Result of FASTA (ccds) for
pF1KE0736
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0736, 423 aa
1>>>pF1KE0736 423 - 423 aa - 423 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4046+/-0.000881; mu= 0.0736+/- 0.053
mean_var=238.7288+/-49.550, 0's: 0 Z-trim(115.1): 59 B-trim: 0 in 0/53
Lambda= 0.083008
statistics sampled from 15556 (15609) to 15556 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.479), width: 16
Scan time: 2.710
The best scores are: opt bits E(32554)
CCDS10120.2 SHF gene_id:90525|Hs108|chr15 ( 423) 2919 362.1 5.8e-100
CCDS73721.1 SHF gene_id:90525|Hs108|chr15 ( 239) 1079 141.6 8e-34
CCDS76750.1 SHF gene_id:90525|Hs108|chr15 ( 367) 818 110.4 2.9e-24
CCDS76749.1 SHF gene_id:90525|Hs108|chr15 ( 290) 805 108.8 7e-24
CCDS43806.1 SHB gene_id:6461|Hs108|chr9 ( 509) 708 97.4 3.4e-20
CCDS30877.1 SHE gene_id:126669|Hs108|chr1 ( 495) 544 77.7 2.7e-14
CCDS12125.1 SHD gene_id:56961|Hs108|chr19 ( 340) 535 76.5 4.3e-14
>>CCDS10120.2 SHF gene_id:90525|Hs108|chr15 (423 aa)
initn: 2919 init1: 2919 opt: 2919 Z-score: 1908.1 bits: 362.1 E(32554): 5.8e-100
Smith-Waterman score: 2919; 99.8% identity (99.8% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KE0 MQQEGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MQQEGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EPISSSPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EPISSSPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
CCDS10 SAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATAEGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAI
370 380 390 400 410 420
pF1KE0 RTL
:::
CCDS10 RTL
>>CCDS73721.1 SHF gene_id:90525|Hs108|chr15 (239 aa)
initn: 1071 init1: 1071 opt: 1079 Z-score: 720.7 bits: 141.6 E(32554): 8e-34
Smith-Waterman score: 1530; 83.2% identity (83.2% similar) in 286 aa overlap (138-423:1-239)
110 120 130 140 150 160
pF1KE0 YADPFDVQETGEGSAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTP
::::::::::::::::::::::::::::::
CCDS73 MEPYEAQKMMAEIRGSKETATQPLPLYDTP
10 20 30
170 180 190 200 210 220
pF1KE0 YEPEEDGATPEGEGAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLP
::::::::: ::::::::::::::::::::::::::::::::::::::::
CCDS73 YEPEEDGATAEGEGAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFA----------
40 50 60 70 80
230 240 250 260 270 280
pF1KE0 WPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPP
:::::::::::::::::::::::
CCDS73 -------------------------------------AQFEGPEKSCLSPGREEKGRLPP
90 100
290 300 310 320 330 340
pF1KE0 RLSAGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RLSAGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLV
110 120 130 140 150 160
350 360 370 380 390 400
pF1KE0 RNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIK
170 180 190 200 210 220
410 420
pF1KE0 GAEHMSLLYPVAIRTL
::::::::::::::::
CCDS73 GAEHMSLLYPVAIRTL
230
>>CCDS76750.1 SHF gene_id:90525|Hs108|chr15 (367 aa)
initn: 1269 init1: 806 opt: 818 Z-score: 549.2 bits: 110.4 E(32554): 2.9e-24
Smith-Waterman score: 1125; 64.9% identity (69.8% similar) in 291 aa overlap (36-326:115-344)
10 20 30 40 50 60
pF1KE0 GPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHREPISS
:: . : : . :: : .. ::
CCDS76 APPAPPPDILAAYRLQRERDFEDPYSGGSSGSAALATPVAPGPTPPPRHGSPPHRLIRVE
90 100 110 120 130 140
70 80 90 100 110 120
pF1KE0 SPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEGSAGAS
.: : : : ... :. ... ::: :::::::::::::::::::::::
CCDS76 TPGPPAP-PADERISGPPASS--------DRL-----AILEDYADPFDVQETGEGSAGAS
150 160 170 180 190
130 140 150 160 170 180
pF1KE0 GAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGEGAPWP
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
CCDS76 GAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATAEGEGAPWP
200 210 220 230 240 250
190 200 210 220 230 240
pF1KE0 RESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGD
::::::::::::::::::::::::::::::::
CCDS76 RESRLPEDDERPPEEYDQPWEWKKERISKAFA----------------------------
260 270 280
250 260 270 280 290 300
pF1KE0 RDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPLSMEPS
:::::::::::::::::::::::::::::::::::::::::
CCDS76 -------------------AQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPLSMEPS
290 300 310 320
310 320 330 340 350 360
pF1KE0 SPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQ
::::::::::::::::. .:
CCDS76 SPLGEWTDPALPLENQLVSRGHQPNRRREPAPAVQRGQLPGAQQ
330 340 350 360
>>CCDS76749.1 SHF gene_id:90525|Hs108|chr15 (290 aa)
initn: 805 init1: 805 opt: 805 Z-score: 542.2 bits: 108.8 E(32554): 7e-24
Smith-Waterman score: 824; 72.0% identity (78.6% similar) in 182 aa overlap (36-217:115-282)
10 20 30 40 50 60
pF1KE0 GPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHREPISS
:: . : : . :: : .. ::
CCDS76 APPAPPPDILAAYRLQRERDFEDPYSGGSSGSAALATPVAPGPTPPPRHGSPPHRLIRVE
90 100 110 120 130 140
70 80 90 100 110 120
pF1KE0 SPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEGSAGAS
.: : : : ... :. ... ::: :::::::::::::::::::::::
CCDS76 TPGPPAP-PADERISGPPASS--------DRL-----AILEDYADPFDVQETGEGSAGAS
150 160 170 180 190
130 140 150 160 170 180
pF1KE0 GAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGEGAPWP
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
CCDS76 GAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATAEGEGAPWP
200 210 220 230 240 250
190 200 210 220 230 240
pF1KE0 RESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGD
::::::::::::::::::::::::::::::::
CCDS76 RESRLPEDDERPPEEYDQPWEWKKERISKAFAGAARDSCT
260 270 280 290
250 260 270 280 290 300
pF1KE0 RDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPLSMEPS
>>CCDS43806.1 SHB gene_id:6461|Hs108|chr9 (509 aa)
initn: 740 init1: 436 opt: 708 Z-score: 476.0 bits: 97.4 E(32554): 3.4e-20
Smith-Waterman score: 961; 44.1% identity (65.7% similar) in 408 aa overlap (22-423:169-509)
10 20 30 40 50
pF1KE0 MQQEGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPS
: ..:.. . ::: : ... . . .
CCDS43 CCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGGGAGD
140 150 160 170 180 190
60 70 80 90 100 110
pF1KE0 PLNSHCAHREPISSSPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADP
::.. :: . : :.: : :. .. :... .:.. .: .::.::
CCDS43 PLGGACAGGRTWS----PTACGGKKLLNKCAASAAEESGAGKKDKV-----TIADDYSDP
200 210 220 230 240
120 130 140 150 160
pF1KE0 FDVQETGEGSAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQP--LPLYDTPYE
::... ...:: . :. :::::::::..:.:.. .. . .: . :::::::
CCDS43 FDAKNDLKSKAGKG-------ESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYE
250 260 270 280 290 300
170 180 190 200 210 220
pF1KE0 PEEDGATPEGEG--APWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLP
:: ... ..:. .: :::.::.::.:: .::::::::.. :
CCDS43 PEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTI---------------
310 320 330 340
230 240 250 260 270 280
pF1KE0 WPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGPEK--SCLSPGREEKGRL
:.: .:::.: :: : ::.:... .:
CCDS43 -----------PAL----------------------AAQFNGNEKRQSSPSPSRDRRRQL
350 360 370
290 300 310 320 330 340
pF1KE0 PPRLSAGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASY
: .:. : : : : . ::: .:::.:::.:.:::::::: ::::::::::: ::
CCDS43 --RAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSY
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE0 LVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLP
:::::.:::.:.::::.:.::::::::..::: :::::::::::.::::..:.:..::::
CCDS43 LVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKE-KYVLGQNSPPFDSVPEVIHYYTTRKLP
440 450 460 470 480 490
410 420
pF1KE0 IKGAEHMSLLYPVAIRTL
::::::.:::::::.:::
CCDS43 IKGAEHLSLLYPVAVRTL
500
>>CCDS30877.1 SHE gene_id:126669|Hs108|chr1 (495 aa)
initn: 885 init1: 468 opt: 544 Z-score: 370.0 bits: 77.7 E(32554): 2.7e-14
Smith-Waterman score: 781; 40.3% identity (58.2% similar) in 404 aa overlap (50-418:162-490)
20 30 40 50 60 70
pF1KE0 GSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHREPISSSPQPVANGPKQKKK
:: .: . ::::. . ::. :
CCDS30 RGATKSSGCSTYINRLIKVDTQEKNGKSNYPSSSSSSSSSSSSASSSPSSL--GPELDKG
140 150 160 170 180
80 90 100 110 120 130
pF1KE0 SNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEGSAGASGAPEKVPENDGYME
.::. .. . ::::::::.:...: .:. : :.: :::::::
CCDS30 ---------KIIKQQETV-----IILEDYADPYDAKRT-KGQRDA----ERVGENDGYME
190 200 210 220 230
140 150 160
pF1KE0 PYEAQKMMAEIR--GSKET---ATQ------------------------------PLPLY
::.::.:..::: :::. : : : ::
CCDS30 PYDAQQMITEIRRRGSKDPLVKALQLLDSPCEPADGGLKSETLAKRRSSKDLLGKPPQLY
240 250 260 270 280 290
170 180 190 200 210 220
pF1KE0 DTPYEPEEDGATPEGEGAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIK
:::::: : : :..:: : .:::::.:::: ::.::::::::.: .:..:
CCDS30 DTPYEPAEGG--PRAEGKARPPDSRLPENDERPAAEYEQPWEWKKEQIVRALSV------
300 310 320 330 340
230 240 250 260 270 280
pF1KE0 DLPWPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGR
:::: :. . ::: :
CCDS30 -----------------------------------------QFEGAERPSF---REETVR
350
290 300 310 320 330 340
pF1KE0 LPPRLSAGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEAS
: .. . : :: . : :: .::.::::.: ::::::::..::. :. ::::.
CCDS30 QHHRQKSWTQKILKPALSDHSE--GEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAG
360 370 380 390 400 410
350 360 370 380 390 400
pF1KE0 YLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKL
:::::::.... .:..::.::: .:. ...::..::.:.:.: :.:.::.::.:...::
CCDS30 YLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKL
420 430 440 450 460 470
410 420
pF1KE0 PIKGAEHMSLLYPVAIRTL
:.::::::.:::::
CCDS30 PFKGAEHMTLLYPVHSKLH
480 490
>>CCDS12125.1 SHD gene_id:56961|Hs108|chr19 (340 aa)
initn: 876 init1: 507 opt: 535 Z-score: 366.5 bits: 76.5 E(32554): 4.3e-14
Smith-Waterman score: 806; 40.9% identity (60.8% similar) in 367 aa overlap (67-422:55-339)
40 50 60 70 80 90
pF1KE0 SLSSAQPHSWMLTPSPLNSHCAHREPISSSPQPVANGPKQKKKSNWRSTTRLRIIRLRDR
:.:.. : ... . .. . :.:...
CCDS12 YTESDILRAYRAQKNLDFEDPYEDAESRLEPDPAGPGDSKNPGDAKYGSPKHRLIKVEAA
30 40 50 60 70 80
100 110 120 130 140
pF1KE0 LEPRPLAIL----------EDYADPFDVQETGEGSAGASGAPEKVPENDGYMEPYEAQKM
: :.: .: ::::.: :. .: .:::::::.:: .
CCDS12 DMARAKALLGGPGEELEADTEYLDPFDAQ------------PHPAPPDDGYMEPYDAQWV
90 100 110 120 130
150 160 170 180 190 200
pF1KE0 MAEIRGSKETATQPLPLYDTPYEPEEDGATPEGEGAPW-PRESRLPEDDERPPEEYDQPW
:.:. : . . ::::::: :.: : .: . ::.::.:..:::: .::::::
CCDS12 MSELPG------RGVQLYDTPYE-EQDPETADGPPSGQKPRQSRMPQEDERPADEYDQPW
140 150 160 170 180
210 220 230 240 250 260
pF1KE0 EWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSA
::::..::.:::: :.:: :. .:
CCDS12 EWKKDHISRAFAV---------------QFDS----PEWER-------------------
190 200
270 280 290 300 310 320
pF1KE0 QFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYH
.:: .. : :: :.: .: .: .:::::::.: :.:
CCDS12 ----------TPGSAKELRRPP------PRSPQP---------AERVDPALPLEKQPWFH
210 220 230 240
330 340 350 360 370 380
pF1KE0 GAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQN
: ..:.:::.:: ::::.::::: :::. .: ::::.:::::.:.:..::.:.. ::::.
CCDS12 GPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQVVLGQH
250 260 270 280 290 300
390 400 410 420
pF1KE0 SPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL
: :: ::::.: ::.:: ::..::::..:::::. .:
CCDS12 SGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP
310 320 330 340
423 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:22:21 2016 done: Sat Nov 5 04:22:21 2016
Total Scan time: 2.710 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]