FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0708, 407 aa 1>>>pF1KE0708 407 - 407 aa - 407 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6351+/-0.00172; mu= 18.0057+/- 0.103 mean_var=266.3735+/-47.260, 0's: 0 Z-trim(107.4): 937 B-trim: 0 in 0/53 Lambda= 0.078583 statistics sampled from 8523 (9573) to 8523 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.294), width: 16 Scan time: 2.940 The best scores are: opt bits E(32554) CCDS12963.1 ZNF552 gene_id:79818|Hs108|chr19 ( 407) 2871 339.5 3.3e-93 CCDS46212.1 ZNF814 gene_id:730051|Hs108|chr19 ( 855) 2107 253.5 5.4e-67 CCDS56109.1 ZNF587B gene_id:100293516|Hs108|chr19 ( 402) 2010 241.9 8e-64 CCDS82410.1 ZNF418 gene_id:147686|Hs108|chr19 ( 697) 1907 230.7 3.3e-60 CCDS42642.1 ZNF418 gene_id:147686|Hs108|chr19 ( 676) 1903 230.2 4.5e-60 CCDS56110.1 ZNF587 gene_id:84914|Hs108|chr19 ( 574) 1592 194.8 1.7e-49 CCDS74469.1 ZNF417 gene_id:147687|Hs108|chr19 ( 574) 1587 194.3 2.5e-49 CCDS12962.2 ZNF776 gene_id:284309|Hs108|chr19 ( 518) 1585 193.9 2.8e-49 CCDS12966.1 ZNF256 gene_id:10172|Hs108|chr19 ( 627) 1497 184.1 3.1e-46 CCDS82409.1 ZNF418 gene_id:147686|Hs108|chr19 ( 591) 1455 179.3 8.2e-45 CCDS12957.1 ZNF211 gene_id:10520|Hs108|chr19 ( 564) 1441 177.7 2.4e-44 CCDS12956.1 ZNF211 gene_id:10520|Hs108|chr19 ( 577) 1421 175.4 1.2e-43 CCDS46210.1 ZNF772 gene_id:400720|Hs108|chr19 ( 448) 1400 172.9 5.5e-43 CCDS12955.1 ZNF530 gene_id:348327|Hs108|chr19 ( 599) 1295 161.2 2.4e-39 CCDS58688.1 ZNF211 gene_id:10520|Hs108|chr19 ( 503) 1271 158.3 1.5e-38 CCDS58687.1 ZNF211 gene_id:10520|Hs108|chr19 ( 555) 1233 154.1 3e-37 CCDS74468.1 ZNF211 gene_id:10520|Hs108|chr19 ( 616) 1233 154.2 3.2e-37 CCDS58686.1 ZNF211 gene_id:10520|Hs108|chr19 ( 629) 1233 154.2 3.2e-37 CCDS33133.1 ZNF772 gene_id:400720|Hs108|chr19 ( 489) 1188 148.9 9.8e-36 CCDS42638.1 ZNF134 gene_id:7693|Hs108|chr19 ( 427) 1148 144.2 2.1e-34 CCDS82406.1 ZNF772 gene_id:400720|Hs108|chr19 ( 377) 1146 143.9 2.4e-34 CCDS12980.1 ZNF132 gene_id:7691|Hs108|chr19 ( 706) 1140 143.7 5e-34 CCDS12961.1 ZNF671 gene_id:79891|Hs108|chr19 ( 534) 1074 136.0 7.9e-32 CCDS42639.1 ZNF154 gene_id:7710|Hs108|chr19 ( 437) 1023 130.1 4e-30 CCDS54325.1 ZNF419 gene_id:79744|Hs108|chr19 ( 511) 975 124.8 1.9e-28 CCDS77368.1 ZNF773 gene_id:374928|Hs108|chr19 ( 441) 969 124.0 2.8e-28 CCDS33134.1 ZNF773 gene_id:374928|Hs108|chr19 ( 442) 969 124.0 2.8e-28 CCDS54328.1 ZNF419 gene_id:79744|Hs108|chr19 ( 497) 958 122.8 7e-28 CCDS54327.1 ZNF419 gene_id:79744|Hs108|chr19 ( 498) 958 122.8 7e-28 CCDS54326.1 ZNF419 gene_id:79744|Hs108|chr19 ( 510) 958 122.8 7.1e-28 CCDS46211.1 ZNF419 gene_id:79744|Hs108|chr19 ( 464) 953 122.2 1e-27 CCDS42637.1 ZNF419 gene_id:79744|Hs108|chr19 ( 478) 953 122.2 1e-27 CCDS4441.1 ZNF454 gene_id:285676|Hs108|chr5 ( 522) 928 119.5 7.5e-27 CCDS12965.1 ZNF417 gene_id:147687|Hs108|chr19 ( 575) 898 116.1 8.3e-26 CCDS12964.1 ZNF587 gene_id:84914|Hs108|chr19 ( 575) 897 116.0 9e-26 CCDS10914.2 ZFP1 gene_id:162239|Hs108|chr16 ( 407) 881 113.9 2.7e-25 CCDS12501.1 ZNF383 gene_id:163087|Hs108|chr19 ( 475) 881 114.1 2.9e-25 CCDS47592.1 ZNF679 gene_id:168417|Hs108|chr7 ( 411) 876 113.4 4e-25 CCDS12954.1 ZNF416 gene_id:55659|Hs108|chr19 ( 594) 877 113.8 4.4e-25 CCDS46169.1 ZNF665 gene_id:79788|Hs108|chr19 ( 678) 871 113.2 7.5e-25 CCDS11179.2 ZNF287 gene_id:57336|Hs108|chr17 ( 761) 867 112.9 1.1e-24 CCDS12979.1 ZNF584 gene_id:201514|Hs108|chr19 ( 421) 862 111.8 1.2e-24 CCDS12945.1 ZNF471 gene_id:57573|Hs108|chr19 ( 626) 862 112.1 1.5e-24 CCDS7205.2 ZNF485 gene_id:220992|Hs108|chr10 ( 441) 858 111.4 1.7e-24 CCDS46062.1 ZNF793 gene_id:390927|Hs108|chr19 ( 406) 848 110.2 3.6e-24 CCDS42532.1 ZNF253 gene_id:56242|Hs108|chr19 ( 499) 849 110.5 3.7e-24 CCDS46101.1 ZNF234 gene_id:10780|Hs108|chr19 ( 700) 843 110.1 6.8e-24 CCDS34639.2 ZNF713 gene_id:349075|Hs108|chr7 ( 443) 822 107.3 2.9e-23 CCDS2011.1 ZNF514 gene_id:84874|Hs108|chr2 ( 400) 815 106.4 4.8e-23 CCDS32915.1 ZNF700 gene_id:90592|Hs108|chr19 ( 742) 818 107.3 5e-23 >>CCDS12963.1 ZNF552 gene_id:79818|Hs108|chr19 (407 aa) initn: 2871 init1: 2871 opt: 2871 Z-score: 1786.9 bits: 339.5 E(32554): 3.3e-93 Smith-Waterman score: 2871; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407) 10 20 30 40 50 60 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RSGLLQQEATHTGKSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RSGLLQQEATHTGKSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 CQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKS 310 320 330 340 350 360 370 380 390 400 pF1KE0 FAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL ::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 FAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL 370 380 390 400 >>CCDS46212.1 ZNF814 gene_id:730051|Hs108|chr19 (855 aa) initn: 3560 init1: 1314 opt: 2107 Z-score: 1316.2 bits: 253.5 E(32554): 5.4e-67 Smith-Waterman score: 2107; 76.0% identity (86.7% similar) in 405 aa overlap (2-405:3-405) 10 20 30 40 50 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGV :::.::. .:::::::::::.:: ::::::::::::::::::::::::.::::::::: CCDS46 MAAAATLRLSAQGTVTFEDVAVNFTWEEWNLLSEAQRCLYRDVTLENLALISSLGCWCGV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 RCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 LRSGLLQQEATHTG-KSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEE :::::::::.::: :::::::::: .. : .::::: ::::::: :::::.::: :: CCDS46 PRSGLLQQEASHTGEKSNSKTECVSPIQCGGAHYSCGESMKHFSTKHILSQHQRLLTREE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 PSVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYEC : :::::: ::: :.:::: ::: :: . :: ::: :.. . :::.:: :: .:: CCDS46 CYVCCECGKSFSKYASLSNHQRVHT-EKKHECGECGKSFSKYVSFSNHQRVHT-EKKHEC 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 EVCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECG : : : . . :::::::.:::::..:::::.. ..: :.:::: .: :::.::: CCDS46 GECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVHTEKKHYECGECG 300 310 320 330 340 350 360 370 380 390 400 pF1KE0 KSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL :::.. :...:.:::::..:: :.:: :.: . .:. .::::: : CCDS46 KSFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVHTDKKHYECGECGKSFS 360 370 380 390 400 410 CCDS46 QKSSLIQHQRFHTGEKPYGCEECGKSFSSEGHLRSHQRVHAGERPFKCGECVKSFSHKRS 420 430 440 450 460 470 >-- initn: 1746 init1: 968 opt: 1045 Z-score: 665.5 bits: 133.1 E(32554): 9.5e-31 Smith-Waterman score: 1059; 49.4% identity (70.2% similar) in 336 aa overlap (86-402:487-822) 60 70 80 90 100 110 pF1KE0 WCGVEDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHK : .. . : :: ... ... :: .: CCDS46 VHAGERPFKCGECVKSFSHKRSLVHHQRVHSGERPYQCGECGKSFSQKGNLVLHQRVHTG 460 470 480 490 500 510 120 130 140 150 160 pF1KE0 QKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYR-GSVEEALFAK-----RCKLHVSGESS . ..: :... ..:....::. : :.. :. : ... : . ..: .: CCDS46 ARPYECGECGKSFSSKGHLRNHQQIHTGDRLYECGECGKSFSHKGTLILHQRVHPRERSY 520 530 540 550 560 570 170 180 190 200 210 pF1KE0 VFSESGKDFLLRSGLLQQEATHTGKSNSKT-ECVSLF------------HGGKSHYSCGG .: ::.: . : ... .:::. . :: . : : :. :.:: CCDS46 GCGECGKSFSSIGHLRSHQRVHTGERPYECGECGKSFSHKRSLVHHQRMHTGERPYKCGD 580 590 600 610 620 630 220 230 240 250 260 270 pF1KE0 CMKHFSTKDILSQHERLLPTEEPSVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKL : : :. : : .:.:. ::.: :::: :. .. :: :: :.::.: :::: CCDS46 CGKSFNEKGHLRNHQRVHTTERPFKCGECGKCFSHKGNLILHQHGHTGERPYVCRECGKL 640 650 660 670 680 690 280 290 300 310 320 330 pF1KE0 FNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHS :..:::::::::::.::::: ::.::::::.::.::::::::::::::::.::::::::: CCDS46 FKKKSHLLVHQRIHNGEKPYACEACQKFFRNKYQLIAHQRVHTGERPYECNDCGKSFTHS 700 710 720 730 740 750 340 350 360 370 380 390 pF1KE0 STFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLR ::: ::::.:::.:::::::::::::::::.:::.::::::::: :::: :.: . ::: CCDS46 STFCVHKRIHTGEKPYECSECGKSFAESSSFTKHKRVHTGEKPYECSECGKSFAESSSLT 760 770 780 790 800 810 400 pF1KE0 HHQRVHKRKGL .:.::: CCDS46 KHKRVHTGEKPYKCEKCGKLFNKKSHLLVHQSSHWRKAI 820 830 840 850 >>CCDS56109.1 ZNF587B gene_id:100293516|Hs108|chr19 (402 aa) initn: 2006 init1: 1253 opt: 2010 Z-score: 1259.4 bits: 241.9 E(32554): 8e-64 Smith-Waterman score: 2010; 77.8% identity (89.2% similar) in 370 aa overlap (4-372:5-374) 10 20 30 40 50 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGV :.::. .::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MAVVATLRLSAQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLH ::::::::::::::::::::::..:::::::::::::::::::::::::::::::::::: CCDS56 EDEAAPSKQSIYIQRETQVRTPVTGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 RCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFL :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS56 RCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFVKRCKLHVSGESSVFSESGKDFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 LRSGLLQQEATHTG-KSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEE :::::::::.::: :::::::::: :. : .::: : ::::::: :::::.:::: :: CCDS56 PRSGLLQQEASHTGEKSNSKTECVSPFQCGGAHYSHGDSMKHFSTKHILSQHQRLLPREE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 PSVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYEC : :::::: ::: :::::: ::. ..:: :: : : :..:: :. ::..::: ::: : CCDS56 CYVCCECGKSFSKYVSFSNHQRVHSGKRPYECGECEKSFSQKSSLIQHQQFHTGGKPYGC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 EVCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECG : : :.: . .: ::.::.:. ::::..:::::. . ... :.:.:::..::.:.:: CCDS56 EECGKYFSLEGYLRRHQKVHAGKGPYECGECGKSFSSNVNLKSHQRIHTGERPYKCGECE 310 320 330 340 350 360 360 370 380 390 400 pF1KE0 KSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL :::... ::. :.: CCDS56 KSFSRKPSLSYHQRFGRPRWVDHKDRKEFKTSLGNIVKSCLF 370 380 390 400 >>CCDS82410.1 ZNF418 gene_id:147686|Hs108|chr19 (697 aa) initn: 3690 init1: 1015 opt: 1907 Z-score: 1194.3 bits: 230.7 E(32554): 3.3e-60 Smith-Waterman score: 1907; 68.3% identity (83.4% similar) in 397 aa overlap (10-405:22-416) 10 20 30 40 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLA :::::.::::::.:.::::.::::.:::::.:: ::: . CCDS82 MQEGLHRMTWDCIAIGSHENSVQGTVAFEDVAVNFSQEEWSLLSEVQRCLYHDVMLENWV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 LMSSLGCWCGVEDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVAD :.:::::::: ::: ::::.:: ::: .:: :: ::::::::: ::::: :::::::.:: CCDS82 LISSLGCWCGSEDEEAPSKKSISIQRVSQVSTPGAGVSPKKAHSCEMCGAILGDILHLAD 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 HQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGES :::::::::::::::::::::::.: . :::...::::::.:::::::.::::.::: :: CCDS82 HQGTHHKQKLHRCEAWGNKLYDSSN-RPHQNQYLGEKPYRSSVEEALFVKRCKFHVSEES 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 SVFSESGKDFLLRSGLLQQEATHTG-KSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDIL :.: .:::::: :::: ::::::: ::::: :: : :. : .::::: :::: ::: .. CCDS82 SIFIQSGKDFLPSSGLLLQEATHTGEKSNSKPECESPFQWGDTHYSCGECMKHSSTKHVF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 SQHERLLPTEEPSVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQ :..:: :: : ::::: ::::: :::: ::: ..:: :: ::: :. :. :. :: CCDS82 VQQQRLPSREECYCW-ECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQ 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 RIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHT :.:::..:::: : : : :: :. :::::::::::::..:::::....:. :.:::: CCDS82 RVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVHT 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 GQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL :..:::: :::: :.....: .:.: ::.:.:: : :: : : : ..: .:.::: :. CCDS82 GERPYECEECGKCFTQKGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERP 360 370 380 390 400 410 CCDS82 YECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECR 420 430 440 450 460 470 >-- initn: 1701 init1: 790 opt: 791 Z-score: 510.6 bits: 104.2 E(32554): 4.1e-22 Smith-Waterman score: 791; 66.5% identity (82.0% similar) in 161 aa overlap (243-402:421-581) 220 230 240 250 260 270 pF1KE0 SCGGCMKHFSTKDILSQHERLLPTEEPSVWC-ECGKSSSKYDSFSNHQGVHTREKPYTCG : ::::: :. . ::: :: :.:: :: CCDS82 YECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECG 400 410 420 430 440 450 280 290 300 310 320 330 pF1KE0 ICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYECSDCGK ::: :. :..:. ::: ::::.::::. :.:.:: : ::: :::::::::::::..::: CCDS82 ECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGK 460 470 480 490 500 510 340 350 360 370 380 390 pF1KE0 SFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQ :: :: ::::.:::::.::.::::::::: .: :: .::::::::.:: :.:: :.:.: CCDS82 SFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHTGERPYECGECGKSFHQ 520 530 540 550 560 570 400 pF1KE0 ISSLRHHQRVHKRKGL ::: .::..: CCDS82 SSSLLRHQKTHTAERPYECRECGKFFSSLLEHRRVHTGERPYECRECGKTFTRRSAHFKH 580 590 600 610 620 630 >-- initn: 785 init1: 450 opt: 530 Z-score: 350.6 bits: 74.6 E(32554): 3.3e-13 Smith-Waterman score: 530; 64.3% identity (81.7% similar) in 115 aa overlap (291-405:582-693) 270 280 290 300 310 320 pF1KE0 VHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTG :.:.::::. : ::: :. :.::::: CCDS82 VHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSS---LLEHRRVHTG 560 570 580 590 600 330 340 350 360 370 380 pF1KE0 ERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPY :::::: .:::.::. :. :.:.:: ::::::::::::::. :::.::::::::.:: CCDS82 ERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVHTGERPY 610 620 630 640 650 660 390 400 pF1KE0 GCSECEKKFRQISSLRHHQRVHKRKGL :::: :.:.. ::: .::::: .. CCDS82 ECSECGKSFHRSSSLLRHQRVHTERSPYK 670 680 690 >>CCDS42642.1 ZNF418 gene_id:147686|Hs108|chr19 (676 aa) initn: 3686 init1: 1015 opt: 1903 Z-score: 1192.0 bits: 230.2 E(32554): 4.5e-60 Smith-Waterman score: 1903; 68.0% identity (83.4% similar) in 397 aa overlap (10-405:1-395) 10 20 30 40 50 60 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVE .::::.::::::.:.::::.::::.:::::.:: ::: .:.:::::::: : CCDS42 MQGTVAFEDVAVNFSQEEWSLLSEVQRCLYHDVMLENWVLISSLGCWCGSE 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 DEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHR :: ::::.:: ::: .:: :: ::::::::: ::::: :::::::.:::::::::::::: CCDS42 DEEAPSKKSISIQRVSQVSTPGAGVSPKKAHSCEMCGAILGDILHLADHQGTHHKQKLHR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLL :::::::::::.: . :::...::::::.:::::::.::::.::: :::.: .:::::: CCDS42 CEAWGNKLYDSSN-RPHQNQYLGEKPYRSSVEEALFVKRCKFHVSEESSIFIQSGKDFLP 120 130 140 150 160 170 190 200 210 220 230 pF1KE0 RSGLLQQEATHTG-KSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEP :::: ::::::: ::::: :: : :. : .::::: :::: ::: .. :..:: :: CCDS42 SSGLLLQEATHTGEKSNSKPECESPFQWGDTHYSCGECMKHSSTKHVFVQQQRLPSREEC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 SVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECE : ::::: ::::: :::: ::: ..:: :: ::: :. :. :. :::.:::..:::: CCDS42 YCW-ECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGKRPYECG 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 VCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGK : : : :: :. :::::::::::::..:::::....:. :.:::::..:::: :::: CCDS42 ECGKSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVHTGERPYECEECGK 290 300 310 320 330 340 360 370 380 390 400 pF1KE0 SFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL :.....: .:.: ::.:.:: : :: : : : ..: .:.::: :. CCDS42 CFTQKGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSR 350 360 370 380 390 400 CCDS42 KGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHL 410 420 430 440 450 460 >-- initn: 1701 init1: 790 opt: 791 Z-score: 510.7 bits: 104.1 E(32554): 4e-22 Smith-Waterman score: 791; 66.5% identity (82.0% similar) in 161 aa overlap (243-402:400-560) 220 230 240 250 260 270 pF1KE0 SCGGCMKHFSTKDILSQHERLLPTEEPSVWC-ECGKSSSKYDSFSNHQGVHTREKPYTCG : ::::: :. . ::: :: :.:: :: CCDS42 YECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECG 370 380 390 400 410 420 280 290 300 310 320 330 pF1KE0 ICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYECSDCGK ::: :. :..:. ::: ::::.::::. :.:.:: : ::: :::::::::::::..::: CCDS42 ECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGK 430 440 450 460 470 480 340 350 360 370 380 390 pF1KE0 SFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQ :: :: ::::.:::::.::.::::::::: .: :: .::::::::.:: :.:: :.:.: CCDS42 SFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHTGERPYECGECGKSFHQ 490 500 510 520 530 540 400 pF1KE0 ISSLRHHQRVHKRKGL ::: .::..: CCDS42 SSSLLRHQKTHTAERPYECRECGKFFSSLLEHRRVHTGERPYECRECGKTFTRRSAHFKH 550 560 570 580 590 600 >-- initn: 785 init1: 450 opt: 530 Z-score: 350.7 bits: 74.6 E(32554): 3.2e-13 Smith-Waterman score: 530; 64.3% identity (81.7% similar) in 115 aa overlap (291-405:561-672) 270 280 290 300 310 320 pF1KE0 VHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTG :.:.::::. : ::: :. :.::::: CCDS42 VHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSS---LLEHRRVHTG 540 550 560 570 580 330 340 350 360 370 380 pF1KE0 ERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPY :::::: .:::.::. :. :.:.:: ::::::::::::::. :::.::::::::.:: CCDS42 ERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVHTGERPY 590 600 610 620 630 640 390 400 pF1KE0 GCSECEKKFRQISSLRHHQRVHKRKGL :::: :.:.. ::: .::::: .. CCDS42 ECSECGKSFHRSSSLLRHQRVHTERSPYK 650 660 670 >>CCDS56110.1 ZNF587 gene_id:84914|Hs108|chr19 (574 aa) initn: 4453 init1: 870 opt: 1592 Z-score: 1002.0 bits: 194.8 E(32554): 1.7e-49 Smith-Waterman score: 1592; 59.5% identity (76.4% similar) in 402 aa overlap (1-402:1-401) 10 20 30 40 50 60 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVE ::::. : :.:::::::::::.:.:::: ::::::::::::: ::::::.:::::::: . CCDS56 MAAAVPRRPTQGTVTFEDVAVNFSQEEWCLLSEAQRCLYRDVMLENLALISSLGCWCGSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHR :: :: :: : .:::.: ::: ::::::::::::::: :: :..: :::: :::::::.: CCDS56 DEEAPCKQRISVQRESQSRTPRAGVSPKKAHPCEMCGLILEDVFHFADHQETHHKQKLNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLL : :..: :.. .::::..::::: :: ::.:: :.:. ::.:: : :: : ::: : CCDS56 SGACGKNLDDTAYLHQHQKQHIGEKFYRKSVREASFVKKRKLRVSQEPFVFREFGKDVLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RSGLLQQEATHTGKSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPS ::: :.::. . :..:.: :. ::..:::: : :::: . :..:. . CCDS56 SSGLCQEEAA-VEKTDSETMHGPPFQEGKTNYSCGKRTKAFSTKHSVIPHQKLFTRDGCY 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 VWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEV : .:::: :.: :::::: :: . :: :: ::: .. :: :. :::.:::. : :: CCDS56 VCSDCGKSFSRYVSFSNHQRDHTAKGPYDCGECGKSYSRKSSLIQHQRVHTGQTAYPCEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 CQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKS : : : .: ::.:: ::::: :::: .::::: ..... :.. :::.. :.:.::::: CCDS56 CGKSFSQKGSLISHQLVHTGEGPYECRECGKSFGQKGNLIQHQQGHTGERAYHCGECGKS 300 310 320 330 340 350 370 380 390 400 pF1KE0 FAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL : .. . .:.::::::.:: :.:: :.: : ..: :::: : CCDS56 FRQKFCFINHQRVHTGERPYKCGECGKSFGQKGNLVHHQRGHTGERPYECKECGKSFRYR 360 370 380 390 400 410 CCDS56 SHLTEHQRLHTGERPYNCRECGKLFNRKYHLLVHERVHTGERPYACEVCGKLFGNKHSVT 420 430 440 450 460 470 >-- initn: 1766 init1: 803 opt: 806 Z-score: 520.4 bits: 105.7 E(32554): 1.1e-22 Smith-Waterman score: 806; 62.6% identity (81.3% similar) in 171 aa overlap (237-407:404-574) 210 220 230 240 250 260 pF1KE0 GGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPSVWCECGKSSSKYDSFSNHQGVHTREK :.: ::::: . ...:: .:: :. CCDS56 TGERPYKCGECGKSFGQKGNLVHHQRGHTGERPYECKECGKSFRYRSHLTEHQRLHTGER 380 390 400 410 420 430 270 280 290 300 310 320 pF1KE0 PYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYEC ::.: :::::: : :::::.:.::::.:: :::: :.: .:. . :::.::::::::: CCDS56 PYNCRECGKLFNRKYHLLVHERVHTGERPYACEVCGKLFGNKHSVTIHQRIHTGERPYEC 440 450 460 470 480 490 330 340 350 360 370 380 pF1KE0 SDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECE :.::::: ::...::::::.:::::.::::::::.: ::: ::::.::::.:: :..: CCDS56 SECGKSFLSSSALHVHKRVHSGQKPYKCSECGKSFSECSSLIKHRRIHTGERPYECTKCG 500 510 520 530 540 550 390 400 pF1KE0 KKFRQISSLRHHQRVHKRKGL : :.. :.: ::: :.::.: CCDS56 KTFQRSSTLLHHQSSHRRKAL 560 570 >>CCDS74469.1 ZNF417 gene_id:147687|Hs108|chr19 (574 aa) initn: 4481 init1: 868 opt: 1587 Z-score: 998.9 bits: 194.3 E(32554): 2.5e-49 Smith-Waterman score: 1587; 59.7% identity (76.4% similar) in 402 aa overlap (1-402:1-401) 10 20 30 40 50 60 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVE ::::: : :.:::::::::::.:.:::: ::::::::::::: ::::::.:::::::: . CCDS74 MAAAAPRRPTQGTVTFEDVAVNFSQEEWCLLSEAQRCLYRDVMLENLALISSLGCWCGSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHR :: :: :: : .:::.: ::: ::::::::::::::: :: :..: :::: :::::::.: CCDS74 DEEAPCKQRISVQRESQSRTPRAGVSPKKAHPCEMCGLILEDVFHFADHQETHHKQKLNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLL : :..: :.. .::::..::::: :: ::.:: :.:. ::.:: : :: : ::: : CCDS74 SGACGKNLDDTAYLHQHQKQHIGEKFYRKSVREASFVKKRKLRVSQEPFVFREFGKDVLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RSGLLQQEATHTGKSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPS ::: : ::. . :..:.: :. ::..:::: : :::: . :..:. . CCDS74 SSGLCQ-EAAAVEKTDSETMHGPPFQEGKTNYSCGKRTKAFSTKHSVIPHQKLFTRDGCY 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 VWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEV : .:::: :.: :::::: :: . :: :: ::: .. :: :. :::.:::. : :: CCDS74 VCSDCGKSFSRYVSFSNHQRDHTAKGPYDCGECGKSYSRKSSLIQHQRVHTGKTAYPCEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 CQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKS : : : .: ::.::::::::::::: . :::: ..... :.. :::.. :.:.::::: CCDS74 CGKSFSQKGSLISHQRVHTGERPYECREYGKSFGQKGNLIQHQQGHTGERAYHCGECGKS 300 310 320 330 340 350 370 380 390 400 pF1KE0 FAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL : .. . .:.::::::.:: :.:: :.: : ..: .::: : CCDS74 FRQKFCFINHQRVHTGERPYKCGECGKSFGQKGNLVQHQRGHTGERPYECKECGKSFRYR 360 370 380 390 400 410 CCDS74 SHLTEHQRLHTGERPYNCRECGKLFNRKYHLLVHERVHTGERPYACEVCGKLFGNKNCVT 420 430 440 450 460 470 >-- initn: 1416 init1: 797 opt: 800 Z-score: 516.7 bits: 105.0 E(32554): 1.8e-22 Smith-Waterman score: 800; 62.6% identity (80.7% similar) in 171 aa overlap (237-407:404-574) 210 220 230 240 250 260 pF1KE0 GGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPSVWCECGKSSSKYDSFSNHQGVHTREK :.: ::::: . ...:: .:: :. CCDS74 TGERPYKCGECGKSFGQKGNLVQHQRGHTGERPYECKECGKSFRYRSHLTEHQRLHTGER 380 390 400 410 420 430 270 280 290 300 310 320 pF1KE0 PYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYEC ::.: :::::: : :::::.:.::::.:: :::: :.: .: . :::.::::::::: CCDS74 PYNCRECGKLFNRKYHLLVHERVHTGERPYACEVCGKLFGNKNCVTIHQRIHTGERPYEC 440 450 460 470 480 490 330 340 350 360 370 380 pF1KE0 SDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECE ..::::: ::...::::::.:::::.:::::::::: ::: ::::.::::.:: :..: CCDS74 NECGKSFLSSSALHVHKRVHSGQKPYKCSECGKSFAECSSLIKHRRIHTGERPYECTKCG 500 510 520 530 540 550 390 400 pF1KE0 KKFRQISSLRHHQRVHKRKGL : :.. :.: ::: :.::.: CCDS74 KTFQRSSTLLHHQSSHRRKAL 560 570 >>CCDS12962.2 ZNF776 gene_id:284309|Hs108|chr19 (518 aa) initn: 1840 init1: 862 opt: 1585 Z-score: 998.1 bits: 193.9 E(32554): 2.8e-49 Smith-Waterman score: 1585; 58.1% identity (77.7% similar) in 403 aa overlap (1-402:1-398) 10 20 30 40 50 60 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVE ::::::: :.:::::::::::.:.::::.::::::::::.:: ::::.:.:::::: :.. CCDS12 MAAAALRPPAQGTVTFEDVAVNFSQEEWSLLSEAQRCLYHDVMLENLTLISSLGCWYGAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHR ::. ::::.. ::.:. .:: .:: ::.: ::::.:::::: :::.:.:::. CCDS12 DET-PSKQTLSIQQESPLRTHWTGVCTKKVHLWGMCGPLLGDILH----QGTQHNQKLNG 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLL :. .:: :..: :: :..::::: ::.... . :.: ::.:.: : .: : ::::: CCDS12 FGAYEKKLDDDANHHQDQKQHIGEKSYRSNAKGTSFVKNCKFHMSHEPFIFHEVGKDFLS 120 130 140 150 160 170 190 200 210 220 230 pF1KE0 RSGLLQQEATHT-GKSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEP ::::: :: :::: .:. ..:::.:: :: ::.: : :.:::: : : CCDS12 SLRLLQQEDIHTSGKSNFETKHGIPLQGGKTHYICGESTIPFSNKHSLVLHQRLLPREGP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 SVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECE : . :: .:: .::.:::::.: ..:: :: : . : :.:: :::.::::.:::: CCDS12 YVCSDSGKFTSKSNSFNNHQGVRTGKRPYQCGQCDESFWYKAHLTEHQRVHTGERPYECG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 VCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGK :.: : ::. :. :::::::::::::..:::::.:. .. :.:::::..::.:.:::: CCDS12 ECDKSFSHKHSLVDHQRVHTGERPYECDECGKSFSHKRSLVHHQRVHTGERPYQCGECGK 300 310 320 330 340 350 360 370 380 390 400 pF1KE0 SFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL :: .. .: .:.::::::.:. :. : : ::. : :..::::: CCDS12 SFNHKCNLIQHQRVHTGERPFECTACGKLFRSNSHLKEHQRVHTGERPYECKECRKSFRY 360 370 380 390 400 410 CCDS12 KSHLTEHQRVHTGERPYECRECGKCFHQKGSLIQHQQIHSGERPHECGECGKCFHQKGSL 420 430 440 450 460 470 >-- initn: 609 init1: 511 opt: 511 Z-score: 340.0 bits: 72.2 E(32554): 1.3e-12 Smith-Waterman score: 511; 55.4% identity (83.9% similar) in 112 aa overlap (291-402:399-510) 270 280 290 300 310 320 pF1KE0 VHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTG :::.::::. :.: ::.: :: ::::::: CCDS12 VHTGERPFECTACGKLFRSNSHLKEHQRVHTGERPYECKECRKSFRYKSHLTEHQRVHTG 370 380 390 400 410 420 330 340 350 360 370 380 pF1KE0 ERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPY :::::: .::: : ..... :...:.:..:.::.:::: : ...:: .:...:.::.:. CCDS12 ERPYECRECGKCFHQKGSLIQHQQIHSGERPHECGECGKCFHQKGSLIRHQQIHSGERPH 430 440 450 460 470 480 390 400 pF1KE0 GCSECEKKFRQISSLRHHQRVHKRKGL :.:: : ::: ..: .::::: CCDS12 ECGECGKCFRQKGNLIKHQRVHTGERHHEC 490 500 510 >>CCDS12966.1 ZNF256 gene_id:10172|Hs108|chr19 (627 aa) initn: 2593 init1: 1242 opt: 1497 Z-score: 943.5 bits: 184.1 E(32554): 3.1e-46 Smith-Waterman score: 1497; 54.1% identity (76.7% similar) in 407 aa overlap (1-406:1-405) 10 20 30 40 50 60 pF1KE0 MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVE :::: : :.:: :::::::: :. .::.::.:::.:::.:: ::::.: .::: :. CCDS12 MAAAELTAPAQGIVTFEDVAVYFSWKEWGLLDEAQKCLYHDVMLENLTLTTSLGG-SGAG 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 DEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHR :: :: .:: :: .::: : : ::.:..:::.:::.: .:::...:::::: :::. CCDS12 DEEAPYQQSTSPQRVSQVRIPKALPSPQKTNPCEICGPVLRQILHLVEHQGTHHGQKLYT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLL : ..: .. .::::..:.:.: .:.. . .: . : ..:::. . .: :::::. CCDS12 DGACRKQLQFTAYLHQHQKQHVGQKHFRSNGGRDMFLSSCTFEVSGKPFTCKEVGKDFLV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 RSGLLQQEATHTGKSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPS :: .:::.:.:: :....:. . ::. :.::. : :.: :: : . ::. : .: : CCDS12 RSRFLQQQAAHTRKKSNRTKSAVAFHSVKNHYNWGECVKAFSYKHVRVQHQGDL-IRERS 180 190 200 210 220 230 250 260 270 280 290 pF1KE0 VWC-ECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECE : ::::: : :.:.: ::: ::::::: ::: . ..: :..:.::::: .:..:. CCDS12 YMCSECGKSFSTSCSLSDHLRVHTSEKPYTCGECGKSYRQSSSLITHRRIHTGVRPHQCD 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 VCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGK : :.: .:: :. :::::::::::.::.:::::.:::.. .:.:.:::..::::::::: CCDS12 ECGKLFNRKYDLLIHQRVHTGERPYKCSECGKSFSHSSSLITHQRIHTGMRPYECSECGK 300 310 320 330 340 350 360 370 380 390 400 pF1KE0 SFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL :: .:::: :.::::: .:: :::: :.: : : .:.:.: .: CCDS12 SFIHSSSLITHQRVHTGTRPYMCSECGKSFSQSCHLIKHRRLHIGEGPYECSECGKLFTY 360 370 380 390 400 410 CCDS12 RSRFFQHQRVHTGVRSHECHECGKLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSYL 420 430 440 450 460 470 >-- initn: 1349 init1: 743 opt: 783 Z-score: 506.0 bits: 103.2 E(32554): 7.3e-22 Smith-Waterman score: 783; 51.3% identity (68.5% similar) in 232 aa overlap (172-403:410-626) 150 160 170 180 190 200 pF1KE0 IGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLLRSGLLQQEATHTGKSNSKTEC :: :: : :: ..:.. .::: CCDS12 MCSECGKSFSQSCHLIKHRRLHIGEGPYECSECGKLFTYRSRFFQHQRVHTGV------- 380 390 400 410 420 430 210 220 230 240 250 260 pF1KE0 VSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPSVWCECGKSSSKYDSFSNHQGV .:: : : : :: : : :::. :.: ::::: . . . .: : CCDS12 -------RSH-ECHECGKLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSYLISHWKV 440 450 460 470 480 270 280 290 300 310 320 pF1KE0 HTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGE :: .:: :: ::: :. .: :: :::.::::.::::. : ::: .. :: :.: :::: CCDS12 HTGARPYECGECGKSFTHSSTLLQHQRVHTGERPYECNECGKFFSQSSSLIRHRRSHTGE 490 500 510 520 530 540 330 340 350 360 370 380 pF1KE0 RPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYG ::::::.: :::.. :.. :.:::::..:::::::::::..::.::.:.:.:.::.:: CCDS12 RPYECSECWKSFSNHSSLVKHRRVHTGERPYECSECGKSFSQSSNLTNHQRIHSGERPYE 550 560 570 580 590 600 390 400 pF1KE0 CSECEKKFRQISSLRHHQRVHKRKGL ::.: : : :.: .:: ::: CCDS12 CSDCGKFFTFNSNLLKHQNVHKG 610 620 >>CCDS82409.1 ZNF418 gene_id:147686|Hs108|chr19 (591 aa) initn: 1015 init1: 1015 opt: 1455 Z-score: 918.0 bits: 179.3 E(32554): 8.2e-45 Smith-Waterman score: 1455; 65.7% identity (81.7% similar) in 312 aa overlap (95-405:1-310) 70 80 90 100 110 120 pF1KE0 PSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAW ::: :::::::.:::::::::::::::::: CCDS82 MCGAILGDILHLADHQGTHHKQKLHRCEAW 10 20 30 130 140 150 160 170 180 pF1KE0 GNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLLRSGL :::::::.: . :::...::::::.:::::::.::::.::: :::.: .:::::: ::: CCDS82 GNKLYDSSN-RPHQNQYLGEKPYRSSVEEALFVKRCKFHVSEESSIFIQSGKDFLPSSGL 40 50 60 70 80 190 200 210 220 230 240 pF1KE0 LQQEATHTG-KSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPSVWC : ::::::: ::::: :: : :. : .::::: :::: ::: .. :..:: :: : CCDS82 LLQEATHTGEKSNSKPECESPFQWGDTHYSCGECMKHSSTKHVFVQQQRLPSREECYCW- 90 100 110 120 130 140 250 260 270 280 290 300 pF1KE0 ECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQK ::::: ::::: :::: ::: ..:: :: ::: :. :. :. :::.:::..:::: : : CCDS82 ECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGKRPYECGECGK 150 160 170 180 190 200 310 320 330 340 350 360 pF1KE0 FFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAE : :: :. :::::::::::::..:::::....:. :.:::::..:::: :::: :.. CCDS82 SFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVHTGERPYECEECGKCFTQ 210 220 230 240 250 260 370 380 390 400 pF1KE0 SSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL ...: .:.: ::.:.:: : :: : : : ..: .:.::: :. CCDS82 KGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHL 270 280 290 300 310 320 CCDS82 RNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQ 330 340 350 360 370 380 >-- initn: 1701 init1: 790 opt: 791 Z-score: 511.1 bits: 104.0 E(32554): 3.8e-22 Smith-Waterman score: 791; 66.5% identity (82.0% similar) in 161 aa overlap (243-402:315-475) 220 230 240 250 260 270 pF1KE0 SCGGCMKHFSTKDILSQHERLLPTEEPSVWC-ECGKSSSKYDSFSNHQGVHTREKPYTCG : ::::: :. . ::: :: :.:: :: CCDS82 YECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECG 290 300 310 320 330 340 280 290 300 310 320 330 pF1KE0 ICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYECSDCGK ::: :. :..:. ::: ::::.::::. :.:.:: : ::: :::::::::::::..::: CCDS82 ECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGK 350 360 370 380 390 400 340 350 360 370 380 390 pF1KE0 SFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQ :: :: ::::.:::::.::.::::::::: .: :: .::::::::.:: :.:: :.:.: CCDS82 SFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHTGERPYECGECGKSFHQ 410 420 430 440 450 460 400 pF1KE0 ISSLRHHQRVHKRKGL ::: .::..: CCDS82 SSSLLRHQKTHTAERPYECRECGKFFSSLLEHRRVHTGERPYECRECGKTFTRRSAHFKH 470 480 490 500 510 520 >-- initn: 785 init1: 450 opt: 530 Z-score: 351.2 bits: 74.4 E(32554): 3e-13 Smith-Waterman score: 530; 64.3% identity (81.7% similar) in 115 aa overlap (291-405:476-587) 270 280 290 300 310 320 pF1KE0 VHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTG :.:.::::. : ::: :. :.::::: CCDS82 VHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSS---LLEHRRVHTG 450 460 470 480 490 500 330 340 350 360 370 380 pF1KE0 ERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPY :::::: .:::.::. :. :.:.:: ::::::::::::::. :::.::::::::.:: CCDS82 ERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVHTGERPY 510 520 530 540 550 560 390 400 pF1KE0 GCSECEKKFRQISSLRHHQRVHKRKGL :::: :.:.. ::: .::::: .. CCDS82 ECSECGKSFHRSSSLLRHQRVHTERSPYK 570 580 590 407 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:53:51 2016 done: Sat Nov 5 02:53:52 2016 Total Scan time: 2.940 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]