FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0757, 330 aa 1>>>pF1KE0757 330 - 330 aa - 330 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2079+/-0.000829; mu= 0.0796+/- 0.050 mean_var=254.5739+/-52.260, 0's: 0 Z-trim(116.5): 46 B-trim: 145 in 1/51 Lambda= 0.080384 statistics sampled from 17077 (17122) to 17077 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.825), E-opt: 0.2 (0.526), width: 16 Scan time: 3.260 The best scores are: opt bits E(32554) CCDS4152.1 PDLIM4 gene_id:8572|Hs108|chr5 ( 330) 2312 280.4 1.4e-75 CCDS47261.1 PDLIM4 gene_id:8572|Hs108|chr5 ( 246) 1570 194.3 8.8e-50 CCDS7441.1 PDLIM1 gene_id:9124|Hs108|chr10 ( 329) 906 117.4 1.7e-26 CCDS75218.1 PDLIM3 gene_id:27295|Hs108|chr4 ( 197) 545 75.3 4.5e-14 CCDS75219.1 PDLIM3 gene_id:27295|Hs108|chr4 ( 276) 545 75.4 5.8e-14 CCDS47172.1 PDLIM3 gene_id:27295|Hs108|chr4 ( 316) 536 74.4 1.3e-13 CCDS3844.1 PDLIM3 gene_id:27295|Hs108|chr4 ( 364) 536 74.5 1.5e-13 >>CCDS4152.1 PDLIM4 gene_id:8572|Hs108|chr5 (330 aa) initn: 2312 init1: 2312 opt: 2312 Z-score: 1470.5 bits: 280.4 E(32554): 1.4e-75 Smith-Waterman score: 2312; 99.7% identity (99.7% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: CCDS41 KLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL 250 260 270 280 290 300 310 320 330 pF1KE0 YCESHAKARVKPPEGYDVVAVYPNAKVELV :::::::::::::::::::::::::::::: CCDS41 YCESHAKARVKPPEGYDVVAVYPNAKVELV 310 320 330 >>CCDS47261.1 PDLIM4 gene_id:8572|Hs108|chr5 (246 aa) initn: 1570 init1: 1570 opt: 1570 Z-score: 1007.2 bits: 194.3 E(32554): 8.8e-50 Smith-Waterman score: 1570; 95.0% identity (96.2% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS :::::::::::::::::::::::::::::::::::::::::::: . : . :.:: CCDS47 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTIPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL CCDS47 CAVTAA >>CCDS7441.1 PDLIM1 gene_id:9124|Hs108|chr10 (329 aa) initn: 924 init1: 474 opt: 906 Z-score: 589.3 bits: 117.4 E(32554): 1.7e-26 Smith-Waterman score: 906; 44.6% identity (67.5% similar) in 332 aa overlap (3-323:4-328) 10 20 30 40 50 pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTEL ... :.::.:::::::::.:: ::.:::: ::::::: :: ::.: ::.::.: CCDS74 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 MTHLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQD----GSP- ::::::::::::: :.:::.:.: : . : : . ...: . ..... : :. :: CCDS74 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 TTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSS-----EATLPAQMSTLHVSPPP . : : .. . . . :..: . .: :. :. :. . : CCDS74 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 SADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPG :.: .: .: ::::.::.: : . :::: :: :: .::. : :: CCDS74 HAQPPSSL------VIDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNK 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 PGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNL :.: :..: ..:..: ... : :: : .: ::::..:: ::. ::::..:.::: :: CCDS74 PSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNL 240 250 260 270 280 290 290 300 310 320 330 pF1KE0 KQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV ::.:.::.....:::.::. :: :::::.::.:.: CCDS74 KQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK 300 310 320 >>CCDS75218.1 PDLIM3 gene_id:27295|Hs108|chr4 (197 aa) initn: 606 init1: 363 opt: 545 Z-score: 366.0 bits: 75.3 E(32554): 4.5e-14 Smith-Waterman score: 550; 43.6% identity (67.6% similar) in 204 aa overlap (123-325:9-197) 100 110 120 130 140 150 pF1KE0 DDSKAQAHRIHIDPEIQDGSPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSE : .: : : : ..:: . . ..:. CCDS75 MPQTVILPGPAPWGFRLSGGIDFNQP--LVITRDGNYF 10 20 30 160 170 180 190 200 210 pF1KE0 ATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSF : : :..:. ..: : :::::.. ::. .:.::::: CCDS75 EHKHNIRPKPFVIPGRSSEPTASVPPESD--------VYRMLHDNRNEPT--QPRQSGSF 40 50 60 70 80 220 230 240 250 260 270 pF1KE0 RYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARD : ::::.. .:.: :.: :... ..:. . .: : .: : .: ::::..::::: CCDS75 RVLQGMVD--DGSD-DRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARD 90 100 110 120 130 140 280 290 300 310 320 330 pF1KE0 KLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV : :::::.:.::.:::::.::::.. .::::.::.::.:::::::.:..::.: CCDS75 KYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA 150 160 170 180 190 >>CCDS75219.1 PDLIM3 gene_id:27295|Hs108|chr4 (276 aa) initn: 827 init1: 363 opt: 545 Z-score: 364.1 bits: 75.4 E(32554): 5.8e-14 Smith-Waterman score: 869; 45.0% identity (66.7% similar) in 327 aa overlap (1-325:1-276) 10 20 30 40 50 60 pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM ::..: : ::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: : CCDS75 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP :: .::.:::. .: :...: : . : :.. .:.::. .:... : :::. .. CCDS75 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKH- 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRS . ::. :. : : ::: : .: :: .: CCDS75 --------NIRPK---PFVIPGR-------SSEPT---------ASVPPESD-------- 120 130 140 180 190 200 210 220 230 pF1KE0 RDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPT :::::.. ::. .:.:::::: ::::.. .:.: :.: :... CCDS75 ----------VYRMLHDNRNEPT--QPRQSGSFRVLQGMVD--DGSD-DRPAGTRSVRAP 150 160 170 180 240 250 260 270 280 290 pF1KE0 ASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDE ..:. . .: : .: : .: ::::..:::::: :::::.:.::.:::::.::::.. CCDS75 VTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEG 190 200 210 220 230 240 300 310 320 330 pF1KE0 RLYCESHAKARVKPPEGYDVVAVYPNAKVELV .::::.::.::.:::::::.:..::.: CCDS75 ELYCETHARARTKPPEGYDTVTLYPKA 250 260 270 >>CCDS47172.1 PDLIM3 gene_id:27295|Hs108|chr4 (316 aa) initn: 796 init1: 363 opt: 536 Z-score: 357.7 bits: 74.4 E(32554): 1.3e-13 Smith-Waterman score: 923; 44.3% identity (71.7% similar) in 332 aa overlap (1-325:1-316) 10 20 30 40 50 60 pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM ::..: : ::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: : CCDS47 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTS--- :: .::.:::. .: :...: : . : :.. .:.::. .:... : :. .: . CCDS47 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 RR--PSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR :: : .... .: : ... :..: . . ... . .: .:. : . :. .:. CCDS47 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGL-IPSSPQNEPTA 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 GLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPR ..: : :::::.. :: ..:.:::::: ::::.. .:.: :.: : CCDS47 SVPPESD--------VYRMLHDNRNEP--TQPRQSGSFRVLQGMVD--DGSD-DRPAGTR 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 NLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGY ... ..:. . .: : .: : .: ::::..:::::: :::::.:.::.:::::.:: CCDS47 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY 230 240 250 260 270 280 300 310 320 330 pF1KE0 FFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV ::.. .::::.::.::.:::::::.:..::.: CCDS47 FFIEGELYCETHARARTKPPEGYDTVTLYPKA 290 300 310 >>CCDS3844.1 PDLIM3 gene_id:27295|Hs108|chr4 (364 aa) initn: 849 init1: 363 opt: 536 Z-score: 356.9 bits: 74.5 E(32554): 1.5e-13 Smith-Waterman score: 842; 42.3% identity (62.9% similar) in 364 aa overlap (9-325:9-364) 10 20 30 40 50 60 pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM ::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: : CCDS38 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGS------- :: .::.:::. .: :...: : . : :.. .:.::. .:... : :::. CCDS38 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 70 80 90 100 110 120 120 130 140 pF1KE0 --------PTTSR---RPSGTGTGPEDGRPSLGSPYGQ--P----------PRFPVPHN- : : ::: : . :: : . : : .:. . CCDS38 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 130 140 150 160 170 180 150 160 170 180 190 pF1KE0 -G----SSEATLPAQ-------MSTLH--VSPPPSADPARGLPRSRDCRVDLGSEVYRML : .. . : : : ::. :: . : . : . : :.::::: CCDS38 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTAS---VPPESDVYRML 190 200 210 220 230 200 210 220 230 240 250 pF1KE0 REP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLP .. :: ..:.:::::: ::::.. .:.: :.: :... ..:. . .: : .: CCDS38 HDNRNEP--TQPRQSGSFRVLQGMVD--DGSD-DRPAGTRSVRAPVTKVHGGSGGAQRMP 240 250 260 270 280 290 260 270 280 290 300 310 pF1KE0 ECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPP : .: ::::..:::::: :::::.:.::.:::::.::::.. .::::.::.::.::: CCDS38 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPP 300 310 320 330 340 350 320 330 pF1KE0 EGYDVVAVYPNAKVELV ::::.:..::.: CCDS38 EGYDTVTLYPKA 360 330 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:04:17 2016 done: Sat Nov 5 03:04:18 2016 Total Scan time: 3.260 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]