FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0699, 4563 aa 1>>>pF1KE0699 4563 - 4563 aa - 4563 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5264+/-0.000751; mu= 23.0757+/- 0.047 mean_var=92.9371+/-19.160, 0's: 0 Z-trim(102.0): 94 B-trim: 28 in 1/51 Lambda= 0.133039 statistics sampled from 10899 (10947) to 10899 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.41), E-opt: 0.2 (0.128), width: 16 Scan time: 33.450 The best scores are: opt bits E(85289) NP_000375 (OMIM: 107730,144010,615558) apolipoprot (4563) 29313 5639.3 0 XP_016882535 (OMIM: 145900,605725,614895) PREDICTE (1427) 227 56.5 5.6e-06 XP_016882536 (OMIM: 145900,605725,614895) PREDICTE (1427) 227 56.5 5.6e-06 NP_870998 (OMIM: 145900,605725,614895) periaxin is (1461) 227 56.5 5.7e-06 XP_011525473 (OMIM: 145900,605725,614895) PREDICTE (1461) 227 56.5 5.7e-06 >>NP_000375 (OMIM: 107730,144010,615558) apolipoprotein (4563 aa) initn: 29313 init1: 29313 opt: 29313 Z-score: 30391.5 bits: 5639.3 E(85289): 0 Smith-Waterman score: 29313; 100.0% identity (100.0% similar) in 4563 aa overlap (1-4563:1-4563) 10 20 30 40 50 60 pF1KE0 MDPPRPALLALLALPALLLLLLAGARAEEEMLENVSLVCPKDATRFKHLRKYTYNYEAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MDPPRPALLALLALPALLLLLLAGARAEEEMLENVSLVCPKDATRFKHLRKYTYNYEAES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCILKEVYGFNPEGKALLKKTKNSE ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_000 SSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCTLKEVYGFNPEGKALLKKTKNSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGIISALLVPPETEEAKQVLFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGIISALLVPPETEEAKQVLFLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRTGISPLALIKGMTRPLSTLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRTGISPLALIKGMTRPLSTLIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVAQVTQTLKLEDTPKINSRFFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVAQVTQTLKLEDTPKINSRFFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFNKLVTELRGLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFNKLVTELRGLSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PSAQQLREIFNMARDQRSRATLYALSHAVNNYHKTNPTGTQELLDIANYLMEQIQDDCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PSAQQLREIFNMARDQRSRATLYALSHAVNNYHKTNPTGTQELLDIANYLMEQIQDDCTG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DEDYTYLILRVIGNMGQTMEQLTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DEDYTYLILRVIGNMGQTMEQLTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDKD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 QEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQILPWEQNEQVKNFVASHIANI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQILPWEQNEQVKNFVASHIANI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 LNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYQLYKSVSLPSLDPASAKIEGNLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYQLYKSVSLPSLDPASAKIEGNLI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 FDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEPTLEALFGKQGFFPDSVNKALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEPTLEALFGKQGFFPDSVNKALY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 WVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVEKLIKDLKSKEVPEARAYLRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVEKLIKDLKSKEVPEARAYLRIL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 GEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 GAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 MNTNFFHESGLEAHVALKAGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MNTNFFHESGLEAHVALKAGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 QSWSVCKQVFPGLNYCTSGAYSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QSWSVCKQVFPGLNYCTSGAYSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 ELQREDRALVDTLKFVTQAEGAKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ELQREDRALVDTLKFVTQAEGAKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVN 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 DESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERKIKGVISIPRLQAEARSEILAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERKIKGVISIPRLQAEARSEILAH 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 WSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSDY 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 PKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 FNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 LHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNTST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNTST 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE0 DHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFTLSCDGSLRHKFLDSNIKFSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFTLSCDGSLRHKFLDSNIKFSHV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE0 EKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHLFVKEVKIDGQFRVSSFYAKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHLFVKEVKIDGQFRVSSFYAKGT 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE0 YGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNTAS 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE0 LKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGSLN 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE0 SHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLENELNAELGLSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLENELNAELGLSGA 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE0 SMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKVSQEGLKLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKVSQEGLKLSN 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE0 DMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTVNLQLQPYSLVTTLNSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTVNLQLQPYSLVTTLNSD 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE0 LKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHIYAISSAALSASYKADTVAKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHIYAISSAALSASYKADTVAKVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE0 GVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRSVMAPFTMTIDAHTNGNGKLALW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRSVMAPFTMTIDAHTNGNGKLALW 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE0 GEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRKSISAALEHKVSALLTPAEQTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRKSISAALEHKVSALLTPAEQTGT 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KE0 WKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLADLTLLDSPIKVPLLLSEPINIIDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLADLTLLDSPIKVPLLLSEPINIIDAL 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KE0 EMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFFETLQEYFERNRQTIIVVLENVQRNLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFFETLQEYFERNRQTIIVVLENVQRNLK 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KE0 HINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSHAKEKLTALTKKYRITENDIQIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSHAKEKLTALTKKYRITENDIQIAL 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KE0 DDAKINFNEKLSQLQTYMIQFDQYIKDSYDLHDLKIAIANIIDEIIEKLKSLDEHYHIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DDAKINFNEKLSQLQTYMIQFDQYIKDSYDLHDLKIAIANIIDEIIEKLKSLDEHYHIRV 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KE0 NLVKTIHDLHLFIENIDFNKSGSSTASWIQNVDTKYQIRIQIQEKLQQLKRHIQNIDIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NLVKTIHDLHLFIENIDFNKSGSSTASWIQNVDTKYQIRIQIQEKLQQLKRHIQNIDIQH 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KE0 LAGKLKQHIEAIDVRVLLDQLGTTISFERINDVLEHVKHFVINLIGDFEVAEKINAFRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LAGKLKQHIEAIDVRVLLDQLGTTISFERINDVLEHVKHFVINLIGDFEVAEKINAFRAK 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KE0 VHELIERYEVDQQIQVLMDKLVELAHQYKLKETIQKLSNVLQQVKIKDYFEKLVGFIDDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VHELIERYEVDQQIQVLMDKLVELAHQYKLKETIQKLSNVLQQVKIKDYFEKLVGFIDDA 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KE0 VKKLNELSFKTFIEDVNKFLDMLIKKLKSFDYHQFVDETNDKIREVTQRLNGEIQALELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VKKLNELSFKTFIEDVNKFLDMLIKKLKSFDYHQFVDETNDKIREVTQRLNGEIQALELP 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 2520 pF1KE0 QKAEALKLFLEETKATVAVYLESLQDTKITLIINWLQEALSSASLAHMKAKFRETLEDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QKAEALKLFLEETKATVAVYLESLQDTKITLIINWLQEALSSASLAHMKAKFRETLEDTR 2470 2480 2490 2500 2510 2520 2530 2540 2550 2560 2570 2580 pF1KE0 DRMYQMDIQQELQRYLSLVGQVYSTLVTYISDWWTLAAKNLTDFAEQYSIQDWAKRMKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DRMYQMDIQQELQRYLSLVGQVYSTLVTYISDWWTLAAKNLTDFAEQYSIQDWAKRMKAL 2530 2540 2550 2560 2570 2580 2590 2600 2610 2620 2630 2640 pF1KE0 VEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPDFIVPLTDLRIPSVQINFKDLKNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPDFIVPLTDLRIPSVQINFKDLKNIK 2590 2600 2610 2620 2630 2640 2650 2660 2670 2680 2690 2700 pF1KE0 IPSRFSTPEFTILNTFHIPSFTIDFVEMKVKIIRTIDQMLNSELQWPVPDIYLRDLKVED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IPSRFSTPEFTILNTFHIPSFTIDFVEMKVKIIRTIDQMLNSELQWPVPDIYLRDLKVED 2650 2660 2670 2680 2690 2700 2710 2720 2730 2740 2750 2760 pF1KE0 IPLARITLPDFRLPEIAIPEFIIPTLNLNDFQVPDLHIPEFQLPHISHTIEVPTFGKLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IPLARITLPDFRLPEIAIPEFIIPTLNLNDFQVPDLHIPEFQLPHISHTIEVPTFGKLYS 2710 2720 2730 2740 2750 2760 2770 2780 2790 2800 2810 2820 pF1KE0 ILKIQSPLFTLDANADIGNGTTSANEAGIAASITAKGESKLEVLNFDFQANAQLSNPKIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ILKIQSPLFTLDANADIGNGTTSANEAGIAASITAKGESKLEVLNFDFQANAQLSNPKIN 2770 2780 2790 2800 2810 2820 2830 2840 2850 2860 2870 2880 pF1KE0 PLALKESVKFSSKYLRTEHGSEMLFFGNAIEGKSNTVASLHTEKNTLELSNGVIVKINNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PLALKESVKFSSKYLRTEHGSEMLFFGNAIEGKSNTVASLHTEKNTLELSNGVIVKINNQ 2830 2840 2850 2860 2870 2880 2890 2900 2910 2920 2930 2940 pF1KE0 LTLDSNTKYFHKLNIPKLDFSSQADLRNEIKTLLKAGHIAWTSSGKGSWKWACPRFSDEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LTLDSNTKYFHKLNIPKLDFSSQADLRNEIKTLLKAGHIAWTSSGKGSWKWACPRFSDEG 2890 2900 2910 2920 2930 2940 2950 2960 2970 2980 2990 3000 pF1KE0 THESQISFTIEGPLTSFGLSNKINSKHLRVNQNLVYESGSLNFSKLEIQSQVDSQHVGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 THESQISFTIEGPLTSFGLSNKINSKHLRVNQNLVYESGSLNFSKLEIQSQVDSQHVGHS 2950 2960 2970 2980 2990 3000 3010 3020 3030 3040 3050 3060 pF1KE0 VLTAKGMALFGEGKAEFTGRHDAHLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VLTAKGMALFGEGKAEFTGRHDAHLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVRF 3010 3020 3030 3040 3050 3060 3070 3080 3090 3100 3110 3120 pF1KE0 PLRLTGKIDFLNNYALFLSPSAQQASWQVSARFNQYKYNQNFSAGNNENIMEAHVGINGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PLRLTGKIDFLNNYALFLSPSAQQASWQVSARFNQYKYNQNFSAGNNENIMEAHVGINGE 3070 3080 3090 3100 3110 3120 3130 3140 3150 3160 3170 3180 pF1KE0 ANLDFLNIPLTIPEMRLPYTIITTPPLKDFSLWEKTGLKEFLKTTKQSFDLSVKAQYKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ANLDFLNIPLTIPEMRLPYTIITTPPLKDFSLWEKTGLKEFLKTTKQSFDLSVKAQYKKN 3130 3140 3150 3160 3170 3180 3190 3200 3210 3220 3230 3240 pF1KE0 KHRHSITNPLAVLCEFISQSIKSFDRHFEKNRNNALDFVTKSYNETKIKFDKYKAEKSHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KHRHSITNPLAVLCEFISQSIKSFDRHFEKNRNNALDFVTKSYNETKIKFDKYKAEKSHD 3190 3200 3210 3220 3230 3240 3250 3260 3270 3280 3290 3300 pF1KE0 ELPRTFQIPGYTVPVVNVEVSPFTIEMSAFGYVFPKAVSMPSFSILGSDVRVPSYTLILP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ELPRTFQIPGYTVPVVNVEVSPFTIEMSAFGYVFPKAVSMPSFSILGSDVRVPSYTLILP 3250 3260 3270 3280 3290 3300 3310 3320 3330 3340 3350 3360 pF1KE0 SLELPVLHVPRNLKLSLPDFKELCTISHIFIPAMGNITYDFSFKSSVITLNTNAELFNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SLELPVLHVPRNLKLSLPDFKELCTISHIFIPAMGNITYDFSFKSSVITLNTNAELFNQS 3310 3320 3330 3340 3350 3360 3370 3380 3390 3400 3410 3420 pF1KE0 DIVAHLLSSSSSVIDALQYKLEGTTRLTRKRGLKLATALSLSNKFVEGSHNSTVSLTTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DIVAHLLSSSSSVIDALQYKLEGTTRLTRKRGLKLATALSLSNKFVEGSHNSTVSLTTKN 3370 3380 3390 3400 3410 3420 3430 3440 3450 3460 3470 3480 pF1KE0 MEVSVATTTKAQIPILRMNFKQELNGNTKSKPTVSSSMEFKYDFNSSMLYSTAKGAVDHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MEVSVATTTKAQIPILRMNFKQELNGNTKSKPTVSSSMEFKYDFNSSMLYSTAKGAVDHK 3430 3440 3450 3460 3470 3480 3490 3500 3510 3520 3530 3540 pF1KE0 LSLESLTSYFSIESSTKGDVKGSVLSREYSGTIASEANTYLNSKSTRSSVKLQGTSKIDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LSLESLTSYFSIESSTKGDVKGSVLSREYSGTIASEANTYLNSKSTRSSVKLQGTSKIDD 3490 3500 3510 3520 3530 3540 3550 3560 3570 3580 3590 3600 pF1KE0 IWNLEVKENFAGEATLQRIYSLWEHSTKNHLQLEGLFFTNGEHTSKATLELSPWQMSALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IWNLEVKENFAGEATLQRIYSLWEHSTKNHLQLEGLFFTNGEHTSKATLELSPWQMSALV 3550 3560 3570 3580 3590 3600 3610 3620 3630 3640 3650 3660 pF1KE0 QVHASQPSSFHDFPDLGQEVALNANTKNQKIRWKNEVRIHSGSFQSQVELSNDQEKAHLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QVHASQPSSFHDFPDLGQEVALNANTKNQKIRWKNEVRIHSGSFQSQVELSNDQEKAHLD 3610 3620 3630 3640 3650 3660 3670 3680 3690 3700 3710 3720 pF1KE0 IAGSLEGHLRFLKNIILPVYDKSLWDFLKLDVTTSIGRRQHLRVSTAFVYTKNPNGYSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IAGSLEGHLRFLKNIILPVYDKSLWDFLKLDVTTSIGRRQHLRVSTAFVYTKNPNGYSFS 3670 3680 3690 3700 3710 3720 3730 3740 3750 3760 3770 3780 pF1KE0 IPVKVLADKFIIPGLKLNDLNSVLVMPTFHVPFTDLQVPSCKLDFREIQIYKKLRTSSFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IPVKVLADKFIIPGLKLNDLNSVLVMPTFHVPFTDLQVPSCKLDFREIQIYKKLRTSSFA 3730 3740 3750 3760 3770 3780 3790 3800 3810 3820 3830 3840 pF1KE0 LNLPTLPEVKFPEVDVLTKYSQPEDSLIPFFEITVPESQLTVSQFTLPKSVSDGIAALDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LNLPTLPEVKFPEVDVLTKYSQPEDSLIPFFEITVPESQLTVSQFTLPKSVSDGIAALDL 3790 3800 3810 3820 3830 3840 3850 3860 3870 3880 3890 3900 pF1KE0 NAVANKIADFELPTIIVPEQTIEIPSIKFSVPAGIVIPSFQALTARFEVDSPVYNATWSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NAVANKIADFELPTIIVPEQTIEIPSIKFSVPAGIVIPSFQALTARFEVDSPVYNATWSA 3850 3860 3870 3880 3890 3900 3910 3920 3930 3940 3950 3960 pF1KE0 SLKNKADYVETVLDSTCSSTVQFLEYELNVLGTHKIEDGTLASKTKGTFAHRDFSAEYEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SLKNKADYVETVLDSTCSSTVQFLEYELNVLGTHKIEDGTLASKTKGTFAHRDFSAEYEE 3910 3920 3930 3940 3950 3960 3970 3980 3990 4000 4010 4020 pF1KE0 DGKYEGLQEWEGKAHLNIKSPAFTDLHLRYQKDKKGISTSAASPAVGTVGMDMDEDDDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DGKYEGLQEWEGKAHLNIKSPAFTDLHLRYQKDKKGISTSAASPAVGTVGMDMDEDDDFS 3970 3980 3990 4000 4010 4020 4030 4040 4050 4060 4070 4080 pF1KE0 KWNFYYSPQSSPDKKLTIFKTELRVRESDEETQIKVNWEEEAASGLLTSLKDNVPKATGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KWNFYYSPQSSPDKKLTIFKTELRVRESDEETQIKVNWEEEAASGLLTSLKDNVPKATGV 4030 4040 4050 4060 4070 4080 4090 4100 4110 4120 4130 4140 pF1KE0 LYDYVNKYHWEHTGLTLREVSSKLRRNLQNNAEWVYQGAIRQIDDIDVRFQKAASGTTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LYDYVNKYHWEHTGLTLREVSSKLRRNLQNNAEWVYQGAIRQIDDIDVRFQKAASGTTGT 4090 4100 4110 4120 4130 4140 4150 4160 4170 4180 4190 4200 pF1KE0 YQEWKDKAQNLYQELLTQEGQASFQGLKDNVFDGLVRVTQEFHMKVKHLIDSLIDFLNFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YQEWKDKAQNLYQELLTQEGQASFQGLKDNVFDGLVRVTQEFHMKVKHLIDSLIDFLNFP 4150 4160 4170 4180 4190 4200 4210 4220 4230 4240 4250 4260 pF1KE0 RFQFPGKPGIYTREELCTMFIREVGTVLSQVYSKVHNGSEILFSYFQDLVITLPFELRKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RFQFPGKPGIYTREELCTMFIREVGTVLSQVYSKVHNGSEILFSYFQDLVITLPFELRKH 4210 4220 4230 4240 4250 4260 4270 4280 4290 4300 4310 4320 pF1KE0 KLIDVISMYRELLKDLSKEAQEVFKAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KLIDVISMYRELLKDLSKEAQEVFKAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEM 4270 4280 4290 4300 4310 4320 4330 4340 4350 4360 4370 4380 pF1KE0 KFTYLINYIQDEINTIFSDYIPYVFKLLKENLCLNLHKFNEFIQNELQEASQELQQIHQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KFTYLINYIQDEINTIFSDYIPYVFKLLKENLCLNLHKFNEFIQNELQEASQELQQIHQY 4330 4340 4350 4360 4370 4380 4390 4400 4410 4420 4430 4440 pF1KE0 IMALREEYFDPSIVGWTVKYYELEEKIVSLIKNLLVALKDFHSEYIVSASNFTSQLSSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IMALREEYFDPSIVGWTVKYYELEEKIVSLIKNLLVALKDFHSEYIVSASNFTSQLSSQV 4390 4400 4410 4420 4430 4440 4450 4460 4470 4480 4490 4500 pF1KE0 EQFLHRNIQEYLSILTDPDGKGKEKIAELSATAQEIIKSQTIATKKIISDYHQQFRYKLQ ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_000 EQFLHRNIQEYLSILTDPDGKGKEKIAELSATAQEIIKSQAIATKKIISDYHQQFRYKLQ 4450 4460 4470 4480 4490 4500 4510 4520 4530 4540 4550 4560 pF1KE0 DFSDQLSDYYEKFIAESKRLIDLSIQNYHTFLIYITELLKKLQSTTVMNPYMKLAPGELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DFSDQLSDYYEKFIAESKRLIDLSIQNYHTFLIYITELLKKLQSTTVMNPYMKLAPGELT 4510 4520 4530 4540 4550 4560 pF1KE0 IIL ::: NP_000 IIL >>XP_016882535 (OMIM: 145900,605725,614895) PREDICTED: p (1427 aa) initn: 312 init1: 82 opt: 227 Z-score: 228.4 bits: 56.5 E(85289): 5.6e-06 Smith-Waterman score: 227; 27.3% identity (62.6% similar) in 187 aa overlap (2587-2767:478-647) 2560 2570 2580 2590 2600 2610 pF1KE0 AAKNLTDFAEQYSIQDWAKRMKALVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPD :::.. : . ..:: . : : .:. XP_016 PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVR--LPEVQLLKVSEMKLPK----VPE 450 460 470 480 490 500 2620 2630 2640 2650 2660 2670 pF1KE0 FIVPLTDLRIPSVQINFKDLKNIKIP--SRFSTPEFTILNTFHIPSFT-IDFVEMKVKII . :: ..:.: ::. ....:.: :. ..:: : ..:. . :::. . XP_016 MAVP--EVRLPEVQL--PKVSEMKLPEVSEVAVPEVR-LPEVQLPKVPEMKVPEMKLPKV 510 520 530 540 550 2680 2690 2700 2710 2720 2730 pF1KE0 --RTIDQMLNSELQWP-VPDIYLRDLKVEDIPLARITLPDFRLPEIAIPEFIIPTLNLND . .: :.: : ::.. . :... .. : .. :...:::. .:: .: .. . XP_016 PEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKV--PEMKLPEMKLPEVKLP--KVPE 560 570 580 590 600 610 2740 2750 2760 2770 2780 2790 pF1KE0 FQVPDLHIPEFQLPHISHTIEVPTFGKLYSILKIQSPLFTLDANADIGNGTTSANEAGIA . :::.:.:: :::.. . ...: . .. .. ... : XP_016 MAVPDVHLPEVQLPKVPE-MKLPKMPEM-AVPEVRLPEVQLPKVSEMKLPKVPEMAVPDV 620 630 640 650 660 670 2800 2810 2820 2830 2840 2850 pF1KE0 ASITAKGESKLEVLNFDFQANAQLSNPKINPLALKESVKFSSKYLRTEHGSEMLFFGNAI XP_016 HLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVP 680 690 700 710 720 730 >>XP_016882536 (OMIM: 145900,605725,614895) PREDICTED: p (1427 aa) initn: 312 init1: 82 opt: 227 Z-score: 228.4 bits: 56.5 E(85289): 5.6e-06 Smith-Waterman score: 227; 27.3% identity (62.6% similar) in 187 aa overlap (2587-2767:478-647) 2560 2570 2580 2590 2600 2610 pF1KE0 AAKNLTDFAEQYSIQDWAKRMKALVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPD :::.. : . ..:: . : : .:. XP_016 PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVR--LPEVQLLKVSEMKLPK----VPE 450 460 470 480 490 500 2620 2630 2640 2650 2660 2670 pF1KE0 FIVPLTDLRIPSVQINFKDLKNIKIP--SRFSTPEFTILNTFHIPSFT-IDFVEMKVKII . :: ..:.: ::. ....:.: :. ..:: : ..:. . :::. . XP_016 MAVP--EVRLPEVQL--PKVSEMKLPEVSEVAVPEVR-LPEVQLPKVPEMKVPEMKLPKV 510 520 530 540 550 2680 2690 2700 2710 2720 2730 pF1KE0 --RTIDQMLNSELQWP-VPDIYLRDLKVEDIPLARITLPDFRLPEIAIPEFIIPTLNLND . .: :.: : ::.. . :... .. : .. :...:::. .:: .: .. . XP_016 PEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKV--PEMKLPEMKLPEVKLP--KVPE 560 570 580 590 600 610 2740 2750 2760 2770 2780 2790 pF1KE0 FQVPDLHIPEFQLPHISHTIEVPTFGKLYSILKIQSPLFTLDANADIGNGTTSANEAGIA . :::.:.:: :::.. . ...: . .. .. ... : XP_016 MAVPDVHLPEVQLPKVPE-MKLPKMPEM-AVPEVRLPEVQLPKVSEMKLPKVPEMAVPDV 620 630 640 650 660 670 2800 2810 2820 2830 2840 2850 pF1KE0 ASITAKGESKLEVLNFDFQANAQLSNPKINPLALKESVKFSSKYLRTEHGSEMLFFGNAI XP_016 HLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVP 680 690 700 710 720 730 >>NP_870998 (OMIM: 145900,605725,614895) periaxin isofor (1461 aa) initn: 312 init1: 82 opt: 227 Z-score: 228.2 bits: 56.5 E(85289): 5.7e-06 Smith-Waterman score: 227; 27.3% identity (62.6% similar) in 187 aa overlap (2587-2767:512-681) 2560 2570 2580 2590 2600 2610 pF1KE0 AAKNLTDFAEQYSIQDWAKRMKALVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPD :::.. : . ..:: . : : .:. NP_870 PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVR--LPEVQLLKVSEMKLPK----VPE 490 500 510 520 530 2620 2630 2640 2650 2660 2670 pF1KE0 FIVPLTDLRIPSVQINFKDLKNIKIP--SRFSTPEFTILNTFHIPSFT-IDFVEMKVKII . :: ..:.: ::. ....:.: :. ..:: : ..:. . :::. . NP_870 MAVP--EVRLPEVQL--PKVSEMKLPEVSEVAVPEVR-LPEVQLPKVPEMKVPEMKLPKV 540 550 560 570 580 590 2680 2690 2700 2710 2720 2730 pF1KE0 --RTIDQMLNSELQWP-VPDIYLRDLKVEDIPLARITLPDFRLPEIAIPEFIIPTLNLND . .: :.: : ::.. . :... .. : .. :...:::. .:: .: .. . NP_870 PEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKV--PEMKLPEMKLPEVKLP--KVPE 600 610 620 630 640 2740 2750 2760 2770 2780 2790 pF1KE0 FQVPDLHIPEFQLPHISHTIEVPTFGKLYSILKIQSPLFTLDANADIGNGTTSANEAGIA . :::.:.:: :::.. . ...: . .. .. ... : NP_870 MAVPDVHLPEVQLPKVPE-MKLPKMPEM-AVPEVRLPEVQLPKVSEMKLPKVPEMAVPDV 650 660 670 680 690 700 2800 2810 2820 2830 2840 2850 pF1KE0 ASITAKGESKLEVLNFDFQANAQLSNPKINPLALKESVKFSSKYLRTEHGSEMLFFGNAI NP_870 HLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVP 710 720 730 740 750 760 >>XP_011525473 (OMIM: 145900,605725,614895) PREDICTED: p (1461 aa) initn: 312 init1: 82 opt: 227 Z-score: 228.2 bits: 56.5 E(85289): 5.7e-06 Smith-Waterman score: 227; 27.3% identity (62.6% similar) in 187 aa overlap (2587-2767:512-681) 2560 2570 2580 2590 2600 2610 pF1KE0 AAKNLTDFAEQYSIQDWAKRMKALVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPD :::.. : . ..:: . : : .:. XP_011 PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVR--LPEVQLLKVSEMKLPK----VPE 490 500 510 520 530 2620 2630 2640 2650 2660 2670 pF1KE0 FIVPLTDLRIPSVQINFKDLKNIKIP--SRFSTPEFTILNTFHIPSFT-IDFVEMKVKII . :: ..:.: ::. ....:.: :. ..:: : ..:. . :::. . XP_011 MAVP--EVRLPEVQL--PKVSEMKLPEVSEVAVPEVR-LPEVQLPKVPEMKVPEMKLPKV 540 550 560 570 580 590 2680 2690 2700 2710 2720 2730 pF1KE0 --RTIDQMLNSELQWP-VPDIYLRDLKVEDIPLARITLPDFRLPEIAIPEFIIPTLNLND . .: :.: : ::.. . :... .. : .. :...:::. .:: .: .. . XP_011 PEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKV--PEMKLPEMKLPEVKLP--KVPE 600 610 620 630 640 2740 2750 2760 2770 2780 2790 pF1KE0 FQVPDLHIPEFQLPHISHTIEVPTFGKLYSILKIQSPLFTLDANADIGNGTTSANEAGIA . :::.:.:: :::.. . ...: . .. .. ... : XP_011 MAVPDVHLPEVQLPKVPE-MKLPKMPEM-AVPEVRLPEVQLPKVSEMKLPKVPEMAVPDV 650 660 670 680 690 700 2800 2810 2820 2830 2840 2850 pF1KE0 ASITAKGESKLEVLNFDFQANAQLSNPKINPLALKESVKFSSKYLRTEHGSEMLFFGNAI XP_011 HLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVP 710 720 730 740 750 760 4563 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 20:02:37 2016 done: Sun Nov 6 20:02:42 2016 Total Scan time: 33.450 Total Display time: 0.770 Function used was FASTA [36.3.4 Apr, 2011]