Result of FASTA (omim) for
pF1KE0709
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0709, 295 aa
1>>>pF1KE0709 295 - 295 aa - 295 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5257+/-0.000337; mu= 14.6295+/- 0.021
mean_var=77.8047+/-15.490, 0's: 0 Z-trim(114.8): 53 B-trim: 64 in 1/49
Lambda= 0.145402
statistics sampled from 24835 (24876) to 24835 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.292), width: 16
Scan time: 7.230
The best scores are: opt bits E(85289)
NP_036240 (OMIM: 604298) signal-transducing adapto ( 295) 1932 414.6 1.1e-115
NP_001304698 (OMIM: 604298) signal-transducing ada ( 295) 1932 414.6 1.1e-115
XP_016863507 (OMIM: 604298) PREDICTED: signal-tran ( 314) 1433 310.0 3.8e-84
NP_001013863 (OMIM: 607881) signal-transducing ada ( 403) 324 77.4 5e-14
XP_011526425 (OMIM: 607881) PREDICTED: signal-tran ( 448) 324 77.4 5.5e-14
NP_060190 (OMIM: 607881) signal-transducing adapto ( 449) 324 77.4 5.5e-14
NP_690874 (OMIM: 604071) diacylglycerol kinase eta (1164) 161 43.5 0.0023
NP_001191433 (OMIM: 604071) diacylglycerol kinase (1164) 161 43.5 0.0023
NP_821077 (OMIM: 604071) diacylglycerol kinase eta (1220) 161 43.5 0.0024
>>NP_036240 (OMIM: 604298) signal-transducing adaptor pr (295 aa)
initn: 1932 init1: 1932 opt: 1932 Z-score: 2197.7 bits: 414.6 E(85289): 1.1e-115
Smith-Waterman score: 1932; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KE0 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYTDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILTVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPACFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPACFY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TVSRKEATEMLQKNPSLGNMILRPGSDSRNYSITIRQEIDIPRIKHYKVMSVGQNYTIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TVSRKEATEMLQKNPSLGNMILRPGSDSRNYSITIRQEIDIPRIKHYKVMSVGQNYTIEL
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 EKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNPHIA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNPHIA
250 260 270 280 290
>>NP_001304698 (OMIM: 604298) signal-transducing adaptor (295 aa)
initn: 1932 init1: 1932 opt: 1932 Z-score: 2197.7 bits: 414.6 E(85289): 1.1e-115
Smith-Waterman score: 1932; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KE0 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYTDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILTVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPACFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPACFY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TVSRKEATEMLQKNPSLGNMILRPGSDSRNYSITIRQEIDIPRIKHYKVMSVGQNYTIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVSRKEATEMLQKNPSLGNMILRPGSDSRNYSITIRQEIDIPRIKHYKVMSVGQNYTIEL
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 EKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNPHIA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNPHIA
250 260 270 280 290
>>XP_016863507 (OMIM: 604298) PREDICTED: signal-transduc (314 aa)
initn: 1433 init1: 1433 opt: 1433 Z-score: 1631.6 bits: 310.0 E(85289): 3.8e-84
Smith-Waterman score: 1433; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220)
10 20 30 40 50 60
pF1KE0 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYTDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILTVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPACFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPACFY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TVSRKEATEMLQKNPSLGNMILRPGSDSRNYSITIRQEIDIPRIKHYKVMSVGQNYTIEL
::::::::::::::::::::::::::::::::::::::::
XP_016 TVSRKEATEMLQKNPSLGNMILRPGSDSRNYSITIRQEIDFAIDDDDDDDDDDDDMMSFF
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 EKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNPHIA
XP_016 CCCCCFLFLFFLRRGLALSHRLEYSGASSAHCHLRLPGSRHSPASASRVAGTTGAHHHAR
250 260 270 280 290 300
>>NP_001013863 (OMIM: 607881) signal-transducing adaptor (403 aa)
initn: 513 init1: 202 opt: 324 Z-score: 372.8 bits: 77.4 E(85289): 5e-14
Smith-Waterman score: 515; 33.9% identity (63.9% similar) in 277 aa overlap (3-272:4-249)
10 20 30 40 50
pF1KE0 MMAKKPPK-PAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
: .::. : :. .. . :.:.:: : :.:...:. :.: :..::.
NP_001 MASALRPPRVPKPKGVLPSH--------YYESFLEKKGPCDRDYKKFWAGLQGLTIYFYN
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 DKKSIIYVDKLDIVDLTCLTEQ---NSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGF
..... .:.::.. . ::.. .:.. ..:.:.: .:...:.:. : : :.::
NP_001 SNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ILTVTELSVPQNVSLLPGQVIKLHEVLEREKKRR-IETEQSTSVEKEKEPTEDYVDVLNP
::::.:: :: ...::::.. . ::: .:. :: .::
NP_001 ILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALET----------------------
120 130 140 150
180 190 200 210 220 230
pF1KE0 MPACFYTVSRKEATEMLQKNPSLGNMILRPGSDSRN-YSITIRQEIDIPRI-KHYKVMSV
:.:: ::: :: .:.. : ::..:::..:. . :.: :: . .. .::::
NP_001 -PSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKRE
160 170 180 190 200
240 250 260 270 280 290
pF1KE0 GQNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNP
: .:.:..:.: . .: .:..:::..:. : ::. . :
NP_001 GPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWV
210 220 230 240 250 260
pF1KE0 HIA
NP_001 APSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVAS
270 280 290 300 310 320
>>XP_011526425 (OMIM: 607881) PREDICTED: signal-transduc (448 aa)
initn: 513 init1: 202 opt: 324 Z-score: 372.1 bits: 77.4 E(85289): 5.5e-14
Smith-Waterman score: 515; 33.9% identity (63.9% similar) in 277 aa overlap (3-272:4-249)
10 20 30 40 50
pF1KE0 MMAKKPPK-PAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
: .::. : :. .. . :.:.:: : :.:...:. :.: :..::.
XP_011 MASALRPPRVPKPKGVLPSH--------YYESFLEKKGPCDRDYKKFWAGLQGLTIYFYN
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 DKKSIIYVDKLDIVDLTCLTEQ---NSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGF
..... .:.::.. . ::.. .:.. ..:.:.: .:...:.:. : : :.::
XP_011 SNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ILTVTELSVPQNVSLLPGQVIKLHEVLEREKKRR-IETEQSTSVEKEKEPTEDYVDVLNP
::::.:: :: ...::::.. . ::: .:. :: .::
XP_011 ILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALET----------------------
120 130 140 150
180 190 200 210 220 230
pF1KE0 MPACFYTVSRKEATEMLQKNPSLGNMILRPGSDSRN-YSITIRQEIDIPRI-KHYKVMSV
:.:: ::: :: .:.. : ::..:::..:. . :.: :: . .. .::::
XP_011 -PSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKRE
160 170 180 190 200
240 250 260 270 280 290
pF1KE0 GQNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNP
: .:.:..:.: . .: .:..:::..:. : ::. . :
XP_011 GPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWV
210 220 230 240 250 260
pF1KE0 HIA
XP_011 APSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVAS
270 280 290 300 310 320
>>NP_060190 (OMIM: 607881) signal-transducing adaptor pr (449 aa)
initn: 513 init1: 202 opt: 324 Z-score: 372.1 bits: 77.4 E(85289): 5.5e-14
Smith-Waterman score: 515; 33.9% identity (63.9% similar) in 277 aa overlap (3-272:4-249)
10 20 30 40 50
pF1KE0 MMAKKPPK-PAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
: .::. : :. .. . :.:.:: : :.:...:. :.: :..::.
NP_060 MASALRPPRVPKPKGVLPSH--------YYESFLEKKGPCDRDYKKFWAGLQGLTIYFYN
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 DKKSIIYVDKLDIVDLTCLTEQ---NSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGF
..... .:.::.. . ::.. .:.. ..:.:.: .:...:.:. : : :.::
NP_060 SNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ILTVTELSVPQNVSLLPGQVIKLHEVLEREKKRR-IETEQSTSVEKEKEPTEDYVDVLNP
::::.:: :: ...::::.. . ::: .:. :: .::
NP_060 ILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALET----------------------
120 130 140 150
180 190 200 210 220 230
pF1KE0 MPACFYTVSRKEATEMLQKNPSLGNMILRPGSDSRN-YSITIRQEIDIPRI-KHYKVMSV
:.:: ::: :: .:.. : ::..:::..:. . :.: :: . .. .::::
NP_060 -PSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKRE
160 170 180 190 200
240 250 260 270 280 290
pF1KE0 GQNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNP
: .:.:..:.: . .: .:..:::..:. : ::. . :
NP_060 GPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWV
210 220 230 240 250 260
pF1KE0 HIA
NP_060 APSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVAS
270 280 290 300 310 320
>>NP_690874 (OMIM: 604071) diacylglycerol kinase eta iso (1164 aa)
initn: 187 init1: 95 opt: 161 Z-score: 181.3 bits: 43.5 E(85289): 0.0023
Smith-Waterman score: 161; 32.1% identity (71.4% similar) in 84 aa overlap (29-112:69-149)
10 20 30 40 50
pF1KE0 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
:: :: . :....... . .::: ::..
NP_690 SDSEAEQEGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAK
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE0 DKKSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILT
:.::.:. :..:. : . . . ::.. .::.. : ....: .:: . :.:
NP_690 DSKSLIF-DEVDLSDAS--VAEASTKNANNSFTIITPFRRLMLCAENRKEMEDWISSLKS
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE0 VTELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPAC
NP_690 VQTREPYEVAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHK
160 170 180 190 200 210
>>NP_001191433 (OMIM: 604071) diacylglycerol kinase eta (1164 aa)
initn: 187 init1: 95 opt: 161 Z-score: 181.3 bits: 43.5 E(85289): 0.0023
Smith-Waterman score: 161; 32.1% identity (71.4% similar) in 84 aa overlap (29-112:69-149)
10 20 30 40 50
pF1KE0 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
:: :: . :....... . .::: ::..
NP_001 SDSEAEQEGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAK
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE0 DKKSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILT
:.::.:. :..:. : . . . ::.. .::.. : ....: .:: . :.:
NP_001 DSKSLIF-DEVDLSDAS--VAEASTKNANNSFTIITPFRRLMLCAENRKEMEDWISSLKS
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE0 VTELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPAC
NP_001 VQTREPYEVAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHK
160 170 180 190 200 210
>>NP_821077 (OMIM: 604071) diacylglycerol kinase eta iso (1220 aa)
initn: 135 init1: 95 opt: 161 Z-score: 181.0 bits: 43.5 E(85289): 0.0024
Smith-Waterman score: 161; 32.1% identity (71.4% similar) in 84 aa overlap (29-112:69-149)
10 20 30 40 50
pF1KE0 MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
:: :: . :....... . .::: ::..
NP_821 SDSEAEQEGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAK
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE0 DKKSIIYVDKLDIVDLTCLTEQNSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILT
:.::.:. :..:. : . . . ::.. .::.. : ....: .:: . :.:
NP_821 DSKSLIF-DEVDLSDAS--VAEASTKNANNSFTIITPFRRLMLCAENRKEMEDWISSLKS
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE0 VTELSVPQNVSLLPGQVIKLHEVLEREKKRRIETEQSTSVEKEKEPTEDYVDVLNPMPAC
NP_821 VQTREPYEVAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHK
160 170 180 190 200 210
295 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:54:29 2016 done: Sat Nov 5 02:54:30 2016
Total Scan time: 7.230 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]