FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0777, 331 aa 1>>>pF1KE0777 331 - 331 aa - 331 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3070+/-0.00114; mu= 7.9307+/- 0.068 mean_var=197.7966+/-39.962, 0's: 0 Z-trim(110.0): 88 B-trim: 0 in 0/50 Lambda= 0.091194 statistics sampled from 11189 (11269) to 11189 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.346), width: 16 Scan time: 2.660 The best scores are: opt bits E(32554) CCDS7279.1 HNRNPH3 gene_id:3189|Hs108|chr10 ( 331) 2362 323.2 1.8e-88 CCDS7278.1 HNRNPH3 gene_id:3189|Hs108|chr10 ( 346) 1490 208.5 6.3e-54 CCDS14485.1 HNRNPH2 gene_id:3188|Hs108|chrX ( 449) 762 112.9 5.1e-25 CCDS4446.1 HNRNPH1 gene_id:3187|Hs108|chr5 ( 449) 756 112.1 8.7e-25 CCDS7204.1 HNRNPF gene_id:3185|Hs108|chr10 ( 415) 653 98.5 1e-20 >>CCDS7279.1 HNRNPH3 gene_id:3189|Hs108|chr10 (331 aa) initn: 2362 init1: 2362 opt: 2362 Z-score: 1702.0 bits: 323.2 E(32554): 1.8e-88 Smith-Waterman score: 2362; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KE0 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 RGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 NNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 NNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTP 250 260 270 280 290 300 310 320 330 pF1KE0 DGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY ::::::::::::::::::::::::::::::: CCDS72 DGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 310 320 330 >>CCDS7278.1 HNRNPH3 gene_id:3189|Hs108|chr10 (346 aa) initn: 1460 init1: 1460 opt: 1490 Z-score: 1081.7 bits: 208.5 E(32554): 6.3e-54 Smith-Waterman score: 2322; 95.7% identity (95.7% similar) in 346 aa overlap (1-331:1-346) 10 20 30 40 50 60 pF1KE0 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 70 80 90 100 110 120 130 140 150 160 pF1KE0 RGGYYGAGRGS---------------YGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG ::::::::::: :::::::::::::::::::::::::::::::::: CCDS72 RGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 250 260 270 280 290 300 290 300 310 320 330 pF1KE0 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY :::::::::::::::::::::::::::::::::::::::::::::: CCDS72 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 310 320 330 340 >>CCDS14485.1 HNRNPH2 gene_id:3188|Hs108|chrX (449 aa) initn: 1109 init1: 574 opt: 762 Z-score: 562.7 bits: 112.9 E(32554): 5.1e-25 Smith-Waterman score: 1337; 62.8% identity (78.2% similar) in 349 aa overlap (1-324:93-432) 10 20 pF1KE0 MDWVMKHNGPND---ASDGTVRLRGLPFGC ::::.::.:::. :.:: :::::::::: CCDS14 SEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGC 70 80 90 100 110 120 30 40 50 60 70 80 pF1KE0 SKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKHKERIGHRYIE :::::::::.::::::::.:: .:.::::::::::::::.::::.:: :::::::::::: CCDS14 SKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIE 130 140 150 160 170 180 90 100 110 120 130 pF1KE0 IFRSSRSEIKGFYDPPRRLLG-QRPGPYDRPIGGRG--------GY----YGAGRGSYGG ::.:::.:.. :::::.:.. ::::::::: .::: :. :: :.::: CCDS14 IFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGG 190 200 210 220 230 240 140 150 160 170 180 190 pF1KE0 FDDYGGYNN-YGYGNDGFD-DRMRDGRGMGGHGYGGAGDASSGFHG--GHFVHMRGLPFR .:::::::. ::.:.: : : ::. : :: :..:.:.. :: :::::::.: CCDS14 YDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYG---DGGSSFQSTTGHCVHMRGLPYR 250 260 270 280 290 200 210 220 230 240 250 pF1KE0 ATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIEL :::::: ::::::::.::::.:: :::.::::::::.:::::::::.::: ::::::.:: CCDS14 ATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVEL 300 310 320 330 340 350 260 270 280 290 300 pF1KE0 FLNSTPG-GGSGMGGSGMGGYGRDGMDNQGG-YGS--VGRMGMGNNYS-GGYGTPDGLGG ::::: : .:... : . . . .:: ::: .: ::..:. : :: .. . :: CCDS14 FLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGG 360 370 380 390 400 410 310 320 330 pF1KE0 YGRGGGGSGGYYGQGGMSGGGWRGMY :: ::: ::..::: CCDS14 YG------GGYGGQSSMSGYDQVLQENSSDYQSNLA 420 430 440 >>CCDS4446.1 HNRNPH1 gene_id:3187|Hs108|chr5 (449 aa) initn: 1213 init1: 579 opt: 756 Z-score: 558.4 bits: 112.1 E(32554): 8.7e-25 Smith-Waterman score: 1329; 62.5% identity (77.3% similar) in 352 aa overlap (1-324:93-432) 10 20 pF1KE0 MDWVMKHNGPND---ASDGTVRLRGLPFGC ::::.::.:::. :.:: :::::::::: CCDS44 SEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGC 70 80 90 100 110 120 30 40 50 60 70 80 pF1KE0 SKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKHKERIGHRYIE :::::::::.::::::::::: .:.::::::::::::::.::::.:: :::::::::::: CCDS44 SKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIE 130 140 150 160 170 180 90 100 110 120 130 pF1KE0 IFRSSRSEIKGFYDPPRRLLG-QRPGPYDRPIGGRG--------GY----YGAGRGSYGG ::.:::.:.. :::::.:.. ::::::::: .::: :. :: :.::: CCDS44 IFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGG 190 200 210 220 230 240 140 150 160 170 180 190 pF1KE0 FDDYGGYNN-YGYGNDGFD-DRMRDGRGMGGHGYGGAGDASSGFHG--GHFVHMRGLPFR .:::.:::. ::.:.: : : ::. : :: :..: :.. :: :::::::.: CCDS44 YDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYG---DGGSTFQSTTGHCVHMRGLPYR 250 260 270 280 290 200 210 220 230 240 250 pF1KE0 ATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIEL :::::: ::::::::.::::.:: :::.::::::::.::::::::::::: ::::::.:: CCDS44 ATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVEL 300 310 320 330 340 350 260 270 280 290 300 pF1KE0 FLNSTPGGGSGMGGSGMGGYGRDGMDNQGG-----YGS--VGRMGMGNNYS-GGYGTPDG ::::: :.. ::. : . ... .: ::: .: ::..:. : :: .. . CCDS44 FLNSTAGAS---GGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQL 360 370 380 390 400 410 310 320 330 pF1KE0 LGGYGRGGGGSGGYYGQGGMSGGGWRGMY :::: ::: ::..::: CCDS44 SGGYG------GGYGGQSSMSGYDQVLQENSSDFQSNIA 420 430 440 >>CCDS7204.1 HNRNPF gene_id:3185|Hs108|chr10 (415 aa) initn: 1054 init1: 498 opt: 653 Z-score: 485.6 bits: 98.5 E(32554): 1e-20 Smith-Waterman score: 1165; 57.3% identity (77.4% similar) in 328 aa overlap (1-306:93-414) 10 20 pF1KE0 MDWVMKHNGPNDA---SDGTVRLRGLPFGC ::::.::.:::.: .:: :::::::::: CCDS72 SEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGC 70 80 90 100 110 120 30 40 50 60 70 80 pF1KE0 SKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKHKERIGHRYIE .::::::::.::::::::::: .: .:. ::::::::::.:.::.::::::::::::::: CCDS72 TKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIE 130 140 150 160 170 180 90 100 110 120 130 pF1KE0 IFRSSRSEIKGFYDPPRRLLG-QRPGPYDRP------IG-----G----RGGYYGAGRGS .:.::. :.... ::: .... ::::::::: :: : : : :..: CCDS72 VFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYSTG--- 190 200 210 220 230 140 150 160 170 180 pF1KE0 YGGFDDYGGYNN-YGYGNDGFD-DRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPF :::...:.: .. ::. .: : : :: : :: . . . :: :::::::. CCDS72 YGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDS-EFTVQSTTGHCVHMRGLPY 240 250 260 270 280 290 190 200 210 220 230 240 pF1KE0 RATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIE .:::::: ::::::::.::::.:: :::.::::::::.:::.::::::::. :::::::: CCDS72 KATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIE 300 310 320 330 340 350 250 260 270 280 290 300 pF1KE0 LFLNSTPGGGSGMGGSG-MGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGR :::::: :...: .: : :.: .. :. :... ..... :..::. ...::: CCDS72 LFLNSTTGASNGAYSSQVMQGMGVSA--AQATYSGLESQSVSGCYGAGYSGQNSMGGYD 360 370 380 390 400 410 310 320 330 pF1KE0 GGGGSGGYYGQGGMSGGGWRGMY 331 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:07:06 2016 done: Sat Nov 5 03:07:06 2016 Total Scan time: 2.660 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]