FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0695, 284 aa 1>>>pF1KE0695 284 - 284 aa - 284 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1952+/-0.000357; mu= 15.7965+/- 0.022 mean_var=65.3183+/-13.821, 0's: 0 Z-trim(113.9): 26 B-trim: 261 in 2/52 Lambda= 0.158693 statistics sampled from 23519 (23533) to 23519 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.276), width: 16 Scan time: 7.460 The best scores are: opt bits E(85289) NP_663629 (OMIM: 612896) RAD52 motif-containing pr ( 284) 1886 440.4 1.8e-123 NP_001156602 (OMIM: 612896) RAD52 motif-containing ( 261) 1681 393.5 2.2e-109 XP_011522811 (OMIM: 612896) PREDICTED: RAD52 motif ( 252) 1463 343.6 2.3e-94 NP_001030008 (OMIM: 612896) RAD52 motif-containing ( 236) 1458 342.4 4.8e-94 NP_001156593 (OMIM: 612896) RAD52 motif-containing ( 251) 1261 297.3 1.9e-80 NP_001156594 (OMIM: 612896) RAD52 motif-containing ( 228) 1056 250.4 2.4e-66 NP_001156592 (OMIM: 612896) RAD52 motif-containing ( 166) 882 210.4 1.8e-54 NP_001317123 (OMIM: 612896) RAD52 motif-containing ( 139) 881 210.2 1.8e-54 NP_001156597 (OMIM: 612896) RAD52 motif-containing ( 116) 676 163.2 2.1e-40 NP_001156596 (OMIM: 612896) RAD52 motif-containing ( 143) 677 163.5 2.1e-40 XP_011523080 (OMIM: 616557) PREDICTED: leucine-ric ( 837) 145 42.1 0.0042 >>NP_663629 (OMIM: 612896) RAD52 motif-containing protei (284 aa) initn: 1886 init1: 1886 opt: 1886 Z-score: 2337.8 bits: 440.4 E(85289): 1.8e-123 Smith-Waterman score: 1886; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284) 10 20 30 40 50 60 pF1KE0 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 EEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGV 190 200 210 220 230 240 250 260 270 280 pF1KE0 RCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD :::::::::::::::::::::::::::::::::::::::::::: NP_663 RCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 250 260 270 280 >>NP_001156602 (OMIM: 612896) RAD52 motif-containing pro (261 aa) initn: 1681 init1: 1681 opt: 1681 Z-score: 2084.7 bits: 393.5 E(85289): 2.2e-109 Smith-Waterman score: 1681; 99.6% identity (100.0% similar) in 253 aa overlap (32-284:9-261) 10 20 30 40 50 60 pF1KE0 AELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPGF .::::::::::::::::::::::::::::: NP_001 MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGF 10 20 30 70 80 90 100 110 120 pF1KE0 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 FGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 EPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGVR 160 170 180 190 200 210 250 260 270 280 pF1KE0 CEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD ::::::::::::::::::::::::::::::::::::::::::: NP_001 CEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 220 230 240 250 260 >>XP_011522811 (OMIM: 612896) PREDICTED: RAD52 motif-con (252 aa) initn: 1463 init1: 1463 opt: 1463 Z-score: 1815.2 bits: 343.6 E(85289): 2.3e-94 Smith-Waterman score: 1463; 99.1% identity (99.6% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KE0 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGV :::::::::::::::::::::::::::::::::::::::::: .: XP_011 EEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLGGGPDCSQLSNLGNSPSS 190 200 210 220 230 240 250 260 270 280 pF1KE0 RCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD XP_011 ESLTSLVINCQV 250 >>NP_001030008 (OMIM: 612896) RAD52 motif-containing pro (236 aa) initn: 1458 init1: 1458 opt: 1458 Z-score: 1809.4 bits: 342.4 E(85289): 4.8e-94 Smith-Waterman score: 1458; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222) 10 20 30 40 50 60 pF1KE0 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGV :::::::::::::::::::::::::::::::::::::::::: NP_001 EEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLGKTVLIILEVLQFQ 190 200 210 220 230 250 260 270 280 pF1KE0 RCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD >>NP_001156593 (OMIM: 612896) RAD52 motif-containing pro (251 aa) initn: 1675 init1: 1261 opt: 1261 Z-score: 1565.2 bits: 297.3 E(85289): 1.9e-80 Smith-Waterman score: 1613; 88.4% identity (88.4% similar) in 284 aa overlap (1-284:1-251) 10 20 30 40 50 60 pF1KE0 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGV ::::::::: :::::::::::::::::: NP_001 EEPMDKVEE---------------------------------ESGKIAVEYRPSEDIVGV 190 200 250 260 270 280 pF1KE0 RCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD :::::::::::::::::::::::::::::::::::::::::::: NP_001 RCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 210 220 230 240 250 >>NP_001156594 (OMIM: 612896) RAD52 motif-containing pro (228 aa) initn: 1470 init1: 1056 opt: 1056 Z-score: 1312.2 bits: 250.4 E(85289): 2.4e-66 Smith-Waterman score: 1408; 86.6% identity (87.0% similar) in 253 aa overlap (32-284:9-228) 10 20 30 40 50 60 pF1KE0 AELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPGF .::::::::::::::::::::::::::::: NP_001 MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGF 10 20 30 70 80 90 100 110 120 pF1KE0 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 FGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 EPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGVR :::::::: ::::::::::::::::::: NP_001 EPMDKVEE---------------------------------ESGKIAVEYRPSEDIVGVR 160 170 180 250 260 270 280 pF1KE0 CEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD ::::::::::::::::::::::::::::::::::::::::::: NP_001 CEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 190 200 210 220 >>NP_001156592 (OMIM: 612896) RAD52 motif-containing pro (166 aa) initn: 882 init1: 882 opt: 882 Z-score: 1099.0 bits: 210.4 E(85289): 1.8e-54 Smith-Waterman score: 882; 99.3% identity (100.0% similar) in 134 aa overlap (1-134:1-134) 10 20 30 40 50 60 pF1KE0 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV :::::::::::::. NP_001 YFGFNGCSKRIIKVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 130 140 150 160 >>NP_001317123 (OMIM: 612896) RAD52 motif-containing pro (139 aa) initn: 881 init1: 881 opt: 881 Z-score: 1098.9 bits: 210.2 E(85289): 1.8e-54 Smith-Waterman score: 881; 100.0% identity (100.0% similar) in 133 aa overlap (1-133:1-133) 10 20 30 40 50 60 pF1KE0 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLV ::::::::::::: NP_001 YFGFNGCSKRIIKDHYHSL 130 >>NP_001156597 (OMIM: 612896) RAD52 motif-containing pro (116 aa) initn: 676 init1: 676 opt: 676 Z-score: 846.4 bits: 163.2 E(85289): 2.1e-40 Smith-Waterman score: 676; 99.0% identity (100.0% similar) in 102 aa overlap (32-133:9-110) 10 20 30 40 50 60 pF1KE0 AELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPGF .::::::::::::::::::::::::::::: NP_001 MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGF 10 20 30 70 80 90 100 110 120 pF1KE0 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 FGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVE :::::::::::: NP_001 FGFNGCSKRIIKDHYHSL 100 110 >>NP_001156596 (OMIM: 612896) RAD52 motif-containing pro (143 aa) initn: 676 init1: 676 opt: 677 Z-score: 846.3 bits: 163.5 E(85289): 2.1e-40 Smith-Waterman score: 677; 98.1% identity (100.0% similar) in 103 aa overlap (32-134:9-111) 10 20 30 40 50 60 pF1KE0 AELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPGF .::::::::::::::::::::::::::::: NP_001 MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGF 10 20 30 70 80 90 100 110 120 pF1KE0 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 FGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVE ::::::::::::. NP_001 FGFNGCSKRIIKVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 100 110 120 130 140 284 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:49:43 2016 done: Sat Nov 5 02:49:44 2016 Total Scan time: 7.460 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]