CCDS27 LYLQLVETSLKGE-IAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSS 100 110 120 130 140 150 220 230 240 250 260 pF1KE0 AIAFLHKNHIVHRDLKPDNILITE-RSGT----PILKVADFGLSKVCAGLAPRGKEGNQD :.::::::.:.:::::::::::.. : : : ::::::::::::.. :.. CCDS27 ALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPTLKVADFGLSKVCSA------SGQNP 160 170 180 190 200 270 280 290 300 310 320 pF1KE0 NKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKE .. :.::: .::.:::.:::::::::::::::::::::::::::::.:::::::.::::: CCDS27 EEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGIIIWAMLERITFIDTETKKE 210 220 230 240 250 260 330 340 350 360 370 380 pF1KE0 LLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAF :::.:.::::::::::::::::::::: :: :.. ::. .:::.:.::::::::::::: CCDS27 LLGSYVKQGTEIVPVGEALLENPKMELLIPVKKK-SMNGRMKQLIKEMLAANPQDRPDAF 270 280 290 300 310 320 390 400 pF1KE0 ELETRMDQVTCAA ::: :. :. CCDS27 ELELRLVQIAFKDSSWET 330 340 401 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:59:19 2016 done: Sat Nov 5 17:59:19 2016 Total Scan time: 3.110 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]