FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0702, 406 aa 1>>>pF1KE0702 406 - 406 aa - 406 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4010+/-0.00116; mu= 6.3907+/- 0.066 mean_var=245.0231+/-57.676, 0's: 0 Z-trim(109.6): 624 B-trim: 115 in 1/49 Lambda= 0.081935 statistics sampled from 10218 (10978) to 10218 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.337), width: 16 Scan time: 2.910 The best scores are: opt bits E(32554) CCDS10690.1 PHKG2 gene_id:5261|Hs108|chr16 ( 406) 2754 339.3 4e-93 CCDS54002.1 PHKG2 gene_id:5261|Hs108|chr16 ( 374) 2463 304.8 8.6e-83 CCDS5525.1 PHKG1 gene_id:5260|Hs108|chr7 ( 387) 1717 216.7 3.1e-56 CCDS59057.1 PHKG1 gene_id:5260|Hs108|chr7 ( 419) 1317 169.4 5.5e-42 CCDS34076.1 DCLK2 gene_id:166614|Hs108|chr4 ( 766) 650 90.9 4.3e-18 CCDS47142.2 DCLK2 gene_id:166614|Hs108|chr4 ( 783) 650 90.9 4.4e-18 CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 644 89.8 4.6e-18 CCDS43064.1 DCLK3 gene_id:85443|Hs108|chr3 ( 648) 641 89.8 8.2e-18 CCDS48094.1 CASK gene_id:8573|Hs108|chrX ( 897) 627 88.3 3.1e-17 CCDS48095.1 CASK gene_id:8573|Hs108|chrX ( 898) 627 88.3 3.1e-17 CCDS14257.1 CASK gene_id:8573|Hs108|chrX ( 921) 627 88.3 3.2e-17 CCDS82950.1 CAMK2D gene_id:817|Hs108|chr4 ( 498) 622 87.4 3.3e-17 CCDS73561.1 DCLK1 gene_id:9201|Hs108|chr13 ( 422) 620 87.0 3.5e-17 CCDS55895.1 DCLK1 gene_id:9201|Hs108|chr13 ( 433) 620 87.0 3.6e-17 CCDS3704.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 620 87.1 3.8e-17 CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 620 87.1 3.8e-17 CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 ( 489) 620 87.1 3.9e-17 CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 ( 492) 620 87.1 3.9e-17 CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 ( 495) 620 87.1 3.9e-17 CCDS3703.1 CAMK2D gene_id:817|Hs108|chr4 ( 499) 620 87.1 3.9e-17 CCDS7337.1 CAMK2G gene_id:818|Hs108|chr10 ( 527) 620 87.2 4e-17 CCDS73153.1 CAMK2G gene_id:818|Hs108|chr10 ( 539) 620 87.2 4.1e-17 CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 617 86.6 4.2e-17 CCDS7338.1 CAMK2G gene_id:818|Hs108|chr10 ( 556) 620 87.2 4.2e-17 CCDS9354.1 DCLK1 gene_id:9201|Hs108|chr13 ( 729) 620 87.3 4.9e-17 CCDS81762.1 DCLK1 gene_id:9201|Hs108|chr13 ( 740) 620 87.4 5e-17 CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 ( 512) 611 86.1 8.3e-17 CCDS82949.1 CAMK2D gene_id:817|Hs108|chr4 ( 533) 611 86.1 8.5e-17 CCDS48189.1 PNCK gene_id:139728|Hs108|chrX ( 360) 608 85.5 8.6e-17 CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 ( 473) 610 85.9 8.6e-17 CCDS35503.2 PNCK gene_id:139728|Hs108|chrX ( 426) 608 85.6 9.5e-17 CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 608 85.7 9.8e-17 CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 605 85.2 1.1e-16 CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 605 85.2 1.1e-16 CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 ( 476) 606 85.4 1.2e-16 CCDS43386.1 CAMK2A gene_id:815|Hs108|chr5 ( 478) 605 85.3 1.3e-16 CCDS43387.1 CAMK2A gene_id:815|Hs108|chr5 ( 489) 605 85.3 1.3e-16 CCDS13843.1 CHEK2 gene_id:11200|Hs108|chr22 ( 543) 597 84.5 2.7e-16 CCDS33629.1 CHEK2 gene_id:11200|Hs108|chr22 ( 586) 597 84.5 2.8e-16 CCDS5489.1 CAMK2B gene_id:816|Hs108|chr7 ( 449) 593 83.9 3.3e-16 CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 ( 479) 592 83.8 3.8e-16 CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 ( 492) 592 83.8 3.8e-16 CCDS5486.1 CAMK2B gene_id:816|Hs108|chr7 ( 503) 592 83.8 3.9e-16 CCDS43573.1 CAMK2B gene_id:816|Hs108|chr7 ( 517) 592 83.8 4e-16 CCDS5485.1 CAMK2B gene_id:816|Hs108|chr7 ( 518) 592 83.8 4e-16 CCDS5484.1 CAMK2B gene_id:816|Hs108|chr7 ( 542) 592 83.9 4.1e-16 CCDS5483.1 CAMK2B gene_id:816|Hs108|chr7 ( 666) 592 84.0 4.6e-16 CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 580 82.3 9.4e-16 CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 585 83.6 1.3e-15 CCDS2832.1 MAPKAPK3 gene_id:7867|Hs108|chr3 ( 382) 560 79.9 4.5e-15 >>CCDS10690.1 PHKG2 gene_id:5261|Hs108|chr16 (406 aa) initn: 2754 init1: 2754 opt: 2754 Z-score: 1785.4 bits: 339.3 E(32554): 4e-93 Smith-Waterman score: 2754; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406) 10 20 30 40 50 60 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH 310 320 330 340 350 360 370 380 390 400 pF1KE0 WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG :::::::::::::::::::::::::::::::::::::::::::::: CCDS10 WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG 370 380 390 400 >>CCDS54002.1 PHKG2 gene_id:5261|Hs108|chr16 (374 aa) initn: 2463 init1: 2463 opt: 2463 Z-score: 1599.9 bits: 304.8 E(32554): 8.6e-83 Smith-Waterman score: 2463; 99.5% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH 310 320 330 340 350 360 370 380 390 400 pF1KE0 WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG :..: CCDS54 WIRKQWIGKLMACV 370 >>CCDS5525.1 PHKG1 gene_id:5260|Hs108|chr7 (387 aa) initn: 1718 init1: 1509 opt: 1717 Z-score: 1123.1 bits: 216.7 E(32554): 3.1e-56 Smith-Waterman score: 1717; 64.5% identity (89.0% similar) in 372 aa overlap (8-378:4-375) 10 20 30 40 50 60 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE .. ::: .:..::..:.::...:::::::::::.:. :..:.:::...::. CCDS55 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG 10 20 30 40 50 70 80 90 100 110 pF1KE0 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL .:::...:.:::: .:. :::.:.:::.:: : :.::...:.:::::::..::::::: CCDS55 GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE ::::.:::::::.:::.:::.. :: ::::::::::::::::::.:.:.::::::.:: CCDS55 TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 PGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQI :::.:::.::::.::::::..:::.: :::::::::.:. :::..::::::::::::.:. CCDS55 PGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 LMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQP ::::::: :.:::.:::::: :.:::::.::.: :.:. : :::.:: ::::.. . CCDS55 LMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 WNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYG ...:: .:.: . ::::. :. . .::.:.:.. ..::::::: .:.::: :::.:: CCDS55 RHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYG 300 310 320 330 340 350 360 370 380 390 400 pF1KE0 HWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG ::::::.::::::::.. : CCDS55 HWVKKGQQQNRAALFENTPKAVLLSLAEEDY 360 370 380 >>CCDS59057.1 PHKG1 gene_id:5260|Hs108|chr7 (419 aa) initn: 1713 init1: 1317 opt: 1317 Z-score: 867.2 bits: 169.4 E(32554): 5.5e-42 Smith-Waterman score: 1643; 59.4% identity (81.9% similar) in 404 aa overlap (8-378:4-407) 10 20 30 40 50 60 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE .. ::: .:..::..:.::...:::::::::::.:. :..:.:::...::. CCDS59 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG 10 20 30 40 50 70 80 90 100 pF1KE0 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDL---------- .:::...:.:::: .:. :::.:.:::.:: : :.::...:.:::::: CCDS59 GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLWEDTDTMEME 60 70 80 90 100 110 110 120 130 140 pF1KE0 ----------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHAN :..:::::::::::.:::::::.:::.:::.. :: CCDS59 QKWCLGWDSPKSTNFRAQGRARMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKL 120 130 140 150 160 170 150 160 170 180 190 200 pF1KE0 NIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETH ::::::::::::::::::.:.:.::::::.:::::.:::.::::.::::::..:::.: : CCDS59 NIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDH 180 190 200 210 220 230 210 220 230 240 250 260 pF1KE0 PGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDL ::::::::.:. :::..::::::::::::.:.::::::: :.:::.:::::: :.::::: CCDS59 PGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDL 240 250 260 270 280 290 270 280 290 300 310 320 pF1KE0 ISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHR .::.: :.:. : :::.:: ::::.. . ...:: .:.: . ::::. :. . .: CCDS59 VSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRR 300 310 320 330 340 350 330 340 350 360 370 380 pF1KE0 VRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGP :.:.:.. ..::::::: .:.::: :::.::::::::.::::::::.. : CCDS59 VKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAE 360 370 380 390 400 410 390 400 pF1KE0 EEEGDSAAITEDEAVLVLG CCDS59 EDY >>CCDS34076.1 DCLK2 gene_id:166614|Hs108|chr4 (766 aa) initn: 592 init1: 223 opt: 650 Z-score: 438.2 bits: 90.9 E(32554): 4.3e-18 Smith-Waterman score: 650; 40.4% identity (69.7% similar) in 287 aa overlap (22-302:392-661) 10 20 30 40 50 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFA .:: ::: : .::..:. :.::.::: CCDS34 SNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFA 370 380 390 400 410 420 60 70 80 90 100 110 pF1KE0 VKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMR .::.. :. . :.: : :. :::.: ::.:: :.. .:... .:::..:.. CCDS34 LKIID-KAKCCGKEHLIE------NEVSILRRVK-HPNIIMLVEEMETATELFLVMELVK 430 440 450 460 470 120 130 140 150 160 pF1KE0 KGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL----DDNMQI :.::: .: .. .:.. ... .: .:. .::. .:::::.::::.:. : . .. CCDS34 GGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSL 480 490 500 510 520 530 170 180 190 200 210 220 pF1KE0 RLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLL .:.:::.. .: : : .:::: :.::::. :: ::: .::.:: ::: . :: CCDS34 KLGDFGLATVVE-GP-LYTVCGTPTYVAPEIIA----ET--GYGLKVDIWAAGVITYILL 540 550 560 570 580 230 240 250 260 270 280 pF1KE0 AGSPPFWHRRQIL--MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQA : ::: . .. .. .:. :. .: .: ::. ....:.:::..:::. ::: :: : CCDS34 CGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQI 590 600 610 620 630 640 290 300 310 320 330 340 pF1KE0 LQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRS :.::. ..:: :. CCDS34 LSHPWVSD-DASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCS 650 660 670 680 690 700 >>CCDS47142.2 DCLK2 gene_id:166614|Hs108|chr4 (783 aa) initn: 592 init1: 223 opt: 650 Z-score: 438.1 bits: 90.9 E(32554): 4.4e-18 Smith-Waterman score: 650; 40.4% identity (69.7% similar) in 287 aa overlap (22-302:409-678) 10 20 30 40 50 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFA .:: ::: : .::..:. :.::.::: CCDS47 SNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFA 380 390 400 410 420 430 60 70 80 90 100 110 pF1KE0 VKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMR .::.. :. . :.: : :. :::.: ::.:: :.. .:... .:::..:.. CCDS47 LKIID-KAKCCGKEHLIE------NEVSILRRVK-HPNIIMLVEEMETATELFLVMELVK 440 450 460 470 480 490 120 130 140 150 160 pF1KE0 KGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL----DDNMQI :.::: .: .. .:.. ... .: .:. .::. .:::::.::::.:. : . .. CCDS47 GGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSL 500 510 520 530 540 550 170 180 190 200 210 220 pF1KE0 RLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLL .:.:::.. .: : : .:::: :.::::. :: ::: .::.:: ::: . :: CCDS47 KLGDFGLATVVE-GP-LYTVCGTPTYVAPEIIA----ET--GYGLKVDIWAAGVITYILL 560 570 580 590 600 230 240 250 260 270 280 pF1KE0 AGSPPFWHRRQIL--MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQA : ::: . .. .. .:. :. .: .: ::. ....:.:::..:::. ::: :: : CCDS47 CGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQI 610 620 630 640 650 660 290 300 310 320 330 340 pF1KE0 LQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRS :.::. ..:: :. CCDS47 LSHPWVSD-DASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCS 670 680 690 700 710 720 >>CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 (370 aa) initn: 677 init1: 288 opt: 644 Z-score: 437.9 bits: 89.8 E(32554): 4.6e-18 Smith-Waterman score: 696; 40.5% identity (68.3% similar) in 284 aa overlap (10-290:6-275) 10 20 30 40 50 60 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE : : : :... . :: .::.: :. : : . : . :.: CCDS25 MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKC------ 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT .. : :: . . . : .:... ::.:..: : :::.. ..:...:. ::::: .. CCDS25 -IAKEALEGKEGSMENEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIV 60 70 80 90 100 130 140 150 160 170 pF1KE0 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENIL---LDDNMQIRLSDFGFSCH :: .:... .. ..:.::..:: .::::::::::.: ::.. .: .::::.: CCDS25 EKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKM 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 LEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRR .:: : ::::::.:::.: .: :.: :: :. ::: . :: : :::. . CCDS25 EDPGSVLSTACGTPGYVAPEVLA-----QKP-YSKAVDCWSIGVIAYILLCGYPPFYDEN 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 QILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGS . ....:....:.:.:: ::: :...::.: .:.. ::: :.: :::::::. CCDS25 DAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTAL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 QPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRL CCDS25 DKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTASHGELLTPVA 290 300 310 320 330 340 >>CCDS43064.1 DCLK3 gene_id:85443|Hs108|chr3 (648 aa) initn: 625 init1: 203 opt: 641 Z-score: 433.3 bits: 89.8 E(32554): 8.2e-18 Smith-Waterman score: 641; 37.4% identity (66.2% similar) in 302 aa overlap (12-307:344-626) 10 20 30 40 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRC : : . ..:. ::: : .::..: CCDS43 RDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKEC 320 330 340 350 360 370 50 60 70 80 90 100 pF1KE0 VHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSS :: : . .:.::.. . ::. .. . . : :..... ::.:. : . ::.. CCDS43 RHRETRQAYAMKIIDKS--RLKGKE-----DMVDSEILIIQSLS-HPNIVKLHEVYETDM 380 390 400 410 420 110 120 130 140 150 160 pF1KE0 FMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL ..:... .. :.::: . :.: . : .. .. .: .:. .: ..::::::::::.:. CCDS43 EIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLV 430 440 450 460 470 480 170 180 190 200 210 pF1KE0 ----DDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLW : . ..:.:::.. :. . . .:::: :.::::: .. ::: :::.: CCDS43 QRNEDKSTTLKLADFGLAKHVV--RPIFTVCGTPTYVAPEIL------SEKGYGLEVDMW 490 500 510 520 530 220 230 240 250 260 270 pF1KE0 ACGVILFTLLAGSPPFW--HRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVD : ::::. :: : ::: .: : .. .:. :...: : ::. :...:::.:::: :: CCDS43 AAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVD 540 550 560 570 580 590 280 290 300 310 320 330 pF1KE0 PEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNA :. : ::.:.::::..: . : . ::. CCDS43 PKKRYTAHQVLQHPWIETAGKT---NTVKRQKQVSPSSEGHFRSQHKRVVEQVS 600 610 620 630 640 340 350 360 370 380 390 pF1KE0 LLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAA >>CCDS48094.1 CASK gene_id:8573|Hs108|chrX (897 aa) initn: 455 init1: 205 opt: 627 Z-score: 422.8 bits: 88.3 E(32554): 3.1e-17 Smith-Waterman score: 627; 38.4% identity (68.3% similar) in 281 aa overlap (20-292:8-277) 10 20 30 40 50 60 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE : . :. .:::.: ::::::..: ::..:::::..:. CCDS48 MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKF 10 20 30 40 70 80 90 100 110 pF1KE0 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGEL-FDYL :: : .::. : ... ::::. :...: :......::..: ..: :. . CCDS48 TSSPGL---STEDLKREASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIV 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 TEKVA---LSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL---DDNMQIRLSDFG . : :: . ::..:::. . : :::.:::.::. .:: ... ..:. :: CCDS48 KRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 FSCHL-EPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPP . .: : : ::: ..:::..: .: ::: ::.:.:::::: ::.: : CCDS48 VAIQLGESGLVAGGRVGTPHFMAPEVVK-----REP-YGKPVDVWGCGVILFILLSGCLP 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 FWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFE :. .. : .. :..:.:... .:. : ..:::. :.:..:: :.:. .::.::... CCDS48 FYGTKERL-FEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLK 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 RCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDN CCDS48 ERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTS 280 290 300 310 320 330 >>CCDS48095.1 CASK gene_id:8573|Hs108|chrX (898 aa) initn: 455 init1: 205 opt: 627 Z-score: 422.8 bits: 88.3 E(32554): 3.1e-17 Smith-Waterman score: 627; 38.4% identity (68.3% similar) in 281 aa overlap (20-292:8-277) 10 20 30 40 50 60 pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE : . :. .:::.: ::::::..: ::..:::::..:. CCDS48 MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKF 10 20 30 40 70 80 90 100 110 pF1KE0 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGEL-FDYL :: : .::. : ... ::::. :...: :......::..: ..: :. . CCDS48 TSSPGL---STEDLKREASICHMLK-HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIV 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 TEKVA---LSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL---DDNMQIRLSDFG . : :: . ::..:::. . : :::.:::.::. .:: ... ..:. :: CCDS48 KRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 FSCHL-EPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPP . .: : : ::: ..:::..: .: ::: ::.:.:::::: ::.: : CCDS48 VAIQLGESGLVAGGRVGTPHFMAPEVVK-----REP-YGKPVDVWGCGVILFILLSGCLP 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 FWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFE :. .. : .. :..:.:... .:. : ..:::. :.:..:: :.:. .::.::... CCDS48 FYGTKERL-FEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLK 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 RCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDN CCDS48 ERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTS 280 290 300 310 320 330 406 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:51:18 2016 done: Sat Nov 5 02:51:19 2016 Total Scan time: 2.910 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]