FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0705, 295 aa
1>>>pF1KE0705 295 - 295 aa - 295 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4290+/-0.000377; mu= 12.9983+/- 0.024
mean_var=198.2682+/-43.660, 0's: 0 Z-trim(118.8): 196 B-trim: 1878 in 1/57
Lambda= 0.091085
statistics sampled from 31937 (32178) to 31937 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.377), width: 16
Scan time: 7.600
The best scores are: opt bits E(85289)
NP_001342 (OMIM: 601486) deleted in azoospermia-li ( 295) 2013 276.7 3.9e-74
NP_001177740 (OMIM: 601486) deleted in azoospermia ( 315) 2006 275.8 7.6e-74
NP_001005786 (OMIM: 400026,415000) deleted in azoo ( 366) 1077 153.8 4.7e-37
NP_065097 (OMIM: 400027,415000) deleted in azoospe ( 438) 1077 153.9 5.2e-37
NP_001005785 (OMIM: 400026,415000) deleted in azoo ( 534) 1077 154.0 5.8e-37
NP_065096 (OMIM: 400026,415000) deleted in azoospe ( 558) 1077 154.0 6e-37
XP_011529785 (OMIM: 400003,415000) PREDICTED: dele ( 529) 1070 153.1 1.1e-36
XP_011529784 (OMIM: 400003,415000) PREDICTED: dele ( 694) 1070 153.3 1.3e-36
NP_004072 (OMIM: 400003,415000) deleted in azoospe ( 744) 1070 153.3 1.3e-36
NP_149019 (OMIM: 606165) protein boule-like isofor ( 283) 400 64.7 2.4e-10
NP_001271291 (OMIM: 606165) protein boule-like iso ( 289) 400 64.7 2.4e-10
NP_932074 (OMIM: 606165) protein boule-like isofor ( 295) 400 64.7 2.5e-10
XP_006712778 (OMIM: 606165) PREDICTED: protein bou ( 291) 396 64.2 3.5e-10
XP_016860262 (OMIM: 606165) PREDICTED: protein bou ( 220) 375 61.2 2e-09
XP_011509996 (OMIM: 606165) PREDICTED: protein bou ( 305) 375 61.4 2.5e-09
XP_011509995 (OMIM: 606165) PREDICTED: protein bou ( 313) 375 61.4 2.5e-09
XP_011509994 (OMIM: 606165) PREDICTED: protein bou ( 317) 375 61.5 2.5e-09
NP_001271290 (OMIM: 606165) protein boule-like iso ( 339) 375 61.5 2.6e-09
>>NP_001342 (OMIM: 601486) deleted in azoospermia-like i (295 aa)
initn: 2013 init1: 2013 opt: 2013 Z-score: 1452.0 bits: 276.7 E(85289): 3.9e-74
Smith-Waterman score: 2013; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 NGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDKRVHHFRRSRAMLKSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDKRVHHFRRSRAMLKSV
250 260 270 280 290
>>NP_001177740 (OMIM: 601486) deleted in azoospermia-lik (315 aa)
initn: 2006 init1: 2006 opt: 2006 Z-score: 1446.7 bits: 275.8 E(85289): 7.6e-74
Smith-Waterman score: 2006; 100.0% identity (100.0% similar) in 294 aa overlap (2-295:22-315)
10 20 30 40
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPN
:::::::::::::::::::::::::::::::::::::::
NP_001 MAAPSCGGDRKARLTPSLPHESTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 INFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 ITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 PGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDK
250 260 270 280 290 300
290
pF1KE0 RVHHFRRSRAMLKSV
:::::::::::::::
NP_001 RVHHFRRSRAMLKSV
310
>>NP_001005786 (OMIM: 400026,415000) deleted in azoosper (366 aa)
initn: 1061 init1: 1061 opt: 1077 Z-score: 786.3 bits: 153.8 E(85289): 4.7e-37
Smith-Waterman score: 1077; 82.7% identity (90.8% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
::.::::::::::::::::::::::.:::..::::::.::::::::::.::::::: : :
NP_001 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
.::::::::::::.::::::::::::: ::::::::: :::.:::::::::::::::.::
NP_001 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
: :::::::: : :::::::::: :::::::.:: : ::.::.:::: .::.:: ::::
NP_001 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
: :: ::::: : .:
NP_001 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
>>NP_065097 (OMIM: 400027,415000) deleted in azoospermia (438 aa)
initn: 1061 init1: 1061 opt: 1077 Z-score: 785.5 bits: 153.9 E(85289): 5.2e-37
Smith-Waterman score: 1077; 82.7% identity (90.8% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
::.::::::::::::::::::::::.:::..::::::.::::::::::.::::::: : :
NP_065 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
.::::::::::::.::::::::::::: ::::::::: :::.:::::::::::::::.::
NP_065 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
: :::::::: : :::::::::: :::::::.:: : ::.::.:::: .::.:: ::::
NP_065 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
: :: ::::: : .:
NP_065 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
>>NP_001005785 (OMIM: 400026,415000) deleted in azoosper (534 aa)
initn: 1061 init1: 1061 opt: 1077 Z-score: 784.6 bits: 154.0 E(85289): 5.8e-37
Smith-Waterman score: 1077; 82.7% identity (90.8% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
::.::::::::::::::::::::::.:::..::::::.::::::::::.::::::: : :
NP_001 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
.::::::::::::.::::::::::::: ::::::::: :::.:::::::::::::::.::
NP_001 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
: :::::::: : :::::::::: :::::::.:: : ::.::.:::: .::.:: ::::
NP_001 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
: :: ::::: : .:
NP_001 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
>>NP_065096 (OMIM: 400026,415000) deleted in azoospermia (558 aa)
initn: 1061 init1: 1061 opt: 1077 Z-score: 784.4 bits: 154.0 E(85289): 6e-37
Smith-Waterman score: 1077; 82.7% identity (90.8% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
::.::::::::::::::::::::::.:::..::::::.::::::::::.::::::: : :
NP_065 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
.::::::::::::.::::::::::::: ::::::::: :::.:::::::::::::::.::
NP_065 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
: :::::::: : :::::::::: :::::::.:: : ::.::.:::: .::.:: ::::
NP_065 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
: :: ::::: : .:
NP_065 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
>>XP_011529785 (OMIM: 400003,415000) PREDICTED: deleted (529 aa)
initn: 1054 init1: 1054 opt: 1070 Z-score: 779.6 bits: 153.1 E(85289): 1.1e-36
Smith-Waterman score: 1070; 82.6% identity (90.8% similar) in 195 aa overlap (2-196:117-311)
10 20 30
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYI
:.::::::::::::::::::::::.:::..
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE0 LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDV
::::::.::::::::::.::::::: : :.::::::::::::.::::::::::::: :::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE0 DVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETY
:::::: :::.:::::::::::::::.::: :::::::: : :::::::::: :::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE0 MQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSA
.:: : ::.::.:::: .::.:: ::::: :: ::::: : .:
XP_011 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE0 VNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVV
XP_011 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
330 340 350 360 370 380
>--
initn: 664 init1: 664 opt: 664 Z-score: 491.3 bits: 99.7 E(85289): 1.3e-20
Smith-Waterman score: 664; 84.5% identity (90.5% similar) in 116 aa overlap (51-166:1-116)
30 40 50 60 70 80
pF1KE0 SSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSK
:::::: : :.::::::::::::.::::::
XP_011 MDETEIGSCFGRYGSVKEVKIITNRTGVSK
10 20 30
90 100 110 120 130 140
pF1KE0 GYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQ
::::::: ::::::::: :::.:::::::::::::::.::: :::::::: : :::::::
XP_011 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 NVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQ
::: :::::::.:: : ::.::.::
XP_011 NVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEG
100 110 120 130 140 150
>>XP_011529784 (OMIM: 400003,415000) PREDICTED: deleted (694 aa)
initn: 1589 init1: 1054 opt: 1070 Z-score: 778.4 bits: 153.3 E(85289): 1.3e-36
Smith-Waterman score: 1070; 82.6% identity (90.8% similar) in 195 aa overlap (2-196:282-476)
10 20 30
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYI
:.::::::::::::::::::::::.:::..
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
260 270 280 290 300 310
40 50 60 70 80 90
pF1KE0 LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDV
::::::.::::::::::.::::::: : :.::::::::::::.::::::::::::: :::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
320 330 340 350 360 370
100 110 120 130 140 150
pF1KE0 DVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETY
:::::: :::.:::::::::::::::.::: :::::::: : :::::::::: :::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
380 390 400 410 420 430
160 170 180 190 200 210
pF1KE0 MQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSA
.:: : ::.::.:::: .::.:: ::::: :: ::::: : .:
XP_011 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
440 450 460 470 480 490
220 230 240 250 260 270
pF1KE0 VNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVV
XP_011 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
500 510 520 530 540 550
>--
initn: 942 init1: 942 opt: 942 Z-score: 687.5 bits: 136.4 E(85289): 1.5e-31
Smith-Waterman score: 942; 85.5% identity (93.3% similar) in 165 aa overlap (2-166:117-281)
10 20 30
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYI
:.::::::::::::::::::::::.:::..
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE0 LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDV
::::::.::::::::::.::::::: : :.::::::::::::.::::::::::::: :::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE0 DVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETY
:::::: :::.:::::::::::::::.::: :::::::: : :::::::::: :::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE0 MQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSA
.:: : ::.::.::
XP_011 LQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGG
270 280 290 300 310 320
>--
initn: 664 init1: 664 opt: 664 Z-score: 490.1 bits: 99.9 E(85289): 1.5e-20
Smith-Waterman score: 664; 84.5% identity (90.5% similar) in 116 aa overlap (51-166:1-116)
30 40 50 60 70 80
pF1KE0 SSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSK
:::::: : :.::::::::::::.::::::
XP_011 MDETEIGSCFGRYGSVKEVKIITNRTGVSK
10 20 30
90 100 110 120 130 140
pF1KE0 GYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQ
::::::: ::::::::: :::.:::::::::::::::.::: :::::::: : :::::::
XP_011 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 NVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQ
::: :::::::.:: : ::.::.::
XP_011 NVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEG
100 110 120 130 140 150
>>NP_004072 (OMIM: 400003,415000) deleted in azoospermia (744 aa)
initn: 1874 init1: 1054 opt: 1070 Z-score: 778.1 bits: 153.3 E(85289): 1.3e-36
Smith-Waterman score: 1070; 82.6% identity (90.8% similar) in 195 aa overlap (2-196:332-526)
10 20 30
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYI
:.::::::::::::::::::::::.:::..
NP_004 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
310 320 330 340 350 360
40 50 60 70 80 90
pF1KE0 LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDV
::::::.::::::::::.::::::: : :.::::::::::::.::::::::::::: :::
NP_004 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
370 380 390 400 410 420
100 110 120 130 140 150
pF1KE0 DVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETY
:::::: :::.:::::::::::::::.::: :::::::: : :::::::::: :::::::
NP_004 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
430 440 450 460 470 480
160 170 180 190 200 210
pF1KE0 MQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSA
.:: : ::.::.:::: .::.:: ::::: :: ::::: : .:
NP_004 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
490 500 510 520 530 540
220 230 240 250 260 270
pF1KE0 VNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVV
NP_004 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
550 560 570 580 590 600
>--
initn: 991 init1: 950 opt: 970 Z-score: 707.1 bits: 140.2 E(85289): 1.2e-32
Smith-Waterman score: 970; 82.6% identity (90.4% similar) in 178 aa overlap (1-176:1-178)
10 20 30 40 50 60
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
::.::::::::::::::::::::::.:::..::::::.::::::::::.::::::: : :
NP_004 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
.::::::::::::.::::::::::::: ::::::::: :::.:::::::::::::::.::
NP_004 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQ--AYPTYPNSPVQV
: :::::::: : :::::::::: :::::::.:: : ::.::.:: : : ::: .
NP_004 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 ITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPP
NP_004 EASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNR
190 200 210 220 230 240
>--
initn: 872 init1: 872 opt: 872 Z-score: 637.5 bits: 127.3 E(85289): 9.1e-29
Smith-Waterman score: 872; 85.0% identity (92.8% similar) in 153 aa overlap (14-166:179-331)
10 20 30 40
pF1KE0 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVF
::::::::::::.:::..::::::.:::::
NP_004 ETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVF
150 160 170 180 190 200
50 60 70 80 90 100
pF1KE0 VGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINF
:::::.::::::: : :.::::::::::::.::::::::::::: ::::::::: :::.:
NP_004 VGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHF
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE0 HGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQ
::::::::::::::.::: :::::::: : :::::::::: :::::::.:: : ::.::
NP_004 HGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQ
270 280 290 300 310 320
170 180 190 200 210 220
pF1KE0 YVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGA
.::
NP_004 HVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGS
330 340 350 360 370 380
>>NP_149019 (OMIM: 606165) protein boule-like isoform 2 (283 aa)
initn: 319 init1: 288 opt: 400 Z-score: 306.7 bits: 64.7 E(85289): 2.4e-10
Smith-Waterman score: 416; 33.6% identity (59.3% similar) in 268 aa overlap (35-285:28-283)
10 20 30 40 50 60
pF1KE0 NPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYG
: ..:: .:::::: . .:...:.::..::
NP_149 MQTDSLSPSPNPVSPVPLNNPTSAPRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYG
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVES--QINFHGKKLKLGPAIRKQNLCAY
:::::::..::.:::::::::.: .. :.:::.. ..:.. :::..:::::::..
NP_149 SVKEVKIVNDRAGVSKGYGFVTFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGI-
60 70 80 90 100 110
130 140 150 160 170
pF1KE0 HVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMN-P-ITQYVQAYPTYP--NSPVQV
:: .. : . . .. :: . .. .. : .:. .:. .:::.:
NP_149 ---PRSSIM--PAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPPWPSRSVCSSPVMV
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 ITG-YQLPVYNYQ-----MPPQWP--VGEQRSYVVPPAY---SAVNYHCNEVDPGAEVVP
:: :.:.:: .: :: : . . .: : : : :. :. . ::
NP_149 AQPIYQQPAYHYQATTQYLPGQWQWSVPQPSASSAPFLYLQPSEVIYQPVEIAQDGGCVP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 NECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDKRVHHFRR
:. :.. : : . :...:.. .. : . : : . .: :.
NP_149 PPLSLMETSVPE---PYS---DHGVQATYHQVYAPSAITMPAPVMQPEPIKTVWSIHY
240 250 260 270 280
290
pF1KE0 SRAMLKSV
295 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:52:35 2016 done: Sat Nov 5 02:52:36 2016
Total Scan time: 7.600 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]