Result of FASTA (omim) for pF1KE0749
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0749, 326 aa
  1>>>pF1KE0749 326 - 326 aa - 326 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.3751+/-0.000524; mu= -26.4202+/- 0.031
 mean_var=689.3934+/-154.246, 0's: 0 Z-trim(117.2): 800  B-trim: 0 in 0/57
 Lambda= 0.048847
 statistics sampled from 27804 (28928) to 27804 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.339), width:  16
 Scan time:  7.620

The best scores are:                                      opt bits E(85289)
NP_001001852 (OMIM: 610580) serine/threonine-prote ( 326) 2224 172.2 1.3e-42
NP_002639 (OMIM: 164960) serine/threonine-protein  ( 313) 1491 120.6 4.5e-27
NP_001230115 (OMIM: 164960) serine/threonine-prote ( 404) 1491 120.7 5.3e-27
NP_006866 (OMIM: 300295) serine/threonine-protein  ( 311) 1197 99.8 7.7e-21
NP_115806 (OMIM: 609235) serine/threonine-protein  ( 778)  527 53.1 2.3e-06
NP_003948 (OMIM: 609236) serine/threonine-protein  ( 668)  476 49.4 2.5e-05
NP_001243558 (OMIM: 609236) serine/threonine-prote ( 674)  476 49.4 2.5e-05
XP_005253275 (OMIM: 609236) PREDICTED: serine/thre ( 720)  476 49.4 2.6e-05
NP_001243556 (OMIM: 609236) serine/threonine-prote ( 736)  476 49.4 2.7e-05
XP_006718437 (OMIM: 609236) PREDICTED: serine/thre ( 758)  476 49.5 2.7e-05
XP_016874025 (OMIM: 609236) PREDICTED: serine/thre ( 858)  476 49.5 2.9e-05
XP_016874022 (OMIM: 609236) PREDICTED: serine/thre ( 880)  476 49.5   3e-05
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661)  468 48.8 3.7e-05
XP_005247048 (OMIM: 607505) PREDICTED: PAS domain- (1107)  471 49.3 4.4e-05
XP_011509134 (OMIM: 607505) PREDICTED: PAS domain- (1137)  471 49.3 4.5e-05
NP_001239051 (OMIM: 607505) PAS domain-containing  (1288)  471 49.4 4.9e-05
XP_016859124 (OMIM: 607505) PREDICTED: PAS domain- (1323)  471 49.4   5e-05
NP_055963 (OMIM: 607505) PAS domain-containing ser (1323)  471 49.4   5e-05
XP_016859125 (OMIM: 607505) PREDICTED: PAS domain- (1323)  471 49.4   5e-05
NP_001239049 (OMIM: 607505) PAS domain-containing  (1323)  471 49.4   5e-05
XP_016859123 (OMIM: 607505) PREDICTED: PAS domain- (1414)  471 49.4 5.2e-05
NP_112214 (OMIM: 608131) NUAK family SNF1-like kin ( 672)  461 48.3 5.2e-05
NP_056006 (OMIM: 608973) serine/threonine-protein  ( 926)  465 48.8 5.3e-05
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765)  460 48.3   6e-05
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765)  460 48.3   6e-05
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765)  460 48.3   6e-05
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373)  446 47.0 7.4e-05
NP_001243559 (OMIM: 609236) serine/threonine-prote ( 766)  451 47.7 9.3e-05
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734)  450 47.6 9.5e-05
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783)  450 47.6 9.9e-05
XP_005259384 (OMIM: 609235) PREDICTED: serine/thre ( 688)  448 47.4  0.0001
XP_011509137 (OMIM: 607505) PREDICTED: PAS domain- ( 873)  451 47.8  0.0001
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610)  446 47.2  0.0001
XP_011516382 (OMIM: 607025) PREDICTED: maternal em ( 622)  446 47.3  0.0001
XP_011509136 (OMIM: 607505) PREDICTED: PAS domain- ( 944)  451 47.8 0.00011
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651)  446 47.3 0.00011
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651)  446 47.3 0.00011
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651)  446 47.3 0.00011
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651)  446 47.3 0.00011
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651)  446 47.3 0.00011
XP_011509135 (OMIM: 607505) PREDICTED: PAS domain- (1114)  451 47.9 0.00012
XP_011509133 (OMIM: 607505) PREDICTED: PAS domain- (1144)  451 47.9 0.00012
XP_011509131 (OMIM: 607505) PREDICTED: PAS domain- (1330)  451 48.0 0.00013
XP_011509132 (OMIM: 607505) PREDICTED: PAS domain- (1330)  451 48.0 0.00013
XP_011509130 (OMIM: 607505) PREDICTED: PAS domain- (1330)  451 48.0 0.00013
NP_001239048 (OMIM: 607505) PAS domain-containing  (1330)  451 48.0 0.00013
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688)  442 47.0 0.00013
XP_011509128 (OMIM: 607505) PREDICTED: PAS domain- (1355)  451 48.0 0.00013
NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752)  442 47.1 0.00014
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709)  441 47.0 0.00014


>>NP_001001852 (OMIM: 610580) serine/threonine-protein k  (326 aa)
 initn: 2224 init1: 2224 opt: 2224  Z-score: 886.0  bits: 172.2 E(85289): 1.3e-42
Smith-Waterman score: 2224; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
              250       260       270       280       290       300

              310       320      
pF1KE0 PESCDLRLCTLDPDDVASTTSSSESL
       ::::::::::::::::::::::::::
NP_001 PESCDLRLCTLDPDDVASTTSSSESL
              310       320      

>>NP_002639 (OMIM: 164960) serine/threonine-protein kina  (313 aa)
 initn: 1421 init1: 1155 opt: 1491  Z-score: 607.1  bits: 120.6 E(85289): 4.5e-27
Smith-Waterman score: 1491; 69.5% identity (87.3% similar) in 315 aa overlap (1-313:1-309)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
       :::::..::::: .    :   .: : :.: .:: .:. :::: .:::::::.::.: :.
NP_002 MLLSKINSLAHLRAAPCNDLHATK-LAPGK-EKEPLESQYQVGPLLGSGGFGSVYSGIRV
               10        20          30        40        50        

               70        80         90       100       110         
pF1KE0 ADGLPVAVKHVVKERVTEWGSL-GGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGF
       .:.::::.::: :.:...:: : .:. ::.:::::.::..  :  :::::::::::::.:
NP_002 SDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--GFSGVIRLLDWFERPDSF
       60        70        80        90         100       110      

     120       130       140       150       160       170         
pF1KE0 LLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVD
       .:.::::::.:::::::::::::.: ::: :: ::: ::::::.:::.::::::::.:.:
NP_002 VLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILID
        120       130       140       150       160       170      

     180       190       200       210       220       230         
pF1KE0 LRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
       :  ::::::::::::::::::::::::::::::::::::::::::::.:::::.::::::
NP_002 LNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMV
        180       190       200       210       220       230      

     240       250       260       270       280       290         
pF1KE0 CGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGG
       :::::::.::::.::...::.::: :::.::::::.::::.::....:  ::::   :  
NP_002 CGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWM--QDVL
        240       250       260       270       280       290      

     300        310       320      
pF1KE0 VP-ESCDLRLCTLDPDDVASTTSSSESL
       .: :. ...: .:.:             
NP_002 LPQETAEIHLHSLSPGPSK         
          300       310            

>>NP_001230115 (OMIM: 164960) serine/threonine-protein k  (404 aa)
 initn: 1421 init1: 1155 opt: 1491  Z-score: 605.8  bits: 120.7 E(85289): 5.3e-27
Smith-Waterman score: 1491; 69.5% identity (87.3% similar) in 315 aa overlap (1-313:92-400)

                                             10        20        30
pF1KE0                               MLLSKFGSLAHLCGPGGVDHLPVKILQPAK
                                     :::::..::::: .    :   .: : :.:
NP_001 PRHSLRHSPGSGSCGSSSGHRPCADILEVGMLLSKINSLAHLRAAPCNDLHATK-LAPGK
              70        80        90       100       110        120

               40        50        60        70        80          
pF1KE0 ADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSL-GGATVPL
        .:: .:. :::: .:::::::.::.: :..:.::::.::: :.:...:: : .:. ::.
NP_001 -EKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPM
               130       140       150       160       170         

      90       100       110       120       130       140         
pF1KE0 EVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARR
       :::::.::..  :  :::::::::::::.:.:.::::::.:::::::::::::.: ::: 
NP_001 EVVLLKKVSS--GFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARS
     180         190       200       210       220       230       

     150       160       170       180       190       200         
pF1KE0 FFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRV
       :: ::: ::::::.:::.::::::::.:.::  :::::::::::::::::::::::::::
NP_001 FFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRV
       240       250       260       270       280       290       

     210       220       230       240       250       260         
pF1KE0 YSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQL
       :::::::::::::::::.:::::.:::::::::::::.::::.::...::.::: :::.:
NP_001 YSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHL
       300       310       320       330       340       350       

     270       280       290       300        310       320      
pF1KE0 IRWCLSLRPSERPSLDQIAAHPWMLGADGGVP-ESCDLRLCTLDPDDVASTTSSSESL
       :::::.::::.::....:  ::::   :  .: :. ...: .:.:             
NP_001 IRWCLALRPSDRPTFEEIQNHPWM--QDVLLPQETAEIHLHSLSPGPSK         
       360       370       380         390       400             

>>NP_006866 (OMIM: 300295) serine/threonine-protein kina  (311 aa)
 initn: 1013 init1: 1013 opt: 1197  Z-score: 495.1  bits: 99.8 E(85289): 7.7e-21
Smith-Waterman score: 1197; 61.9% identity (78.0% similar) in 291 aa overlap (12-301:6-294)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
                  : :: .    :.    :.  :.:.::  :..: .::.::::::.:: :.
NP_006       MLTKPLQGPPAPPGTPTP--PPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRL
                     10          20        30        40        50  

               70        80         90       100       110         
pF1KE0 ADGLPVAVKHVVKERVTEWGSLGGA-TVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGF
       .: : ::.: . ..::  :. :. . : ::::.:: ::::.::  ::::::::::  .::
NP_006 TDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGF
             60        70        80        90       100       110  

     120       130       140       150       160       170         
pF1KE0 LLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVD
       .:::::: :::::::.:::.: : :  .: ::.::.::..:::: :::::::::::.:.:
NP_006 MLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILID
            120       130       140       150       160       170  

     180       190       200       210       220       230         
pF1KE0 LRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
       :: :  :::::::::::.:  ::::::::::::::::  :.::.  :::::::.::::::
NP_006 LRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMV
            180       190       200       210       220       230  

     240       250       260       270       280       290         
pF1KE0 CGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGG
       :::::::.:.:::...: :  .:::.:  ::: ::. .:: ::::..:   :::      
NP_006 CGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAED
            240       250       260       270       280       290  

     300       310       320      
pF1KE0 VPESCDLRLCTLDPDDVASTTSSSESL
       ::                         
NP_006 VPLNPSKGGPAPLAWSLLP        
            300       310         

>>NP_115806 (OMIM: 609235) serine/threonine-protein kina  (778 aa)
 initn: 406 init1: 279 opt: 527  Z-score: 235.3  bits: 53.1 E(85289): 2.3e-06
Smith-Waterman score: 532; 33.3% identity (61.0% similar) in 300 aa overlap (14-304:8-295)

               10          20        30        40        50        
pF1KE0 MLLSKFGSLAHLCGPGGVD--HLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGS
                    : ::    :::    .:   .. ..   :..  .::.:  : :  : 
NP_115       MSSGAKEGGGGSPAYHLPHP--HPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGV
                     10        20          30        40        50  

       60        70        80        90       100       110        
pF1KE0 RIADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDG
       .   :  ::.: : .:...: . :    :  :...:. .        :..: : .:    
NP_115 HCITGQKVAIKIVNREKLSE-SVL--MKVEREIAILKLIEHPH----VLKLHDVYENKKY
             60        70           80        90           100     

      120       130       140       150       160       170        
pF1KE0 FLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLV
       . ::::.   .. :::.....: :    ::.:: :...:.  ::: .. :::.: ::::.
NP_115 LYLVLEHVSGGE-LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL
         110        120       130       140       150       160    

      180       190        200       210       220       230       
pF1KE0 DLRSGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYD
       : ... ... ::: ..: . :..     :.  :. :: :. ..: :: : .:: ::.:. 
NP_115 DEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFA
           170       180       190       200       210       220   

       240             250       260       270       280       290 
pF1KE0 MVCGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHP
       .. : .::..:      :.. :: . . . . :.::.:.:  . ..: .: ::.::  ::
NP_115 LLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHP
           230       240       250       260       270       280   

             300       310       320                               
pF1KE0 WMLGADGGVPESCDLRLCTLDPDDVASTTSSSESL                         
       :.::.    :. :                                               
NP_115 WYLGGKHE-PDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSE
           290        300       310       320       330       340  

>>NP_003948 (OMIM: 609236) serine/threonine-protein kina  (668 aa)
 initn: 289 init1: 289 opt: 476  Z-score: 216.6  bits: 49.4 E(85289): 2.5e-05
Smith-Waterman score: 487; 30.8% identity (60.7% similar) in 308 aa overlap (31-321:10-308)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
                                     :.. ..   :..  .::.:  : :  : . 
NP_003                      MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHC
                                    10        20        30         

               70        80        90       100       110       120
pF1KE0 ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
       .    ::.: : .:...:   .    :  :...:. .        :..: : .:    . 
NP_003 VTCQKVAIKIVNREKLSESVLM---KVEREIAILKLIEHPH----VLKLHDVYENKKYLY
      40        50        60           70            80        90  

              130       140       150       160       170       180
pF1KE0 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
       ::::.   .. :::.....: :    ::.:: :...:.  ::: .. :::.: ::::.: 
NP_003 LVLEHVSGGE-LFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDE
            100        110       120       130       140       150 

              190        200       210       220       230         
pF1KE0 RSGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
       ... ... ::: ..: . :..     :.  :. :: :: ..: ::.: ::: ::.:. ..
NP_003 KNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL
              160       170       180       190       200       210

     240             250       260       270       280       290   
pF1KE0 CGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWM
        : .::..:      :.. :: . . . . :.::.:.:  . .  ..: .:..:  : :.
NP_003 VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
              220       230       240       250       260       270

                 300           310       320                       
pF1KE0 LGA------DGGVPESCDLR----LCTLDPDDVASTTSSSESL                 
       .:.      .  .:.. ..:    :  .::: . :  :                      
NP_003 IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQE
              280       290       300       310       320       330

NP_003 KMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTD
              340       350       360       370       380       390

>>NP_001243558 (OMIM: 609236) serine/threonine-protein k  (674 aa)
 initn: 289 init1: 289 opt: 476  Z-score: 216.6  bits: 49.4 E(85289): 2.5e-05
Smith-Waterman score: 487; 30.8% identity (60.7% similar) in 308 aa overlap (31-321:10-308)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
                                     :.. ..   :..  .::.:  : :  : . 
NP_001                      MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHC
                                    10        20        30         

               70        80        90       100       110       120
pF1KE0 ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
       .    ::.: : .:...:   .    :  :...:. .        :..: : .:    . 
NP_001 VTCQKVAIKIVNREKLSESVLM---KVEREIAILKLIEHPH----VLKLHDVYENKKYLY
      40        50        60           70            80        90  

              130       140       150       160       170       180
pF1KE0 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
       ::::.   .. :::.....: :    ::.:: :...:.  ::: .. :::.: ::::.: 
NP_001 LVLEHVSGGE-LFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDE
            100        110       120       130       140       150 

              190        200       210       220       230         
pF1KE0 RSGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
       ... ... ::: ..: . :..     :.  :. :: :: ..: ::.: ::: ::.:. ..
NP_001 KNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL
              160       170       180       190       200       210

     240             250       260       270       280       290   
pF1KE0 CGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWM
        : .::..:      :.. :: . . . . :.::.:.:  . .  ..: .:..:  : :.
NP_001 VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
              220       230       240       250       260       270

                 300           310       320                       
pF1KE0 LGA------DGGVPESCDLR----LCTLDPDDVASTTSSSESL                 
       .:.      .  .:.. ..:    :  .::: . :  :                      
NP_001 IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQE
              280       290       300       310       320       330

NP_001 KMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTD
              340       350       360       370       380       390

>>XP_005253275 (OMIM: 609236) PREDICTED: serine/threonin  (720 aa)
 initn: 289 init1: 289 opt: 476  Z-score: 216.3  bits: 49.4 E(85289): 2.6e-05
Smith-Waterman score: 487; 30.8% identity (60.7% similar) in 308 aa overlap (31-321:10-308)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
                                     :.. ..   :..  .::.:  : :  : . 
XP_005                      MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHC
                                    10        20        30         

               70        80        90       100       110       120
pF1KE0 ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
       .    ::.: : .:...:   .    :  :...:. .        :..: : .:    . 
XP_005 VTCQKVAIKIVNREKLSESVLM---KVEREIAILKLIEHPH----VLKLHDVYENKKYLY
      40        50        60           70            80        90  

              130       140       150       160       170       180
pF1KE0 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
       ::::.   .. :::.....: :    ::.:: :...:.  ::: .. :::.: ::::.: 
XP_005 LVLEHVSGGE-LFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDE
            100        110       120       130       140       150 

              190        200       210       220       230         
pF1KE0 RSGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
       ... ... ::: ..: . :..     :.  :. :: :: ..: ::.: ::: ::.:. ..
XP_005 KNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL
              160       170       180       190       200       210

     240             250       260       270       280       290   
pF1KE0 CGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWM
        : .::..:      :.. :: . . . . :.::.:.:  . .  ..: .:..:  : :.
XP_005 VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
              220       230       240       250       260       270

                 300           310       320                       
pF1KE0 LGA------DGGVPESCDLR----LCTLDPDDVASTTSSSESL                 
       .:.      .  .:.. ..:    :  .::: . :  :                      
XP_005 IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQE
              280       290       300       310       320       330

XP_005 KMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTD
              340       350       360       370       380       390

>>NP_001243556 (OMIM: 609236) serine/threonine-protein k  (736 aa)
 initn: 289 init1: 289 opt: 476  Z-score: 216.2  bits: 49.4 E(85289): 2.7e-05
Smith-Waterman score: 487; 30.8% identity (60.7% similar) in 308 aa overlap (31-321:10-308)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
                                     :.. ..   :..  .::.:  : :  : . 
NP_001                      MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHC
                                    10        20        30         

               70        80        90       100       110       120
pF1KE0 ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
       .    ::.: : .:...:   .    :  :...:. .        :..: : .:    . 
NP_001 VTCQKVAIKIVNREKLSESVLM---KVEREIAILKLIEHPH----VLKLHDVYENKKYLY
      40        50        60           70            80        90  

              130       140       150       160       170       180
pF1KE0 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
       ::::.   .. :::.....: :    ::.:: :...:.  ::: .. :::.: ::::.: 
NP_001 LVLEHVSGGE-LFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDE
            100        110       120       130       140       150 

              190        200       210       220       230         
pF1KE0 RSGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
       ... ... ::: ..: . :..     :.  :. :: :: ..: ::.: ::: ::.:. ..
NP_001 KNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL
              160       170       180       190       200       210

     240             250       260       270       280       290   
pF1KE0 CGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWM
        : .::..:      :.. :: . . . . :.::.:.:  . .  ..: .:..:  : :.
NP_001 VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
              220       230       240       250       260       270

                 300           310       320                       
pF1KE0 LGA------DGGVPESCDLR----LCTLDPDDVASTTSSSESL                 
       .:.      .  .:.. ..:    :  .::: . :  :                      
NP_001 IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQE
              280       290       300       310       320       330

NP_001 KMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTD
              340       350       360       370       380       390

>>XP_006718437 (OMIM: 609236) PREDICTED: serine/threonin  (758 aa)
 initn: 313 init1: 289 opt: 476  Z-score: 216.0  bits: 49.5 E(85289): 2.7e-05
Smith-Waterman score: 487; 30.8% identity (60.7% similar) in 308 aa overlap (31-321:10-308)

               10        20        30        40        50        60
pF1KE0 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
                                     :.. ..   :..  .::.:  : :  : . 
XP_006                      MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHC
                                    10        20        30         

               70        80        90       100       110       120
pF1KE0 ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
       .    ::.: : .:...:   .    :  :...:. .        :..: : .:    . 
XP_006 VTCQKVAIKIVNREKLSESVLM---KVEREIAILKLIEHPH----VLKLHDVYENKKYLY
      40        50        60           70            80        90  

              130       140       150       160       170       180
pF1KE0 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
       ::::.   .. :::.....: :    ::.:: :...:.  ::: .. :::.: ::::.: 
XP_006 LVLEHVSGGE-LFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDE
            100        110       120       130       140       150 

              190        200       210       220       230         
pF1KE0 RSGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
       ... ... ::: ..: . :..     :.  :. :: :: ..: ::.: ::: ::.:. ..
XP_006 KNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL
              160       170       180       190       200       210

     240             250       260       270       280       290   
pF1KE0 CGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWM
        : .::..:      :.. :: . . . . :.::.:.:  . .  ..: .:..:  : :.
XP_006 VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
              220       230       240       250       260       270

                 300           310       320                       
pF1KE0 LGA------DGGVPESCDLR----LCTLDPDDVASTTSSSESL                 
       .:.      .  .:.. ..:    :  .::: . :  :                      
XP_006 IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQE
              280       290       300       310       320       330

XP_006 KMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTD
              340       350       360       370       380       390




326 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:03:45 2016 done: Sat Nov  5 03:03:47 2016
 Total Scan time:  7.620 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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