FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0722, 415 aa 1>>>pF1KE0722 415 - 415 aa - 415 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8644+/-0.000523; mu= -8.5776+/- 0.032 mean_var=431.0419+/-90.585, 0's: 0 Z-trim(117.9): 102 B-trim: 41 in 1/60 Lambda= 0.061775 statistics sampled from 30316 (30422) to 30316 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.357), width: 16 Scan time: 8.540 The best scores are: opt bits E(85289) NP_003969 (OMIM: 604416,606347) proline-serine-thr ( 416) 2738 258.7 2e-68 NP_001308066 (OMIM: 604416,606347) proline-serine- ( 481) 2738 258.7 2.2e-68 NP_001308065 (OMIM: 604416,606347) proline-serine- ( 407) 2652 251.0 4e-66 XP_011520467 (OMIM: 604416,606347) PREDICTED: prol ( 367) 1974 190.5 5.8e-48 XP_011520466 (OMIM: 604416,606347) PREDICTED: prol ( 401) 1974 190.6 6.2e-48 XP_011520470 (OMIM: 604416,606347) PREDICTED: prol ( 435) 1974 190.6 6.5e-48 XP_006720800 (OMIM: 604416,606347) PREDICTED: prol ( 294) 1949 188.2 2.3e-47 XP_011520465 (OMIM: 604416,606347) PREDICTED: prol ( 432) 1943 187.8 4.4e-47 NP_001308064 (OMIM: 604416,606347) proline-serine- ( 397) 1832 177.9 3.9e-44 XP_011520468 (OMIM: 604416,606347) PREDICTED: prol ( 358) 1063 109.3 1.6e-23 XP_011520469 (OMIM: 604416,606347) PREDICTED: prol ( 319) 1059 108.9 1.9e-23 NP_077748 (OMIM: 616046) proline-serine-threonine ( 334) 969 100.9 5e-21 XP_011520471 (OMIM: 604416,606347) PREDICTED: prol ( 284) 852 90.4 6.2e-18 XP_011524558 (OMIM: 616046) PREDICTED: proline-ser ( 282) 748 81.1 3.8e-15 XP_011524555 (OMIM: 616046) PREDICTED: proline-ser ( 308) 748 81.2 4e-15 XP_011524556 (OMIM: 616046) PREDICTED: proline-ser ( 301) 666 73.8 6.3e-13 NP_003635 (OMIM: 603127) growth arrest-specific pr ( 336) 299 41.2 0.0047 XP_016880731 (OMIM: 603127) PREDICTED: growth arre ( 353) 299 41.2 0.0049 XP_005256891 (OMIM: 603127) PREDICTED: growth arre ( 353) 299 41.2 0.0049 XP_005256892 (OMIM: 603127) PREDICTED: growth arre ( 353) 299 41.2 0.0049 XP_005256890 (OMIM: 603127) PREDICTED: growth arre ( 353) 299 41.2 0.0049 XP_016880730 (OMIM: 603127) PREDICTED: growth arre ( 389) 299 41.3 0.0052 XP_016880729 (OMIM: 603127) PREDICTED: growth arre ( 397) 299 41.3 0.0053 XP_016880728 (OMIM: 603127) PREDICTED: growth arre ( 412) 299 41.3 0.0054 XP_005256889 (OMIM: 603127) PREDICTED: growth arre ( 412) 299 41.3 0.0054 XP_005256888 (OMIM: 603127) PREDICTED: growth arre ( 412) 299 41.3 0.0054 NP_001124303 (OMIM: 603127) growth arrest-specific ( 412) 299 41.3 0.0054 XP_011522346 (OMIM: 603127) PREDICTED: growth arre ( 412) 299 41.3 0.0054 NP_958836 (OMIM: 603127) growth arrest-specific pr ( 416) 299 41.3 0.0055 NP_958839 (OMIM: 603127) growth arrest-specific pr ( 476) 299 41.4 0.006 >>NP_003969 (OMIM: 604416,606347) proline-serine-threoni (416 aa) initn: 2738 init1: 2738 opt: 2738 Z-score: 1349.4 bits: 258.7 E(85289): 2e-68 Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 415 aa overlap (1-415:2-416) 10 20 30 40 50 pF1KE0 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 IQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE0 AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 370 380 390 400 410 >>NP_001308066 (OMIM: 604416,606347) proline-serine-thre (481 aa) initn: 2738 init1: 2738 opt: 2738 Z-score: 1348.6 bits: 258.7 E(85289): 2.2e-68 Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 415 aa overlap (1-415:67-481) 10 20 30 pF1KE0 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLD :::::::::::::::::::::::::::::: NP_001 GLGRCCWRLALHQASLWQESELCRGRRLRMMPQLQFKDAFWCRDFTAHTGYEVLLQRLLD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 GRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSLKQQMENVGSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSLKQQMENVGSSH 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 IQLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDA 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 DDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRT 220 230 240 250 260 270 220 230 240 250 260 270 pF1KE0 TCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQA 280 290 300 310 320 330 280 290 300 310 320 330 pF1KE0 KSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAAST 340 350 360 370 380 390 340 350 360 370 380 390 pF1KE0 ETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILE 400 410 420 430 440 450 400 410 pF1KE0 GEDGWWTVERNGQRGFVPGSYLEKL ::::::::::::::::::::::::: NP_001 GEDGWWTVERNGQRGFVPGSYLEKL 460 470 480 >>NP_001308065 (OMIM: 604416,606347) proline-serine-thre (407 aa) initn: 2652 init1: 2652 opt: 2652 Z-score: 1308.1 bits: 251.0 E(85289): 4e-66 Smith-Waterman score: 2652; 100.0% identity (100.0% similar) in 404 aa overlap (12-415:4-407) 10 20 30 40 50 60 pF1KE0 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVQCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 RKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYEA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 VMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 DSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 CVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 QPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPA 300 310 320 330 340 350 370 380 390 400 410 pF1KE0 QEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 360 370 380 390 400 >>XP_011520467 (OMIM: 604416,606347) PREDICTED: proline- (367 aa) initn: 1974 init1: 1974 opt: 1974 Z-score: 982.1 bits: 190.5 E(85289): 5.8e-48 Smith-Waterman score: 2215; 94.5% identity (94.8% similar) in 365 aa overlap (70-415:3-367) 40 50 60 70 80 90 pF1KE0 ELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLRE .::::::::::::::::::::::::::::: XP_011 MPSSLRASFDSLKQQMENVGSSHIQLALTLRE 10 20 30 100 110 120 130 140 pF1KE0 ELRSLEEFRERQKEQRKK-------------------YEAVMDRVQKSKLSLYKKAMESK :::::::::::::::::: ::::::::::::::::::::::: XP_011 ELRSLEEFRERQKEQRKKGMAVPRQSDCMEVKSPSWEYEAVMDRVQKSKLSLYKKAMESK 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 KTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKV 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 RAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSI 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 DADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKT 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE0 TSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLS 280 290 300 310 320 330 390 400 410 pF1KE0 AGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL ::::::::::::::::::::::::::::::::::: XP_011 AGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 340 350 360 >>XP_011520466 (OMIM: 604416,606347) PREDICTED: proline- (401 aa) initn: 1974 init1: 1974 opt: 1974 Z-score: 981.6 bits: 190.6 E(85289): 6.2e-48 Smith-Waterman score: 2453; 95.3% identity (95.3% similar) in 401 aa overlap (34-415:1-401) 10 20 30 40 50 60 pF1KE0 LQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKA :::::::::::::::::::::::::::::: XP_011 MCKDMEELLRQRAQAEERYGKELVQIARKA 10 20 30 70 80 90 100 110 pF1KE0 GGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKK------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKGMAVPR 40 50 60 70 80 90 120 130 140 150 160 pF1KE0 -------------YEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANG ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSDCMEVKSPSWEYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANG 100 110 120 130 140 150 170 180 190 200 210 220 pF1KE0 HQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLT 160 170 180 190 200 210 230 240 250 260 270 280 pF1KE0 ILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQ 220 230 240 250 260 270 290 300 310 320 330 340 pF1KE0 NYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVY 280 290 300 310 320 330 350 360 370 380 390 400 pF1KE0 TAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQR 340 350 360 370 380 390 410 pF1KE0 GFVPGSYLEKL ::::::::::: XP_011 GFVPGSYLEKL 400 >>XP_011520470 (OMIM: 604416,606347) PREDICTED: proline- (435 aa) initn: 1974 init1: 1974 opt: 1974 Z-score: 981.2 bits: 190.6 E(85289): 6.5e-48 Smith-Waterman score: 2690; 95.6% identity (95.6% similar) in 434 aa overlap (1-415:2-435) 10 20 30 40 50 pF1KE0 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKK-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKGM 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 -----------------YEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERI ::::::::::::::::::::::::::::::::::::::::::: XP_011 AVPRQSDCMEVKSPSWEYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEF 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 DRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 VPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE0 EGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVER 370 380 390 400 410 420 410 pF1KE0 NGQRGFVPGSYLEKL ::::::::::::::: XP_011 NGQRGFVPGSYLEKL 430 >>XP_006720800 (OMIM: 604416,606347) PREDICTED: proline- (294 aa) initn: 1949 init1: 1949 opt: 1949 Z-score: 971.2 bits: 188.2 E(85289): 2.3e-47 Smith-Waterman score: 1949; 100.0% identity (100.0% similar) in 294 aa overlap (122-415:1-294) 100 110 120 130 140 150 pF1KE0 QLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDAD :::::::::::::::::::::::::::::: XP_006 MDRVQKSKLSLYKKAMESKKTYEQKCRDAD 10 20 30 160 170 180 190 200 210 pF1KE0 DAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTT 40 50 60 70 80 90 220 230 240 250 260 270 pF1KE0 CEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAK 100 110 120 130 140 150 280 290 300 310 320 330 pF1KE0 STGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTE 160 170 180 190 200 210 340 350 360 370 380 390 pF1KE0 TLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEG 220 230 240 250 260 270 400 410 pF1KE0 EDGWWTVERNGQRGFVPGSYLEKL :::::::::::::::::::::::: XP_006 EDGWWTVERNGQRGFVPGSYLEKL 280 290 >>XP_011520465 (OMIM: 604416,606347) PREDICTED: proline- (432 aa) initn: 1392 init1: 1392 opt: 1943 Z-score: 966.3 bits: 187.8 E(85289): 4.4e-47 Smith-Waterman score: 2659; 94.9% identity (94.9% similar) in 434 aa overlap (1-415:2-432) 10 20 30 40 50 pF1KE0 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKK-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKGM 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 -----------------YEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERI ::::::::::::::::::::::::::::::::::::::::::: XP_011 AVPRQSDCMEVKSPSWEYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEF 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 DRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 VPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERN ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 VPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASA---ETLTPTPERN 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 EGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVER 360 370 380 390 400 410 410 pF1KE0 NGQRGFVPGSYLEKL ::::::::::::::: XP_011 NGQRGFVPGSYLEKL 420 430 >>NP_001308064 (OMIM: 604416,606347) proline-serine-thre (397 aa) initn: 2539 init1: 1827 opt: 1832 Z-score: 913.3 bits: 177.9 E(85289): 3.9e-44 Smith-Waterman score: 2477; 93.5% identity (94.7% similar) in 415 aa overlap (1-415:2-397) 10 20 30 40 50 pF1KE0 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG :::::::::::::::::::::::::::::::::::::::. : :..: . NP_001 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPGEVR-----------LADSAA 250 260 270 280 300 310 320 330 340 350 pF1KE0 IQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP .::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 --------SRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP 290 300 310 320 330 340 360 370 380 390 400 410 pF1KE0 AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 350 360 370 380 390 >>XP_011520468 (OMIM: 604416,606347) PREDICTED: proline- (358 aa) initn: 1846 init1: 1062 opt: 1063 Z-score: 543.4 bits: 109.3 E(85289): 1.6e-23 Smith-Waterman score: 1779; 93.0% identity (93.3% similar) in 300 aa overlap (1-281:2-301) 10 20 30 40 50 pF1KE0 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKK-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKGM 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 -----------------YEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERI ::::::::::::::::::::::::::::::::::::::::::: XP_011 AVPRQSDCMEVKSPSWEYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEF 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 DRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 DRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPGE 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 VPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERN : XP_011 VRLADSAASSSGALPELLRSGGHPADQQPWHTAVLRHDKEVLWTAARKSQDHFVGSFC 310 320 330 340 350 415 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:58:37 2016 done: Sat Nov 5 02:58:38 2016 Total Scan time: 8.540 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]