FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0715, 304 aa 1>>>pF1KE0715 304 - 304 aa - 304 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7919+/-0.000469; mu= -3.2617+/- 0.029 mean_var=323.0168+/-64.940, 0's: 0 Z-trim(119.4): 59 B-trim: 841 in 1/57 Lambda= 0.071361 statistics sampled from 33336 (33395) to 33336 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.392), width: 16 Scan time: 6.280 The best scores are: opt bits E(85289) NP_060633 (OMIM: 616844) dnaJ homolog subfamily C ( 304) 1930 212.0 1.2e-54 XP_016877890 (OMIM: 616844) PREDICTED: dnaJ homolo ( 308) 1777 196.2 6.9e-50 XP_016877891 (OMIM: 616844) PREDICTED: dnaJ homolo ( 224) 1127 129.1 7.7e-30 NP_068572 (OMIM: 606060) dnaJ homolog subfamily C ( 198) 258 39.6 0.006 >>NP_060633 (OMIM: 616844) dnaJ homolog subfamily C memb (304 aa) initn: 1930 init1: 1930 opt: 1930 Z-score: 1101.8 bits: 212.0 E(85289): 1.2e-54 Smith-Waterman score: 1930; 100.0% identity (100.0% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KE0 MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EVLTDAAARAAYDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEEESRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EVLTDAAARAAYDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEEESRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TRTLEQEIERLREEGSRQLEEQQRLIREQIRQERDQRLRGKAENTEGQGTPKLKLKWKCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TRTLEQEIERLREEGSRQLEEQQRLIREQIRQERDQRLRGKAENTEGQGTPKLKLKWKCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KEDESKGGYSKDVLLRLLQKYGEVLNLVLSSKKPGTAVVEFATVKAAELAVQNEVGLVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KEDESKGGYSKDVLLRLLQKYGEVLNLVLSSKKPGTAVVEFATVKAAELAVQNEVGLVDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 PLKISWLEGQPQDAVGRSHSGLSKGSVLSERDYESLVMMRMRQAAERQQLIARMQQEDQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PLKISWLEGQPQDAVGRSHSGLSKGSVLSERDYESLVMMRMRQAAERQQLIARMQQEDQE 250 260 270 280 290 300 pF1KE0 GPPT :::: NP_060 GPPT >>XP_016877890 (OMIM: 616844) PREDICTED: dnaJ homolog su (308 aa) initn: 1777 init1: 1777 opt: 1777 Z-score: 1016.6 bits: 196.2 E(85289): 6.9e-50 Smith-Waterman score: 1777; 99.6% identity (100.0% similar) in 279 aa overlap (26-304:30-308) 10 20 30 40 50 pF1KE0 MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQL .:::::::::::::::::::::::::::::: XP_016 MSSLSFSSVCSSLTFHLKPFEGCVAHSSWQVKKAYRQKALSCHPDKNPDNPRAAELFHQL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 SQALEVLTDAAARAAYDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQALEVLTDAAARAAYDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 ESRSTRTLEQEIERLREEGSRQLEEQQRLIREQIRQERDQRLRGKAENTEGQGTPKLKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRSTRTLEQEIERLREEGSRQLEEQQRLIREQIRQERDQRLRGKAENTEGQGTPKLKLK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 WKCKKEDESKGGYSKDVLLRLLQKYGEVLNLVLSSKKPGTAVVEFATVKAAELAVQNEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WKCKKEDESKGGYSKDVLLRLLQKYGEVLNLVLSSKKPGTAVVEFATVKAAELAVQNEVG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 LVDNPLKISWLEGQPQDAVGRSHSGLSKGSVLSERDYESLVMMRMRQAAERQQLIARMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVDNPLKISWLEGQPQDAVGRSHSGLSKGSVLSERDYESLVMMRMRQAAERQQLIARMQQ 250 260 270 280 290 300 300 pF1KE0 EDQEGPPT :::::::: XP_016 EDQEGPPT >>XP_016877891 (OMIM: 616844) PREDICTED: dnaJ homolog su (224 aa) initn: 1182 init1: 1122 opt: 1127 Z-score: 656.7 bits: 129.1 E(85289): 7.7e-30 Smith-Waterman score: 1127; 95.2% identity (97.3% similar) in 188 aa overlap (26-212:30-217) 10 20 30 40 50 pF1KE0 MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQL .:::::::::::::::::::::::::::::: XP_016 MSSLSFSSVCSSLTFHLKPFEGCVAHSSWQVKKAYRQKALSCHPDKNPDNPRAAELFHQL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 SQALEVLTDAAARAAYDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQALEVLTDAAARAAYDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 ESRSTRTLEQEIERLREEGSRQLEEQQRLIREQIRQERDQRLRGKAENTEGQGTPKLKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRSTRTLEQEIERLREEGSRQLEEQQRLIREQIRQERDQRLRGKAENTEGQGTPKLKLK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 WKCKKEDESKGGYSKDVLLRLLQKYGEV-LNLVLSSKKPGTAVVEFATVKAAELAVQNEV :::::::::::::::::::::::: : : .. :::. XP_016 WKCKKEDESKGGYSKDVLLRLLQKVGPVDVHSFLSSQSTSQSTP 190 200 210 220 240 250 260 270 280 290 pF1KE0 GLVDNPLKISWLEGQPQDAVGRSHSGLSKGSVLSERDYESLVMMRMRQAAERQQLIARMQ >>NP_068572 (OMIM: 606060) dnaJ homolog subfamily C memb (198 aa) initn: 249 init1: 204 opt: 258 Z-score: 173.9 bits: 39.6 E(85289): 0.006 Smith-Waterman score: 262; 29.5% identity (63.2% similar) in 193 aa overlap (11-201:14-193) 10 20 30 40 50 pF1KE0 MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLS : :.::: .: .. ... .. .:: :::::.:.::.:.: :..:. NP_068 MDAILNYRSEDTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QALEVLTDAAARAAYDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEEE .: :.::. .:: ::. :.. : . :. . .:: ... : .... :: NP_068 KAKEILTNEESRARYDHWRRS--QMSMPFQQWEALNDSVKTSMHWVVR---GKKDLMLEE 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SRSTRTLEQEIERLREEGSRQLEEQQRLIREQIRQERDQRLRGKA--ENTEGQGTPKLKL : .:.: ..: :. :. :. :: :. .:.. . :. .. .:....: .. NP_068 SDKTHTTKMENEECNEQRERKKEELASTA-EKTEQKEPKPLEKSVSPQNSDSSGFADVN- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 KWKCKKEDESKGGYSKDVLLRLLQKYGEVLNLVLSSKKPGTAVVEFATVKAAELAVQNEV :. . . .:::. .::.:. NP_068 GWHLRFR------WSKDAPSELLRKFRNYEI 180 190 304 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:56:18 2016 done: Sat Nov 5 02:56:18 2016 Total Scan time: 6.280 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]