Result of FASTA (omim) for
pF1KE0719
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0719, 305 aa
1>>>pF1KE0719 305 - 305 aa - 305 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5430+/-0.000626; mu= -10.5171+/- 0.037
mean_var=628.0199+/-137.623, 0's: 0 Z-trim(115.6): 1789 B-trim: 0 in 0/56
Lambda= 0.051178
statistics sampled from 23556 (26094) to 23556 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.306), width: 16
Scan time: 7.680
The best scores are: opt bits E(85289)
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 2029 165.2 1.5e-40
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 1552 129.9 5.9e-30
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 1320 112.8 8.5e-25
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 1320 112.8 8.5e-25
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 1320 112.8 8.5e-25
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 1216 105.1 1.7e-22
XP_011536034 (OMIM: 116953) PREDICTED: cyclin-depe ( 346) 1085 95.6 1.5e-19
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1082 95.6 2.2e-19
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 1082 95.6 2.2e-19
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1082 95.6 2.2e-19
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1082 95.6 2.2e-19
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1082 95.6 2.2e-19
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1082 95.6 2.2e-19
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1082 95.6 2.2e-19
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1082 95.6 2.2e-19
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1082 95.6 2.2e-19
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1082 95.6 2.2e-19
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 1082 95.6 2.2e-19
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 1082 95.6 2.2e-19
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 1082 95.6 2.3e-19
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 1082 95.6 2.3e-19
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 1082 95.6 2.3e-19
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 1082 95.7 2.3e-19
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 1082 95.7 2.3e-19
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 1079 95.4 2.6e-19
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1079 95.4 2.6e-19
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 1079 95.4 2.6e-19
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1079 95.4 2.6e-19
NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1039 92.4 1.9e-18
NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1039 92.4 1.9e-18
NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1039 92.4 2e-18
XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1039 92.5 2.1e-18
XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1039 92.5 2.1e-18
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1003 89.6 1.1e-17
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1003 89.6 1.1e-17
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1003 89.6 1.1e-17
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1003 89.6 1.1e-17
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1003 89.6 1.1e-17
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 1003 89.6 1.1e-17
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 1003 89.7 1.2e-17
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 1003 89.7 1.2e-17
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 1003 89.7 1.2e-17
NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 1003 89.7 1.2e-17
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 963 86.6 8.4e-17
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 963 86.6 8.4e-17
NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 963 86.7 8.5e-17
XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 963 86.7 8.7e-17
NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 963 86.7 8.9e-17
XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 963 86.7 8.9e-17
NP_001274066 (OMIM: 610679) cyclin-dependent kinas ( 340) 919 83.3 7.4e-16
>>NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 [Ho (305 aa)
initn: 2029 init1: 2029 opt: 2029 Z-score: 849.0 bits: 165.2 E(85289): 1.5e-40
Smith-Waterman score: 2029; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305)
10 20 30 40 50 60
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVL
250 260 270 280 290 300
pF1KE0 QRFRH
:::::
NP_001 QRFRH
>>NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 iso (298 aa)
initn: 1536 init1: 1536 opt: 1552 Z-score: 658.8 bits: 129.9 E(85289): 5.9e-30
Smith-Waterman score: 1552; 76.4% identity (91.2% similar) in 297 aa overlap (1-296:1-297)
10 20 30 40 50 60
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
:. ::::::::::::::::::.:. ::..::::::::: : :::::::::::::::::.:
NP_001 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
::::.::::.:.: ::::::::: :::::.::.. . .:: ::::::::::::..::::
NP_001 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
:::.:::::::::::: :::::::::::::::::.:::::::::::::::::::: :.:
NP_001 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF
.:::::::.::::::::::.::::::::::::::::: ::::.: .:::::..:::: ::
NP_001 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPSPAARQYV
:::.:. . ..:: :. .::.:: :.:.:::..::.::.:::::.:.. .: : :
NP_001 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
250 260 270 280 290
300
pF1KE0 LQRFRH
>>XP_005270360 (OMIM: 116940) PREDICTED: cyclin-dependen (297 aa)
initn: 1310 init1: 898 opt: 1320 Z-score: 566.2 bits: 112.8 E(85289): 8.5e-25
Smith-Waterman score: 1320; 67.0% identity (86.1% similar) in 288 aa overlap (1-287:1-288)
10 20 30 40 50 60
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
:. . :.:::::::::::::.... :::.::.:::::. : :::::::::::::::::.:
XP_005 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCH
:::: : ::. .. .:::.:::::.:::::.:: : :. . :.::::.:.:::. :::
XP_005 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF
:.::.:::::::::::.. :.:::::::::::::.:.:.:::::::::::.::.::::
XP_005 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS
:.: ::::::: ::::..:.: :: ::::::::::::: ::::....:: : .: :::..
XP_005 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYV
:::: .: : ::. .: ::: ..: :::..::..: :: ::::.
XP_005 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
250 260 270 280 290
300
pF1KE0 LQRFRH
>>NP_001307847 (OMIM: 116940) cyclin-dependent kinase 1 (297 aa)
initn: 1310 init1: 898 opt: 1320 Z-score: 566.2 bits: 112.8 E(85289): 8.5e-25
Smith-Waterman score: 1320; 67.0% identity (86.1% similar) in 288 aa overlap (1-287:1-288)
10 20 30 40 50 60
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
:. . :.:::::::::::::.... :::.::.:::::. : :::::::::::::::::.:
NP_001 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCH
:::: : ::. .. .:::.:::::.:::::.:: : :. . :.::::.:.:::. :::
NP_001 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF
:.::.:::::::::::.. :.:::::::::::::.:.:.:::::::::::.::.::::
NP_001 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS
:.: ::::::: ::::..:.: :: ::::::::::::: ::::....:: : .: :::..
NP_001 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYV
:::: .: : ::. .: ::: ..: :::..::..: :: ::::.
NP_001 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
250 260 270 280 290
300
pF1KE0 LQRFRH
>>NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 iso (297 aa)
initn: 1310 init1: 898 opt: 1320 Z-score: 566.2 bits: 112.8 E(85289): 8.5e-25
Smith-Waterman score: 1320; 67.0% identity (86.1% similar) in 288 aa overlap (1-287:1-288)
10 20 30 40 50 60
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
:. . :.:::::::::::::.... :::.::.:::::. : :::::::::::::::::.:
NP_001 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCH
:::: : ::. .. .:::.:::::.:::::.:: : :. . :.::::.:.:::. :::
NP_001 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF
:.::.:::::::::::.. :.:::::::::::::.:.:.:::::::::::.::.::::
NP_001 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS
:.: ::::::: ::::..:.: :: ::::::::::::: ::::....:: : .: :::..
NP_001 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYV
:::: .: : ::. .: ::: ..: :::..::..: :: ::::.
NP_001 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
250 260 270 280 290
300
pF1KE0 LQRFRH
>>NP_004926 (OMIM: 123831,616342) cyclin-dependent-like (292 aa)
initn: 585 init1: 585 opt: 1216 Z-score: 524.8 bits: 105.1 E(85289): 1.7e-22
Smith-Waterman score: 1216; 61.4% identity (85.3% similar) in 293 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
:. ..:.:::::::::.:.::::::: ..::::..::: . :::::.:.::: :::::::
NP_004 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
::::: ::.:...:: ::::: .::::::.:: :. : ...::.:::::.:..::::
NP_004 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDP-EIVKSFLFQLLKGLGFCHS
70 80 90 100 110
130 140 150 160 170 180
pF1KE0 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
. :.::::::::::::. : .::::::::::::.:.: :. :::::::: :..:.:.:.:
NP_004 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 TTAVDIWSIGCIFAEMVTR-KALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS
.:..:.:: ::::::... . ::::.. ::: ::::.::::.:. ::..:.:::::
NP_004 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK-P
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 FPKW-TRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQY
.: . . .: ..::.:. :::::..::. .: :::.:. :: :::::. :
NP_004 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
240 250 260 270 280 290
300
pF1KE0 VLQRFRH
>>XP_011536034 (OMIM: 116953) PREDICTED: cyclin-dependen (346 aa)
initn: 1529 init1: 1085 opt: 1085 Z-score: 471.8 bits: 95.6 E(85289): 1.5e-19
Smith-Waterman score: 1437; 67.1% identity (79.3% similar) in 334 aa overlap (1-286:1-334)
10 20 30 40 50 60
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
:. ::::::::::::::::::.:. ::..::::::::: : :::::::::::::::::.:
XP_011 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
::::.::::.:.: ::::::::: :::::.::.. . .:: ::::::::::::..::::
XP_011 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
:::.:::::::::::: :::::::::::::::::.:::::::::::::::::::: :.:
XP_011 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
130 140 150 160 170 180
190
pF1KE0 TTAVDIWSIGCIFAEM--------------------------------------------
.:::::::.:::::::
XP_011 STAVDIWSLGCIFAEMHLVGTQHHARCCGEHRRNGRQSLCPLCSYLEVAASQGWGMTAVS
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE0 ----VTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIV
:::.::::::::::::::::: ::::.: .:::::..:::: :::::.:. . ..:
XP_011 TPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
250 260 270 280 290 300
260 270 280 290 300
pF1KE0 PNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVLQRFRH
: :. .::.:: :.:.:::..::.::.:::::.:
XP_011 PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
310 320 330 340
>>XP_016885061 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 900 init1: 585 opt: 1082 Z-score: 469.1 bits: 95.6 E(85289): 2.2e-19
Smith-Waterman score: 1082; 54.3% identity (82.0% similar) in 289 aa overlap (1-288:162-448)
10 20 30
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLV
.. . :..:.:::::..:::.:.. : .::
XP_016 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE0 ALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKY
:::.:::. : ::.: :::::.::::.::: ::: : :..:.:..: ::::.:..:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE0 MDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLAR
.:. :. . .: .: .:::::.:...:: ..:.::::::::::::: : .:::::::::
XP_016 LDDC-GNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLAR
260 270 280 290 300
160 170 180 190 200 210
pF1KE0 AFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEID
: ..: .::..:::::::: :.::::: :.: .:.:..:::: ::.: . ::::.. .
XP_016 AKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEE
310 320 330 340 350 360
220 230 240 250 260
pF1KE0 QLFRIFRMLGTPSEDTWPGVTQLPDYKG-SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQY
:: :::.::::.:.::::. . ..: ..::. ..: .: :. .: ::: .:::.
XP_016 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQF
370 380 390 400 410 420
270 280 290 300
pF1KE0 DPSQRITAKTALAHPYFSSPEPSPAARQYVLQRFRH
. .::.:. :. ::.: :
XP_016 EGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAF
430 440 450 460 470 480
>>NP_006192 (OMIM: 311550) cyclin-dependent kinase 16 is (496 aa)
initn: 900 init1: 585 opt: 1082 Z-score: 469.1 bits: 95.6 E(85289): 2.2e-19
Smith-Waterman score: 1082; 54.3% identity (82.0% similar) in 289 aa overlap (1-288:162-448)
10 20 30
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLV
.. . :..:.:::::..:::.:.. : .::
NP_006 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE0 ALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKY
:::.:::. : ::.: :::::.::::.::: ::: : :..:.:..: ::::.:..:::.:
NP_006 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE0 MDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLAR
.:. :. . .: .: .:::::.:...:: ..:.::::::::::::: : .:::::::::
NP_006 LDDC-GNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLAR
260 270 280 290 300
160 170 180 190 200 210
pF1KE0 AFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEID
: ..: .::..:::::::: :.::::: :.: .:.:..:::: ::.: . ::::.. .
NP_006 AKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEE
310 320 330 340 350 360
220 230 240 250 260
pF1KE0 QLFRIFRMLGTPSEDTWPGVTQLPDYKG-SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQY
:: :::.::::.:.::::. . ..: ..::. ..: .: :. .: ::: .:::.
NP_006 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQF
370 380 390 400 410 420
270 280 290 300
pF1KE0 DPSQRITAKTALAHPYFSSPEPSPAARQYVLQRFRH
. .::.:. :. ::.: :
NP_006 EGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAF
430 440 450 460 470 480
>>XP_016885062 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 900 init1: 585 opt: 1082 Z-score: 469.1 bits: 95.6 E(85289): 2.2e-19
Smith-Waterman score: 1082; 54.3% identity (82.0% similar) in 289 aa overlap (1-288:162-448)
10 20 30
pF1KE0 MDMFQKVEKIGEGTYGVVYKAKNRETGQLV
.. . :..:.:::::..:::.:.. : .::
XP_016 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE0 ALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKY
:::.:::. : ::.: :::::.::::.::: ::: : :..:.:..: ::::.:..:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE0 MDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLAR
.:. :. . .: .: .:::::.:...:: ..:.::::::::::::: : .:::::::::
XP_016 LDDC-GNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLAR
260 270 280 290 300
160 170 180 190 200 210
pF1KE0 AFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEID
: ..: .::..:::::::: :.::::: :.: .:.:..:::: ::.: . ::::.. .
XP_016 AKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEE
310 320 330 340 350 360
220 230 240 250 260
pF1KE0 QLFRIFRMLGTPSEDTWPGVTQLPDYKG-SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQY
:: :::.::::.:.::::. . ..: ..::. ..: .: :. .: ::: .:::.
XP_016 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQF
370 380 390 400 410 420
270 280 290 300
pF1KE0 DPSQRITAKTALAHPYFSSPEPSPAARQYVLQRFRH
. .::.:. :. ::.: :
XP_016 EGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAF
430 440 450 460 470 480
305 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:23:44 2016 done: Sat Nov 5 18:23:45 2016
Total Scan time: 7.680 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]