FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0753, 338 aa 1>>>pF1KE0753 338 - 338 aa - 338 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.1867+/-0.000793; mu= -11.5483+/- 0.047 mean_var=768.1111+/-182.583, 0's: 0 Z-trim(112.8): 367 B-trim: 424 in 1/53 Lambda= 0.046277 statistics sampled from 21610 (21917) to 21610 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.257), width: 16 Scan time: 7.560 The best scores are: opt bits E(85289) NP_001171668 (OMIM: 610711) testis-specific serine ( 338) 2246 166.0 1.1e-40 XP_011534965 (OMIM: 610711) PREDICTED: testis-spec ( 262) 1758 133.2 6e-31 NP_001294996 (OMIM: 610711) testis-specific serine ( 252) 1238 98.5 1.7e-20 NP_777604 (OMIM: 610711) testis-specific serine/th ( 328) 1238 98.6 1.9e-20 XP_016876715 (OMIM: 610711) PREDICTED: testis-spec ( 291) 969 80.6 4.6e-15 >>NP_001171668 (OMIM: 610711) testis-specific serine/thr (338 aa) initn: 2246 init1: 2246 opt: 2246 Z-score: 851.7 bits: 166.0 E(85289): 1.1e-40 Smith-Waterman score: 2246; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KE0 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKISDFGFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKISDFGFA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 TLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKD 250 260 270 280 290 300 310 320 330 pF1KE0 SWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT :::::::::::::::::::::::::::::::::::::: NP_001 SWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 310 320 330 >>XP_011534965 (OMIM: 610711) PREDICTED: testis-specific (262 aa) initn: 1758 init1: 1758 opt: 1758 Z-score: 676.6 bits: 133.2 E(85289): 6e-31 Smith-Waterman score: 1758; 100.0% identity (100.0% similar) in 262 aa overlap (77-338:1-262) 50 60 70 80 90 100 pF1KE0 QKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQ :::::::::::::::::::::::::::::: XP_011 MKVLRHKYLINFYRAIESTSRVYIILELAQ 10 20 30 110 120 130 140 150 160 pF1KE0 GGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 DKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYN 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE0 PFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLR 160 170 180 190 200 210 290 300 310 320 330 pF1KE0 QATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 220 230 240 250 260 >>NP_001294996 (OMIM: 610711) testis-specific serine/thr (252 aa) initn: 1238 init1: 1238 opt: 1238 Z-score: 489.1 bits: 98.5 E(85289): 1.7e-20 Smith-Waterman score: 1666; 96.2% identity (96.2% similar) in 262 aa overlap (77-338:1-252) 50 60 70 80 90 100 pF1KE0 QKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQ :::::::::::::::::::::::::::::: NP_001 MKVLRHKYLINFYRAIESTSRVYIILELAQ 10 20 30 110 120 130 140 150 160 pF1KE0 GGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLL ::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_001 GGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHR----------DLKLENLLL 40 50 60 70 80 170 180 190 200 210 220 pF1KE0 DKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYN 90 100 110 120 130 140 230 240 250 260 270 280 pF1KE0 PFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLR 150 160 170 180 190 200 290 300 310 320 330 pF1KE0 QATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 210 220 230 240 250 >>NP_777604 (OMIM: 610711) testis-specific serine/threon (328 aa) initn: 1238 init1: 1238 opt: 1238 Z-score: 488.1 bits: 98.6 E(85289): 1.9e-20 Smith-Waterman score: 2154; 97.0% identity (97.0% similar) in 338 aa overlap (1-338:1-328) 10 20 30 40 50 60 pF1KE0 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_777 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_777 ASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKISDFGFA ::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_777 SEPLAGKWFSQLTLGIAYLHSKSIVHR----------DLKLENLLLDKWENVKISDFGFA 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 KMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_777 KMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILY 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 TLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_777 TLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKD 240 250 260 270 280 290 310 320 330 pF1KE0 SWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT :::::::::::::::::::::::::::::::::::::: NP_777 SWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 300 310 320 >>XP_016876715 (OMIM: 610711) PREDICTED: testis-specific (291 aa) initn: 958 init1: 958 opt: 969 Z-score: 391.5 bits: 80.6 E(85289): 4.6e-15 Smith-Waterman score: 1767; 95.4% identity (95.7% similar) in 282 aa overlap (1-282:1-272) 10 20 30 40 50 60 pF1KE0 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKISDFGFA ::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 SEPLAGKWFSQLTLGIAYLHSKSIVHR----------DLKLENLLLDKWENVKISDFGFA 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 KMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILY 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 TLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKD :::::::::::::::::::::::::::::::::::::: .: XP_016 TLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKVQLLIACVAQWRKTQARPLSPL 240 250 260 270 280 290 310 320 330 pF1KE0 SWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT XP_016 L 338 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:30:11 2016 done: Sat Nov 5 18:30:12 2016 Total Scan time: 7.560 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]