FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0691, 281 aa 1>>>pF1KE0691 281 - 281 aa - 281 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4389+/-0.000816; mu= 11.4832+/- 0.049 mean_var=193.5189+/-46.175, 0's: 0 Z-trim(113.8): 273 B-trim: 716 in 1/54 Lambda= 0.092196 statistics sampled from 14076 (14444) to 14076 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.444), width: 16 Scan time: 2.800 The best scores are: opt bits E(32554) CCDS56519.1 ZNF783 gene_id:100289678|Hs108|chr7 ( 546) 1819 254.3 1.4e-67 CCDS5894.1 ZNF398 gene_id:57541|Hs108|chr7 ( 642) 948 138.5 1.2e-32 CCDS43675.1 ZNF777 gene_id:27153|Hs108|chr7 ( 831) 911 133.7 4.2e-31 CCDS78284.1 ZNF282 gene_id:8427|Hs108|chr7 ( 463) 853 125.7 6.3e-29 CCDS5895.1 ZNF282 gene_id:8427|Hs108|chr7 ( 671) 853 125.9 7.8e-29 CCDS5896.1 ZNF212 gene_id:7988|Hs108|chr7 ( 495) 846 124.8 1.2e-28 CCDS5897.1 ZNF746 gene_id:155061|Hs108|chr7 ( 644) 571 88.4 1.5e-17 CCDS55180.1 ZNF746 gene_id:155061|Hs108|chr7 ( 645) 571 88.4 1.5e-17 >>CCDS56519.1 ZNF783 gene_id:100289678|Hs108|chr7 (546 aa) initn: 1802 init1: 1802 opt: 1819 Z-score: 1326.5 bits: 254.3 E(32554): 1.4e-67 Smith-Waterman score: 1819; 96.1% identity (98.6% similar) in 283 aa overlap (1-281:1-283) 10 20 30 40 50 60 pF1KE0 MAEAAPARDPETDKHTEDQSPSTPLPQPAAEKNSYLYSTEITLWTVVAAIQALEKKVDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MAEAAPARDPETDKHTEDQSPSTPLPQPAAEKNSYLYSTEITLWTVVAAIQALEKKVDSC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LTRLLTLEGRTGTAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LTRLLTLEGRTGTAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RNRNFWILRLPPGSKGEAPKVPVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 RNRNFWILRLPPGSKGEAPKVPVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SLDYAISKPDILTRIERGEEPCLDRWGQEKGNEVEVGRPRMMGTGLPPYPEHLTSPLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SLDYAISKPDILTRIERGEEPCLDRWGQEKGNEVEVGRPRMMGTGLPPYPEHLTSPLSPA 190 200 210 220 230 240 250 260 270 280 pF1KE0 QEELKEGQAPKQQQDSEARVAPAGPEAG--LALRTDLQGEAQI :::::::::::::::::::::::::::: .:..:. :.: .. CCDS56 QEELKEGQAPKQQQDSEARVAPAGPEAGGGVAIKTEAQSEDEMTPERLFLGVSRGQTECR 250 260 270 280 290 300 CCDS56 IPRGPRNRPGGPSRHQAQGMPRVRAGEPRPPGASGETPRVLSRRRQRAFPCPDCGQSFRL 310 320 330 340 350 360 >>CCDS5894.1 ZNF398 gene_id:57541|Hs108|chr7 (642 aa) initn: 948 init1: 914 opt: 948 Z-score: 699.6 bits: 138.5 E(32554): 1.2e-32 Smith-Waterman score: 948; 54.7% identity (75.4% similar) in 285 aa overlap (1-281:1-280) 10 20 30 40 50 60 pF1KE0 MAEAAPARDPETDKHTEDQSPSTPLPQPAAEKNSYLYSTEITLWTVVAAIQALEKKVDSC ::::::: : :.. . ::: : : ....: .. :.:::::::.::.:.::. CCDS58 MAEAAPAPTSEWDSECLTSLQPLPLPTPPAANEAHLQTAAISLWTVVAAVQAIERKVEIH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LTRLLTLEGRTGTAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLL ::: :::::::::::::.::::..:.:::::::::::::::::::::::::::.:::: CCDS58 SRRLLHLEGRTGTAEKKLASCEKTVTELGNQLEGKWAVLGTLLQEYGLLQRRLENLENLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RNRNFWILRLPPGSKGEAPKVPVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLV ::::::::::::: ::. :::::.::::..::: :: :::.:::::::..:.::::.:. CCDS58 RNRNFWILRLPPGIKGDIPKVPVAFDDVSIYFSTPEWEKLEEWQKELYKNIMKGNYESLI 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 SLDYAISKPDILTRIE-RGEEPCLDRWGQEKGNEVEVG---RPRMMGTGLPPYPEHLTSP :.::::..::.:..:. .::. :. : :. .:. . .: . . . . .. : CCDS58 SMDYAINQPDVLSQIQPEGEHNTEDQAGPEE-SEIPTDPSEEPGISTSDILSWIKQEEEP 190 200 210 220 230 240 250 260 270 280 pF1KE0 LSPAQEELKEGQAPKQQQDSEARVAPAGPEAGLALRTDLQGEAQI : : ::... :. .: : : ::: :..: :. . CCDS58 QVGAPPESKESDVYKSTYADEELVIKA---EGLA-RSSLCPEVPVPFSSPPAAAKDAFSD 240 250 260 270 280 290 CCDS58 VAFKSQQSTSMTPFGRPATDLPEASEGQVTFTQLGSYPLPPPVGEQVFSCHHCGKNLSQD 300 310 320 330 340 350 >>CCDS43675.1 ZNF777 gene_id:27153|Hs108|chr7 (831 aa) initn: 856 init1: 856 opt: 911 Z-score: 671.8 bits: 133.7 E(32554): 4.2e-31 Smith-Waterman score: 911; 56.8% identity (75.5% similar) in 273 aa overlap (10-272:147-416) 10 20 30 pF1KE0 MAEAAPARDPETDKHTEDQSPSTPLPQP-----AAEKNS :::: ::: . : :..:.. CCDS43 LLSHSPHHQEAPVHSPEAPEKDPLTLSPTVPETDMDPLLQSPVSQKDTPFQISSAVQKEQ 120 130 140 150 160 170 40 50 60 70 80 90 pF1KE0 YLYSTEITLWTVVAAIQALEKKVDSCLTRLLTLEGRTGTAEKKLADCEKTAVEFGNQLEG : ..::: .: ::.::.:.:... ::::::::::: :::.::::::::::.:.::. CCDS43 PLPTAEITRLAVWAAVQAVERKLEAQAMRLLTLEGRTGTNEKKIADCEKTAVEFANHLES 180 190 200 210 220 230 100 110 120 130 140 150 pF1KE0 KWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGEAPKVPVTFDDVAVYFSE ::.::::::::::::::::::.::::.:::::::::::::.::.::::::::::::.::: CCDS43 KWVVLGTLLQEYGLLQRRLENMENLLKNRNFWILRLPPGSNGEVPKVPVTFDDVAVHFSE 240 250 260 270 280 290 160 170 180 190 200 210 pF1KE0 LEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPDILTRIERGEEPCLDRWGQEKGNEV :::.: .:::::::.:::::::.:::.::::::::.....::::.: ... :: ..: CCDS43 QEWGNLSEWQKELYKNVMRGNYESLVSMDYAISKPDLMSQMERGERPTMQE--QEDSEEG 300 310 320 330 340 350 220 230 240 250 260 pF1KE0 EVGR-PRMMGTGLPPYPEHLTSPLSPAQEELKE---GQAPKQQ-QDSEARVAPAGPEAGL :. : :. : :. . . : : ::. .. :::: : : . : CCDS43 ETPTDPSAAHDGIVIKIEVQTNDEGSESLETPEPLMGQVEEHGFQDSELG-DPCGEQPDL 360 370 380 390 400 410 270 280 pF1KE0 ALRTDLQGEAQI .. CCDS43 DMQEPENTLEESTEGSSEFSELKQMLVQQRNCTEGIVIKTEEQDEEEEEEEEDELPQHLQ 420 430 440 450 460 470 >>CCDS78284.1 ZNF282 gene_id:8427|Hs108|chr7 (463 aa) initn: 827 init1: 795 opt: 853 Z-score: 632.9 bits: 125.7 E(32554): 6.3e-29 Smith-Waterman score: 871; 57.3% identity (75.1% similar) in 253 aa overlap (1-242:47-287) 10 20 pF1KE0 MAEAAP---ARDPETDKHTEDQSPSTPLPQ :::. : :.. . : . :.:. CCDS78 GLGLDSGSWSWAQALPPEEVCHQEPALRGEMAEGMPPMQAQEWDMDARRPMPFQFPPFPD 20 30 40 50 60 70 30 40 50 60 70 80 pF1KE0 PAA------EKNSYLYSTEITLWTVVAAIQALEKKVDSCLTRLLTLEGRTGTAEKKLADC : .. : ..::.::::::::::.:.:::. ..::.::::::::::::::: CCDS78 RAPVFPDRMMREPQLPTAEISLWTVVAAIQAVERKVDAQASQLLNLEGRTGTAEKKLADC 80 90 100 110 120 130 90 100 110 120 130 140 pF1KE0 EKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGEAPKV :::::::::..:.:::::::::::::::::::::.::::::::::.:::::::::::::: CCDS78 EKTAVEFGNHMESKWAVLGTLLQEYGLLQRRLENLENLLRNRNFWVLRLPPGSKGEAPKV 140 150 160 170 180 190 150 160 170 180 190 pF1KE0 PVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLVSLDY--AISKPDILTRIERGE :::: :.:::::: :: .:..::::::..... ::.::.::: .. ::: .. : : CCDS78 PVTFVDIAVYFSEDEWKNLDEWQKELYNNLVKENYKTLMSLDAEGSVPKPDAPVQAEPRE 200 210 220 230 240 250 200 210 220 230 240 250 pF1KE0 EPCLDRWGQEKGNEVEVGRPRMMGTGLPPYPEHLTSPLSPAQEELKEGQAPKQQQDSEAR :::. : :.. .: :. : :: . :: :::. CCDS78 EPCV--WEQRHPEEREI----------PMDPEAGAEPLVPAQDASSQVKREDTLCVRGQR 260 270 280 290 300 260 270 280 pF1KE0 VAPAGPEAGLALRTDLQGEAQI CCDS78 GLEERAIPTESITDSPISAQDLLSRIKQEEHQCVWDQQDLADRDIPTDPNSESLISAHDI 310 320 330 340 350 360 >>CCDS5895.1 ZNF282 gene_id:8427|Hs108|chr7 (671 aa) initn: 827 init1: 795 opt: 853 Z-score: 631.1 bits: 125.9 E(32554): 7.8e-29 Smith-Waterman score: 871; 57.3% identity (75.1% similar) in 253 aa overlap (1-242:47-287) 10 20 pF1KE0 MAEAAP---ARDPETDKHTEDQSPSTPLPQ :::. : :.. . : . :.:. CCDS58 GLGLDSGSWSWAQALPPEEVCHQEPALRGEMAEGMPPMQAQEWDMDARRPMPFQFPPFPD 20 30 40 50 60 70 30 40 50 60 70 80 pF1KE0 PAA------EKNSYLYSTEITLWTVVAAIQALEKKVDSCLTRLLTLEGRTGTAEKKLADC : .. : ..::.::::::::::.:.:::. ..::.::::::::::::::: CCDS58 RAPVFPDRMMREPQLPTAEISLWTVVAAIQAVERKVDAQASQLLNLEGRTGTAEKKLADC 80 90 100 110 120 130 90 100 110 120 130 140 pF1KE0 EKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGEAPKV :::::::::..:.:::::::::::::::::::::.::::::::::.:::::::::::::: CCDS58 EKTAVEFGNHMESKWAVLGTLLQEYGLLQRRLENLENLLRNRNFWVLRLPPGSKGEAPKV 140 150 160 170 180 190 150 160 170 180 190 pF1KE0 PVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLVSLDY--AISKPDILTRIERGE :::: :.:::::: :: .:..::::::..... ::.::.::: .. ::: .. : : CCDS58 PVTFVDIAVYFSEDEWKNLDEWQKELYNNLVKENYKTLMSLDAEGSVPKPDAPVQAEPRE 200 210 220 230 240 250 200 210 220 230 240 250 pF1KE0 EPCLDRWGQEKGNEVEVGRPRMMGTGLPPYPEHLTSPLSPAQEELKEGQAPKQQQDSEAR :::. : :.. .: :. : :: . :: :::. CCDS58 EPCV--WEQRHPEEREI----------PMDPEAGAEPLVPAQDASSQVKREDTLCVRGQR 260 270 280 290 300 260 270 280 pF1KE0 VAPAGPEAGLALRTDLQGEAQI CCDS58 GLEERAIPTESITDSPISAQDLLSRIKQEEHQCVWDQQDLADRDIPTDPNSESLISAHDI 310 320 330 340 350 360 >>CCDS5896.1 ZNF212 gene_id:7988|Hs108|chr7 (495 aa) initn: 882 init1: 819 opt: 846 Z-score: 627.5 bits: 124.8 E(32554): 1.2e-28 Smith-Waterman score: 846; 73.1% identity (87.4% similar) in 182 aa overlap (1-182:1-180) 10 20 30 40 50 60 pF1KE0 MAEAAPARDPETDKHTEDQSPSTPLPQPAAEKNSYLYSTEITLWTVVAAIQALEKKVDSC :::.:::: . :. :. ::. :.::.::. .:::.::::::::::.:::..: CCDS58 MAESAPAR--HRRKRRSTPLTSSTLPSQATEKSSYFQTTEISLWTVVAAIQAVEKKMESQ 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 LTRLLTLEGRTGTAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLL .:: .::::::::::::::::: :::::::::::::::::::::::::::::::::::: CCDS58 AARLQSLEGRTGTAEKKLADCEKMAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 RNRNFWILRLPPGSKGEAPKVPVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLV ::::::::::::::::::::: .... .: :.: :: .:::::::::..::..:::::: CCDS58 RNRNFWILRLPPGSKGEAPKVSRSLENDGVCFTEQEWENLEDWQKELYRNVMESNYETLV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 SLDYAISKPDILTRIERGEEPCLDRWGQEKGNEVEVGRPRMMGTGLPPYPEHLTSPLSPA :: CCDS58 SLKVLGQTEGEAELGTEMLGDLEEEGPGGAHPAGGVMIKQELQYTQEGPADLPGEFSCIA 180 190 200 210 220 230 >>CCDS5897.1 ZNF746 gene_id:155061|Hs108|chr7 (644 aa) initn: 600 init1: 571 opt: 571 Z-score: 428.6 bits: 88.4 E(32554): 1.5e-17 Smith-Waterman score: 864; 67.1% identity (79.5% similar) in 210 aa overlap (41-249:9-201) 20 30 40 50 60 70 pF1KE0 ETDKHTEDQSPSTPLPQPAAEKNSYLYSTEITLWTVVAAIQALEKKVDSCLTRLLTLEGR :. ::..:.:::.:.:..: .:::.:::: CCDS58 MAEAVAAPISPWTMAATIQAMERKIESQAARLLSLEGR 10 20 30 80 90 100 110 120 130 pF1KE0 TGTAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRL :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TGMAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 PPGSKGEAPKVPVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPD :::::::.:: ::::::::::::::::::::::::::::::::::. CCDS58 PPGSKGESPK---------------EWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPE 100 110 120 130 140 200 210 220 230 240 pF1KE0 ILTRIERGEEPCLDRWGQEKGNEVEVGRPRMMGTGLP-PYPEHLTSPLSPAQEELKEGQA .:..::.:.::: : : .: : : :.: : : :. : . . .. .:.: :: CCDS58 VLSQIEQGKEPCNWRRPGPKIPDVPVD-PSP-GSGPPVPAPDLLMQIKQEGELQLQEQQA 150 160 170 180 190 200 250 260 270 280 pF1KE0 PKQQQDSEARVAPAGPEAGLALRTDLQGEAQI CCDS58 LGVEAWAAGQPDIGEEPWGLSQLDSGAGDISTDATSGVHSNFSTTIPPTSWQTDLPPHHP 210 220 230 240 250 260 >>CCDS55180.1 ZNF746 gene_id:155061|Hs108|chr7 (645 aa) initn: 600 init1: 571 opt: 571 Z-score: 428.6 bits: 88.4 E(32554): 1.5e-17 Smith-Waterman score: 864; 67.1% identity (79.5% similar) in 210 aa overlap (41-249:9-201) 20 30 40 50 60 70 pF1KE0 ETDKHTEDQSPSTPLPQPAAEKNSYLYSTEITLWTVVAAIQALEKKVDSCLTRLLTLEGR :. ::..:.:::.:.:..: .:::.:::: CCDS55 MAEAVAAPISPWTMAATIQAMERKIESQAARLLSLEGR 10 20 30 80 90 100 110 120 130 pF1KE0 TGTAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRL :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TGMAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 PPGSKGEAPKVPVTFDDVAVYFSELEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPD :::::::.:: ::::::::::::::::::::::::::::::::::. CCDS55 PPGSKGESPK---------------EWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPE 100 110 120 130 140 200 210 220 230 240 pF1KE0 ILTRIERGEEPCLDRWGQEKGNEVEVGRPRMMGTGLP-PYPEHLTSPLSPAQEELKEGQA .:..::.:.::: : : .: : : :.: : : :. : . . .. .:.: :: CCDS55 VLSQIEQGKEPCNWRRPGPKIPDVPVD-PSP-GSGPPVPAPDLLMQIKQEGELQLQEQQA 150 160 170 180 190 200 250 260 270 280 pF1KE0 PKQQQDSEARVAPAGPEAGLALRTDLQGEAQI CCDS55 LGVEAWAAGQPDIGEEPWGLSQLDSGAGDISTDATSGVHSNFSTTIPPTSWQTDLPPHHP 210 220 230 240 250 260 281 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:47:52 2016 done: Sat Nov 5 02:47:52 2016 Total Scan time: 2.800 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]