FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0717, 305 aa 1>>>pF1KE0717 305 - 305 aa - 305 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5910+/-0.000586; mu= 9.6495+/- 0.037 mean_var=467.0678+/-104.716, 0's: 0 Z-trim(117.5): 181 B-trim: 1738 in 1/53 Lambda= 0.059345 statistics sampled from 29427 (29633) to 29427 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.347), width: 16 Scan time: 6.920 The best scores are: opt bits E(85289) NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305) 2111 195.1 1.5e-49 NP_001317179 (OMIM: 605372) heterogeneous nuclear ( 331) 1103 108.8 1.5e-23 NP_001317180 (OMIM: 605372) heterogeneous nuclear ( 331) 1103 108.8 1.5e-23 NP_001317176 (OMIM: 605372) heterogeneous nuclear ( 356) 1046 104.0 4.6e-22 NP_001317177 (OMIM: 605372) heterogeneous nuclear ( 356) 1046 104.0 4.6e-22 NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378) 1046 104.0 4.7e-22 NP_001317178 (OMIM: 605372) heterogeneous nuclear ( 378) 1046 104.0 4.7e-22 NP_002127 (OMIM: 164017,615424,615426) heterogeneo ( 320) 1021 101.8 1.9e-21 XP_005268883 (OMIM: 164017,615424,615426) PREDICTE ( 372) 1004 100.4 5.6e-21 NP_112420 (OMIM: 164017,615424,615426) heterogeneo ( 372) 1004 100.4 5.6e-21 NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341) 939 94.8 2.6e-19 XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341) 939 94.8 2.6e-19 XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341) 939 94.8 2.6e-19 XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353) 939 94.8 2.6e-19 NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353) 939 94.8 2.6e-19 XP_016874740 (OMIM: 164017,615424,615426) PREDICTE ( 295) 897 91.1 2.9e-18 NP_112740 (OMIM: 607137,609115) heterogeneous nucl ( 420) 588 64.9 3.1e-10 NP_112737 (OMIM: 601324) heterogeneous nuclear rib ( 336) 585 64.5 3.4e-10 NP_112738 (OMIM: 601324) heterogeneous nuclear rib ( 355) 585 64.5 3.5e-10 NP_112556 (OMIM: 602688) heterogeneous nuclear rib ( 332) 581 64.1 4.3e-10 NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328) 531 59.8 8.3e-09 XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 526 59.5 1.1e-08 XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 526 59.5 1.1e-08 NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324) 520 58.9 1.6e-08 XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343) 512 58.2 2.6e-08 XP_011536665 (OMIM: 603328) PREDICTED: RNA-binding ( 332) 507 57.8 3.5e-08 NP_733839 (OMIM: 607897) RNA-binding protein Musas ( 251) 498 56.8 5.2e-08 NP_001309180 (OMIM: 607897) RNA-binding protein Mu ( 255) 498 56.8 5.2e-08 XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding ( 295) 499 57.0 5.3e-08 XP_006719466 (OMIM: 603328) PREDICTED: RNA-binding ( 351) 497 57.0 6.4e-08 XP_011536663 (OMIM: 603328) PREDICTED: RNA-binding ( 362) 497 57.0 6.5e-08 NP_002433 (OMIM: 603328) RNA-binding protein Musas ( 362) 497 57.0 6.5e-08 NP_004490 (OMIM: 602688) heterogeneous nuclear rib ( 285) 493 56.5 7.4e-08 NP_001003810 (OMIM: 601324) heterogeneous nuclear ( 287) 471 54.6 2.7e-07 NP_002129 (OMIM: 601324) heterogeneous nuclear rib ( 306) 471 54.6 2.8e-07 NP_001287758 (OMIM: 602649) cold-inducible RNA-bin ( 297) 359 45.0 0.00021 XP_016881726 (OMIM: 602649) PREDICTED: cold-induci ( 168) 352 44.0 0.00025 NP_001287744 (OMIM: 602649) cold-inducible RNA-bin ( 168) 352 44.0 0.00025 NP_001271 (OMIM: 602649) cold-inducible RNA-bindin ( 172) 344 43.3 0.00041 XP_006722700 (OMIM: 602649) PREDICTED: cold-induci ( 172) 344 43.3 0.00041 NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] ( 710) 354 45.3 0.00043 XP_011525970 (OMIM: 602649) PREDICTED: cold-induci ( 202) 344 43.4 0.00044 NP_000412 (OMIM: 113800,148080,607602,609165) kera ( 584) 350 44.8 0.0005 XP_005257400 (OMIM: 113800,148080,607602,609165) P ( 624) 350 44.9 0.00051 NP_000217 (OMIM: 144200,607606) keratin, type I cy ( 623) 341 44.1 0.00087 XP_016880670 (OMIM: 601574,612237) PREDICTED: TATA ( 323) 333 42.9 0.001 NP_000418 (OMIM: 152445,604117) loricrin [Homo sap ( 312) 332 42.8 0.0011 NP_006112 (OMIM: 113800,139350,144200,146590,60096 ( 644) 336 43.7 0.0012 XP_011523617 (OMIM: 601574,612237) PREDICTED: TATA ( 501) 333 43.2 0.0013 NP_003478 (OMIM: 601574,612237) TATA-binding prote ( 589) 333 43.4 0.0014 >>NP_006796 (OMIM: 609409) heterogeneous nuclear ribonuc (305 aa) initn: 2111 init1: 2111 opt: 2111 Z-score: 1010.5 bits: 195.1 E(85289): 1.5e-49 Smith-Waterman score: 2111; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305) 10 20 30 40 50 60 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGY 250 260 270 280 290 300 pF1KE0 GGSSF ::::: NP_006 GGSSF >>NP_001317179 (OMIM: 605372) heterogeneous nuclear ribo (331 aa) initn: 1292 init1: 887 opt: 1103 Z-score: 543.8 bits: 108.8 E(85289): 1.5e-23 Smith-Waterman score: 1103; 56.2% identity (78.2% similar) in 308 aa overlap (2-302:30-325) 10 20 30 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGT : :: :::::::. .:....:: ::: .:: NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 LTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPG ::::::. .::::::: ::::::: :::.:::: : :: ::: .:: :::::::::..:: NP_001 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 AHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAA :: :::.::::.: :. : .: ..: ..: .: :.. :.::::::::.:: :..::.. NP_001 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 DKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLS :: .: :.: :.:: :::::. :... :.: :. .::: .: ::::. .: . NP_001 DKIVVQKYHTINGHNCEVKKALSKQEMQSAG----SQRGRGGGSGNFMGRGGNFGGGGGN 190 200 210 220 230 220 230 240 250 260 pF1KE0 KGGGGGYNSYGGYGGGGGGGYNAYGGGGGG-SSYGGS-DYGNG--FGGFGSYS-QHQSSY : ::.... :::::::::. ..:::: :: ...::. .::.: .. ::.:: :.::.: NP_001 FGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGNYGGGGNYNDFGNYSGQQQSNY 240 250 260 270 280 290 270 280 290 300 pF1KE0 GPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSSF ::::.: :.::::...:: ::::.::: :: NP_001 GPMKGG--------SFGGRSSGSPYGGGYGSGGGSGGYGSRRF 300 310 320 330 >>NP_001317180 (OMIM: 605372) heterogeneous nuclear ribo (331 aa) initn: 1292 init1: 887 opt: 1103 Z-score: 543.8 bits: 108.8 E(85289): 1.5e-23 Smith-Waterman score: 1103; 56.2% identity (78.2% similar) in 308 aa overlap (2-302:30-325) 10 20 30 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGT : :: :::::::. .:....:: ::: .:: NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 LTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPG ::::::. .::::::: ::::::: :::.:::: : :: ::: .:: :::::::::..:: NP_001 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 AHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAA :: :::.::::.: :. : .: ..: ..: .: :.. :.::::::::.:: :..::.. NP_001 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 DKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLS :: .: :.: :.:: :::::. :... :.: :. .::: .: ::::. .: . NP_001 DKIVVQKYHTINGHNCEVKKALSKQEMQSAG----SQRGRGGGSGNFMGRGGNFGGGGGN 190 200 210 220 230 220 230 240 250 260 pF1KE0 KGGGGGYNSYGGYGGGGGGGYNAYGGGGGG-SSYGGS-DYGNG--FGGFGSYS-QHQSSY : ::.... :::::::::. ..:::: :: ...::. .::.: .. ::.:: :.::.: NP_001 FGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGNYGGGGNYNDFGNYSGQQQSNY 240 250 260 270 280 290 270 280 290 300 pF1KE0 GPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSSF ::::.: :.::::...:: ::::.::: :: NP_001 GPMKGG--------SFGGRSSGSPYGGGYGSGGGSGGYGSRRF 300 310 320 330 >>NP_001317176 (OMIM: 605372) heterogeneous nuclear ribo (356 aa) initn: 1429 init1: 934 opt: 1046 Z-score: 517.1 bits: 104.0 E(85289): 4.6e-22 Smith-Waterman score: 1046; 54.2% identity (76.1% similar) in 306 aa overlap (2-300:8-307) 10 20 30 40 50 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVT : :: :::::::. .:....:: ::: .::::::::. .::::::: ::::: NP_001 MEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 YSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDL :: :::.:::: : :: ::: .:: :::::::::..:::: :::.::::.: :. : .: NP_001 YSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 IEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAV ..: ..: .: :.. :.::::::::.:: :..::..:: .: :.: :.:: :::::. NP_001 RDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKAL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 PKEDIYSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYN :... :.: :. .::: .: ::::. .: . : ::.... :::::::::. . NP_001 SKQEMQSAG----SQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRG 190 200 210 220 230 240 250 260 270 280 pF1KE0 AYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSG----GGGGGGGSSWGGRSNSG .:::: :: . :.: :: .:: .::. ...:: : ::: :::... : ...: NP_001 SYGGGDGGYNGFGGDGGN-YGGGPGYSS-RGGYGGGGPGYGNQGGGYGGGGGYDGYNEGG 240 250 260 270 280 290 290 300 pF1KE0 PYRGG-YGGGGGYGGSSF . :: :::::.: NP_001 NFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSR 300 310 320 330 340 350 >>NP_001317177 (OMIM: 605372) heterogeneous nuclear ribo (356 aa) initn: 1429 init1: 934 opt: 1046 Z-score: 517.1 bits: 104.0 E(85289): 4.6e-22 Smith-Waterman score: 1046; 54.2% identity (76.1% similar) in 306 aa overlap (2-300:8-307) 10 20 30 40 50 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVT : :: :::::::. .:....:: ::: .::::::::. .::::::: ::::: NP_001 MEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 YSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDL :: :::.:::: : :: ::: .:: :::::::::..:::: :::.::::.: :. : .: NP_001 YSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 IEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAV ..: ..: .: :.. :.::::::::.:: :..::..:: .: :.: :.:: :::::. NP_001 RDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKAL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 PKEDIYSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYN :... :.: :. .::: .: ::::. .: . : ::.... :::::::::. . NP_001 SKQEMQSAG----SQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRG 190 200 210 220 230 240 250 260 270 280 pF1KE0 AYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSG----GGGGGGGSSWGGRSNSG .:::: :: . :.: :: .:: .::. ...:: : ::: :::... : ...: NP_001 SYGGGDGGYNGFGGDGGN-YGGGPGYSS-RGGYGGGGPGYGNQGGGYGGGGGYDGYNEGG 240 250 260 270 280 290 290 300 pF1KE0 PYRGG-YGGGGGYGGSSF . :: :::::.: NP_001 NFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSR 300 310 320 330 340 350 >>NP_919223 (OMIM: 605372) heterogeneous nuclear ribonuc (378 aa) initn: 1429 init1: 934 opt: 1046 Z-score: 516.9 bits: 104.0 E(85289): 4.7e-22 Smith-Waterman score: 1046; 54.2% identity (76.1% similar) in 306 aa overlap (2-300:30-329) 10 20 30 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGT : :: :::::::. .:....:: ::: .:: NP_919 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 LTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPG ::::::. .::::::: ::::::: :::.:::: : :: ::: .:: :::::::::..:: NP_919 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 AHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAA :: :::.::::.: :. : .: ..: ..: .: :.. :.::::::::.:: :..::.. NP_919 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 DKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLS :: .: :.: :.:: :::::. :... :.: :. .::: .: ::::. .: . NP_919 DKIVVQKYHTINGHNCEVKKALSKQEMQSAG----SQRGRGGGSGNFMGRGGNFGGGGGN 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 KGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKS : ::.... :::::::::. ..:::: :: . :.: :: .:: .::. ...:: NP_919 FGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGN-YGGGPGYSS-RGGYGGGGP 240 250 260 270 280 290 280 290 300 pF1KE0 G----GGGGGGGSSWGGRSNSGPYRGG-YGGGGGYGGSSF : ::: :::... : ...: . :: :::::.: NP_919 GYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGR 300 310 320 330 340 350 NP_919 SSGSPYGGGYGSGGGSGGYGSRRF 360 370 >>NP_001317178 (OMIM: 605372) heterogeneous nuclear ribo (378 aa) initn: 1429 init1: 934 opt: 1046 Z-score: 516.9 bits: 104.0 E(85289): 4.7e-22 Smith-Waterman score: 1046; 54.2% identity (76.1% similar) in 306 aa overlap (2-300:30-329) 10 20 30 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGT : :: :::::::. .:....:: ::: .:: NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 LTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPG ::::::. .::::::: ::::::: :::.:::: : :: ::: .:: :::::::::..:: NP_001 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 AHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAA :: :::.::::.: :. : .: ..: ..: .: :.. :.::::::::.:: :..::.. NP_001 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 DKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLS :: .: :.: :.:: :::::. :... :.: :. .::: .: ::::. .: . NP_001 DKIVVQKYHTINGHNCEVKKALSKQEMQSAG----SQRGRGGGSGNFMGRGGNFGGGGGN 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 KGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKS : ::.... :::::::::. ..:::: :: . :.: :: .:: .::. ...:: NP_001 FGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGN-YGGGPGYSS-RGGYGGGGP 240 250 260 270 280 290 280 290 300 pF1KE0 G----GGGGGGGSSWGGRSNSGPYRGG-YGGGGGYGGSSF : ::: :::... : ...: . :: :::::.: NP_001 GYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGR 300 310 320 330 340 350 NP_001 SSGSPYGGGYGSGGGSGGYGSRRF 360 370 >>NP_002127 (OMIM: 164017,615424,615426) heterogeneous n (320 aa) initn: 828 init1: 828 opt: 1021 Z-score: 505.9 bits: 101.8 E(85289): 1.9e-21 Smith-Waterman score: 1021; 52.0% identity (77.5% similar) in 306 aa overlap (2-304:9-309) 10 20 30 40 50 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFV : :: :::::::. .:.. .::.::: .::::::::. .:.::::: :::: NP_002 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 TYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGD ::..:::.:::: : :: ::: .:: ::::::::: ::::: :::.::::.: :. : NP_002 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 LIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKA : ..: :.: .: ::..:. :::::::.:: :..::..:: .. :.: ..:: ::.:: NP_002 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 VPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGG-GGGGYN . :... :.... .::. :. :: ::::: : . : ::.... ::.::. :::::. NP_002 LSKQEMASASSSQRGRSGSGNFGG-GRGGGFGGND-NFGRGGNFSGRGGFGGSRGGGGYG 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 AYGGGGGGSSYGGSDYGNG--FGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPY . : : .: . ::..:.: .. ::.:....:..::::.:. :: ... .:: .: : NP_002 GSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG---GGQY 240 250 260 270 280 290 300 pF1KE0 RGGYGGGGGYGGSSF . . ::::::: NP_002 FAKPRNQGGYGGSSSSSSYGSGRRF 300 310 320 >>XP_005268883 (OMIM: 164017,615424,615426) PREDICTED: h (372 aa) initn: 1537 init1: 867 opt: 1004 Z-score: 497.5 bits: 100.4 E(85289): 5.6e-21 Smith-Waterman score: 1014; 51.2% identity (70.0% similar) in 340 aa overlap (2-302:9-343) 10 20 30 40 50 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFV : :: :::::::. .:.. .::.::: .::::::::. .:.::::: :::: XP_005 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 TYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGD ::..:::.:::: : :: ::: .:: ::::::::: ::::: :::.::::.: :. : XP_005 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 LIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKA : ..: :.: .: ::..:. :::::::.:: :..::..:: .. :.: ..:: ::.:: XP_005 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA 130 140 150 160 170 180 180 190 200 210 pF1KE0 VPKEDIYSGG----GGGGSRSSRGGRGGR-------GRGG---GRDQNGLSKGGGG---- . :... :.. : .:: . ::::: :::: :: : :.:::: XP_005 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 --GYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGN---GFGGFGSYSQHQSSYGPMKS :::..:. :: :::: .:.::. : . ::. ::: :.:: :::...... : XP_005 GDGYNGFGNDGGYGGGG-PGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGG---- 250 260 270 280 290 280 290 300 pF1KE0 GGGGGGGGSSWGG-------------RSNSGPYRGGYGGG---GGYGGSSF :: :::.::..:: :: ::..:: :: : ::: XP_005 GGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQG 300 310 320 330 340 350 XP_005 GYGGSSSSSSYGSGRRF 360 370 >>NP_112420 (OMIM: 164017,615424,615426) heterogeneous n (372 aa) initn: 1537 init1: 867 opt: 1004 Z-score: 497.5 bits: 100.4 E(85289): 5.6e-21 Smith-Waterman score: 1014; 51.2% identity (70.0% similar) in 340 aa overlap (2-302:9-343) 10 20 30 40 50 pF1KE0 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFV : :: :::::::. .:.. .::.::: .::::::::. .:.::::: :::: NP_112 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 TYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGD ::..:::.:::: : :: ::: .:: ::::::::: ::::: :::.::::.: :. : NP_112 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 LIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKA : ..: :.: .: ::..:. :::::::.:: :..::..:: .. :.: ..:: ::.:: NP_112 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA 130 140 150 160 170 180 180 190 200 210 pF1KE0 VPKEDIYSGG----GGGGSRSSRGGRGGR-------GRGG---GRDQNGLSKGGGG---- . :... :.. : .:: . ::::: :::: :: : :.:::: NP_112 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 --GYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGN---GFGGFGSYSQHQSSYGPMKS :::..:. :: :::: .:.::. : . ::. ::: :.:: :::...... : NP_112 GDGYNGFGNDGGYGGGG-PGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGG---- 250 260 270 280 290 280 290 300 pF1KE0 GGGGGGGGSSWGG-------------RSNSGPYRGGYGGG---GGYGGSSF :: :::.::..:: :: ::..:: :: : ::: NP_112 GGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQG 300 310 320 330 340 350 NP_112 GYGGSSSSSSYGSGRRF 360 370 305 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:57:21 2016 done: Sat Nov 5 02:57:22 2016 Total Scan time: 6.920 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]